Nakajo Koichi 中條浩一

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NAKAJO Koichi 中條浩一

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Researcher Number	80390699
Other IDs	https://orcid.org/0000-0003-0766-7281
Affiliation (Current)	2026: 自治医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2018 – 2024: 自治医科大学, 医学部, 教授 2016 – 2017: 大阪医科大学, 医学部, 准教授 2006 – 2014: 生理学研究所, 分子生理研究系, 助教
Review Section/Research Field	Principal Investigator General physiology / Basic Section 48020:Physiology-related / Complex systems Except Principal Investigator General physiology / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator イオンチャネル / カリウムチャネル / 不整脈 / 電気生理学 / QT延長症候群 / 複合体 / 電位センサー / KCNE1 / KCNQ1 / 電位依存性カリウムチャネル … More / 修飾サブユニット / 全反射蛍光顕微鏡 / 分子生物学 / 光生理学 / 生理学 / HCN4チャネル / 心臓 / ゼブラフィッシュ / KCNQ1チャネル / KCNE / 蛍光イメージング / イメージング / ストイキオメトリー / 心筋 / 構造解析 / 電気生理 / HCNチャネル / 1分子イメージング / 電位センサードメイン / ゲノム編集 / 腸管神経 / オプトジェネティクス / KCNEタンパク質 / QT短縮症候群 / 電位依存性 / KCNQチャネル / FRET / Kv4 / モデル / 一分子イメージング / ホヤ / 生物物理学 / 生物物理 … More Except Principal Investigator 電位依存性 / GPRC / 構造変化 / 膜電位依存性 / FRET / Gタンパク質共役型受容体 / 振動分光法 / 分子科学 / 生物物理学 / イオンチャネル / 赤外分光法 Less

Understanding of the Kv/HCN channel gating mechanism based on structural informationPrincipal Investigator
- Principal Investigator
  
  中條浩一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Jichi Medical University
Detection of molecular configuration of ion channel complexes in vivo and elucidation of their physiological functionsPrincipal Investigator
- Principal Investigator
  
  NAKAJO Koichi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Jichi Medical University
Functional analysis of auxiliary subunits of KCNQ1 channels in the heartPrincipal Investigator
- Principal Investigator
  
  NAKAJO Koichi
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jichi Medical University
  Osaka Medical College
Analysis of the voltage dependence of Gq coupled receptors
- Principal Investigator
  
  MICHIHIRO TATEYAMA
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
ストイキオメトリーの違いを考慮したＫＣＮＱ１チャネル活性化機構の光生理学的解析Principal Investigator
- Principal Investigator
  
  中條浩一
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  National Institute for Physiological Sciences
Stoichiometry and current kinetics of KCNQ1-KCNE1 ion channel complexPrincipal Investigator
- Principal Investigator
  
  NAKAJO Koichi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
Functional expression of mammalian ion channels and analysis of the molecular mechanisms
- Principal Investigator
  
  FURUTANI Yuji
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Institute for Molecular Science
ストイキオメトリーの多様性を考慮に入れた新しい心筋カリウムチャネルモデルの確立Principal Investigator
- Principal Investigator
  
  中條浩一
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  National Institute for Physiological Sciences
Detection of state-dependent change of the stoichiometry of KCNQ1-KCNE1 complex by single molecule imagingPrincipal Investigator
- Principal Investigator
  
  NAKAJO Koichi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
Mechanisms of KCNQ1 channel modulation by KCNE proteins revealed by ascidian KCNQ1 homologuePrincipal Investigator
- Principal Investigator
  
  NAKAJO Koichi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences
KCNQ1チャネルのKCNE1会合による活性化遅延機構の電気・光生理学的解析Principal Investigator
- Principal Investigator
  
  中條浩一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  National Institute for Physiological Sciences

[Journal Article] Modulation of potassium channels by transmembrane auxiliary subunits via voltage‐sensing domains2024
- Author(s)
  Nakajo Koichi、Kasuya Go
- Journal Title
  
  Physiological Reports
  
  Volume: 12 Issue: 6
- DOI
  10.14814/phy2.15980
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06786
[Journal Article] History and outlook of voltage-gated potassium channel research2023
- Author(s)
  中條浩一
- Journal Title
  
  生化学
  
  Volume: 95 Issue: 3 Pages: 296-309
- DOI
  10.14952/SEIKAGAKU.2023.950296
- ISSN
  0037-1017
- Year and Date
  2023-06-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06786
[Journal Article] Dual allosteric modulation of voltage and calcium sensitivities of the Slo1-LRRC channel complex2023
- Author(s)
  Yamanouchi Daichi、Kasuya Go、Nakajo Koichi、Kise Yoshiaki、Nureki Osamu
- Journal Title
  
  Molecular Cell
  
  Volume: 83 Issue: 24 Pages: 4555-4569.e4
- DOI
  10.1016/j.molcel.2023.11.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19263, KAKENHI-PROJECT-21K06786, KAKENHI-PROJECT-23K23819
[Journal Article] Two HCN4 Channels Play Functional Roles in the Zebrafish Heart2022
- Author(s)
  Liu Jiaying、Kasuya Go、Zempo Buntaro、Nakajo Koichi
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 13 Pages: 1-19
- DOI
  10.3389/fphys.2022.901571
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06786
[Journal Article] Optimized tight binding between the S1 segment and KCNE3 is required for the constitutively open nature of the KCNQ1-KCNE3 channel complex2022
- Author(s)
  Kasuya Go、Nakajo Koichi
- Journal Title
  
  eLife
  
  Volume: 11 Pages: 1-15
- DOI
  10.7554/elife.81683
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06786, KAKENHI-PROJECT-20H03200
[Journal Article] Structural basis of gating modulation of Kv4 channel complexes.2021
- Author(s)
  Kise Y, Kasuya G, Okamoto HH, Yamanouchi D, Kobayashi K, Kusakizako T, Nishizawa T, Nakajo K, Nureki O.
- Journal Title
  
  Nature
  
  Volume: 599 Issue: 7883 Pages: 158-164
- DOI
  10.1038/s41586-021-03935-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06207, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-20H03216, KAKENHI-PROJECT-21K06786, KAKENHI-PROJECT-20K15754, KAKENHI-PROJECT-22KJ0604, KAKENHI-PROJECT-21H05037, KAKENHI-PROJECT-20H03200
[Journal Article] Triad interaction stabilizes the voltage sensor domains in a constitutively open KCNQ1-KCNE3 channel2021
- Author(s)
  Go Kasuya, Koichi Nakajo
- Journal Title
  
  bioRxiv
  
  Volume: 該当なし
- DOI
  10.1101/2021.04.05.438515
- Open Access
- Data Source
  KAKENHI-PROJECT-17K08552
[Journal Article] Gastrointestinal Neurons Expressing HCN4 Regulate Retrograde Peristalsis2020
- Author(s)
  Fujii Kensuke、Nakajo Koichi、Egashira Yoshihiro、Yamamoto Yasuhiro、Kitada Kazuya、Taniguchi Kohei、Kawai Masaru、Tomiyama Hideki、Kawakami Koichi、Uchiyama Kazuhisa、Ono Fumihito
- Journal Title
  
  Cell Reports
  
  Volume: 30 Issue: 9 Pages: 2879-2888
- DOI
  10.1016/j.celrep.2020.02.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08552, KAKENHI-PROJECT-19K06460, KAKENHI-PROJECT-17K15152, KAKENHI-PROJECT-18K08554, KAKENHI-PROJECT-18K06882
[Journal Article] Gating modulation of the KCNQ1 channel by KCNE proteins studied by voltage-clamp fluorometry2019
- Author(s)
  Nakajo Koichi
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 16 Issue: 0 Pages: 121-126
- DOI
  10.2142/biophysico.16.0_121
- NAID
  130007652558
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08552
[Journal Article] Structural properties determining low K+affinity of the selectivity filter in the TWIK1 K+channel2018
- Author(s)
  Tsukamoto Hisao、Higashi Masahiro、Motoki Hideyoshi、Watanabe Hiroki、Ganser Christian、Nakajo Koichi、Kubo Yoshihiro、Uchihashi Takayuki、Furutani Yuji
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 293 Issue: 18 Pages: 6969-6984
- DOI
  10.1074/jbc.ra118.001817
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16KT0165, KAKENHI-PROJECT-17K05757, KAKENHI-PROJECT-17K08552, KAKENHI-PROJECT-17K15109, KAKENHI-PROJECT-26708002, KAKENHI-PUBLICLY-16H00758, KAKENHI-PUBLICLY-16H00778, KAKENHI-PUBLICLY-16H00830, KAKENHI-PROJECT-15H03540, KAKENHI-PROJECT-17H04021
[Journal Article] Analysis of Voltage Sensor Movement in KCNQ1-KCNE1 Channels by Voltage Clamp Fluorometry2018
- Author(s)
  NAKAJO Koichi
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 58 Issue: 3 Pages: 144-148
- DOI
  10.2142/biophys.58.144
- NAID
  130007378611
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08552
[Journal Article] Post-translational palmitoylation controls the voltage gating and lipid raft association of the CALHM1 channel.2017
- Author(s)
  Taruno A, Sun H, Nakajo K, Murakami T, Ohsaki Y, Kido MA, Ono F, Marunaka Y.
- Journal Title
  
  Journal of Physiology
  
  Volume: 595 Issue: 18 Pages: 6121-6145
- DOI
  10.1113/jp274164
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08552, KAKENHI-PROJECT-16K15181, KAKENHI-PROJECT-16K18991
[Journal Article] KCNQ1 channel modulation by KCNE proteins via the voltage-sensing domain2015
- Author(s)
  Koichi Nakajo, Yoshihiro Kubo
- Journal Title
  
  Journal of Physiology
  
  Volume: in press Issue: 12 Pages: 2617-2625
- DOI
  10.1113/jphysiol.2014.287672
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590292, KAKENHI-PUBLICLY-25136724
[Journal Article] The stoichiometry and biophysical properties of the Kv4 potassium channel complex with K+ channel-interacting protein (KChIP) subunits are variable, depending on the relative expression level2014
- Author(s)
  Masahiro Kitazawa, Yoshihiro Kubo, Koichi Nakajo
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 289 Issue: 25 Pages: 17597-17609
- DOI
  10.1074/jbc.m114.563452
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590292, KAKENHI-PUBLICLY-25136724
[Journal Article] Steric hindrance between S4 and S5 of the KCNQ1/KCNE1 channel hampers pore opening2014
- Author(s)
  Koichi Nakajo, Yoshihiro Kubo
- Journal Title
  
  Nature Communications
  
  Volume: 5 Issue: 1 Pages: 4100-4100
- DOI
  10.1038/ncomms5100
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24590292, KAKENHI-PUBLICLY-25136724
[Journal Article] 電位依存性カリウムチャネルKCNQ1の複合体ストイキオメトリーと機能制御機構2013
- Author(s)
  中條浩一、久保義弘
- Journal Title
  
  生物物理
  
  Volume: 53 Pages: 313-316
- NAID
  10031203608
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590292
[Journal Article] 電位依存性カリウムチャネルKCNQ1の複合体ストイキオメトリーと機能制御機構2013
- Author(s)
  中條浩一、久保義弘
- Journal Title
  
  生物物理
  
  Volume: 53 Pages: 313-316
- NAID
  10031203608
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25136724
[Journal Article] Nano-environmental changes by KCNE proteins modify KCNQ channel function2011
- Author(s)
  Nakajo K, Kubo Y
- Journal Title
  
  Channels
  
  Volume: 5 Issue: 5 Pages: 397-401
- DOI
  10.4161/chan.5.5.16468
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23136518
[Journal Article] KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 ortholog2011
- Author(s)
  Nakajo K, Nishino A, Okamura Y, Kubo Y.
- Journal Title
  
  J. Gen. Physiol
  
  Volume: 138 Pages: 521-535
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] Nano-environmental changes by KCNE proteins modify KCNQ channel function2011
- Author(s)
  Nakajo K, Kubo Y.
- Journal Title
  
  Channels
  
  Volume: 5 Pages: 397-401
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] KCNQ1 subdomains involved in KCNE modulation revealed by an invertebrate KCNQ1 orthologue.2011
- Author(s)
  Nakajo K, Nishino A, Okamura Y, Kubo Y
- Journal Title
  
  J Gen Physiol.
  
  Volume: 138 Issue: 5 Pages: 521-535
- DOI
  10.1085/jgp.201110677
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21229003, KAKENHI-PROJECT-22790223, KAKENHI-PUBLICLY-23136518, KAKENHI-PROJECT-23650210
[Journal Article] Identification and characterization of Cs^+ -permeable K^+ channel current in mouse cerebellar Purkinje cells in lobules 9 and 10 evoked by molecular layer stimulation2010
- Author(s)
  Ishii H, Nakajo K, Yanagawa Y, Kubo Y
- Journal Title
  
  Eur J Neurosci
  
  Volume: 32 Pages: 736-748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] ATP受容体チャネルP2X2の構造と機能の状況依存的変化(総説)2010
- Author(s)
  久保義弘、藤原祐一郎、Batu Keceli、中條浩一
- Journal Title
  
  Brain Nerve
  
  Volume: 62 Pages: 1323-1329
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] The Met268Pro mutation of mouse TRPA1 changes the effect of caffeine from activation to suppression2010
- Author(s)
  Nagatomo K, Ishii H, Yamamoto T, Nakajo K, Kubo Y
- Journal Title
  
  Biophys J
  
  Volume: 99 Pages: 3609-3618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] Stoichiometry of the KCNQ1-KCNE1 ion channel complex2010
- Author(s)
  Nakajo K, Ulbrich MH, Kubo Y, Isacoff EY
- Journal Title
  
  Proc. Natl. Acad. Sci. U. S. A.
  
  Volume: 107 Pages: 18862-18867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] ATP受容体チャネルP2X2の構造と機能の状況依存的変化2010
- Author(s)
  久保義弘、藤原祐一郎、Keceli Batu、中條浩一
- Journal Title
  
  Brain and nerve
  
  Volume: 62 Pages: 1323-1329
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] Identification and characterization of Cs+-permeable K+ channel current in mouse cerebellar Purkinje cells in lobules 9 and 10 evoked by molecular layer stimulation2010
- Author(s)
  Ishii H, Nakajo K, Yanagawa Y, Kubo Y.
- Journal Title
  
  Eur J Neurosci (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790184
[Journal Article] Identification and characterization of Cs^<+-> permeable K^+channel current in mouse cerebellar Purkinje cells in lobules 9 and 10 evoked by molecular layer stimulation2010
- Author(s)
  Ishii H, Nakajo K, Yanagawa Y, Kubo Y
- Journal Title
  
  Eur. J. Neurosci
  
  Volume: 32 Pages: 736-748
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] The Met268Pro mutation of mouse TRPA1 changes the effect of caffeine from activation to suppression2010
- Author(s)
  Nagatomo K, Ishii H, Yamamoto T, Nakajo K, Kubo Y
- Journal Title
  
  Biophys. J
  
  Volume: 99 Pages: 3609-3618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] Stoichiometry of the KCNQ1 - KCNE1 ion channel complex2010
- Author(s)
  Nakajo K, Ulbrich MH, Kubo Y, Isacoff EY
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 107 Pages: 18862-18867
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790223
[Journal Article] Dynamic aspects of functional regulation of the ATP receptor channel P2X_22009
- Author(s)
  Kubo Y, Fujiwara Y, Keceli B, Nakajo K
- Journal Title
  
  Journal of Physiology 587
  
  Pages: 5317-5324
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790184
[Journal Article] Dynamic aspects of functional regulation of the ATP receptor channel P2X22009
- Author(s)
  Kubo Y, Fujiwara Y, Keceli B, Nakajo K.
- Journal Title
  
  J Physiol. 587(Pt22)
  
  Pages: 5317-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790184
[Journal Article] Voltage-and [ATP]-dependent gating of the P2X (2) ATP receptor channel2009
- Author(s)
  Fujiwara Y, Keceli, B, Nakajo K & Kubo Y
- Journal Title
  
  Journal of General Physiology 133
  
  Pages: 93-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790184
[Journal Article] Voltage- and [ATP]-dependent gating of the P2X2ATP receptor channel2009
- Author(s)
  Fujiwara Y, Keceli B, Nakajo K, Kubo Y.
- Journal Title
  
  J Gen Physiol 133(1)
  
  Pages: 93-109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790184
[Journal Article] Second coiled-coil domain of KCNQ channel controls current expression and subfamily specific heteromultimerization by salt bridge networks2008
- Author(s)
  Nakajo K, Kubo Y
- Journal Title
  
  J Physiol. 586
  
  Pages: 2827-40
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790184
[Journal Article] Cooper EC Ion channel clustering at the axon initial segment and node of Ranvier evolved sequentially in early chordates2008
- Author(s)
  Hill AS, Nishino A, Nakajo K, Zhang G, Fineman JR, Selzer ME, Okamura Y
- Journal Title
  
  PLoS Genet. 4(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790184
[Journal Article] Ion channel clustering at the axon initial segment and node of ranvier evolved sequentially in early chordates2008
- Author(s)
  Hill AS, Nishino A, Nakajo K, Zhang G, Fineman JR, et.al.
- Journal Title
  
  PLoS Genetics 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790184
[Journal Article] Second coiled-coil domain of KCNQ channel controls current expression and subfamily specific heteromultimerization by salt bridge networks2008
- Author(s)
  Koichi Nakajo & Yoshihiro Kubo
- Journal Title
  
  Journal of Physiology 586
  
  Pages: 2827-2840
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790184
[Journal Article] KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel2007
- Author(s)
  Koichi Nakajo & Yoshihiro Kubo
- Journal Title
  
  Journal of General Physiology 130
  
  Pages: 269-281
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790164
[Presentation] Functional role of positive charges on the extracellular side of S4 in HCN channels2025
- Author(s)
  Kaei Ryu, Go Kasuya, Koichi Nakajo
- Organizer
  The Biophysical Society Annual Meeting (BPS2025)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K02211
[Presentation] Gating Modulation Mechanism via Voltage Sensor in HCN Channels2025
- Author(s)
  Kaei Ryu, Go Kasuya, Koichi Nakajo
- Organizer
  第130回日本解剖学会・第102回日本生理学会・第98回日本薬理合同学会
- Invited
- Data Source
  KAKENHI-PROJECT-24K02211
[Presentation] The role of the extracellular region of the S4 segment in HCN channel gating: Why is the S4 segment of the HCN channel long?2024
- Author(s)
  Kaei Ryu, Go Kasuya, Koichi Nakajo
- Organizer
  Ion channel modulation symposium 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K02211
[Presentation] A unique extracellular S4-S5 coupling in HCN channels regulates the voltage-dependent gating2024
- Author(s)
  Jiaying Liu, Go Kasuya, Koichi Nakajo
- Organizer
  日本生理学会第101回大会
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Structure-guided approach to elucidate modulation of voltage-gated potassium channels through voltage-sensing domain by auxiliary subunits2024
- Author(s)
  Koichi Nakajo, Go Kasuya
- Organizer
  日本生理学会第101回大会
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] HCNチャネルにおける細胞外S4-S5カップリングによる電位依存性ゲーティング調節機構2024
- Author(s)
  劉嘉瑩、糟谷豪、中條浩一
- Organizer
  第254回日本生理学東京談話会
- Data Source
  KAKENHI-PROJECT-24K02211
[Presentation] Ca2+ influx through slow muscle-type nichotinic AChR contributes to slow muscle contraction2024
- Author(s)
  Buntaro Zempo, Fumihito Ono, Koichi Nakajo
- Organizer
  日本生理学会第101回大会
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Interaction sites required for the KCNQ1 channel inhibition by KCNE42024
- Author(s)
  Minami Nakmura, Go Kasuya, Koichi Nakajo
- Organizer
  日本生理学会第101回大会
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Physiological significance of the Ca2+ influx through slow muscle-type AChR on locomotor activity of zebrafish2023
- Author(s)
  Buntaro Zempo, Fumihito Ono, Koichi Nakajo
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Functional impact of the interaction between S1 segment and KCNE subunit in the modulation of KCNQ1 channels2023
- Author(s)
  Koichi Nakajo, Go Kasuya
- Organizer
  Biophysical 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] A role of the S1 segment in KCNQ1 modulation by KCNE2023
- Author(s)
  Koichi Nakajo, Go Kasuya
- Organizer
  Kv7 Channels Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Gating modulation of voltage-gated K+ channels by auxiliary subunits via voltage-sensing domains2023
- Author(s)
  Koichi Nakajo
- Organizer
  第100回日本生理学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Proper interaction between the S1 segment of KCNQ1 and KCNE3 is required for the constitutively open nature of the KCNQ1-KCNE3 K+ channel complex2023
- Author(s)
  Go Kasuya, Koichi Nakajo
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] The distinct biophysical properties and physiological roles of two zebrafish HCN4 pacemaker channels2023
- Author(s)
  Jiaying Liu, Go Kasuya, Buntaro Zempo & Koichi Nakajo
- Organizer
  The 10th Federation of the Asian and Oceanian Physiological Societies Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Gating Modulation of KCNQ1 Channels by KCNE Subunits: A Structure-guided Approach2023
- Author(s)
  Koichi Nakajo, Go Kasuya
- Organizer
  The 9th International Ion Channel Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Pharmacological properties and physiological roles of two zebrafish HCN4 channels2022
- Author(s)
  Jiaying Liu, Go Kasuya, Buntaro Zempo, Koichi Nakajo
- Organizer
  第99回日本生理学会年会
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Gating modulation by macromolecular complex formation in voltage-gated K+ channels2022
- Author(s)
  Koichi Nakajo
- Organizer
  第95回日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] Slow muscle type nicotinic acetylcholine receptor in zebrafish shows high Ca 2+ permeability2022
- Author(s)
  Buntaro Zempo, Fumihito Ono, Koichi Nakajo
- Organizer
  第99回日本生理学会年会
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] The proper distance between the S1 segment and KCNE3 is crucial for the constitutively open nature of the KCNQ1-KCNE3 K+ channel2022
- Author(s)
  Go Kasuya, Koich Nakajo
- Organizer
  第99回日本生理学会年会
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] 構造情報を基盤とした電位依存性イオンチャネル複合体の研究方法2022
- Author(s)
  中條浩一、糟谷豪
- Organizer
  第95回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06786
[Presentation] ゼブラフィッシュが持つ２つのHCN4チャネルの生物物理学的・薬理学的性質2021
- Author(s)
  劉嘉瑩、中條浩一
- Organizer
  第126回日本解剖学会第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-17K08552
[Presentation] ゼブラフィッシュの３つのROMKチャネルはそれぞれ異なる薬理学的性質を持つ2020
- Author(s)
  武田悠莉子、小野富三人、中條浩一
- Organizer
  第97回日本生理学会
- Data Source
  KAKENHI-PROJECT-17K08552
[Presentation] KCNEサブユニットによるKCNQ1電位センサードメインの制御機構2020
- Author(s)
  中條　浩一
- Organizer
  第97回日本生理学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08552
[Presentation] Determinants of Ba2+ sensitivity in zebrafish ROMK channels2019
- Author(s)
  Yuriko Takeda, Fumihito Ono, Koichi Nakajo
- Organizer
  9th FAOPS congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08552
[Presentation] The role of HCN4-positive cells in the gastrointestinal development and motility of zebrafish2019
- Author(s)
  Fujii Kensuke, Koichi Nakajo, Koichi Kawakami, Yoshihiro Egashira, Yasuhiro Yamamoto, Kohei Tanigushi, Masaru Kawai, Hideki Tomiyama, Kazuhisa Uchiyama, Fumihito Ono
- Organizer
  9th FAOPS congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08552
[Presentation] Zebrafish possesses three functional ROMK channels with different sensitivities to Ba2+2018
- Author(s)
  Yuriko Takeda, Fumihito Ono, Koichi Nakajo
- Organizer
  第95会日本生理学会（高松）
- Data Source
  KAKENHI-PROJECT-17K08552
[Presentation] Structural basis for the modulation of voltage sensor movement by auxiliary subunits in voltage-gated KCNQ1 channels2018
- Author(s)
  Koichi Nakajo
- Organizer
  第95会日本生理学会（高松）
- Data Source
  KAKENHI-PROJECT-17K08552
[Presentation] hERGチャネルの遅い脱活性化に関与するEAGドメイン、S4-S5リンカー、およびCリンカーの相互作用の解析2015
- Author(s)
  粂慎一郎、中條浩一、久保義弘
- Organizer
  第120回日本解剖学会総会・全国学術集会　第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県神戸市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-24590292
[Presentation] hERGチャネルの遅い脱活性化に関与するEAGドメイン、S4-S5リンカー、およびCリンカーの相互作用の解析2015
- Author(s)
  粂慎一郎、中條浩一、久保義弘
- Organizer
  第120回日本解剖学会総会・全国学術集会　第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県神戸市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PUBLICLY-25136724
[Presentation] QT短縮症候群を起こす変異を持ったKCNQ1チャネルの電位センサーの動きの変化2015
- Author(s)
  中條浩一、久保義弘
- Organizer
  第120回日本解剖学会総会・全国学術集会　第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県神戸市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-24590292
[Presentation] Kv4.2/DPP10複合体は4:2チャネルを形成しやすい2015
- Author(s)
  北沢和寛、中條浩一、久保義弘
- Organizer
  第120回日本解剖学会総会・全国学術集会　第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県神戸市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PUBLICLY-25136724
[Presentation] QT短縮症候群を起こす変異を持ったKCNQ1チャネルの電位センサーの動きの変化2015
- Author(s)
  中條浩一、久保義弘
- Organizer
  第120回日本解剖学会総会・全国学術集会　第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県神戸市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PUBLICLY-25136724
[Presentation] Kv4.2/DPP10複合体は4:2チャネルを形成しやすい2015
- Author(s)
  北沢和寛、中條浩一、久保義弘
- Organizer
  第120回日本解剖学会総会・全国学術集会　第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場・展示場（兵庫県神戸市）
- Year and Date
  2015-03-21
- Data Source
  KAKENHI-PROJECT-24590292
[Presentation] KCNQ1/KCNE1チャネルを開きにくくしている分子メカニズム2014
- Author(s)
  中條浩一、久保義弘
- Organizer
  中部日本生理学会
- Place of Presentation
  名古屋市立大学（愛知県名古屋市）
- Year and Date
  2014-11-08
- Data Source
  KAKENHI-PROJECT-24590292
[Presentation] KCNQ1/KCNE1チャネルを開きにくくしている分子メカニズム2014
- Author(s)
  中條浩一、久保義弘
- Organizer
  中部日本生理学会
- Place of Presentation
  名古屋市立大学(愛知県名古屋市）
- Year and Date
  2014-11-08
- Data Source
  KAKENHI-PUBLICLY-25136724
[Presentation] 哺乳類two-pore型カリウムチャネルTWIK-1の全反射赤外分光解析2013
- Author(s)
  塚本寿夫、中條浩一、久保義弘、古谷祐詞
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都国際会館(京都)
- Data Source
  KAKENHI-PROJECT-24650203
[Presentation] 電位センサードメインを介したKCNQチャネルのゲーティング修飾機構2013
- Author(s)
  中條浩一
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀(東京都)
- Year and Date
  2013-03-27
- Data Source
  KAKENHI-PUBLICLY-23136518
[Presentation] 哺乳動物カリウムチャネルの赤外分光解析2013
- Author(s)
  塚本寿夫、中條浩一、久保義弘、古谷祐詞
- Organizer
  平成24年度生物物理学会中部支部講演会
- Place of Presentation
  名古屋(名古屋大学)(口頭)
- Year and Date
  2013-02-19
- Data Source
  KAKENHI-PROJECT-24650203
[Presentation] 哺乳類two-pore型カリウムチャネルTWIK-1の全反射赤外分光解析2013
- Author(s)
  塚本寿夫、中條浩一、久保義弘、古谷祐詞
- Organizer
  第51回日本生物物理学会年会
- Place of Presentation
  京都(京都国際会議場)
- Data Source
  KAKENHI-PROJECT-24650203
[Presentation] 生物物理学的解析を目指した、哺乳培養細胞を用いた哺乳類カリウムイオンチャネルの大量発現の試み2012
- Author(s)
  塚本寿夫、中條浩一、久保義弘、古谷祐詞
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋(名古屋大学)(ポスター)
- Data Source
  KAKENHI-PROJECT-24650203
[Presentation] Ci-KCNQ1, an ortholog of vertebrate KCNQ1 from Ciona intestinalis, has revealed that KCNE1 and KCNE3 utilize different domains of KCNQ1 for the modulation of gating2012
- Author(s)
  Koichi Nakajo, Atsuo Nishino, Yasushi Okamura, Yoshihiro Kubo
- Organizer
  Biophysical Society 56th Annual Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-02-26
- Data Source
  KAKENHI-PUBLICLY-23136518
[Presentation] KCNE3によるゲーティング修飾におけるKCNQ1チャネルS1セグメントの機能的役割2012
- Author(s)
  中條浩一、西野敦雄、岡村康司、久保義弘
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館(長野県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PUBLICLY-23136518
[Presentation] KCNE3によるゲーティング修飾におけるKCNQ1チャネルS1セグメントの機能的役割2012
- Author(s)
  中條浩一、西野敦雄、岡村康司、久保義弘
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館(長野県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22790223
[Presentation] KCNE3によるゲーティング修飾におけるKCNQ1チャネルS1セグメントの機能的役割S 1 segment of KCNQ1 channel plays a critical role in gating modulation by KCNE32012
- Author(s)
  中條浩一、西野敦雄、岡村康司、久保義弘
- Organizer
  第89回日本生理学会大会
- Place of Presentation
  長野県松本文化会館(長野県)
- Year and Date
  2012-03-29
- Data Source
  KAKENHI-PROJECT-22790223
[Presentation] イオンチャネル修飾サブユニットの追加による生理機能進化2012
- Author(s)
  中條浩一
- Organizer
  第14回日本進化学会
- Place of Presentation
  首都大学東京(東京都)
- Year and Date
  2012-08-21
- Invited
- Data Source
  KAKENHI-PUBLICLY-23136518
[Presentation] Ci-KCNQ1, an ortholog of vertebrate KCNQ1 from Ciona intestinalis, has revealed that KCNE1 and KCNE3 utilize different domains of KCNQ1 for the modulation of gating2012
- Author(s)
  Koichi Nakajo, Atsuo Nishino, Yasushi Okamura, Yoshihiro Kubo
- Organizer
  Biophysical Society 56th Annual Meeting
- Place of Presentation
  San Diego, USA
- Year and Date
  2012-02-26
- Data Source
  KAKENHI-PROJECT-22790223
[Presentation] 生物物理学的解析を目指した、哺乳培養細胞を用いた哺乳類カリウムイオンチャネルの大量発現の試み2012
- Author(s)
  塚本寿夫、中條浩一、久保義弘、古谷祐詞
- Organizer
  第50回日本生物物理学会年会
- Place of Presentation
  名古屋大学（愛知県)
- Data Source
  KAKENHI-PROJECT-24650203
[Presentation] Ci-KCNQ1, an ortholog of vertebrate KCNQ1 from Ciona intestinalis, has revealed that KCNE1 and KCNE3 utilize different domains of KCNQ1 for the modulation of gating Biophysical Society2012
- Author(s)
  Koichi Nakajo, Atsuo Nishino, Yasushi Okamura and Yoshihiro Kubo
- Organizer
  56th Annual Meeting
- Place of Presentation
  San Diego Convention Center, San Diego, USA
- Year and Date
  2012-02-26
- Data Source
  KAKENHI-PROJECT-22790223
[Presentation] サブユニットカウンティング法によるKCNQ1-KCNE1イオンチャネル複合体ストイキオメトリーの発現依存的変化の解析Density-dependent changes of the stoichiometry of KCNQ1-KCNE1 ion channel complex revealed by direct subunit counting using single molecule imaging2011
- Author(s)
  中條浩一、Maximilian H. Ulbrich、久保義弘、Ehud Y. Isacoff
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22790223
[Presentation] サブユニットカウンティング法によるKCNQ1-KCNE1イオンチャネル複合体ストイキオメトリーの発現依存的変化の解析2011
- Author(s)
  中條浩一、Maximilian H.Ulbrich、久保義弘、Ehud Y.Isacoff
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PUBLICLY-23136518
[Presentation] Flexible stoichiometry and function of KCNQ1-KCNE1 ion channel complex2011
- Author(s)
  Nakajo K, Ulbrich MH, Kubo Y, Isacoff EY
- Organizer
  第88回日本生理学会/第116回日本解剖学会総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22790223
[Presentation] Ehud Y Isacoff KCNQ1-KCNE1イオンチャネル複合体の相対発現密度に依存するストイキオメトリーと機能のダイナミクス2011
- Author(s)
  中條浩一、Maximilian H Ulbrich、久保義弘
- Organizer
  第88回日本生理学会大会第116回日本解剖学会総会・全国学術集会合同大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-03-29
- Data Source
  KAKENHI-PROJECT-22790223
[Presentation] サブユニットカウンティング法によるKCNQ1-KCNE1イオンチャネル複合体ストイキオメトリーの発現依存的変化の解析2011
- Author(s)
  中條浩一、Maximilian H.Ulbrich、久保義弘、Ehud Y.Isacoff
- Organizer
  第34回日本神経科学大会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2011-09-15
- Data Source
  KAKENHI-PROJECT-22790223
[Presentation] Stoichiometry of KCNQ1-KCNE1 ion channel complex is flexible and density-dependent2010
- Author(s)
  Nakajo K, Ulbrich MH, Kubo Y, Isacoff EY
- Organizer
  Biophysical Society 54th Annual Meeting
- Place of Presentation
  モスコーンセンター(サンフランシスコ(米国))
- Year and Date
  2010-02-21
- Data Source
  KAKENHI-PROJECT-20790184
[Presentation] KCNEサブユニットによるKCNQ1チャネルのゲーティング修飾における電位センサードメインの役割2010
- Author(s)
  中條浩一、久保義弘
- Organizer
  第87回日本生理学会大会
- Place of Presentation
  盛岡市民文化ホール、いわて情報県民センター(岩手県)
- Year and Date
  2010-05-29
- Data Source
  KAKENHI-PROJECT-22790223
[Presentation] Stoichiometry of KCNQ1-KCNE1 ion channel complex is flexible and density dependent2010
- Author(s)
  Koichi Nakajo, Maximilian Ulbrich, Yoshihiro Kubo, Ehud Isacoff
- Organizer
  Biophysical Society 54th Annual Meeting
- Place of Presentation
  モスコーンセンター(サンフランシスコ、米国)
- Year and Date
  2010-02-21
- Data Source
  KAKENHI-PROJECT-20790184
[Presentation] KCNQ1チャネル複合体ストイキオメトリーの発現依存的変化2009
- Author(s)
  Koichi Nakajo, Maximilian Ulbrich, Yoshihiro Kubo, Ehud Isacoff
- Organizer
  日本生物物理学会第47回年会
- Place of Presentation
  アスティ徳島(徳島)
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20790184
[Presentation] KCNE1 modulates KCNQ1 through specific amino acid residues in the pore region2009
- Author(s)
  Koichi Nakajo, Atsuo Nishino, Yasushi Okamura, Yoshihiro Kubo
- Organizer
  国際生理学会IUPS2009
- Place of Presentation
  京都国際会議場(京都)
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20790184
[Presentation] KCNE1 modulates KCNQ1 through specific amino acid residues in the pore region2009
- Author(s)
  Nakajo K, Nishino A, Okamura Y, Kubo Y
- Organizer
  The 36^<th> congress of the international union of physiological sciences
- Place of Presentation
  京都国際会館(京都)
- Year and Date
  2009-07-29
- Data Source
  KAKENHI-PROJECT-20790184
[Presentation] KCNQ1チャネル複合体ストイキオメトリーの密度依存的変化2009
- Author(s)
  Nakajo K, Ulbrich MH, Kubo Y, Isacoff EY
- Organizer
  第47回生物物理学会年会
- Place of Presentation
  アスティとくしま(徳島)
- Year and Date
  2009-10-31
- Data Source
  KAKENHI-PROJECT-20790184
[Presentation] KCNE proteins stabilize voltage-sensing S4 segment of KCNQ1 channel2008
- Author(s)
  Koichi Nakajo, Yoshihiro Kubo
- Organizer
  Biophysical Society(USA)
- Place of Presentation
  ロングビーチ(米国)
- Year and Date
  2008-02-04
- Data Source
  KAKENHI-PROJECT-18790164
[Presentation] KCNQカリウムチャネル電位センサードメインのダイナミクスとその制御機構2008
- Author(s)
  中條浩一、久保義弘
- Organizer
  日本生物物理学会第46回年会
- Place of Presentation
  福岡国際会議場(福岡)
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20790184
[Presentation] KCNE1はKCNQ1の電位センサードメイン中のS1とS4の相互作用を阻害する2008
- Author(s)
  中條浩一、久保義弘
- Organizer
  日本生理学会
- Place of Presentation
  東京
- Year and Date
  2008-03-25
- Data Source
  KAKENHI-PROJECT-18790164
[Presentation] KCNQカリウムチャネル電位センサードメインのダイナミクスとその制御機構2008
- Author(s)
  中條浩一
- Organizer
  日本生物物理学会第46回年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-12-03
- Data Source
  KAKENHI-PROJECT-20790184
[Presentation] KCNQチャネルにおけるサブユニット認識および会合の機構2007
- Author(s)
  中條浩一、久保義弘
- Organizer
  日本神経科学学会
- Place of Presentation
  横浜
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-18790164
[Presentation] Dynamic aspects of the subunit stoichiometry of the KCNQ1/KCNE channel complex
- Author(s)
  Koichi Nakajo, Yoshihiro Kubo
- Organizer
  第37回国際生理学会議 (IUPS 2013)
- Place of Presentation
  Birmingham, UK
- Invited
- Data Source
  KAKENHI-PUBLICLY-25136724
[Presentation] A pair of phenylalanine residues on the S4 and S5 segments create a physical and energy barrier for the voltage sensor in KCNQ1/KCNE1 channel
- Author(s)
  Koichi Nakajo, Yoshihiro Kubo
- Organizer
  Biophysical Society 58th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PUBLICLY-25136724
[Presentation] 哺乳動物カリウムチャネルの赤外分光解析
- Author(s)
  塚本寿夫、中條浩一、久保義弘、古谷祐詞
- Organizer
  平成24年度　生物物理学会中部支部　講演会
- Place of Presentation
  名古屋大学（愛知県)
- Data Source
  KAKENHI-PROJECT-24650203
[Presentation] イオンチャネル修飾サブユニットの追加による生理機能進化
- Author(s)
  中條浩一
- Organizer
  第14回日本進化学会
- Place of Presentation
  首都大学東京（東京都）
- Invited
- Data Source
  KAKENHI-PROJECT-24590292
[Presentation] S4-S5 linkerとC-linker間の相互作用はhERGチャネルの遅い脱活性化を制御する
- Author(s)
  粂慎一郎、中條浩一、久保義弘
- Organizer
  第91回日本生理学会
- Place of Presentation
  鹿児島大学(鹿児島県)
- Data Source
  KAKENHI-PUBLICLY-25136724
[Presentation] S4およびS5セグメントのフェニルアラニン残基がつくる電位センサードメインに対する物理的な障壁がKCNQ1/KCNE1チャネルのゲーティングを遅くする
- Author(s)
  中條浩一、久保義弘
- Organizer
  第91回日本生理学会
- Place of Presentation
  鹿児島大学（鹿児島）
- Data Source
  KAKENHI-PROJECT-24590292
[Presentation] 電位センサードメインを介したKCNQチャネルのゲーティング修飾機構
- Author(s)
  中條浩一、久保義弘
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  タワーホール船堀（東京都）
- Data Source
  KAKENHI-PROJECT-24590292
[Presentation] S4およびS5セグメントのフェニルアラニン残基がつくる電位センサードメインに対する物理的な障壁がKCNQ1/KCNE1チャネルのゲーティングを遅くする
- Author(s)
  中條浩一、久保義弘
- Organizer
  第91回日本生理学会
- Place of Presentation
  鹿児島大学(鹿児島県)
- Data Source
  KAKENHI-PUBLICLY-25136724
[Presentation] Kv4イオンチャネル複合体のストイキオメトリーと機能はKChIPの発現量依存的に変化する
- Author(s)
  北沢和寛、中條浩一、久保義弘
- Organizer
  第91回日本生理学会
- Place of Presentation
  鹿児島大学(鹿児島県)
- Data Source
  KAKENHI-PUBLICLY-25136724
[Presentation] A pair of phenylalanine residues on the S4 and S5 segments create a physical and energy barrier for the voltage sensor in KCNQ1/KCNE1 channel
- Author(s)
  Koichi Nakajo, Yoshihiro Kubo
- Organizer
  Biophysical Society 58th Annual Meeting
- Place of Presentation
  San Francisco, USA
- Data Source
  KAKENHI-PROJECT-24590292
[Presentation] Dynamic aspects of the subunit stoichiometry of the KCNQ1/KCNE channel complex
- Author(s)
  Koichi Nakajo, Yoshihiro Kubo
- Organizer
  第37回国際生理学会議(IUPS2013)
- Place of Presentation
  Birmingham, UK
- Invited
- Data Source
  KAKENHI-PROJECT-24590292

1. FURUTANI Yuji (80432285)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. TSUKAMOTO Hisao (90579814)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. KIMURA Tetsunari (70506906)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KUBO Yoshihiro (80211887)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
5. MICHIHIRO TATEYAMA (30276472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 東雅大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 木瀬孔明

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 岡村孝司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakajo Koichi 中條 浩一

NAKAJO Koichi 中條 浩一

Research Projects

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Understanding of the Kv/HCN channel gating mechanism based on structural informationPrincipal Investigator

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Detection of molecular configuration of ion channel complexes in vivo and elucidation of their physiological functionsPrincipal Investigator

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Functional analysis of auxiliary subunits of KCNQ1 channels in the heartPrincipal Investigator

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Analysis of the voltage dependence of Gq coupled receptors

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ストイキオメトリーの違いを考慮したＫＣＮＱ１チャネル活性化機構の光生理学的解析Principal Investigator

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Stoichiometry and current kinetics of KCNQ1-KCNE1 ion channel complexPrincipal Investigator

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Functional expression of mammalian ion channels and analysis of the molecular mechanisms

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ストイキオメトリーの多様性を考慮に入れた新しい心筋カリウムチャネルモデルの確立Principal Investigator

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Detection of state-dependent change of the stoichiometry of KCNQ1-KCNE1 complex by single molecule imagingPrincipal Investigator

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Mechanisms of KCNQ1 channel modulation by KCNE proteins revealed by ascidian KCNQ1 homologuePrincipal Investigator

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KCNQ1チャネルのKCNE1会合による活性化遅延機構の電気・光生理学的解析Principal Investigator

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[Journal Article] Modulation of potassium channels by transmembrane auxiliary subunits via voltage‐sensing domains2024

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[Journal Article] History and outlook of voltage-gated potassium channel research2023

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Nakajo Koichi 中條浩一

NAKAJO Koichi 中條浩一