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IWAHORI SATOKO  岩堀 聡子

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IWAHORI Satoko  岩堀 聡子

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Researcher Number 80416164
Affiliation (Current) 2025: 藤田医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2021 – 2024: 藤田医科大学, 医学部, 講師
2018 – 2019: 藤田医科大学, 医学部, 講師
2005 – 2007: Aichi Cancer Center, Division of Virology, Research Resident, 腫瘍ウイルス学部, リサーチレジデント
2005: Aichi Cancer Center, Division of Virology, Research Resident, 腫瘍ウイルス学部, リサーチレジデント
Review Section/Research Field
Principal Investigator
Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 49060:Virology-related / 0803:Pathology, infection/immunology, and related fields
Except Principal Investigator
Biological Sciences / Virology
Keywords
Principal Investigator
DNAJA1 / HSP40 / リン酸化 / 低分子化合物C86 / サイトメガロウイルス / 分子シャペロン / NONO / 活性制御 / 基質 / キナーゼ基質 … More / 単純ヘルペスウイルス1型 / サイクリン依存性キナーゼ / UL97キナーゼ / ヒトサイトメガロウイルス / リン酸化基質 / EBV-PK / SF3B1 / MTA1 / 蛋白質分解 / キナーゼ / EBウイルス … More
Except Principal Investigator
MCM / p53 / ウイルスキナーゼ / リン酸化 / EBウイルス / EBV / ATM / Epstein-Barr virus / ユビキチン / ヘリカーゼ / 染色体複製 / CDK2 / ミスマッチ修復 / MCM複合体 / DNA損傷 / helicase / lytic infection / chromosomal DNA replication / protein kinase / phosphorylation / RB / DNAチェックポイント / DNA複製 / MDM2 / ubiquitilation / DNA damage / Epsyein-Barr virus / CDK阻害剤 / 溶解感染 / 潜伏感染 / E3リガーゼ Less
  • Research Projects

    (9 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (6 People)
  •  分子シャペロンHSP40を標的とした抗ウイルス戦略の基盤構築Principal Investigator

    • Principal Investigator
      岩堀 聡子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
    • Research Institution
      Fujita Health University
  •  Understanding the role and regulation of human cytomegalovirus UL97 kinasePrincipal Investigator

    • Principal Investigator
      岩堀 聡子
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49060:Virology-related
    • Research Institution
      Fujita Health University
  •  Identifying novel substrates of Epstein-Barr virus-encoded protein kinase (EBV-PK)Principal Investigator

    • Principal Investigator
      IWAHORI SATOKO
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0803:Pathology, infection/immunology, and related fields
    • Research Institution
      Fujita Health University
  •  ヘルペスウイルスの増殖機構解明と宿主細胞機能の利用

    • Principal Investigator
      鶴見 達也
    • Project Period (FY)
      2007 – 2008
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  EBウイルスBZLF1遺伝子産物によるp53機能抑制の分子機構

    • Principal Investigator
      鶴見 達也
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Host Cellular responses accompanied by Epstein-Barr Virus genome replication.

    • Principal Investigator
      TSURUMI Tatsuya
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Aichi Cancer Center Research Institute
  •  ヘルペス属ウイルス感染に伴う宿主染色体DNA合成停止の機構解析

    • Principal Investigator
      TSURUMI Tatsuya
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Exploratory Research
    • Research Field
      Virology
    • Research Institution
      Aichi Cancer Center Research Institute
  •  Latent and lytic replication of Epstein-Barr virus.

    • Principal Investigator
      TSURUMI Tatsuya
    • Project Period (FY)
      2004 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Aichi Cancer Center
  •  Host cellular functions supporting Epstein-Barr virus genome replication.

    • Principal Investigator
      TSURUMI Tatsuya
    • Project Period (FY)
      2003 – 2005
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Virology
    • Research Institution
      Aichi Cancer Center

All 2023 2022 2021 2019 2008 2007 2006

All Journal Article Presentation

  • [Journal Article] Serine 13 of the human cytomegalovirus viral cyclin-dependent kinase UL97 is required for regulatory protein 14-3-3 binding and UL97 stability2022

    • Author(s)
      S. Iwahori, A.C. Umana, R.F. Kalejta, and T. Murata
    • Journal Title

      J Biol Chem

      Volume: 298 Issue: 11 Pages: 102513-102513

    • DOI

      10.1016/j.jbc.2022.102513

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07046
  • [Journal Article] Noncanonical TATA Sequence in the UL44 Late Promoter of Human Cytomegalovirus is required for the accumulation of late viral transcripts.2008

    • Author(s)
      Isomura, H., Stinski, MF., Kudoh, A., Murata, T., Nakayama, S., Sato, Y., Iwahori, S. and Tsurumi, T.
    • Journal Title

      J virol. 82

      Pages: 1638-1646

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390147
  • [Journal Article] A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication.2008

    • Author(s)
      Isomura, H., Stinski, MF., Kudoh, A., Nakayama, S., Murata, T., Sato, Y., Iwahori, S. and Tsurumi, T.
    • Journal Title

      J Virol 82

      Pages: 849-858

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390147
  • [Journal Article] Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites.2008

    • Author(s)
      Iwahori S, et al.
    • Journal Title

      Cell Signal 20

      Pages: 1795-1803

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19041078
  • [Journal Article] Enhanced phosphorylation of transcription factor Sp1 dependent on Ataxia Telangiectasia-Mutated(ATM) in response to herpes simplex Vvrus Type I infection.2007

    • Author(s)
      Iwahori, S., Shirata, N., Kawaguchi, Y., Weller, SK., Sato., Y., Kudoh, A., Nakayama, S., Isomura, H. and Tsurumi T.
    • Journal Title

      J Virol 81

      Pages: 9653-9664

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390147
  • [Journal Article] The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesis.2007

    • Author(s)
      Isomura, H., Stinski, MF., Kudoh, A., Nakayama, S., Iwahori, S., Sato, Y. and Tsurumi, T.
    • Journal Title

      J Virol 81

      Pages: 6241-6247

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390147
  • [Journal Article] Enhanced phosphorylation of transcription factor Spl dependent on Ataxia Telangiectasia-Mutated(ATM)in response to herpes simplex Vvrus Type I infection.2007

    • Author(s)
      Iwahori S, et. al.
    • Journal Title

      J.Virol. 81

      Pages: 9653-9664

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18390147
  • [Journal Article] Postreplicative Mismatch Repair Factors are recruited to Epstein-Barr Virus Replication Compartments.2006

    • Author(s)
      Daikoku T, Kudoh A, Sugaya Y, Iwahori S. Shirata N, Isomura H and Tsurumi T.
    • Journal Title

      J Biol Chem. 281

      Pages: 11422-11430

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390147
  • [Journal Article] Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-6-7 complex during epstein-barr virus productive replication.2006

    • Author(s)
      Kudoh, A., Daikoku, T., Ishimi, Y., Kawaguchi, Y., Shirata, N., Iwahori. S., Isomura. H. and Tsurumi, T.
    • Journal Title

      J. Virol. 80

      Pages: 10064-10072

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390147
  • [Journal Article] Postreplicative Mismatch Repair Factors are recruited to Epstein-Barr Virus Replication2006

    • Author(s)
      Daikoku T, Kudoh A, Sugaya Y, Iwahori S, Shirata N, Isomura H, Tsurumi T.
    • Journal Title

      Compartments. J Biol Chem. 281

      Pages: 11422-11430

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16017322
  • [Journal Article] Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-6-7 Complex during Epstein-Barr Virus2006

    • Author(s)
      Ayumi Kudoh, Tohru Daikoku, Yukio Ishimi, Yasushi Kawaguchi, Noriko Shirata, Satoko Iwahori, Hiroki Isomura, Tatsuya Tsurumi.
    • Journal Title

      Productive Replication. J.ViroL 80

      Pages: 10064-10072

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-16017322
  • [Journal Article] Establishment of a novel foreign gene delivery system combining an HSV amplicon with an attenuated replication-competent virus, HSV-1 HF10.2006

    • Author(s)
      Zhang, L., Daikoku, T., Ohtake, K., Ohtsuka, J., Nawa, A., Kudoh, A., Iwahori, S., Isomura, H., Nishiyama, Y., and Tsurumi. T.
    • Journal Title

      J. Virol. Methods. 137

      Pages: 177-183

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390147
  • [Presentation] HSP40/DNAJ阻害剤C86がヒトサイトメガロウイルスの増殖に及ぼす影響(Inhibition of human cytomegalovirus infection by the HSP40/DNAJ inhibitor C86)2023

    • Author(s)
      岩堀聡子、村田貴之
    • Organizer
      第70回 日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07046
  • [Presentation] HSP40/DNAJ阻害剤C86がヒトサイトメガロウイルスの増殖に及ぼす影響2023

    • Author(s)
      岩堀聡子、村田貴之
    • Organizer
      第36回ヘルペスウイルス研究会
    • Data Source
      KAKENHI-PROJECT-21K07046
  • [Presentation] Serine 13 of the human cytomegalovirus viral cyclin dependent kinase UL97 is required for 14-3-3 binding and UL97 stability2022

    • Author(s)
      Robert F. Kalejta , Angie C. Umana, Takayuki Murata, Satoko Iwahori
    • Organizer
      6th Workshop on Emerging Issues in Oncogenic Virus Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K07046
  • [Presentation] ヒトサイトメガロウイルスUL97キナーゼの新規基質DNAJA1のウイルス増殖における役割2022

    • Author(s)
      岩堀聡子、村田貴之
    • Organizer
      第70回 日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07046
  • [Presentation] ヒトサイトメガロウイルスUL97キナーゼの新規基質DNAJA1の同定2022

    • Author(s)
      岩堀聡子、伴野愛奈、村田貴之
    • Organizer
      第54回 藤田医学会
    • Data Source
      KAKENHI-PROJECT-21K07046
  • [Presentation] ヒトサイトメガロウイルスUL97キナーゼの新規基質の探索2021

    • Author(s)
      伴野愛奈、岩堀聡子、村田貴之
    • Organizer
      第34回ヘルペスウイルス研究会
    • Data Source
      KAKENHI-PROJECT-21K07046
  • [Presentation] 14-3-3との相互作用を介したヒトサイトメガロウイルスUL97の蛋白質安定化2021

    • Author(s)
      岩堀聡子、Angie C. Umana、Robert F. Kalejta、村田貴之
    • Organizer
      第34回ヘルペスウイルス研究会
    • Data Source
      KAKENHI-PROJECT-21K07046
  • [Presentation] ヒトサイトメガロウイルスUL97キナーゼの新規基質DNAJA1の同定2021

    • Author(s)
      岩堀聡子、伴野愛奈、村田貴之
    • Organizer
      第68回日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-21K07046
  • [Presentation] ヒトサイトメガロウイルスUL97キナーゼは14-3-3ファミリーと相互作用する2019

    • Author(s)
      岩堀聡子、Angie C. Uman~a、Robert F. Kalejta、村田貴之
    • Organizer
      第33回ヘルペスウイルス研究会
    • Data Source
      KAKENHI-PROJECT-19K21264
  • [Presentation] Human Cytomegalovirus v-CDK UL97 interacts with 14-3-3 proteins.2019

    • Author(s)
      Satoko Iwahori, Angie C. Uman~a, Robert F. Kalejta, Takayuki Murata
    • Organizer
      44th annual International Herpesvirus Workshop
    • Data Source
      KAKENHI-PROJECT-19K21264
  • [Presentation] ヒトサイトメガロウイルスUL97キナーゼは14-3-3ファミリーと相互作用する2019

    • Author(s)
      岩堀聡子、村田貴之
    • Organizer
      第67回 日本ウイルス学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K21264
  • [Presentation] A cis-element downstream of TATA box in the HCMV major IE promoter stabilizes the TBP-TFIIB-DNA complex for efficient RNA transcription and splicing.2006

    • Author(s)
      Isomura H, Stinski MF, Kudoh A, Iwahori S, Shirata N, Daikoku T, Tsurumi T
    • Organizer
      31st Herpesvirus Workshop
    • Place of Presentation
      Seattle, USA
    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-18390147
  • 1.  TSURUMI Tatsuya (90172072)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 10 results
  • 2.  ISOMURA Hiroki (20294415)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 10 results
  • 3.  NAKAYAMA Sanae (80443456)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 4.  DAIKOKU Tohru (80291409)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 5.  SHIRATA Noriko (90416165)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 6.  菅谷 豊
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results

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