OTSUKI Hitoshi 大槻均

… Alternative Names

Otsuki Hitoshi 大槻均

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Researcher Number	80403806
Other IDs
Affiliation (Current)	2025: 鳥取大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2015 – 2016: 鳥取大学, 医学部, 准教授 2014: 鳥取大学, 医学部, 講師 2009 – 2011: 鳥取大学, 医学部, 講師 2007 – 2009: Ehime University, Graduate School of Medicine, Department of Molecular Parasitology, Assistant Professor 2006: 愛媛大学, 大学院医学系研究科, 助手 2005: 愛媛大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Parasitology (including Sanitary zoology) / Parasitology (including sanitary zoology) Except Principal Investigator Parasitology (including Sanitary zoology)
Keywords	Principal Investigator 赤血球侵入 / マラリア原虫 / 遺伝子組換え / マラリア / 細胞内輸送 / 遺伝子導入 / 侵入 / 病原性 Except Principal Investigator 感染症 / マラリア … More / 寄生虫 / レセプター / マラリア原虫 / 原虫 / Antigenic variation / Genetic polymorphism / Parasite / Infectious Disease / 抗原変異 / 遺伝子多型 / クローニング / 遺伝子発現抑制 / プレロセルコイド / 腹腔マクロフージ / 遺伝子組み換えタンパク / RACE法 / cDNA / 遺伝子組換えタンパク質 / alternative activation / 腹腔マクロファージ / peroxiredoxin / 遺伝子発 / 旋毛虫 / マクロファージ / 免疫抑制因子 / マンソン裂頭条虫 / 侵入 / マイクロネーム / 肝細胞侵入 / 細胞侵入 / スポロゾイト / バイオテクノロジー / ゲノム / コムギ胚芽無細胞タンパク質合成系 / 赤血球接着 Less

Intracellular trafficking mechanism of erythrocyte invasion ligand molecule Plasmodium parasitesPrincipal Investigator
- Principal Investigator
  
  Otsuki Hitoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Tottori University
マラリア原虫赤血球侵入分子の細胞内輸送メカニズムの解析Principal Investigator
- Principal Investigator
  
  大槻均
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Tottori University
Identification of RBC receptors against malaria parasite molecules in the merozoite apical organelle
- Principal Investigator
  
  TSUBOI Takafumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Ehime University
Screening of sporozoite receptor molecule(s) on hepatocytes
- Principal Investigator
  
  TORII Motomi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Ehime University
A study of the effect of a recombinant immunosuppressive factor from parasites and immune-inhibitory mechanisms
- Principal Investigator
  
  FUKUMOTO Soji
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Tottori University
Identification of erythrocyte proteins interacting with RhopH complex of malaria parasites
- Principal Investigator
  
  TORII Motomi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Ehime University
Localization of erythrocyte invasion ligand defines virulence of Malaria parasitesPrincipal Investigator
- Principal Investigator
  
  OTSUKI Hitoshi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Ehime University
Association of the Plasmodium falciparuminfected erythrocyte surface molecule with ist virulence
- Principal Investigator
  
  KANEKO Osamu
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Parasitology (including Sanitary zoology)
- Research Institution
  Nagasaki University
  Ehime University

All 2017 2016 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

[Journal Article] Plasmodium vivax gametocyte protein Pvs230 is a transmission-blocking vaccine candidate2012
- Author(s)
  Tachibana M, Sato C, Otsuki H, Sattabongkot J, Kaneko O, Torii M, Tsuboi T
- Journal Title
  
  Vaccine
  
  Volume: 30 Pages: 1807-1812
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249028
[Journal Article] N-terminal pro-domain of Pfs230 synthesized using cell-free system is sufficient to induce the complement dependent malaria transmission-blocking activity2011
- Author(s)
  Tachibana M, Wu Y, Iriko H, Muratova O, Macdonald NJ, Sattabongkot J, Takeo S, Otsuki H, Torii M, Tsuboi T
- Journal Title
  
  Clin Vaccine Immunol
  
  Volume: 18 Pages: 1343-1350
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249028
[Journal Article] Plasmodial ortholog of Toxoplasma gondii rhoptry neck protein 3 is localized to the rhoptry body2011
- Author(s)
  Ito D, Han ET, Takeo S, Thongkukiatkul A, Otsuki H, Torii M, Tsuboi T
- Journal Title
  
  Parasitol Int
  
  Volume: 60 Pages: 132-138
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249028
[Journal Article] The wheat germ cell-free protein synthesis system : a key tool for novel malaria vaccine candidate discovery2010
- Author(s)
  Tsuboi T, Takeo S, Arumugam TU, Otsuki H, Torii M
- Journal Title
  
  Acta Trop
  
  Volume: 114 Pages: 171-176
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249028
[Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009
- Author(s)
  Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M.
- Journal Title
  
  Proc Natl Acad Sci (in press)(電子版)
- NAID
  120006984096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390120
[Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009
- Author(s)
  Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 106 Pages: 7167-72
- NAID
  120006984096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249028
[Journal Article] A small-scale systematic analysis of alternative splicing in Plasmodium falciparum2009
- Author(s)
  Iriko H, Jin L, Kaneko O, Takeo S, Han ET, Tachibana M, Otsuki H, Torii M, Tsuboi T
- Journal Title
  
  Parasitol Int
  
  Volume: 58 Pages: 196-9
- NAID
  10027669225
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249028
[Journal Article] Single amino acid substitution in Plasmodiun yoelii erythrocyte ligand determinesits localization and controls parasite virulence.2009
- Author(s)
  Otsuki H, Kaneko O, Thongkukiatkul. A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M
- Journal Title
  
  Rroc Natl Acad Sci USA (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390120
[Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009
- Author(s)
  大槻均、金子修、Amporn Thongkugiatkul、橘真由美、入子英幸、竹尾暁, 坪井敬文、鳥居本美
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America 電子版
  
  Pages: 1-6
- NAID
  120006984096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790308
[Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009
- Author(s)
  Otsuki H
- Journal Title
  
  Proc Natl Acad Sci USA 106
  
  Pages: 7167-7172
- NAID
  120006984096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249028
[Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009
- Author(s)
  大槻均、金子修、Amporn Thongkukiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
- Journal Title
  
  Proceedings of the National Academy of Sciences of the United States of America vol.106 no.17
  
  Pages: 7167-7172
- NAID
  120006984096
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790308
[Journal Article] Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites2009
- Author(s)
  Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Gao Q, Tsuboi T, Torii M
- Journal Title
  
  Parasitol Int
  
  Volume: 58 Pages: 29-35
- NAID
  10025329950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249028
[Presentation] マラリア原虫細胞内輸送ドメインのステージ特異性2017
- Author(s)
  大槻　均ほか
- Organizer
  第86回日本寄生虫学会大会
- Place of Presentation
  北海道大学（北海道札幌市）
- Year and Date
  2017-05-28
- Data Source
  KAKENHI-PROJECT-26460507
[Presentation] ネズミマラリア原虫赤血球侵入リガンドEBL領域4の機能解析2016
- Author(s)
  大槻均,菅井千明,入子英幸,石野智子,金子修,福本宗嗣,坪井敬文,鳥居本美
- Organizer
  第85回日本寄生虫学会大会
- Place of Presentation
  宮崎県宮崎市　宮崎市民プラザ
- Year and Date
  2016-03-19
- Data Source
  KAKENHI-PROJECT-26460507
[Presentation] 熱帯熱マラリア原虫rhoptry neck protein 3はAMA1非存在下でRON2およびRON4と複合体を形成する2011
- Author(s)
  伊藤大輔、韓銀澤、竹尾暁、Thongkukiatkul Amporn、大槻均、鳥居本美、坪井敬文
- Organizer
  第80回日本寄生虫学会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-21390124
[Presentation] 旋毛虫の新生幼虫によるマウス腹腔マクロファージのAlternative activation2011
- Author(s)
  井上菜菜瀬、福本宗嗣、大槻均、入子英幸
- Organizer
  第80回日本寄生虫学会大会
- Place of Presentation
  東京慈恵会医科大学(東京)
- Year and Date
  2011-07-18
- Data Source
  KAKENHI-PROJECT-21590464
[Presentation] 旋毛虫感染マウスにおける腹腔マクロファージのAlternative activation2010
- Author(s)
  井上菜菜瀬、入子英幸、大槻均、福本宗嗣
- Organizer
  第66回日本寄生虫学会西日本支部大会
- Place of Presentation
  岡山大学(岡山市)
- Year and Date
  2010-11-06
- Data Source
  KAKENHI-PROJECT-21590464
[Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodium yoelii 43rd Annual2009
- Author(s)
  大槻均、金子修、Amporn Thongkukiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
- Organizer
  U.S.-Japan Joint Conference on Parasitic Diseases
- Place of Presentation
  東京
- Year and Date
  2009-01-07
- Data Source
  KAKENHI-PROJECT-19790308
[Presentation] ErythrocyteBinding-Like molecule and Virulence of Plasmodium yoelii2009
- Author(s)
  大槻均、金子修、Ampom Thongku kiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
- Organizer
  43rd Annual U.S.-Japan Joint Conference on Parasitic Diseases
- Place of Presentation
  東京
- Year and Date
  2009-01-07
- Data Source
  KAKENHI-PROJECT-19790308
[Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodiun yoelii.2008
- Author(s)
  Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, TsuboiT, Torii M
- Organizer
  19th Annual Molecular Parasitology Meeting
- Place of Presentation
  Woods Hole, USA
- Data Source
  KAKENHI-PROJECT-19390120
[Presentation] A complex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plasmodium falciparum2008
- Author(s)
  Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Tsuboi T, Torii M.
- Organizer
  57^<th> ASTMH Annual Meeting, New Orleans
- Place of Presentation
  USA
- Year and Date
  2008-07-11
- Data Source
  KAKENHI-PROJECT-19390120
[Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodium yoelii Molecular Parasitology Meeting2008
- Author(s)
  大槻均、金子修、Ampom Thongku kiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
- Organizer
  Molecular Parasitology Meeting
- Place of Presentation
  米国マサチューセッチュ州ウッズホール
- Year and Date
  2008-09-21
- Data Source
  KAKENHI-PROJECT-19790308
[Presentation] A ccmplex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plasmodium falciparum.2008
- Author(s)
  曹俊, 金子修, Thongkukiatkul Amporn, 橘真由美, 大槻均, 坪井敬文, 鳥居本美
- Organizer
  第77回日本寄生虫学会大会
- Place of Presentation
  長崎市
- Data Source
  KAKENHI-PROJECT-19390120
[Presentation] A complex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plasmodium falciparuum.2008
- Author(s)
  Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Tsuboi T, Torii M
- Organizer
  57^<th> ASTMH Annual Meeting
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-19390120
[Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodium yoelii2008
- Author(s)
  大槻均、金子修、Amporn Thongkukiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
- Organizer
  Molecular Parasitology Meeting
- Place of Presentation
  米国
- Year and Date
  2008-09-21
- Data Source
  KAKENHI-PROJECT-19790308
[Presentation] ネズミマラリア原虫の赤血球結合分子EBLの局在と病原性2008
- Author(s)
  大槻均、金子修、Amporn Thongkukiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
- Organizer
  日本寄生虫学会大会
- Place of Presentation
  長崎市
- Year and Date
  2008-04-03
- Data Source
  KAKENHI-PROJECT-19790308
[Presentation] ネズミマラリア原虫の赤血球結合分子EBLの局在と病原生2008
- Author(s)
  大槻均、金子修、Ampom Thongku kiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
- Organizer
  日本寄生虫学会大会
- Place of Presentation
  長崎市
- Year and Date
  2008-04-03
- Data Source
  KAKENHI-PROJECT-19790308
[Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodium yoelii2008
- Author(s)
  Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M.
- Organizer
  19th Annual Molecular Parasitology Meeting
- Place of Presentation
  Woods Hole, USA
- Data Source
  KAKENHI-PROJECT-19390120
[Presentation] A complex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plasmodium falciparum2008
- Author(s)
  曹俊、金子修、Thongkukiatkul Amporn、橘真由美、大槻均、坪井敬文、鳥居本美
- Organizer
  第77回日本寄生虫学会大会
- Place of Presentation
  長崎市
- Data Source
  KAKENHI-PROJECT-19390120
[Presentation] ネズミマラリア原虫の赤血球結合分子相同体EBLの局在と病原性2008
- Author(s)
  大槻均、金子修、入子英幸、竹尾暁、坪井敬文、Thongkukiatkul Amporn、鳥居本美
- Organizer
  第77回日本寄生虫学会大会
- Place of Presentation
  長崎市
- Data Source
  KAKENHI-PROJECT-19390120
[Presentation] Plasmodium falciparum rhoptry neck protein (PfRON2) expressed at both erythrocytic and pre-erythrocytic invasive parasites2007
- Author(s)
  Cao J, Kaneko O, Thongkukiatkul A, Tachibana M , Otsuki H, Sattabongkot J, Tsuboi T, Torii M.
- Organizer
  The 7^<th> Awaji International Forum on Infection and Immunity
- Place of Presentation
  Awaji
- Data Source
  KAKENHI-PROJECT-19390120
[Presentation] A complex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plesmodium falciparum2007
- Author(s)
  Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Tsuboi T, Torii M.
- Organizer
  第6回分子寄生虫・マラリア研究フォーラム
- Place of Presentation
  松山
- Data Source
  KAKENHI-PROJECT-19390120
[Presentation] ネズミマラリア原虫赤血球侵入リガンドEBL領域3-5の機能解析
- Author(s)
  大槻　均,菅井千明,入子英幸,石野智子,金子　修,福本宗嗣,坪井敬文,鳥居本美
- Organizer
  第84回日本寄生虫学会本大会
- Place of Presentation
  杏林大学医学部（東京都三鷹市）
- Year and Date
  2015-03-21 – 2015-03-22
- Data Source
  KAKENHI-PROJECT-26460507

1. TORII Motomi (20164072)

# of Collaborated Projects: 3 results

# of Collaborated Products: 12 results
2. TSUBOI Takafumi (00188616)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
3. TAKEO Satoru (40302666)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. SAWASAKI Tatsuya (50314969)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TOMOKO Ishino (40402680)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. FUKUMOTO Soji (60111126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. IRIKO Hideyuki (60346674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. KANEKO Osamu (50325370)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. TACHIBANA Mayumi (00301325)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

OTSUKI Hitoshi 大槻 均

Otsuki Hitoshi 大槻 均

Research Projects

Research Products

Co-Researchers

Intracellular trafficking mechanism of erythrocyte invasion ligand molecule Plasmodium parasitesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

マラリア原虫赤血球侵入分子の細胞内輸送メカニズムの解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of RBC receptors against malaria parasite molecules in the merozoite apical organelle

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Screening of sporozoite receptor molecule(s) on hepatocytes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study of the effect of a recombinant immunosuppressive factor from parasites and immune-inhibitory mechanisms

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of erythrocyte proteins interacting with RhopH complex of malaria parasites

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Localization of erythrocyte invasion ligand defines virulence of Malaria parasitesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Association of the Plasmodium falciparuminfected erythrocyte surface molecule with ist virulence

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Plasmodium vivax gametocyte protein Pvs230 is a transmission-blocking vaccine candidate2012

Author(s)

Journal Title

Data Source

[Journal Article] N-terminal pro-domain of Pfs230 synthesized using cell-free system is sufficient to induce the complement dependent malaria transmission-blocking activity2011

Author(s)

Journal Title

Data Source

[Journal Article] Plasmodial ortholog of Toxoplasma gondii rhoptry neck protein 3 is localized to the rhoptry body2011

Author(s)

Journal Title

Data Source

[Journal Article] The wheat germ cell-free protein synthesis system : a key tool for novel malaria vaccine candidate discovery2010

Author(s)

Journal Title

Data Source

[Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009

Author(s)

Journal Title

NAID

Data Source

[Journal Article] A small-scale systematic analysis of alternative splicing in Plasmodium falciparum2009

OTSUKI Hitoshi 大槻均

Otsuki Hitoshi 大槻均