Watanabe Satoshi 渡部聡

… Alternative Names

渡部聡ワタナベサトシ

WATANABE Satoshi 渡部聡

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Researcher Number	80391572
Other IDs
Affiliation (Current)	2025: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門, グループ長補佐
Affiliation (based on the past Project Information) *help	2025: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門, グループ長補佐 2023: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門, 上級研究員 2020: 国立研究開発法人農業・食品産業技術総合研究機構, 畜産研究部門, 上級研究員 2015: 国立研究開発法人農業生物資源研究所, ゲノム研究センター・家畜ゲノム, 主任研究員 2014: 独立行政法人農業生物資源研究所, その他部局等, 主任研究員 … More 2014: 独立行政法人農業生物資源研究所, その他部局等, 研究員 2013: 独立行政法人農業生物資源研究所, 畜産ゲノム研究ユニット, 主任研究員 2012: 独立行政法人農業生物資源研究所, ゲノム研究センター・家畜ゲノム, 主任研究員 2011: 農業生物資源研究所, 動物科学家畜ゲノム, 主任研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / 0605:Veterinary medical science, animal science, and related fields / Basic Section 42020:Veterinary medical science-related / Integrative animal science Except Principal Investigator Morphological basic dentistry
Keywords	Principal Investigator ゲノム編集 / ウシ / 地球温暖化 / 体毛周期 / プロラクチン受容体 / 耐暑性向上 / 遺伝子改変ブタ / 抗病性 / CRISPR/Cas9 / アデノ随伴ウイルスベクター / 細胞選択法 / target toxin / EndoGalC … More Except Principal Investigator … More Tbx1 / Sez12 / Dgcr2 / 顎形態形成 / ノックアウトマウス / 22q11.2欠失症候群 / BMP / BMPシグナル / TGF-βシグナル / 軟骨細胞分化 / ノックインGFP / 顎顔面骨格形成 / TGF-beta / 頭蓋底軟骨結合 / DGCR2 / Neural crest cell / CT / 鼻中隔 / 関節軟骨 / GFP / 軟骨内骨化 / 22q11欠失症候群 / Sez12遺伝子 Less

エピゾーマルベクターによる牛幹細胞の新規ゲノム編集系の開発と応用Principal Investigator
- Principal Investigator
  
  渡部聡
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  National Agriculture and Food Research Organization
独自開発のゲノム編集法を用いた地球温暖化対応の耐暑性ウシの作成Principal Investigator
- Principal Investigator
  
  渡部聡
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0605:Veterinary medical science, animal science, and related fields
- Research Institution
  National Agriculture and Food Research Organization
Efficient production of CD46 knockout pigs by using adeno-associated virus vectors carrying the CRISPR / Cas9 systemPrincipal Investigator
- Principal Investigator
  
  渡部聡
- Project Period (FY)
  2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  National Agriculture and Food Research Organization
ブタ脂肪前駆細胞におけるゲノム編集を用いた細胞分化制御メカニズムの解析Principal Investigator
- Principal Investigator
  
  渡部聡
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Integrative animal science
- Research Institution
  National Institute of Agrobiological Sciences
Sez12 gene contributes to the chondrocytes differentiation by modulating TGF-ß signaling during postnatal maxillofacial development.
- Principal Investigator
  
  KAJIWARA Kagemasa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokai University
Molecular analysis of craio-facial abnormalities found in the Sez12 knockout mice
- Principal Investigator
  
  KAJIWARA Kagemasa
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Tokai University

All 2023 2020 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] Recent Advances in In Vivo Somatic Cell Gene Modification in Newborn Pups2023
- Author(s)
  Nakamura Shingo、Morohoshi Kazunori、Inada Emi、Sato Yoko、Watanabe Satoshi、Saitoh Issei、Sato Masahiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 20 Pages: 15301-15301
- DOI
  10.3390/ijms242015301
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19334, KAKENHI-PROJECT-23KJ2200, KAKENHI-PROJECT-23K09441, KAKENHI-PROJECT-21K10165, KAKENHI-PROJECT-22K16888, KAKENHI-PROJECT-23K27097
[Journal Article] Recent Advances in the Production of Genome-Edited Animals Using <i>i</i>-GONAD, a Novel <i>in vivo</i> Genome Editing System, and Its Possible Use for the Study of Female Reproductive Systems2023
- Author(s)
  Sato Masahiro、Morohoshi Kazunori、Ohtsuka Masato、Takabayashi Shuji、Inada Emi、Saitoh Issei、Watanabe Satoshi、Nakamura Shingo
- Journal Title
  
  OBM Genetics
  
  Volume: 07 Issue: 04 Pages: 1-30
- DOI
  10.21926/obm.genet.2304207
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K19334, KAKENHI-PROJECT-23KJ2200, KAKENHI-PROJECT-23K09441, KAKENHI-PROJECT-21K10165, KAKENHI-PROJECT-22K16888, KAKENHI-PROJECT-23K27097
[Journal Article] Hydrodynamics-based transplacental delivery as a useful noninvasive tool for manipulating fetal genome2020
- Author(s)
  Nakamura　S, Ando N, Watanabe S, Akasaka E, Ishihara M, Sato M
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 7 Pages: 1744-1744
- DOI
  10.3390/cells9071744
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06372, KAKENHI-PROJECT-19H03152, KAKENHI-PROJECT-20K06440
[Journal Article] Abnormal gait, reduced locomotor activity and impaired motor coordination in Dgcr2-deficient mice2016
- Author(s)
  Shin-ichiro Mugikura, Akira Katoh, Satoshi Watanabe, MinoruKimura, and KagemasaKajiwara
- Journal Title
  
  Biochemistory and Biophysics Reports
  
  Volume: 5 Pages: 120-126
- DOI
  10.1016/j.bbrep.2015.11.015
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25462876
[Journal Article] A non-inheritable maternal Cas9-based multiple-gene editing system in mice2016
- Author(s)
  Sakurai T, Kamiyoshi A, Kawate H, Mori C, Watanabe S, Tanaka M, Uetake R, Sato M, Shindo T.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 20011-20011
- DOI
  10.1038/srep20011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25460330, KAKENHI-PROJECT-26670153, KAKENHI-PROJECT-26293085, KAKENHI-PROJECT-26293183, KAKENHI-PROJECT-26450454, KAKENHI-PROJECT-15K07695
[Journal Article] A combination of targeted toxin technology and the piggyBac-mediated gene transfer system enables efficient isolation of stable transfectants in nonhuman mammalian cells2015
- Author(s)
  Sato M, Inada E, Saitoh I, Matsumoto Y, Ohtsuka M, Miura H, Nakamura S, Sakurai T, Watanabe S
- Journal Title
  
  Biotechnolgy Journal
  
  Volume: 10 Issue: 1 Pages: 143-153
- DOI
  10.1002/biot.201400283
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24580411, KAKENHI-PROJECT-25463192, KAKENHI-PROJECT-26670883, KAKENHI-PROJECT-26670153, KAKENHI-PROJECT-26293085, KAKENHI-PROJECT-26450454
[Journal Article] Direct injection of CRISPR/Cas9-related mRNA into cytoplasm of parthenogenetically activated porcine oocytes causes frequent mosaicism for indel mutations.2015
- Author(s)
  Sato M, Koriyama M, Watanabe S, Ohtsuka M, Sakurai T, Inada E, Saitoh I, Nakamura S, Miyoshi K
- Journal Title
  
  International Journal of Molecular Sciences,
  
  Volume: 16 Issue: 8 Pages: 17838-17856
- DOI
  10.3390/ijms160817838
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07695, KAKENHI-PROJECT-25463192, KAKENHI-PROJECT-25450475, KAKENHI-PROJECT-26670153, KAKENHI-PROJECT-25850226, KAKENHI-PROJECT-26293085, KAKENHI-PROJECT-26450454
[Journal Article] Generation of α-1,3-galactosyltransferase-deficient porcine embryonic fibroblasts by CRISPR/Cas9-mediated knock-in of a small mutated sequence and a targeted toxin-based selection system.2015
- Author(s)
  Sato M, Kagoshima A, Saitoh I, Inada E, Miyoshi K, Ohtsuka M, Nakamura S, Sakurai T, Watanabe S
- Journal Title
  
  Domestic Animal Reproduction
  
  Volume: 50 Issue: 5 Pages: 872-880
- DOI
  10.1111/rda.12565
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K07695, KAKENHI-PROJECT-15K11362, KAKENHI-PROJECT-25463192, KAKENHI-PROJECT-25450475, KAKENHI-PROJECT-26670153, KAKENHI-PROJECT-25850226, KAKENHI-PROJECT-25293418, KAKENHI-PROJECT-26293085, KAKENHI-PROJECT-26450454
[Journal Article] Novel cancer vaccination system based on human endo-β-N-Acetyl glucosaminidase gene delivery2014
- Author(s)
  Watanabe S, Haraguchi S, Nakamura S, Sakurai T, Mugikura S, Kajiwara K, Minoiru K, Sato M
- Journal Title
  
  Journal of Glycobiology
  
  Volume: 3 Issue: 01 Pages: 1-1
- DOI
  10.4172/2168-958x.1000106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23593038, KAKENHI-PROJECT-23700562, KAKENHI-PROJECT-24580411, KAKENHI-PROJECT-25462876
[Journal Article] In vivo gene transfer in mouse preimplantation embryos after intraoviductal injection of plasmid DNA and subsequent in vivo electroporation2012
- Author(s)
  Masahiro Sato, Eri Akasaka, Issei Saitoh, Masato Ohtsuka and Satoshi Watanabe
- Journal Title
  
  Systems Biol. in Reprod. Med
  
  Pages: 1-10
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] Improvement of a phiC31 integrase-based gene delivery system that confers high and continuous transgene expression2011
- Author(s)
  Satoshi Watanabe, (他4名)
- Journal Title
  
  New Biotechnology
  
  Volume: 28(4) Pages: 312-319
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Journal Article] A novel glycosylation signal regulates transforming growth factor β receptors as evidenced by endo-β-galactosidase C expression in rodent cells2011
- Author(s)
  Satoshi Watanabe, (他5名)
- Journal Title
  
  Glycobiology
  
  Volume: 21(4) Pages: 482-492
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] マウスDgcr2遺伝子はTGF-βシグナルを介して分化軟骨細胞の増殖を制御する2015
- Author(s)
  梶原景正, 青山謙一, 内堀雅博, 清陸王, 渡部聡, 木村穣
- Organizer
  第３８回日本分子生物学会年会・第８８回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] EndGalCとIB4-SAPの組み合わせを用いたCRISPR遺伝子による遺伝子改変細胞濃縮法の開発2014
- Author(s)
  渡部　聡、桜井敬之、中村伸吾、梶原景正、木村　穣、佐藤正宏
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-26450454
[Presentation] 22q11.2欠失症候群で欠失するヒトDGCR2遺伝子のマウスホモログDgcr2のTGF-βシグナルへの影響2013
- Author(s)
  梶原景正、麥倉信一郎、渡部聡、木村穣
- Organizer
  日本生化学会大会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] 22q11.2欠失症候群で欠失するヒトDGCR2遺伝子のTGF-β/BMPシグナルとの相互作用2013
- Author(s)
  梶原景正、麥倉信一郎、渡部聡、木村穣
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] The Sez12, Coding the C-type Lectin-like Domain-containing Membrane Protein, Plays a Regulatory Role in T Cell Growth2012
- Author(s)
  S. Mugikura, S. Watanabe, K.Kajiwara, M.Kimura
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] Sez12, the Murine Homolog of DGCR2 Gene Laid within the Microdeletion of 22q11.2 Deletion Syndrome, Functions in the Endochondral Ossification2012
- Author(s)
  K.Kajiwara, S. Mugikura, S. Watanabe, M.Kimura
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] Sez12遺伝子欠失マウスの免疫系細胞における細胞増殖能の検討2011
- Author(s)
  麥倉信一郎、千葉朋希、渡部聡、梶原景正、木村穣
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  神奈川
- Data Source
  KAKENHI-PROJECT-22592050
[Presentation] EndoGalCとtargeted toxin法の組み合わせを用いたCRISPR系でノックアウトされた遺伝子改変細胞濃縮法の開発
- Author(s)
  渡部聡、桜井敬之、中村伸吾、梶原景正、木村穣、佐藤正宏
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25462876
[Presentation] マウスDgcr２遺伝子は軟骨細胞の増殖分化制御により骨格形成に影響を与える
- Author(s)
  梶原景正、渡部聡、木村穰
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25462876

1. KIMURA Minoru (10146706)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. KAJIWARA Kagemasa (00204397)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
3. 石井和雄 (80414697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. KAMIYOSHI Akiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 佐藤正宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
6. 三好和睦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Watanabe Satoshi 渡部 聡

渡部 聡 ワタナベ サトシ

WATANABE Satoshi 渡部 聡

Research Projects

Research Products

Co-Researchers

エピゾーマルベクターによる牛幹細胞の新規ゲノム編集系の開発と応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

独自開発のゲノム編集法を用いた地球温暖化対応の耐暑性ウシの作成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Efficient production of CD46 knockout pigs by using adeno-associated virus vectors carrying the CRISPR / Cas9 systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ブタ脂肪前駆細胞におけるゲノム編集を用いた細胞分化制御メカニズムの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sez12 gene contributes to the chondrocytes differentiation by modulating TGF-&#223; signaling during postnatal maxillofacial development.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of craio-facial abnormalities found in the Sez12 knockout mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Recent Advances in In Vivo Somatic Cell Gene Modification in Newborn Pups2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Recent Advances in the Production of Genome-Edited Animals Using &lt;i&gt;i&lt;/i&gt;-GONAD, a Novel &lt;i&gt;in vivo&lt;/i&gt; Genome Editing System, and Its Possible Use for the Study of Female Reproductive Systems2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hydrodynamics-based transplacental delivery as a useful noninvasive tool for manipulating fetal genome2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Abnormal gait, reduced locomotor activity and impaired motor coordination in Dgcr2-deficient mice2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A non-inheritable maternal Cas9-based multiple-gene editing system in mice2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A combination of targeted toxin technology and the piggyBac-mediated gene transfer system enables efficient isolation of stable transfectants in nonhuman mammalian cells2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Direct injection of CRISPR/Cas9-related mRNA into cytoplasm of parthenogenetically activated porcine oocytes causes frequent mosaicism for indel mutations.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of α-1,3-galactosyltransferase-deficient porcine embryonic fibroblasts by CRISPR/Cas9-mediated knock-in of a small mutated sequence and a targeted toxin-based selection system.2015

Author(s)

Journal Title

Watanabe Satoshi 渡部聡

渡部聡ワタナベサトシ

WATANABE Satoshi 渡部聡

Sez12 gene contributes to the chondrocytes differentiation by modulating TGF-ß signaling during postnatal maxillofacial development.

[Journal Article] Recent Advances in the Production of Genome-Edited Animals Using <i>i</i>-GONAD, a Novel <i>in vivo</i> Genome Editing System, and Its Possible Use for the Study of Female Reproductive Systems2023