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OTSUKI Hitoshi  大槻 均

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Otsuki Hitoshi  大槻 均

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Researcher Number 80403806
Other IDs
Affiliation (Current) 2025: 鳥取大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2015 – 2016: 鳥取大学, 医学部, 准教授
2014: 鳥取大学, 医学部, 講師
2009 – 2011: 鳥取大学, 医学部, 講師
2007 – 2009: Ehime University, Graduate School of Medicine, Department of Molecular Parasitology, Assistant Professor
2006: 愛媛大学, 大学院医学系研究科, 助手
2005: 愛媛大学, 医学部, 助手
Review Section/Research Field
Principal Investigator
Parasitology (including Sanitary zoology) / Parasitology (including sanitary zoology)
Except Principal Investigator
Parasitology (including Sanitary zoology)
Keywords
Principal Investigator
赤血球侵入 / マラリア原虫 / 遺伝子組換え / マラリア / 細胞内輸送 / 遺伝子導入 / 侵入 / 病原性
Except Principal Investigator
感染症 / マラリア … More / 寄生虫 / レセプター / マラリア原虫 / 原虫 / Antigenic variation / Genetic polymorphism / Parasite / Infectious Disease / 抗原変異 / 遺伝子多型 / クローニング / 遺伝子発現抑制 / プレロセルコイド / 腹腔マクロフージ / 遺伝子組み換えタンパク / RACE法 / cDNA / 遺伝子組換えタンパク質 / alternative activation / 腹腔マクロファージ / peroxiredoxin / 遺伝子発 / 旋毛虫 / マクロファージ / 免疫抑制因子 / マンソン裂頭条虫 / 侵入 / マイクロネーム / 肝細胞侵入 / 細胞侵入 / スポロゾイト / バイオテクノロジー / ゲノム / コムギ胚芽無細胞タンパク質合成系 / 赤血球接着 Less
  • Research Projects

    (8 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (9 People)
  •  Intracellular trafficking mechanism of erythrocyte invasion ligand molecule Plasmodium parasitesPrincipal Investigator

    • Principal Investigator
      Otsuki Hitoshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Parasitology (including sanitary zoology)
    • Research Institution
      Tottori University
  •  マラリア原虫赤血球侵入分子の細胞内輸送メカニズムの解析Principal Investigator

    • Principal Investigator
      大槻 均
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Tottori University
  •  Identification of RBC receptors against malaria parasite molecules in the merozoite apical organelle

    • Principal Investigator
      TSUBOI Takafumi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Ehime University
  •  Screening of sporozoite receptor molecule(s) on hepatocytes

    • Principal Investigator
      TORII Motomi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Ehime University
  •  A study of the effect of a recombinant immunosuppressive factor from parasites and immune-inhibitory mechanisms

    • Principal Investigator
      FUKUMOTO Soji
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Tottori University
  •  Identification of erythrocyte proteins interacting with RhopH complex of malaria parasites

    • Principal Investigator
      TORII Motomi
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Ehime University
  •  Localization of erythrocyte invasion ligand defines virulence of Malaria parasitesPrincipal Investigator

    • Principal Investigator
      OTSUKI Hitoshi
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Ehime University
  •  Association of the Plasmodium falciparuminfected erythrocyte surface molecule with ist virulence

    • Principal Investigator
      KANEKO Osamu
    • Project Period (FY)
      2005 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Parasitology (including Sanitary zoology)
    • Research Institution
      Nagasaki University
      Ehime University

All 2017 2016 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Plasmodium vivax gametocyte protein Pvs230 is a transmission-blocking vaccine candidate2012

    • Author(s)
      Tachibana M, Sato C, Otsuki H, Sattabongkot J, Kaneko O, Torii M, Tsuboi T
    • Journal Title

      Vaccine

      Volume: 30 Pages: 1807-1812

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249028
  • [Journal Article] N-terminal pro-domain of Pfs230 synthesized using cell-free system is sufficient to induce the complement dependent malaria transmission-blocking activity2011

    • Author(s)
      Tachibana M, Wu Y, Iriko H, Muratova O, Macdonald NJ, Sattabongkot J, Takeo S, Otsuki H, Torii M, Tsuboi T
    • Journal Title

      Clin Vaccine Immunol

      Volume: 18 Pages: 1343-1350

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249028
  • [Journal Article] Plasmodial ortholog of Toxoplasma gondii rhoptry neck protein 3 is localized to the rhoptry body2011

    • Author(s)
      Ito D, Han ET, Takeo S, Thongkukiatkul A, Otsuki H, Torii M, Tsuboi T
    • Journal Title

      Parasitol Int

      Volume: 60 Pages: 132-138

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249028
  • [Journal Article] The wheat germ cell-free protein synthesis system : a key tool for novel malaria vaccine candidate discovery2010

    • Author(s)
      Tsuboi T, Takeo S, Arumugam TU, Otsuki H, Torii M
    • Journal Title

      Acta Trop

      Volume: 114 Pages: 171-176

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249028
  • [Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009

    • Author(s)
      Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M.
    • Journal Title

      Proc Natl Acad Sci (in press)(電子版)

    • NAID

      120006984096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009

    • Author(s)
      Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M
    • Journal Title

      Proc Natl Acad Sci USA

      Volume: 106 Pages: 7167-72

    • NAID

      120006984096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249028
  • [Journal Article] A small-scale systematic analysis of alternative splicing in Plasmodium falciparum2009

    • Author(s)
      Iriko H, Jin L, Kaneko O, Takeo S, Han ET, Tachibana M, Otsuki H, Torii M, Tsuboi T
    • Journal Title

      Parasitol Int

      Volume: 58 Pages: 196-9

    • NAID

      10027669225

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249028
  • [Journal Article] Single amino acid substitution in Plasmodiun yoelii erythrocyte ligand determinesits localization and controls parasite virulence.2009

    • Author(s)
      Otsuki H, Kaneko O, Thongkukiatkul. A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M
    • Journal Title

      Rroc Natl Acad Sci USA (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009

    • Author(s)
      大槻均、金子修、Amporn Thongkugiatkul、橘真由美、入子英幸、竹尾暁, 坪井敬文、鳥居本美
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America 電子版

      Pages: 1-6

    • NAID

      120006984096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790308
  • [Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009

    • Author(s)
      Otsuki H
    • Journal Title

      Proc Natl Acad Sci USA 106

      Pages: 7167-7172

    • NAID

      120006984096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249028
  • [Journal Article] Single amino acid substitution in Plasmodium yoelii erythrocyte ligand determines its localization and controls parasite virulence2009

    • Author(s)
      大槻均、金子修、Amporn Thongkukiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
    • Journal Title

      Proceedings of the National Academy of Sciences of the United States of America vol.106 no.17

      Pages: 7167-7172

    • NAID

      120006984096

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19790308
  • [Journal Article] Rhoptry neck protein RON2 forms a complex with microneme protein AMA1 in Plasmodium falciparum merozoites2009

    • Author(s)
      Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Gao Q, Tsuboi T, Torii M
    • Journal Title

      Parasitol Int

      Volume: 58 Pages: 29-35

    • NAID

      10025329950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21249028
  • [Presentation] マラリア原虫細胞内輸送ドメインのステージ特異性2017

    • Author(s)
      大槻 均ほか
    • Organizer
      第86回日本寄生虫学会大会
    • Place of Presentation
      北海道大学(北海道札幌市)
    • Year and Date
      2017-05-28
    • Data Source
      KAKENHI-PROJECT-26460507
  • [Presentation] ネズミマラリア原虫赤血球侵入リガンドEBL領域4の機能解析2016

    • Author(s)
      大槻 均,菅井千明,入子英幸,石野智子,金子 修,福本宗嗣,坪井敬文,鳥居本美
    • Organizer
      第85回日本寄生虫学会大会
    • Place of Presentation
      宮崎県宮崎市 宮崎市民プラザ
    • Year and Date
      2016-03-19
    • Data Source
      KAKENHI-PROJECT-26460507
  • [Presentation] 熱帯熱マラリア原虫rhoptry neck protein 3はAMA1非存在下でRON2およびRON4と複合体を形成する2011

    • Author(s)
      伊藤大輔、韓銀澤、竹尾暁、Thongkukiatkul Amporn、大槻均、鳥居本美、坪井敬文
    • Organizer
      第80回日本寄生虫学会
    • Place of Presentation
      東京都
    • Data Source
      KAKENHI-PROJECT-21390124
  • [Presentation] 旋毛虫の新生幼虫によるマウス腹腔マクロファージのAlternative activation2011

    • Author(s)
      井上菜菜瀬、福本宗嗣、大槻均、入子英幸
    • Organizer
      第80回日本寄生虫学会大会
    • Place of Presentation
      東京慈恵会医科大学(東京)
    • Year and Date
      2011-07-18
    • Data Source
      KAKENHI-PROJECT-21590464
  • [Presentation] 旋毛虫感染マウスにおける腹腔マクロファージのAlternative activation2010

    • Author(s)
      井上菜菜瀬、入子英幸、大槻均、福本宗嗣
    • Organizer
      第66回日本寄生虫学会西日本支部大会
    • Place of Presentation
      岡山大学(岡山市)
    • Year and Date
      2010-11-06
    • Data Source
      KAKENHI-PROJECT-21590464
  • [Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodium yoelii 43rd Annual2009

    • Author(s)
      大槻均、金子修、Amporn Thongkukiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
    • Organizer
      U.S.-Japan Joint Conference on Parasitic Diseases
    • Place of Presentation
      東京
    • Year and Date
      2009-01-07
    • Data Source
      KAKENHI-PROJECT-19790308
  • [Presentation] ErythrocyteBinding-Like molecule and Virulence of Plasmodium yoelii2009

    • Author(s)
      大槻均、金子修、Ampom Thongku kiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
    • Organizer
      43rd Annual U.S.-Japan Joint Conference on Parasitic Diseases
    • Place of Presentation
      東京
    • Year and Date
      2009-01-07
    • Data Source
      KAKENHI-PROJECT-19790308
  • [Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodiun yoelii.2008

    • Author(s)
      Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, TsuboiT, Torii M
    • Organizer
      19th Annual Molecular Parasitology Meeting
    • Place of Presentation
      Woods Hole, USA
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Presentation] A complex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plasmodium falciparum2008

    • Author(s)
      Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Tsuboi T, Torii M.
    • Organizer
      57^<th> ASTMH Annual Meeting, New Orleans
    • Place of Presentation
      USA
    • Year and Date
      2008-07-11
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodium yoelii Molecular Parasitology Meeting2008

    • Author(s)
      大槻均、金子修、Ampom Thongku kiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
    • Organizer
      Molecular Parasitology Meeting
    • Place of Presentation
      米国マサチューセッチュ州ウッズホール
    • Year and Date
      2008-09-21
    • Data Source
      KAKENHI-PROJECT-19790308
  • [Presentation] A ccmplex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plasmodium falciparum.2008

    • Author(s)
      曹俊, 金子修, Thongkukiatkul Amporn, 橘真由美, 大槻均, 坪井敬文, 鳥居本美
    • Organizer
      第77回日本寄生虫学会大会
    • Place of Presentation
      長崎市
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Presentation] A complex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plasmodium falciparuum.2008

    • Author(s)
      Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Tsuboi T, Torii M
    • Organizer
      57^<th> ASTMH Annual Meeting
    • Place of Presentation
      New Orleans, USA
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodium yoelii2008

    • Author(s)
      大槻均、金子修、Amporn Thongkukiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
    • Organizer
      Molecular Parasitology Meeting
    • Place of Presentation
      米国
    • Year and Date
      2008-09-21
    • Data Source
      KAKENHI-PROJECT-19790308
  • [Presentation] ネズミマラリア原虫の赤血球結合分子EBLの局在と病原性2008

    • Author(s)
      大槻均、金子修、Amporn Thongkukiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
    • Organizer
      日本寄生虫学会大会
    • Place of Presentation
      長崎市
    • Year and Date
      2008-04-03
    • Data Source
      KAKENHI-PROJECT-19790308
  • [Presentation] ネズミマラリア原虫の赤血球結合分子EBLの局在と病原生2008

    • Author(s)
      大槻均、金子修、Ampom Thongku kiatkul、橘真由美、入子英幸、竹尾暁、坪井敬文、鳥居本美
    • Organizer
      日本寄生虫学会大会
    • Place of Presentation
      長崎市
    • Year and Date
      2008-04-03
    • Data Source
      KAKENHI-PROJECT-19790308
  • [Presentation] Erythrocyte-Binding-Like molecule and Virulence of Plasmodium yoelii2008

    • Author(s)
      Otsuki H, Kaneko O, Thongkukiatkul A, Tachibana M, Iriko H, Takeo S, Tsuboi T, Torii M.
    • Organizer
      19th Annual Molecular Parasitology Meeting
    • Place of Presentation
      Woods Hole, USA
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Presentation] A complex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plasmodium falciparum2008

    • Author(s)
      曹俊、金子修、Thongkukiatkul Amporn、橘真由美、大槻均、坪井敬文、鳥居本美
    • Organizer
      第77回日本寄生虫学会大会
    • Place of Presentation
      長崎市
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Presentation] ネズミマラリア原虫の赤血球結合分子相同体EBLの局在と病原性2008

    • Author(s)
      大槻均、金子修、入子英幸、竹尾暁、坪井敬文、Thongkukiatkul Amporn、鳥居本美
    • Organizer
      第77回日本寄生虫学会大会
    • Place of Presentation
      長崎市
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Presentation] Plasmodium falciparum rhoptry neck protein (PfRON2) expressed at both erythrocytic and pre-erythrocytic invasive parasites2007

    • Author(s)
      Cao J, Kaneko O, Thongkukiatkul A, Tachibana M , Otsuki H, Sattabongkot J, Tsuboi T, Torii M.
    • Organizer
      The 7^<th> Awaji International Forum on Infection and Immunity
    • Place of Presentation
      Awaji
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Presentation] A complex formation of rhoptry neck protein 2 with a microneme protein, AMA1, in Plesmodium falciparum2007

    • Author(s)
      Cao J, Kaneko O, Thongkukiatkul A, Tachibana M, Otsuki H, Tsuboi T, Torii M.
    • Organizer
      第6回分子寄生虫・マラリア研究フォーラム
    • Place of Presentation
      松山
    • Data Source
      KAKENHI-PROJECT-19390120
  • [Presentation] ネズミマラリア原虫赤血球侵入リガンドEBL領域3-5の機能解析

    • Author(s)
      大槻 均,菅井千明,入子英幸,石野智子,金子 修,福本宗嗣,坪井敬文,鳥居本美
    • Organizer
      第84回日本寄生虫学会本大会
    • Place of Presentation
      杏林大学医学部(東京都三鷹市)
    • Year and Date
      2015-03-21 – 2015-03-22
    • Data Source
      KAKENHI-PROJECT-26460507
  • 1.  TORII Motomi (20164072)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 12 results
  • 2.  TSUBOI Takafumi (00188616)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 3.  TAKEO Satoru (40302666)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 4.  SAWASAKI Tatsuya (50314969)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  TOMOKO Ishino (40402680)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  FUKUMOTO Soji (60111126)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  IRIKO Hideyuki (60346674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  KANEKO Osamu (50325370)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  TACHIBANA Mayumi (00301325)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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