NAKAHASHI RIKA 中橋理佳

… Alternative Names

Nakahashi Rika 中橋理佳

Ouchida Rika 大内田理佳

OUCHIDA Rika 大内田理佳

大内田理佳オオウチダリカ

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Researcher Number	80391887
Other IDs
Affiliation (Current)	2025: 千葉大学, 医学部附属病院, 特任准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 千葉大学, 医学部附属病院, 特任准教授 2018 – 2021: 東京大学, 医科学研究所, 特任講師 2016 – 2017: 東京大学, 医科学研究所, 助教 2015: 東京大学, 医科学研究所, 特任研究員 2014: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員 2008 – 2012: The Institute of Physical and Chemical Research, 免疫多様性研究チーム, 研究員 2005 – 2006: 独立行政法人理化学研究所, 免疫多様性研究チーム, 研究員
Review Section/Research Field	Principal Investigator Immunology / Bacteriology (including mycology) / Basic Section 53030:Respiratory medicine-related / Neurochemistry/Neuropharmacology Except Principal Investigator Immunology / Basic Section 57020:Oral pathobiological science-related / Studies on the Super-Aging Society / Biological Sciences
Keywords	Principal Investigator ドラッグデリバリーシステム / カチオン化ナノゲル / 粘膜免疫応答 / 経鼻ワクチン / 自己免疫疾患 / リソソーム / 感染症 / 結核ワクチン / 慢性閉塞性肺疾患 / IgG抗体の受容体 … More / IgG抗体受容体 / 母体由来IgG抗体 / 貪食 / Fcγ受容体 / IgG抗体 / ミクログリア / B cell receptor (BCR) / B cell activation / lysosome / B cell receptor(BCR) / B細胞活性化 / B細胞抗原受容体 / T細胞抗原受容体(TCR) / T細胞活性化 / T細胞抗原受容体 … More Except Principal Investigator 粘膜免疫 / 分泌型IgA / アジュバント / 老化 / ミスマッチ修復 / DNAポリメラーゼ / 体細胞変異 / 唾液IgA抗体 / 動脈硬化 / 粘膜ワクチン / 抗原特異的IgA / 歯槽骨吸収 / サイトカイン / 高原特異的IgA / 歯周病 / 舌下ワクチン / ワクチン / ダブルシグナル / メモリー免疫応答 / 肺炎球菌 / Foxp1 / Flt3リガンド / CpG ODN / 粘膜IgA / 記憶免疫 / IgG受容体 / 液性免疫 / Bリンパ球 / IgM受容体 / Humoral immunity / B lymphocyte / IgM Fc receptor / DNA修復 / DNA polymerase η / Uracil DNA glycosylase / 胚中心Ｂ細胞 / 細胞分裂 / 抗体遺伝子 / 胚中心B細胞 / affinity maturation / uracil-DNA glycosylase / abasic site / activation-induced cytidine deaminase / low fidelity DNA polymerase / immunoglobulin gene / somatic hypermutation / 遺伝子改変マウス / DNA損傷修復 / 高親和性抗体 / 免疫グロブリン遺伝子 Less

Development of an intranasal vaccine to prevent respiratory infections that cause exacerbations of chronic obstructive pulmonary disease.Principal Investigator
- Principal Investigator
  
  Nakahashi Rika
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53030:Respiratory medicine-related
- Research Institution
  Chiba University
  The University of Tokyo
抗原非依存型ダブルシグナルシステムによる老化粘膜免疫の再生
- Principal Investigator
  
  Fujihashi Kohtaro
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  Chiba University
  The University of Tokyo
Rejuvenation of mucosal immunosenescence by the sublingual vaccine: The prevention and treatment for periodontal disease and arteriosclerosis
- Principal Investigator
  
  Fujihashi Kohtaro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Chiba University
  The University of Tokyo
Basic research for the TB vaccine development based on the novel drug delivery system.Principal Investigator
- Principal Investigator
  
  Nakahashi Rika
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  The University of Tokyo
Role of microglia on brain development through maternal IgG-Fcgamma receptor pathway.Principal Investigator
- Principal Investigator
  
  OUCHIDA Rika
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  The University of Tokyo
  The Institute of Physical and Chemical Research
Role of IgM Fc receptor in enhancing humoral immune responses and preventing autoimmunity
- Principal Investigator
  
  Wang Ji-Yang
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  Tokyo Medical and Dental University
Mechanisms of the induction of A:T mutations in the germinal center B cells
- Principal Investigator
  
  WANG Jiyang
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Analysis of BCR degradation by a lysosomal protein LAPTM5Principal Investigator
- Principal Investigator
  
  OUCHIDA Rika
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Analysis of TCR regulation by a lysosomal protein LAPTM5Principal Investigator
- Principal Investigator
  
  OUCHIDA Rika
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  The Institute of Physical and Chemical Research
Bリンパ球の生存、増殖及びゲノム変異に果すDNAポリメラーゼシータの役割の解明
- Principal Investigator
  
  WANG Jiyang
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The Institute of Physical and Chemical Research

[Journal Article] MucoRice-CTB line 19A, a new marker-free transgenic rice-based cholera vaccine produced in an LED-based hydroponic system2024
- Author(s)
  Yuki Yoshikazu、Kurokawa Shiho、Sugiura Kotomi、Kashima Koji、Maruyama Shinichi、Yamanoue Tomoyuki、Honma Ayaka、Mejima Mio、Takeyama Natsumi、Kuroda Masaharu、Kozuka-Hata Hiroko、Oyama Masaaki、Masumura Takehiro、Nakahashi-Ouchida Rika、Fujihashi Kohtaro、Hiraizumi Takashi、Goto Eiji、Kiyono Hiroshi
- Journal Title
  
  Frontiers in Plant Science
  
  Volume: 15 Pages: 1342662-1342662
- DOI
  10.3389/fpls.2024.1342662
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20495, KAKENHI-PLANNED-21H05280
[Journal Article] Glycoprotein 2 as a gut gate keeper for mucosal equilibrium between inflammation and immunity.2023
- Author(s)
  3.Zhang Z., Tanaka I., Nakahashi-Ouchida R., Ernst P, Kiyono H., Kurashima Y.
- Journal Title
  
  Seminars in immunopathology
  
  Volume: - Issue: 4-6 Pages: 493-507
- DOI
  10.1007/s00281-023-00999-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08514
[Journal Article] Cationic-nanogel nasal vaccine containing the ectodomain of RSV-small hydrophobic protein induces protective immunity in rodents2023
- Author(s)
  Umemoto S、Nakahashi-Ouchida R、Yuki Y、Kurokawa S、Machita T、Uchida Y、Mori H、Yamanoue T、Shibata T、Sawada S、Ishige K、Hirano T、Fujihashi K、Akiyoshi Ki、Kurashima Y、Tokuhara D、Ernst PB、Suzuki M、Kiyono H
- Journal Title
  
  npj Vaccines
  
  Volume: 8 Issue: 1 Pages: 106-106
- DOI
  10.1038/s41541-023-00700-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20495, KAKENHI-PROJECT-20K08514
[Journal Article] Biodistribution assessment of cationic pullulan nanogel, a nasal vaccine delivery system, in mice and non-human primates2023
- Author(s)
  Yuki Yoshikazu、Harada Norihiro、Sawada Shin-ichi、Uchida Yohei、Nakahashi-Ouchida Rika、Mori Hiromi、Yamanoue Tomoyuki、Machita Tomonori、Kanazawa Masakatsu、Fukumoto Dai、Ohba Hiroyuki、Miyazaki Takashi、Akiyoshi Kazunari、Fujihashi Kohtaro、Kiyono Hiroshi
- Journal Title
  
  Vaccine
  
  Volume: 41 Issue: 34 Pages: 4941-4949
- DOI
  10.1016/j.vaccine.2023.06.065
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20495, KAKENHI-PROJECT-20K08514
[Journal Article] Nasal vaccines: solutions for respiratory infectious diseases2023
- Author(s)
  Nakahashi-Ouchida Rika、Fujihashi Kohtaro、Kurashima Yosuke、Yuki Yoshikazu、Kiyono Hiroshi
- Journal Title
  
  Trends in Molecular Medicine
  
  Volume: 29 Issue: 2 Pages: 124-140
- DOI
  10.1016/j.molmed.2022.10.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20495, KAKENHI-PROJECT-20H03856, KAKENHI-PROJECT-18H05280, KAKENHI-PROJECT-21K19494, KAKENHI-PROJECT-18KK0432
[Journal Article] Oral MucoRice-CTB vaccine is safe and immunogenic in healthy US adults2022
- Author(s)
  Yuki Yoshikazu、Nojima Masanori、Kashima Koji、Sugiura Kotomi、Maruyama Shinichi、Kurokawa Shiho、Yamanoue Tomoyuki、Nakahashi-Ouchida Rika、Nakajima Hiroyuki、Hiraizumi Takashi、Kohno Hitoshi、Goto Eiji、Fujihashi Kohtaro、Kiyono Hiroshi
- Journal Title
  
  Vaccine
  
  Volume: 40 Issue: 24 Pages: 3372-3379
- DOI
  10.1016/j.vaccine.2022.04.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03856, KAKENHI-PROJECT-18H05280
[Journal Article] Induction of Mucosal IgA?Mediated Protective Immunity Against Nontypeable Haemophilus influenzae Infection by a Cationic Nanogel?Based P6 Nasal Vaccine2022
- Author(s)
  Nakahashi-Ouchida Rika、Mori Hiromi、Yuki Yoshikazu、Umemoto Shingo、Hirano Takashi、Uchida Yohei、Machita Tomonori、Yamanoue Tomoyuki、Sawada Shin-ichi、Suzuki Masashi、Fujihashi Kohtaro、Akiyoshi Kazunari、Kurono Yuichi、Kiyono Hiroshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13
- DOI
  10.3389/fimmu.2022.819859
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K20495, KAKENHI-PROJECT-20H03856
[Journal Article] Development of Antibody-Fragment?Producing Rice for Neutralization of Human Norovirus2021
- Author(s)
  Sasou Ai、Yuki Yoshikazu、Kurokawa Shiho、Sato Shintaro、Goda Yuki、Uchida Masao、Matsumoto Naomi、Sagara Hiroshi、Watanabe Yuji、Kuroda Masaharu、Sakon Naomi、Sugiura Kotomi、Nakahashi-Ouchida Rika、Ushijima Hiroshi、Fujihashi Kohtaro、Kiyono Hiroshi
- Journal Title
  
  Frontiers in Plant Science
  
  Volume: 12 Pages: 639953-639953
- DOI
  10.3389/fpls.2021.639953
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20495, KAKENHI-PROJECT-19H03702, KAKENHI-PROJECT-20H03856, KAKENHI-PROJECT-19K22532
[Journal Article] Mucosal vaccines: wisdom from now and then2021
- Author(s)
  Kiyono Hiroshi、Yuki Yoshikazu、Nakahashi-Ouchida Rika、Fujihashi Kohtaro
- Journal Title
  
  International Immunology
  
  Volume: 33 Issue: 12 Pages: 767-774
- DOI
  10.1093/intimm/dxab056
- Open Access
- Data Source
  KAKENHI-PROJECT-20H03856, KAKENHI-PROJECT-20K20495
[Journal Article] Nanogel-based nasal vaccines for infectious and lifestyle-related diseases.2019
- Author(s)
  Azegami T, Yuki Y, Nakahashi R, Itoh H, Kiyono H.
- Journal Title
  
  Molecular Immunology
  
  Volume: 98 Pages: 19-24
- DOI
  10.1016/j.molimm.2017.10.022
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08821
[Journal Article] A role for the CCR5?CCL5 interaction in the preferential migration of HSV-2-specific effector cells to the vaginal mucosa upon nasal immunization2019
- Author(s)
  Joo Sunyi、Suwanto Aldina、Sato Ayuko、Nakahashi-Ouchida Rika、Mori Hiromi、Uchida Yohei、Sato Shintaro、Kurashima Yosuke、Yuki Yoshikazu、Fujihashi Kohtaro、Kawaguchi Yasushi、Kiyono Hiroshi
- Journal Title
  
  Mucosal Immunology
  
  Volume: 12 Issue: 6 Pages: 1391-1403
- DOI
  10.1038/s41385-019-0203-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22524, KAKENHI-PROJECT-19K22532, KAKENHI-PROJECT-19K22634, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06433, KAKENHI-PROJECT-19H03702, KAKENHI-PROJECT-17H04080, KAKENHI-PROJECT-18KK0432, KAKENHI-PROJECT-18H05280, KAKENHI-PROJECT-19H03450, KAKENHI-PROJECT-17K08821
[Journal Article] ナノゲルデリバリーシステムによる肺炎球菌経鼻ワクチンの開発2019
- Author(s)
  中橋理佳、幸義和、清野宏
- Journal Title
  
  炎症と免疫
  
  Volume: 27 Pages: 19-24
- Data Source
  KAKENHI-PROJECT-17K08821
[Journal Article] Cationic pullulan nanogel as a safe and effective nasal vaccine delivery system for respiratory infectious diseases.2018
- Author(s)
  Nakahashi-Ouchida R., Yuki Y., Kiyono H.
- Journal Title
  
  Human Vaccines & Immunotherapeutics
  
  Volume: 14 Issue: 12 Pages: 2189-2193
- DOI
  10.1080/14760584.2017.1395702
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08821
[Journal Article] 粘膜ワクチンの潮流と課題2018
- Author(s)
  西村潤、中橋理佳、幸義和、清野宏
- Journal Title
  
  医学のあゆみ
  
  Volume: 264 Pages: 18227-18234
- Data Source
  KAKENHI-PROJECT-17K08821
[Journal Article] LAPTM5 promotes lysosomal degradation of intracellular but not the cell surface CD3ζimmunol..2014
- Author(s)
  Kawai, Y., Ouchida, R., Yamasaki, S., Dragone, L., Tsubata, T. and Wang, J.-Y.
- Journal Title
  
  Cell Biol.
  
  Volume: 92 Issue: 6 Pages: 527-534
- DOI
  10.1038/icb.2014.18
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390063, KAKENHI-PROJECT-25460604, KAKENHI-PLANNED-26110009, KAKENHI-PROJECT-26293062, KAKENHI-PROJECT-26293099, KAKENHI-PROJECT-26670213
[Journal Article] FcmR interacts and cooperates with the B cell receptor to promote B cell survival.2014
- Author(s)
  Ouchida. R., Lu. Q., Liu. J., Li. Y., Chu. Y., Tsubata. T. and Wang, J.Y.
- Journal Title
  
  J. Immunol.
  
  Volume: 194 Issue: 7 Pages: 3096-4101
- DOI
  10.4049/jimmunol.1402352
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-23390063, KAKENHI-PROJECT-25460604, KAKENHI-PROJECT-26293062
[Journal Article] Complement-activating IgM enhances the humoral but not the T cell immune response in mice2013
- Author(s)
  Ding, Z., Bergman, A., Rutemark, C., Ouchida, R., Ohno, H., Wang, J.-Y. and Heyman, B.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 11 Pages: e81299-e81299
- DOI
  10.1371/journal.pone.0081299
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460604
[Journal Article] FcμR (Toso/Faim3) is not an inhibitor of Fas-mediated cell death in mouse T and B cells2013
- Author(s)
  Ouchida, R., Mori, H., Ohno, H. and Wang, J.-Y.
- Journal Title
  
  Blood
  
  Volume: 121 Issue: 12 Pages: 2368-2370
- DOI
  10.1182/blood-2012-12-470906
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590445, KAKENHI-PROJECT-25460604
[Journal Article] Critical role of the IgM Fc receptor in IgM homeostasis, B cell survival and humoral immune responses2012
- Author(s)
  Ouchida, R., Mori, H., Hase, K., Takatsu, H., Kurosaki, T., Tokuhisa, T., Ohno, H., Wang. J. -Y.
- Journal Title
  
  Proc. Natl. Acad. Sci. USA
  
  Volume: 109 Issue: 40 Pages: 2699-2706
- DOI
  10.1073/pnas.1210706109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12F02784, KAKENHI-PROJECT-21229007, KAKENHI-PROJECT-22590445, KAKENHI-PROJECT-22689017, KAKENHI-PROJECT-23390121, KAKENHI-PLANNED-20113003, KAKENHI-PUBLICLY-24117723
[Journal Article] A novel mechanism for the autonomous termination of pre-B cell receptor expression via induction of lysosomal-associated protein transmembrane 5.2012
- Author(s)
  Yohei Kawano
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 32 Issue: 21 Pages: 4462-4471
- DOI
  10.1128/mcb.00531-12
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390097, KAKENHI-PROJECT-22590445, KAKENHI-PROJECT-23790530, KAKENHI-PROJECT-24659225
[Journal Article] LAPTM5 is a positive regulator of pro-inflammatory signaling pathways in macrophages2012
- Author(s)
  Glowacka, W.K., Alberts, P., Ouchida, R., Wang, J.-Y. and Rotin, D.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 287 Issue: 33 Pages: 27691-27702
- DOI
  10.1074/jbc.m112.355917
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590445
[Journal Article] Rapid cell division contributes to efficient induction of A/T mutations during Ig gene hypermutation2011
- Author(s)
  Kano C, Ouchida R, Kokubo T, Wang J-Y
- Journal Title
  
  Mol.Immunol.
  
  Volume: 48(15-16) Pages: 1993-1999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790482
[Journal Article] Rapid cell division contributes to efficient induction of A/T mutations during Ig gene hypermutation2011
- Author(s)
  Kano C, Ouchida R, Kokubo T, Wane JY
- Journal Title
  
  Molecular Immunology
  
  Volume: 48(15-16) Issue: 15-16 Pages: 1993-1999
- DOI
  10.1016/j.molimm.2011.06.218
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-22113517, KAKENHI-PROJECT-22590445, KAKENHI-PROJECT-23370077
[Journal Article] Rapid cell division contributes to efficient induction of A/T mutations during Ig gene hypermutation2011
- Author(s)
  狩野智恵、大内田理佳、古久保哲朗、王継揚
- Journal Title
  
  Molecular Immunology
  
  Volume: 48巻 Pages: 1993-1999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790482
[Journal Article] A role for lysosomal-associated protein transmembrane 5 in the negative regulation of surface BCR levels and B cell activation2010
- Author(s)
  Ouchida, R., Kurosaki, T. and Wang, J.-Y.
- Journal Title
  
  J. Immunol.
  
  Volume: 185 Issue: 1 Pages: 294-301
- DOI
  10.4049/jimmunol.1000371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590445
[Journal Article] A role for lysosomal-associated protein transmembrane 5 in the negative regulation of surface B cell receptor levels and B cell activation2010
- Author(s)
  大内田理佳、黒崎知博、王継揚
- Journal Title
  
  The Journalof Immunology
  
  Volume: 185巻 Pages: 294-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790482
[Journal Article] A role for lysosomal-associated protein transmembrane 5 in the negative regulation of surface BCR levels and B cell activation.2010
- Author(s)
  Ouchida, R., Kurosaki, T., Wang, J.-Y.
- Journal Title
  
  J.Immunol.
  
  Volume: 185 Pages: 294-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590445
[Journal Article] A role for lysosomal-associated protein transmembrane 5 in the negative regulation of surface B cell receptor levels and B cell activation.2010
- Author(s)
  Rika Ouchida
- Journal Title
  
  The Journal of Immunology
  
  Volume: 185 Pages: 294-301
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790482
[Journal Article] TCRのリソソームでの分解とLAPTM52009
- Author(s)
  大内田理佳、王継揚
- Journal Title
  
  感染・炎症・免疫 39巻-1
  
  Pages: 41-43
- Data Source
  KAKENHI-PROJECT-20790382
[Journal Article] A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3 zeta-chain degradation2008
- Author(s)
  大内田理佳
- Journal Title
  
  Immunity 29
  
  Pages: 33-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790382
[Journal Article] A lysosomal protein negatively regulates surface T cell antigen receptor expression by promoting CD3zeta-chain degradation.2008
- Author(s)
  大内田理佳(15名中1番目)
- Journal Title
  
  Immunity 29
  
  Pages: 33-43
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790382
[Patent] 肺炎球菌表層タンパク質2020
- Inventor(s)
  幸義和・中橋理佳・清野宏
- Industrial Property Rights Holder
  幸義和・中橋理佳・清野宏
- Industrial Property Rights Type
  特許
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-17K08821
[Patent] 細胞性免疫を誘導する経鼻ワクチン2019
- Inventor(s)
  幸義和・中橋理佳・清野宏
- Industrial Property Rights Holder
  幸義和・中橋理佳・清野宏
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-17K08821
[Patent] 細胞性免疫を誘導する経鼻ワクチン2018
- Inventor(s)
  清野宏、中橋理佳、幸義和
- Industrial Property Rights Holder
  清野宏、中橋理佳、幸義和
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2018-014651
- Filing Date
  2018
- Data Source
  KAKENHI-PROJECT-17K08821
[Presentation] The role of maternal IgG antibody during brain development2016
- Author(s)
  大内田　理佳
- Organizer
  日本免疫学会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-26430081
[Presentation] The Fc receptor for IgM (FcμR) positively regulates primary and memory B cell responses2012
- Author(s)
  Ouchida R, Mori H, Hase K, Kurosaki T, Ohno H, Wang J-Y
- Organizer
  Keystone Symposium on Regulation of Lymphocyte Signaling
- Place of Presentation
  Keystone, USA
- Year and Date
  2012-03-13
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] The lysosomal protein LAPTM5 negatively regulates B cell activation and antibody production by downmodulating cell surface BCR expression2010
- Author(s)
  Ouchida, R., Wang, J.-Y.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] A transcription factor regulates apoptosis of germinal center B cells and the production of high-affinity antibodies2010
- Author(s)
  Li Y., Ouchida, R., Wang, J.-Y.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] The lysosomal protein LAPTM5 negatively regulates B cell activation and antibody production by downmodulating cell surface BCR expression2010
- Author(s)
  Ouchida R, Mori H, Wang J-Y
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] Induction of A:T mutations is dependent on cellular environment but independent of mutation frequency and target gene location2010
- Author(s)
  Kano C, Ouchida R, Moritan T, Wang J-Y
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] The lysosomal protein LAPTM5 negatively regulates B cell activation and antibody production by downmodulating cell surface BCR expression2010
- Author(s)
  大内田理佳
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22790482
[Presentation] A transcription factor regulates apoptosis of germinal center B cells and the production of high-affinity antibodies2010
- Author(s)
  Li Y, Ouchida R, Wang J-Y
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] LAPTM5 controls B cell antigen receptor levels and negatively regulates B cell activation2010
- Author(s)
  Ouchida R, Wang J-Y
- Organizer
  Keystone Symposium on Lymphocyte Activation and Gene Expression
- Place of Presentation
  Breckenridge, USA
- Year and Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] A critical role for REV1 in induction of C : G transitions and A : T mutations during immunoglobulin gene hypermutation2010
- Author(s)
  Masuda K., Li Y., Ouchida, R.Mori H., Wang, J.-Y.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] The autonomous termination of pre-BCR expression through BLNK-mediated induction of LAPTM52010
- Author(s)
  Kawano Y, Ouchida R, Wang J, Yoshikawa S, Yamamoto M, Kitamura D, Karasuyama H
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-24
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] The lysosomal protein LAPTM5 negatively regulates B cell activation and antibody production by downmodulating cell surface BCR expression2010
- Author(s)
  Rika Ouchida
- Organizer
  第14回国際免疫学会
- Place of Presentation
  神戸
- Year and Date
  2010-08-23
- Data Source
  KAKENHI-PROJECT-22790482
[Presentation] Induction of A : T mutations is dependent on cellular environment but independent of mutation frequency and target gene location2010
- Author(s)
  Kano C., Ouchida, R., Moritan T., Wang, J.-Y.
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-22590445
[Presentation] A critical role for REV1 in induction of C:G transitions and A:T mutations during immunoglobulin gene hypermutation2010
- Author(s)
  Masuda K, Li Y, Ouchida R, Mori H, Wang J-Y
- Organizer
  14^<th> International Congress of Immunology
- Place of Presentation
  Kobe, Japan
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-22590445

1. WANG Jiyang (80231041)

# of Collaborated Projects: 3 results

# of Collaborated Products: 16 results
2. Fujihashi Kohtaro (50820354)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. 増田啓次 (60392122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 幸義和 (60345030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 片岡宏介 (50283792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 落合智子 (20130594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 古久保哲朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 鍔田武志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 川口寧

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAHASHI RIKA 中橋 理佳

Nakahashi Rika 中橋 理佳

Ouchida Rika 大内田 理佳

OUCHIDA Rika 大内田 理佳

大内田 理佳 オオウチダ リカ

Research Projects

Research Products

Co-Researchers

Development of an intranasal vaccine to prevent respiratory infections that cause exacerbations of chronic obstructive pulmonary disease.Principal Investigator

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抗原非依存型ダブルシグナルシステムによる老化粘膜免疫の再生

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Rejuvenation of mucosal immunosenescence by the sublingual vaccine: The prevention and treatment for periodontal disease and arteriosclerosis

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Basic research for the TB vaccine development based on the novel drug delivery system.Principal Investigator

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Role of microglia on brain development through maternal IgG-Fcgamma receptor pathway.Principal Investigator

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Role of IgM Fc receptor in enhancing humoral immune responses and preventing autoimmunity

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Mechanisms of the induction of A:T mutations in the germinal center B cells

Principal Investigator

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Analysis of BCR degradation by a lysosomal protein LAPTM5Principal Investigator

Principal Investigator

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Research Institution

Analysis of TCR regulation by a lysosomal protein LAPTM5Principal Investigator

Principal Investigator

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Bリンパ球の生存、増殖及びゲノム変異に果すDNAポリメラーゼシータの役割の解明

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] MucoRice-CTB line 19A, a new marker-free transgenic rice-based cholera vaccine produced in an LED-based hydroponic system2024

Author(s)

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DOI

Data Source

[Journal Article] Glycoprotein 2 as a gut gate keeper for mucosal equilibrium between inflammation and immunity.2023

Author(s)

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[Journal Article] Cationic-nanogel nasal vaccine containing the ectodomain of RSV-small hydrophobic protein induces protective immunity in rodents2023

Author(s)

NAKAHASHI RIKA 中橋理佳

Nakahashi Rika 中橋理佳

Ouchida Rika 大内田理佳

OUCHIDA Rika 大内田理佳

大内田理佳オオウチダリカ