YOKOO Tomotaka 横尾友隆

… Alternative Names

横尾友隆ヨコオトモタカ

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Researcher Number	80400688
Other IDs
Affiliation (Current)	2025: 埼玉医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 埼玉医科大学, 医学部, 准教授 2019 – 2020: 埼玉医科大学, 医学部, 准教授 2018: 埼玉医科大学, 医学部, 講師 2012 – 2015: 埼玉医科大学, 医学部, 助教 2010: Saitama Medical University, 医学部, 助教 2009: Jichi Medical University, 医学部, ポストドクター 2007 – 2008: 自治医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Endocrinology / Basic Section 59040:Nutrition science and health science-related / Metabolomics Except Principal Investigator Basic Section 54040:Metabolism and endocrinology-related / Metabolomics / Basic Section 46020:Anatomy and histopathology of nervous system-related / Endocrinology
Keywords	Principal Investigator 糖尿病 / 膵β細胞 / 遺伝子発現 / 生活習慣病 Except Principal Investigator 糖尿病 / 消化管ホルモン / 遺伝子改変マウス / ペプチド / アミロイドβ蛋白 / アミロイド前駆体蛋白 … More / アポリポプロテインE / アルツハイマー病 / 新規分泌タンパク / ピオグリタゾン / インスリン抵抗性 / mitoNEET / 骨格筋 / PPARδ Less

消化管ペプチドBetageninを標的とした膵島移植による糖尿病治療へ向けた検討
- Principal Investigator
  
  豊島秀男
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Saitama Medical University
消化管由来ペプチドBetageninのシグナル伝達の解明と糖尿病治療への応用Principal Investigator
- Principal Investigator
  
  横尾友隆
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Saitama Medical University
Targeting apolipoprotein E for Alzheimer's disease therapy.
- Principal Investigator
  
  森隆
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46020:Anatomy and histopathology of nervous system-related
- Research Institution
  Saitama Medical University
Identification of receptor for novel intestinal secretory protein, Betagenin, and application to diabetes treatment.
- Principal Investigator
  
  Toyoshima Hideo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Saitama Medical University
Elucidation of pancreatic beta-cell proliferation and differentiation mechanism by novel intestinal secretory protein IBCAP (betagenin).Principal Investigator
- Principal Investigator
  
  Yokoo Tomotaka
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  Saitama Medical University
The analysis of the novel intestinal hormone, IBCAP (Betagenin) in the pancreatic beta-cells functions.
- Principal Investigator
  
  Toyoshima Hideo
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Endocrinology
- Research Institution
  Saitama Medical University
Application of the novel intestinal hormone, IBCAP targeted pancreas beta-cell regeneration therapy.Principal Investigator
- Principal Investigator
  
  YOKOO TOMOTAKA
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Endocrinology
- Research Institution
  Saitama Medical University
Functional analysis of the novel intestinal hormone, IBCAP withincretin-like activity
- Principal Investigator
  
  TOYOSHIMA Hideo
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  Saitama Medical University
Identification and characterization of the new therapy target for metabolic syndromePrincipal Investigator
- Principal Investigator
  
  YOKOO Tomotaka
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Metabolomics
- Research Institution
  Saitama Medical University
  Jichi Medical University
Research on the effects of skeletal muscle specific expression of PPARδ on insulin resistance
- Principal Investigator
  
  SUZUKI Hiroaki
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Metabolomics
- Research Institution
  University of Tsukuba

All 2019 2018 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation Patent

[Journal Article] Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment2019
- Author(s)
  Ochiai Nagahiro、Nakachi Yutaka、Yokoo Tomotaka、Ichihara Takahiro、Eriksson Tore、Yonemoto Yuki、Kato Takehiko、Ogata Hitoshi、Fujimoto Natsuko、Kobayashi Yasuhiro、Udagawa Nobuyuki、Kaku Shinsuke、Ueki Tomokazu、Okazaki Yasushi、Takahashi Naoyuki、Suda Tatsuo
- Journal Title
  
  Communications Biology
  
  Volume: 2 Issue: 1 Pages: 1-13
- DOI
  10.1038/s42003-019-0334-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08487, KAKENHI-PROJECT-16H05144, KAKENHI-PROJECT-19K10395, KAKENHI-PROJECT-16H02691, KAKENHI-PROJECT-20K20394, KAKENHI-PROJECT-17K19776
[Journal Article] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012
- Author(s)
  Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Masanobu KAWAKAMI, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
- Journal Title
  
  Diabetologia
  
  Volume: 55 Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659453
[Journal Article] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012
- Author(s)
  Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Masanobu KAWAKAMI, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
- Journal Title
  
  Diabetologia
  
  Volume: 55 Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590992
[Journal Article] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver2012
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
- Journal Title
  
  Diabetologia
  
  Volume: 55(Suppl1) Issue: S1 Pages: 1-538
- DOI
  10.1007/s00125-012-2688-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590992, KAKENHI-PROJECT-24659453
[Journal Article] IBCAP, Intestine-specific Secretory Protein with Incretin-like Activity2011
- Author(s)
  Yokoo T, Suzuki H, Shimano H, Watanabe K, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
- Journal Title
  
  Diabetes
  
  Volume: 60 Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590992
[Journal Article] IBCAP, Intestine- specific Secretory Protein with Incretin-like Activity2011
- Author(s)
  Yokoo T, Suzuki H, Shimano H, Watanabe K, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
- Journal Title
  
  Diabetes
  
  Volume: 60(Suppl1) Issue: Supplement_1 Pages: A521-A548
- DOI
  10.2337/db11-1929-2041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590992
[Journal Article] Transgenic mice expressing an intestine-specific secretory protein, IBCAP, demonstrates pancreatic beta cell augmenting activity2010
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa SE, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
- Journal Title
  
  Diabetologia
  
  Volume: 53(Suppl1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590992
[Journal Article] Transgenic mice expressing an intestine-specific secretory protein, IBCAP, demonstrates pancreatic beta cell augmenting activity2010
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa S-E, Kawakami M, Okazaki Y, Yamada N, Toyoshima H
- Journal Title
  
  Diabetologia 53(Suppl1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790879
[Journal Article] Transgenic mice expressing an intestine-specific secretory protein, IBCAP, demonstrates pancreatic beta cell augmenting activity2010
- Author(s)
  Tomotaka YOKOO
- Journal Title
  
  Diabetologia
  
  Volume: 53(Suppl1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790879
[Journal Article] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic ss-Cell Augmenting Activity.2010
- Author(s)
  Tomotaka YOKOO
- Journal Title
  
  Endocrine Reviews
  
  Volume: 31(3)Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590992
[Journal Article] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic ss-Cell Augmenting Activity.2010
- Author(s)
  Tomotaka YOKOO
- Journal Title
  
  Endocrine Reviews
  
  Volume: 31(3) Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790879
[Journal Article] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic β-Cell Augmenting Activity2010
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa SE, Kawakami M, Yamada N, Toyoshima H
- Journal Title
  
  Endocrine Reviews
  
  Volume: 31(3) Suppl 1
- URL
  http://www.endojournals.org/site/abstracts/P1-1_to_P1-729.pdf
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590992
[Journal Article] Transgenic mice expressing an intestine-specific secretory protein, IBCAP, demonstrates pancreatic beta cell augmenting activity2010
- Author(s)
  Tomotaka YOKOO
- Journal Title
  
  Diabetologia
  
  Volume: 53(Suppl1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590992
[Journal Article] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic β-Cell Augmenting Activity.2010
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa S-E, Kawakami M, Yamada N, Toyoshima H
- Journal Title
  
  Endocrine Reviews 31(3) Suppl 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790879
[Journal Article] SPARC is a major secretory gene expressed and involved in the development of proliferative diabetic retinopathy.2009
- Author(s)
  Watanabe K, Okamoto F, Yokoo T, Iida KT, Suzuki H, Ishikawa S, Kawakami M, Shimano H, Oshika T, Yamada N, Toyoshima H.
- Journal Title
  
  J Atheroscler Thromb. 16(2)
  
  Pages: 69-76
- NAID
  10025764920
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790879
[Journal Article] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IMCAP (Formerly CF266), Demonstrates Pancreatic β-Cell Augmenting Activity.2009
- Author(s)
  Yokoo T, Watanabe K, Tada-Iida K, Suzuki H, Shimano H, Ishikawa S-E, Kawakami M, Yamada N, Toyoshima H
- Journal Title
  
  Diabetes 58,Suppl(1)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790879
[Patent] 膵臓ホルモン産生細胞の生産方法及び膵臓ホルモン産生細胞、並びに分化誘導促進剤2013
- Inventor(s)
  豊島秀男、岡崎康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  埼玉医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-05-24
- Overseas
- Data Source
  KAKENHI-PROJECT-24659453
[Patent] 新規ペプチド及びその用途2013
- Inventor(s)
  豊島秀男、岡﨑康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  学校法人　埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-109801
- Filing Date
  2013
- Data Source
  KAKENHI-PROJECT-25461395
[Patent] 膵臓内分泌細胞の生産方法2013
- Inventor(s)
  豊島秀男、岡崎康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  埼玉医科大学
- Filing Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-22590992
[Patent] 新規ペプチド及びその用途2013
- Inventor(s)
  豊島秀男、岡崎康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-109801
- Filing Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-24659453
[Patent] 膵臓ホルモン産生細胞の生産方法及び膵臓ホルモン産生細胞、並びに分化誘導促進剤2013
- Inventor(s)
  豊島秀男、岡﨑康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  学校法人　埼玉医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013
- Overseas
- Data Source
  KAKENHI-PROJECT-25461395
[Patent] 膵臓ホルモン産生細胞の生産方法及び膵臓ホルモン産生細胞、並びに分化誘導促進剤2013
- Inventor(s)
  豊島秀男、岡﨑康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  学校法人　埼玉医科大学
- Industrial Property Rights Type
  特許
- Filing Date
  2013-05-24
- Overseas
- Data Source
  KAKENHI-PROJECT-24659453
[Patent] 新規ペプチド及びその用途2013
- Inventor(s)
  豊島秀男、岡﨑康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  学校法人　埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2013-109801
- Filing Date
  2013-05-24
- Data Source
  KAKENHI-PROJECT-24659453
[Patent] 膵臓内分泌細胞の生産方法2012
- Inventor(s)
  豊島秀男、岡﨑康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-120281
- Filing Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-24659453
[Patent] 膵臓内分泌細胞の生産方法2012
- Inventor(s)
  豊島秀男、岡﨑康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-120281
- Filing Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-22590992
[Patent] 膵臓内分泌細胞の生産方法2012
- Inventor(s)
  豊島秀男、岡崎康司、横尾友隆、菅原泉
- Industrial Property Rights Holder
  埼玉医科大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2012-120281
- Filing Date
  2012-05-25
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] 消化管由来分泌タンパクBetageninによる糖尿病治療効果の解析2019
- Author(s)
  横尾友隆、島野仁、岡崎康司、豊島秀男
- Organizer
  第17回RCGMフロンティアシンポジウム
- Data Source
  KAKENHI-PROJECT-18K08487
[Presentation] 消化管ペプチドBetageninはヒト膵島のアポトーシスを抑制し,増殖とインスリン分泌を促進する2018
- Author(s)
  横尾友隆、島野仁、岡崎康司、豊島秀男
- Organizer
  第61回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K08487
[Presentation] 消化管ペプチドBetageninはヒトβ細胞のアポトーシスを抑制し、増殖とインスリン分泌を促進する2018
- Author(s)
  豊島秀男、横尾友隆、島野仁、岡崎康司
- Organizer
  第91回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K08487
[Presentation] 新規消化管ホルモン Betagenin は膵β細胞の増殖を刺激し糖尿病を改善する2015
- Author(s)
  横尾友隆、渡邉和寿、飯田薫子、鈴木浩明、高島成二、島野仁、山田信博、岡崎康司、豊島秀男
- Organizer
  第13回 RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉医科大学創立30週年記念講堂（埼玉県日高市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-26670462
[Presentation] Betagenin, a novel intestinal hormone, increases β-cell and alleviates diabetes.2015
- Author(s)
  Hideo Toyoshima, Tomotaka Yokoo
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関市民会館（山口県下関市）
- Year and Date
  2015-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-25461395
[Presentation] 新規消化管ホルモン Betagenin は膵β細胞の増殖を刺激し糖尿病を改善する2015
- Author(s)
  横尾友隆、渡邉和寿、飯田薫子、鈴木浩明、高島成二、島野仁、山田信博、岡崎康司、豊島秀男
- Organizer
  第13回 RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉医科大学創立30週年記念講堂（埼玉県日高市）
- Year and Date
  2015-10-31
- Data Source
  KAKENHI-PROJECT-25461395
[Presentation] Betagenin, a novel intestinal hormone, increases β-cell and alleviates diabetes.2015
- Author(s)
  Hideo Toyoshima, Tomotaka Yokoo
- Organizer
  第58回日本糖尿病学会年次学術集会
- Place of Presentation
  下関市民会館（山口県下関市）
- Year and Date
  2015-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-26670462
[Presentation] iPS細胞を用いた、新規消化管ホルモンIBCAPが膵β細胞分化に与える影響の検討2014
- Author(s)
  菅原泉、横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、山田信博、岡﨑康司、豊島秀男
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-25461395
[Presentation] iPS細胞を用いた、新規消化管ホルモンIBCAPが膵β細胞分化に与える影響の検討2014
- Author(s)
  菅原泉、横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、山田信博、岡﨑康司、豊島秀男
- Organizer
  第57回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場（大阪府大阪市）
- Year and Date
  2014-05-22
- Data Source
  KAKENHI-PROJECT-26670462
[Presentation] 消化管ホルモンIBCAPによる膵β細胞分化増殖に与える影響2013
- Author(s)
  豊島秀男、横尾友隆、鈴木浩明、石川三衛、川上正舒、島野仁、山田信博、岡崎康司
- Organizer
  第86回日本内分泌学会学術集会
- Place of Presentation
  宮城県仙台市
- Year and Date
  2013-04-25
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] 膵β細胞分化における消化管ホルモンIBCAPの役割2013
- Author(s)
  横尾友隆、菅原泉、渡邊和寿、鈴木浩明、島野仁、山田信博、岡崎康司、豊島秀男
- Organizer
  第11回RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉県日高市
- Year and Date
  2013-11-23
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] 新規消化管ホルモンIBCAPによる膵β細胞分化・増殖作用の解析2013
- Author(s)
  横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博、岡崎康司、豊島秀男
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  熊本県熊本市
- Year and Date
  2013-05-16
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver2012
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Kawakami M, Yamada N, Okazaki Y, Toyoshima H.
- Organizer
  48th EASD Annual Meeting
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-10-02
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012
- Author(s)
  Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Masanobu KAWAKAMI, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
- Organizer
  第48回欧州糖尿病学会議 (EASD)
- Place of Presentation
  Messe Berlin（ドイツ、ベルリン）
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] Effect of IBCAP, a Novel Intestine-specific Secretory Protein, on Pancreatic β-cell Differentiation.2012
- Author(s)
  Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
- Organizer
  第10回 RCGMフロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学（埼玉県日高市）
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] Effect of IBCAP, a Novel Intestine-specific Secretory Protein, on Pancreaticβ-cell Differentiation2012
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Yamada N, Okazaki Y, Toyoshima H.
- Organizer
  第10回RCGMフロンティア国際シンポジウム
- Place of Presentation
  埼玉県日高市
- Year and Date
  2012-11-03
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver2012
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
- Organizer
  48th EASD Annual Meeting
- Place of Presentation
  Berlin, Germany
- Year and Date
  2012-10-02
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] Effect of IBCAP, a Novel Intestine-specific Secretory Protein, on Pancreatic β-cell Differentiation.2012
- Author(s)
  Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
- Organizer
  第10回 RCGMフロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学（埼玉県日高市）
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012
- Author(s)
  Tomotaka YOKOO, Kazuhisa WATANABE, Kaoruko Tada IIDA, Hiroaki SUZUKI, Hitoshi SHIMANO, Masanobu KAWAKAMI, Nobuhiro YAMADA, Yasushi OKAZAKI, Hideo TOYOSHIMA
- Organizer
  第48回欧州糖尿病学会議 (EASD)
- Place of Presentation
  Messe Berlin（ドイツ、ベルリン）
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] 新規消化管ホルモン因子IBCAPによる膵β細胞増加作用の解析2011
- Author(s)
  横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博、岡崎康司、豊島秀男
- Organizer
  第26回日本糖尿病合併症学会
- Place of Presentation
  さいたま市
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] 膵 β 細胞増加作用を持つ新規消化管特異的分泌タンパクIBCAPの機能解析2011
- Author(s)
  横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博、岡崎康司、豊島秀男
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] 膵β細胞増加作用を持つ新規消化管特異的分泌タンパクIBCAPの機能解析2011
- Author(s)
  横尾友隆
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  北海道札幌市
- Year and Date
  2011-05-19
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] 新規消化管特異的分泌因子IBCAPの機能解析および糖尿病治療への可能性2011
- Author(s)
  豊島秀男 [招待演者]、横尾友隆、鈴木浩明、石川三衛、川上正舒、島野仁、山田信博、岡崎康司
- Organizer
  第84回日本内分泌学会学術総会
- Place of Presentation
  神戸市
- Year and Date
  2011-04-22
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] Demonstration of IBCAP as a Novel Intestine- specific Secretory Protein with Incretin-like Activity2011
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
- Organizer
  第34回日本分子生物学学会年会
- Place of Presentation
  横浜市
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] 新規消化管ホルモン因子IBCAPによる膵β細胞増加作用の解析2011
- Author(s)
  横尾友隆
- Organizer
  第26回日本糖尿病合併症学会
- Place of Presentation
  埼玉県さいたま市
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] IBCAP, Intestine-specific Secretory Protein with Incretin-like Activity2011
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa SE, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
- Organizer
  The 71st Scientific Sessions of America Diabetes Association
- Place of Presentation
  San Diego, USA
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] 膵β細胞増加促進作用を持つ新規消化管ホルモンIBCAPの解析2011
- Author(s)
  横尾友隆
- Organizer
  第9回RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉県日高市
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] Demonstration of IBCAP as a Novel Inte stine-specific Secretory Protein with Incretin-like Activity2011
- Author(s)
  Tomotaka Yokoo
- Organizer
  第34回日本分子生物学学会年会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2011-12-14
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] IBCAP, Intestine-specific Secretory Protein with Incretin-like Activity2011
- Author(s)
  Tomotaka Yokoo
- Organizer
  The 71^<st> Scientific Sessions of America Diabetes Association
- Place of Presentation
  San Diego (USA)
- Year and Date
  2011-06-27
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic β-Cell Augmenting Activity.2010
- Author(s)
  Tomotaka Yokoo, Kazuhisa Watanabe, Kaoruko Tada Iida, Hiroaki Suzuki, Hitoshi Shimano, San-e Ishikawa, Masanobu Kawakami, Nobuhiro Yamada, Hideo Toyoshima.
- Organizer
  ENDO 2010: The 92nd Annual Meeting & Expo
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic β-Cell Augmenting Activity2010
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa SE, Kawakami M, Yamada N, Toyoshima H
- Organizer
  ENDO 2010: The 92nd Annual Meeting & Expo
- Place of Presentation
  San Diego, USA
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] インスリン分泌刺激作用を持つ新規消化管特異的分泌タンパクIBCAPの機能解析2010
- Author(s)
  横尾友隆
- Organizer
  第8回 RCGMフロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学(埼玉県日高市)
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] Transgenic mice expressing an intestine-specific secretory protein, IBCAP demonstrates pancreatic beta cell augmenting activity.2010
- Author(s)
  Tomotaka YOKOO
- Organizer
  第46回欧州糖尿病学会議(EASD)
- Place of Presentation
  STOCKHOLMSMASSAN(ストックホルム)(Sweden)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic ss-Cell Augmenting Activity.2010
- Author(s)
  Tomotaka YOKOO
- Organizer
  第92回米国内分泌学会年次集会(ENDO 2010)
- Place of Presentation
  San Diego Convention Center(サンディエゴ),(USA)
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] Transgenic mice expressing an intestine-specific secretory protein, IBCAP, demonstrates pancreatic beta cell augmenting activity.2010
- Author(s)
  Tomotaka YOKOO
- Organizer
  第46回欧州糖尿病学会議(EASD)
- Place of Presentation
  STOCKHOLMSMASSAN(ストックホルム)
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] インスリン分泌刺激作用を持つ新規消化管特異的分泌タンパクIBCAPの機能解析2010
- Author(s)
  横尾友隆
- Organizer
  第8回 RCGMフロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学(埼玉県日高市)
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] Transgenic mice expressing an intestine-specific secretory protein, IBCAP, demonstrates pancreatic beta cell augmenting activity2010
- Author(s)
  Yokoo T, Watanabe K, Iida KT, Suzuki H, Shimano H, Ishikawa SE, Kawakami M, Yamada N, Okazaki Y, Toyoshima H
- Organizer
  46th EASD Annual Meeting
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic ss-Cell Augmenting Activity.2010
- Author(s)
  Tomotaka YOKOO
- Organizer
  第92回米国内分泌学会年次集会(ENDO 2010)
- Place of Presentation
  San Diego Convention Center(サンディエゴ)
- Year and Date
  2010-06-19
- Data Source
  KAKENHI-PROJECT-22590992
[Presentation] Transgenic mice expressing an intestine-specific secretory protein, IBCAP, demonstrates pancreatic beta cell augmenting activity.2010
- Author(s)
  Tomotaka Yokoo, Kazuhisa Watanabe, Kaoruko Tada Iida, Hiroaki Suzuki, Hitoshi Shimano, San-e Ishikawa, Masanobu Kawakami, Nobuhiro Yamada, Yasushi Okazaki, Hideo Toyoshima.
- Organizer
  46th EASD Annual Meeting
- Place of Presentation
  Stockholm, Sweden
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic β-Cell Augmenting Activity.2009
- Author(s)
  Tomotaka Yokoo, Kazuhisa Watanabe, Kaoruko Tada Iida, Hiroaki Suzuki, Hitoshi Shimano, San-e Ishikawa, Masanobu Kawakami, Nobuhiro Yamada, Hideo Toyoshima.
- Organizer
  The 69th Scientific Sessions of America Diabetes Association
- Place of Presentation
  New Orleans
- Year and Date
  2009-06-08
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] Transgenic Mice Expressing an Intestine-Specific Secretory Protein, IBCAP (Formerly CF266), Demonstrates Pancreatic β-Cell Augmenting Activity.2009
- Author(s)
  Tomotaka YOKOO
- Organizer
  第69回アメリカ糖尿病学会学術大会
- Place of Presentation
  Morial Convention Center(ニューオリンズ)
- Year and Date
  2009-06-08
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] 膵β細胞増加作用を持つ新規消化管特異的分泌タンパクIBCAPの解析2009
- Author(s)
  横尾友隆
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪国際会議場(大阪)
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] 膵β細胞増加作用を持つ新規消化管特異的分泌タンパクIBCAPの解析2009
- Author(s)
  横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博、豊島秀男
- Organizer
  第52回日本糖尿病学会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2009-05-23
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] Identification and Characterization of IBCAP, a Novel Intestine-specific Secretory Protein with Pancreatic Beta-cell Augmenting Activity.2009
- Author(s)
  横尾友隆
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(横浜)
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] Identification and Characterization of IBCAP, a Novel Intestine-specific Secretory Protein with Pancreatic Beta-cell Augmenting Activity.2009
- Author(s)
  横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博、豊島秀男
- Organizer
  第32回日本分子生物学学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] 新規消化管特異的分泌タンパクIBCAPの機能解析2009
- Author(s)
  横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博、豊島秀男
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] 膵β細胞増加作用を持つ新規消化管特異的分泌タンパクIBCAPの解析2009
- Author(s)
  豊島秀男、横尾友隆、渡邊和寿、飯田薫子、鈴木浩明、島野仁、石川三衛、川上正舒、山田信博
- Organizer
  第82回日本内分泌学会学術集会
- Place of Presentation
  前橋
- Year and Date
  2009-04-23
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] 新規消化管特異的分泌タンパクIBCAPの機能解析2009
- Author(s)
  横尾友隆
- Organizer
  第82回日本生化学会大会
- Place of Presentation
  神戸国際会議場(神戸)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21790879
[Presentation] ピオグリタゾン結合タンパクmitoNEETの機能解析2008
- Author(s)
  渡邉和寿, 大木真也, 横尾友隆, 鈴木浩明, 島野仁, 石川三衛, 川上正舒, 山田信博, 豊島秀男
- Organizer
  第40回日本動脈硬化学会総会・学術集会
- Place of Presentation
  つくば
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19591033
[Presentation] ピオグリタゾン結合タンパクmitoNEETの機能解析2008
- Author(s)
  大木真也, 渡邉和寿, 横尾友隆, 鈴木浩明, 高橋昭光, 矢藤繁, 小林和人, 島野仁, 石川三衛, 山田信博, 豊島秀男
- Organizer
  第51回日本糖尿病学会年次学術集会
- Place of Presentation
  東京
- Year and Date
  2008-05-22
- Data Source
  KAKENHI-PROJECT-19591033
[Presentation] ピオグリタゾン結合蛋白mitoNEETの機能解析2008
- Author(s)
  渡邉和寿, 大木真也, 横尾友隆, 鈴木浩明, 高橋昭光, 矢藤繁, 小林和人, 島野仁, 石川三衛, 川上正舒, 山田信博, 豊島秀男
- Organizer
  第45回日本臨床分子医学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2008-07-24
- Data Source
  KAKENHI-PROJECT-19591033
[Presentation] 消化管ホルモンIBCAPによる膵β細胞分化増殖に与える影響
- Author(s)
  豊島　秀男、横尾　友隆、鈴木　浩明、石川　三衛、川上　正舒、島野　仁、山田　信博、岡崎　康司
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-25461395
[Presentation] Effect of Betagenin on Pancreatic beta-cell Proliferation and Differentiation
- Author(s)
  Tomotaka Yokoo, Yizumi Yamashita Sugawara, Kazuhisa Watanabe, Kaoruko Tada Iida, Hiroaki Suzuki, Hitoshi Shimano, Nobuhiro Yamada, Yasushi Okazaki, Hideo Toyoshima
- Organizer
  第12回 RCGMフロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学30周年記念講堂（埼玉県日高市）
- Year and Date
  2014-10-31 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-25461395
[Presentation] Effect of Betagenin on Pancreatic beta-cell Proliferation and Differentiation
- Author(s)
  Tomotaka Yokoo, Yizumi Yamashita Sugawara, Kazuhisa Watanabe, Kaoruko Tada Iida, Hiroaki Suzuki, Hitoshi Shimano, Nobuhiro Yamada, Yasushi Okazaki, Hideo Toyoshima
- Organizer
  第12回 RCGMフロンティア国際シンポジウム
- Place of Presentation
  埼玉医科大学30周年記念講堂（埼玉県日高市）
- Year and Date
  2014-10-31 – 2014-11-01
- Data Source
  KAKENHI-PROJECT-26670462
[Presentation] 消化管ホルモンIBCAPによる膵β細胞分化増殖に与える影響
- Author(s)
  豊島　秀男、横尾　友隆、鈴木　浩明、石川　三衛、川上　正舒、島野　仁、山田　信博、岡崎　康司
- Organizer
  第86回日本内分泌学会学術総会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] 膵β細胞分化における消化管ホルモンIBCAPの役割
- Author(s)
  横尾　友隆、菅原　泉、渡邉　和寿、鈴木　浩明、島野　仁、山田　信博、岡崎　康司、豊島　秀男
- Organizer
  第11回 RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉医科大学30周年記念講堂（埼玉県日高市）
- Data Source
  KAKENHI-PROJECT-24659453
[Presentation] 新規消化管ホルモンIBCAPによる膵β細胞分化・増殖作用の解析
- Author(s)
  横尾　友隆、渡邊　和寿、飯田　薫子、鈴木　浩明、島野　仁、石川　三衛、川上　正舒、山田　信博、岡崎　康司、豊島　秀男
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  テトリア熊本ビル（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-25461395
[Presentation] 膵β細胞分化における消化管ホルモンIBCAPの役割
- Author(s)
  横尾　友隆、菅原　泉、渡邉　和寿、鈴木　浩明、島野　仁、山田　信博、岡崎　康司、豊島　秀男
- Organizer
  第11回 RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉医科大学30周年記念講堂（埼玉県日高市）
- Data Source
  KAKENHI-PROJECT-25461395
[Presentation] 新規消化管ホルモンIBCAPによる膵β細胞分化・増殖作用の解析
- Author(s)
  横尾　友隆、渡邊　和寿、飯田　薫子、鈴木　浩明、島野　仁、石川　三衛、川上　正舒、山田　信博、岡崎　康司、豊島　秀男
- Organizer
  第56回日本糖尿病学会年次学術集会
- Place of Presentation
  テトリア熊本ビル（熊本県熊本市）
- Data Source
  KAKENHI-PROJECT-24659453

1. TOYOSHIMA Hideo (20197966)

# of Collaborated Projects: 8 results

# of Collaborated Products: 44 results
2. OKAZAKI Yasushi (80280733)

# of Collaborated Projects: 4 results

# of Collaborated Products: 34 results
3. SUZUKI Hiroaki (40344890)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 森隆 (60239605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 百瀬修二 (70360344)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 藤原正和 (20312069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YOKOO Tomotaka 横尾 友隆

横尾 友隆 ヨコオ トモタカ

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消化管ペプチドBetageninを標的とした膵島移植による糖尿病治療へ向けた検討

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消化管由来ペプチドBetageninのシグナル伝達の解明と糖尿病治療への応用Principal Investigator

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Targeting apolipoprotein E for Alzheimer's disease therapy.

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Identification of receptor for novel intestinal secretory protein, Betagenin, and application to diabetes treatment.

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Elucidation of pancreatic beta-cell proliferation and differentiation mechanism by novel intestinal secretory protein IBCAP (betagenin).Principal Investigator

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The analysis of the novel intestinal hormone, IBCAP (Betagenin) in the pancreatic beta-cells functions.

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Application of the novel intestinal hormone, IBCAP targeted pancreas beta-cell regeneration therapy.Principal Investigator

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Functional analysis of the novel intestinal hormone, IBCAP withincretin-like activity

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Identification and characterization of the new therapy target for metabolic syndromePrincipal Investigator

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Research on the effects of skeletal muscle specific expression of PPARδ on insulin resistance

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[Journal Article] Murine osteoclasts secrete serine protease HtrA1 capable of degrading osteoprotegerin in the bone microenvironment2019

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[Journal Article] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012

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[Journal Article] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver.2012

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[Journal Article] Expression of IBCAP (intestine-derived beta-cell augmenting promoter), an intestine specific secretory factor, induces insulin positive cells in the liver2012

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YOKOO Tomotaka 横尾友隆

横尾友隆ヨコオトモタカ

[Patent] 膵臓ホルモン産生細胞の生産方法及び膵臓ホルモン産生細胞、並びに分化誘導促進剤2013