Sanematsu Fumiyuki 實松史幸

… Alternative Names

實松史幸サネマツフミユキ

SANEMATSU FUMIYUKI 實松史幸

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Researcher Number	80381094
Other IDs
Affiliation (Current)	2024: 尚絅大学, 生活科学部, 准教授
Affiliation (based on the past Project Information) *help	2022: 尚絅大学, 生活科学部, 准教授 2020: 宮崎大学, 医学部, 助教 2015 – 2018: 宮崎大学, 医学部, 助教 2012 – 2014: 九州大学, 生体防御医学研究所, 助教 2007: 九州大学, 生体防御医学研究所, 非常勤研究員
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Basic Section 08030:Family and consumer sciences, and culture and living-related / Basic Section 49010:Pathological biochemistry-related / Functional biochemistry Except Principal Investigator Biological Sciences
Keywords	Principal Investigator 細胞骨格 / 細胞老化 / 糖尿病 / 食後高血糖 / フォルミンタンパク質 / 心筋 / 泡沫細胞 / マクロピノサイトーシス / 動脈硬化 / マクロファージ … More / ラッフル膜 / ホスファチジン酸 / Rac / DOCK180 / Rac活性化分子 / ラッフル膜形成 … More Except Principal Investigator Rac / DOCK2 / 樹状細胞 / 小胞輸送 / アレルギー / サイトカイン受容体 / タンパク質分解 / 活性化 / タンパク分解 / ヘルパーT細胞 / 形質細胞樣樹状細胞 / Nef / T細胞 / HIV Less

食後高血糖における新規細胞老化シグナルの増大およびその作用機序の総括的解明Principal Investigator
- Principal Investigator
  
  實松史幸
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Shokei University
細胞骨格重合因子に依存した異種細胞間におけるコミュニケーション機構の解析Principal Investigator
- Principal Investigator
  
  實松史幸
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  University of Miyazaki
Functional analysis of formin protein Fhod1 in mousePrincipal Investigator
- Principal Investigator
  
  Sanematsu Fumiyuki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
The regulatory mechanism and the role of CDM family protein in atherosclerosisPrincipal Investigator
- Principal Investigator
  
  Sanematsu Fumiyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  University of Miyazaki
  Kyushu University
Spatio-temporal analysis of DOCK180 during dorsal ruffle formationPrincipal Investigator
- Principal Investigator
  
  SANEMATSU FUMIYUKI
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kyushu University
HIV NefによるT細胞機能異常における宿主シグナル伝達分子DOCK2の役割
- Principal Investigator
  
  福井宣規
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
免疫応答の質的制御に関わるサイトカイン受容体のタンパク質分解機構の解明
- Principal Investigator
  
  福井宣規
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University

All 2023 2022 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] 女子大生における血糖値スパイクの現状調査と菊芋チップスによる症状改善の検討2023
- Author(s)
  實松史幸, 藤田紗香
- Journal Title
  
  尚絅大学研究紀要　自然科学編
  
  Volume: 55 Pages: 147-156
- Open Access
- Data Source
  KAKENHI-PROJECT-22K02128
[Journal Article] Fhod1, an actin-organizing formin family protein, is dispensable for cardiac development and function in mice2019
- Author(s)
  Sanematsu, F., Kanai, A., Ushijima, T., Shiraishi, A., Abe, T., Kage, Y., Sumimoto, H., and Takeya, R.
- Journal Title
  
  Cytoskeleton
  
  Volume: 印刷中 Issue: 2 Pages: 219-229
- DOI
  10.1002/cm.21523
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26111009, KAKENHI-PROJECT-16K08627, KAKENHI-PROJECT-19K07355, KAKENHI-PROJECT-19K11793
[Journal Article] DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activation Rac1P29S mutation.2018
- Author(s)
  Tomino T, Tajiri H, Tatsuguchi T, Shirai T, Oisaki K, Matsunaga S, Sanematsu F, Sakata D, Yoshizumi T, Maehara Y, Kanai M, Cote JF, Fukui Y, Uruno T
- Journal Title
  
  Biochem.Biophys.Res.Commun.
  
  Volume: 497 Issue: 1 Pages: 298-304
- DOI
  10.1016/j.bbrc.2018.02.073
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02497, KAKENHI-PROJECT-16K15620, KAKENHI-PROJECT-18H02406, KAKENHI-PROJECT-16K08627, KAKENHI-PROJECT-15K08525
[Journal Article] The Rac activator DOCK2 mediates plasma cell differentiation and IgG antibody production.2018
- Author(s)
  Ushijima M, Uruno T, Nishikimi A, Sanematsu F, Kamikaseda Y, Kunimura K, Sakata D, Okada T, Fukui Y
- Journal Title
  
  Front Immunol.
  
  Volume: 9 Pages: 243-243
- DOI
  10.3389/fimmu.2018.00243
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02497, KAKENHI-PROJECT-18H02406, KAKENHI-PROJECT-16K08627, KAKENHI-PROJECT-15K08525
[Journal Article] The AP-1 transcription factor JunB is required for Th17 cell differentiation2017
- Author(s)
  Yamazaki Soh、Tanaka Yoshihiko、Araki Hiromitsu、Kohda Akira、Sanematsu Fumiyuki、Arasaki Tomoko、Duan Xuefeng、Miura Fumihito、Katagiri Takaharu、Shindo Ryodai、Nakano Hiroyasu、Ito Takashi、Fukui Yoshinori、Endo Shogo、Sumimoto Hideki
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 17402-17402
- DOI
  10.1038/s41598-017-17597-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01378, KAKENHI-PROJECT-16K08627, KAKENHI-PROJECT-16K08747, KAKENHI-PROJECT-17K19533, KAKENHI-PUBLICLY-17H05804, KAKENHI-PLANNED-26110003, KAKENHI-PLANNED-26111009, KAKENHI-PROJECT-16H02497, KAKENHI-PROJECT-15H03103, KAKENHI-PROJECT-17H04069, KAKENHI-PROJECT-17H04371, KAKENHI-PROJECT-15J03454, KAKENHI-PROJECT-16K15681, KAKENHI-PROJECT-16K15792, KAKENHI-PROJECT-17K08994
[Journal Article] DOCK8 Regulates Macrophage Migration through Cdc42 Activation and LRAP35a Interaction.2017
- Author(s)
  Shiraishi A, Uruno T, Sanematsu F, Ushijima M, Sakata D, Hara T, Fukui Y.
- Journal Title
  
  J Biol Chem
  
  Volume: 292 Issue: 6 Pages: 2191-2202
- DOI
  10.1074/jbc.m116.736306
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111007, KAKENHI-PROJECT-16H02497, KAKENHI-PROJECT-26430115, KAKENHI-PROJECT-15K08525, KAKENHI-PROJECT-16K08627
[Journal Article] Targeting Ras-driven cancer cell survival and invasion through selective inhibition of DOCK12017
- Author(s)
  Tajiri H, Uruno T, Shirai T, Takaya D, Matsunaga S, Setoyama D, Watanabe M, Kukimoto-Niino M, Oisaki K, Ushijima M, Sanematsu F, Honma T, Terada T, Oki E, Shirasawa S, Maehara Y, Kang D, Cote J-F, Yokoyama S, Kanai M, Fukui Y
- Journal Title
  
  Cell Reports
  
  Volume: 19 Issue: 5 Pages: 969-980
- DOI
  10.1016/j.celrep.2017.04.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26430115, KAKENHI-PROJECT-15K06987, KAKENHI-PROJECT-16K08627, KAKENHI-PROJECT-16H02497, KAKENHI-PROJECT-17H01550
[Journal Article] Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus.2015
- Author(s)
  Yanagihara T, Sanematsu F, Sato T, Uruno T, Duan X, Tomino T, Harada Y, Watanabe M, Wang Y, Tanaka Y, Nakanishi Y, Suyama M, Yoshinori F.
- Journal Title
  
  Nature Communications
  
  Volume: 6 Issue: 1 Pages: 8820-8820
- DOI
  10.1038/ncomms9820
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26430115, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111007, KAKENHI-PROJECT-25251015, KAKENHI-PROJECT-26670287, KAKENHI-PROJECT-26670822, KAKENHI-PROJECT-26870420, KAKENHI-PROJECT-26293393
[Journal Article] DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation.2014
- Author(s)
  Ogawa K, Tanaka Y, Uruno T, Duan X, Harada Y, et al.
- Journal Title
  
  J. Exp. Med.
  
  Volume: (In press) Issue: 7 Pages: 1407-1419
- DOI
  10.1084/jem.20131926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J03868, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111007, KAKENHI-PROJECT-24590586, KAKENHI-PUBLICLY-25111508, KAKENHI-PROJECT-25251015, KAKENHI-PROJECT-26293393, KAKENHI-PROJECT-26430115, KAKENHI-PROJECT-26670287, KAKENHI-PROJECT-26670822, KAKENHI-PROJECT-26860332, KAKENHI-PROJECT-26870420
[Journal Article] DOCK2 and DOCK5 act additively in neutrophils to regulate chemotaxis, superoxide production, and extracellular trap formation.2014
- Author(s)
  Watanabe M, Terasawa M, Miyano K, Yanagihara T, Uruno T, Sanematsu F, Nishikimi A, Cote JF, Sumimoto H, Fukui Y.
- Journal Title
  
  J Immunol.
  
  Volume: 193 Issue: 11 Pages: 5660-5667
- DOI
  10.4049/jimmunol.1400885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111007, KAKENHI-PROJECT-24590586, KAKENHI-PROJECT-25251015, KAKENHI-PLANNED-26111009, KAKENHI-PROJECT-26430115, KAKENHI-PROJECT-26670287, KAKENHI-PROJECT-26870420
[Journal Article] 心血管形成におけるDOCK180の機能とその制御機構2013
- Author(s)
  實松史幸
- Journal Title
  
  感染　炎症　免疫
  
  Volume: 42 Pages: 50-53
- Data Source
  KAKENHI-PROJECT-24770127
[Journal Article] Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation2013
- Author(s)
  Sanematsu, F., Nishikimi, A., Watanabe, M., Hongu, T., Tanaka, Y., Kanaho, Y., Côté, J.F., Fukui, Y.
- Journal Title
  
  J Biol. Chem.
  
  Volume: 288(12) Pages: 8092-100
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770127
[Journal Article] The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation2013
- Author(s)
  Sakai Y, Tanaka Y, Yanagihara T, Watanabe M, Duan X, Terasawa M, Nishikimi A, Sanematsu F, Fukui Y.
- Journal Title
  
  Blood
  
  Volume: 122 Issue: 3 Pages: 386-393
- DOI
  10.1182/blood-2012-12-475897
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111007, KAKENHI-PROJECT-24590586, KAKENHI-PROJECT-24770127, KAKENHI-PUBLICLY-25111508, KAKENHI-PROJECT-25251015
[Journal Article] Phosphatidic acid-dependent recruitment and function of the Rac activator DOCK1 during dorsal ruffle formation.2013
- Author(s)
  Sanematsu F, Nishikimi A, Watanabe M, Hongu T, Tanaka Y, Kanaho Y, Cote JF, Fukui Y
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Issue: 12 Pages: 8092-8100
- DOI
  10.1074/jbc.m112.410423
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22247017, KAKENHI-ORGANIZER-24111001, KAKENHI-PROJECT-24590586, KAKENHI-PROJECT-24770127, KAKENHI-PROJECT-24890028, KAKENHI-PLANNED-24111007
[Journal Article] The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation2013
- Author(s)
  Sakai, Y., Tanaka, Y., Yanagihara, T., Watanabe, M., Duan, X., Terasawa, M., Nishikimi, A., Sanematsu, F., Fukui. Y.
- Journal Title
  
  Blood
  
  Volume: 122(3) Pages: 386-93
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770127
[Journal Article] Dimerization of DOCK2 is essential for DOCK2-mediated Rac activation and lymphocyte migration2012
- Author(s)
  Terasawa, M., Uruno, T., Mori, S., Kukimoto-Niino, M., Nishikimi, A., Sanematsu, F., Tanaka, Y., Yokoyama, S., Fukui, Y.
- Journal Title
  
  PLoS One
  
  Volume: 7(9)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770127
[Journal Article] DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses2012
- Author(s)
  Harada, Y., Tanaka, Y., Terasawa, M., Pieczyk, M., Habiro, K., Katakai, T., Hanawa-Suetsugu, K., Kukimoto-Niino, M., Nishizaki, T., Shirouzu, M, Duan, X., Uruno, T., Nishikimi, A., Sanematsu, F., Yokoyama, S., Stein, J.V., Kinashi, T., Fukui, Y.
- Journal Title
  
  Blood
  
  Volume: 119(19) Pages: 4451-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770127
[Journal Article] Blockade of inflammatory responses by a small-molecule inhibitor of the Rac activator DOCK22012
- Author(s)
  Nishikimi, A., Uruno, T., Duan, X., Cao, Q., Okamura, Y., Saitoh, T., Saito, N., Sakaoka. S., Du, Y., Suenaga, A., Kukimoto-Niino, M., Miyano, K., Gotoh, K., Okabe, T., Sanematsu, F., Tanaka, Y., Sumimoto, H., Honma, T., Yokoyama, S., Nagano, T., Kohda, D., Kanai, M., Fukui, Y.
- Journal Title
  
  Chem. Biol.
  
  Volume: 19(4) Pages: 488-97
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24770127
[Presentation] 食後高血糖における細胞老化分子の解析2022
- Author(s)
  實松史幸、菊池秀彦
- Organizer
  第95回日本生化学大会
- Data Source
  KAKENHI-PROJECT-22K02128
[Presentation] フォルミン蛋白質Fhod1の発現細胞の同定と機能解析.2018
- Author(s)
  實松史幸, 武谷立
- Organizer
  第42回蛋白質と酵素の構造と機能に関する九州シンポジウム
- Data Source
  KAKENHI-PROJECT-16K08627
[Presentation] マウス心臓におけるフォルミン蛋白質Fhood1の機能解析2017
- Author(s)
  實松史幸、金井亜未、鹿毛陽子、牛島智基、住本英樹、武谷立
- Organizer
  生命科学系学会合同年次大会(ConBio2017)
- Data Source
  KAKENHI-PROJECT-16K08627
[Presentation] フォルミン蛋白質Fhod1のマウス心臓における生理的役割2017
- Author(s)
  金井亜未、實松史幸、牛島智基、武谷立、住本英樹
- Organizer
  平成29年度日本生化学会九州支部例会
- Data Source
  KAKENHI-PROJECT-16K08627
[Presentation] アクチン重合制御因子Fhod1およびFhod3の生理的機能2016
- Author(s)
  1）武谷　立、實松史幸、根本隆行、鹿毛陽子、松山　翔、Hikmawan Wahyu Sulistomo
- Organizer
  第9回トランスポーター研究会九州部会
- Place of Presentation
  宮崎市（宮崎市民プラザ）
- Year and Date
  2016-10-01
- Data Source
  KAKENHI-PROJECT-16K08627
[Presentation] Dorsal ruffle形成時におけるDOCK1の役割とその制御2012
- Author(s)
  實松史幸, 錦見昭彦, 渡邉真裕紀, 本宮綱記, 田中芳彦, 金保安則, Jean-Francois Cote, 福井宣規
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Year and Date
  2012-12-12
- Data Source
  KAKENHI-PROJECT-24770127
[Presentation] Role of DOCK1 and Its Regulation during Dorsal ruffle formation.
- Author(s)
  Sanematsu F et al.
- Organizer
  The 35th Annual Meeting of the Molecular Biology Society of Japan
- Place of Presentation
  Marinemesse Fukuoka, Japan
- Data Source
  KAKENHI-PROJECT-24770127

1. 福井宣規 (60243961)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. 錦見昭彦 (70404019)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 武谷立 (50335981)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. 菊池秀彦 (10301384)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 中野裕康

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 宇留野武人

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 渡辺武

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 田中芳彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 住本英樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sanematsu Fumiyuki 實松 史幸

實松 史幸 サネマツ フミユキ

SANEMATSU FUMIYUKI 實松 史幸

Research Projects

Research Products

Co-Researchers

食後高血糖における新規細胞老化シグナルの増大およびその作用機序の総括的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞骨格重合因子に依存した異種細胞間におけるコミュニケーション機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of formin protein Fhod1 in mousePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The regulatory mechanism and the role of CDM family protein in atherosclerosisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Spatio-temporal analysis of DOCK180 during dorsal ruffle formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

HIV NefによるT細胞機能異常における宿主シグナル伝達分子DOCK2の役割

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

免疫応答の質的制御に関わるサイトカイン受容体のタンパク質分解機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] 女子大生における血糖値スパイクの現状調査と菊芋チップスによる症状改善の検討2023

Author(s)

Journal Title

Data Source

[Journal Article] Fhod1, an actin-organizing formin family protein, is dispensable for cardiac development and function in mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DOCK1 inhibition suppresses cancer cell invasion and macropinocytosis induced by self-activation Rac1P29S mutation.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Rac activator DOCK2 mediates plasma cell differentiation and IgG antibody production.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The AP-1 transcription factor JunB is required for Th17 cell differentiation2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DOCK8 Regulates Macrophage Migration through Cdc42 Activation and LRAP35a Interaction.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Targeting Ras-driven cancer cell survival and invasion through selective inhibition of DOCK12017

Author(s)

Journal Title

Sanematsu Fumiyuki 實松史幸

實松史幸サネマツフミユキ

SANEMATSU FUMIYUKI 實松史幸