IWAHORI SATOKO 岩堀聡子

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IWAHORI Satoko 岩堀聡子

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Researcher Number	80416164
Affiliation (Current)	2025: 藤田医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 藤田医科大学, 医学部, 講師 2018 – 2019: 藤田医科大学, 医学部, 講師 2005 – 2007: Aichi Cancer Center, Division of Virology, Research Resident, 腫瘍ウイルス学部, リサーチレジデント 2005: Aichi Cancer Center, Division of Virology, Research Resident, 腫瘍ウイルス学部, リサーチレジデント
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 49060:Virology-related / 0803:Pathology, infection/immunology, and related fields Except Principal Investigator Biological Sciences / Virology
Keywords	Principal Investigator DNAJA1 / HSP40 / リン酸化 / 低分子化合物C86 / サイトメガロウイルス / 分子シャペロン / NONO / 活性制御 / 基質 / キナーゼ基質 … More / 単純ヘルペスウイルス1型 / サイクリン依存性キナーゼ / UL97キナーゼ / ヒトサイトメガロウイルス / リン酸化基質 / EBV-PK / SF3B1 / MTA1 / 蛋白質分解 / キナーゼ / EBウイルス … More Except Principal Investigator MCM / p53 / ウイルスキナーゼ / リン酸化 / EBウイルス / EBV / ATM / Epstein-Barr virus / ユビキチン / ヘリカーゼ / 染色体複製 / CDK2 / ミスマッチ修復 / MCM複合体 / DNA損傷 / helicase / lytic infection / chromosomal DNA replication / protein kinase / phosphorylation / RB / DNAチェックポイント / DNA複製 / MDM2 / ubiquitilation / DNA damage / Epsyein-Barr virus / CDK阻害剤 / 溶解感染 / 潜伏感染 / E3リガーゼ Less

分子シャペロンHSP40を標的とした抗ウイルス戦略の基盤構築Principal Investigator
- Principal Investigator
  
  岩堀聡子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Fujita Health University
Understanding the role and regulation of human cytomegalovirus UL97 kinasePrincipal Investigator
- Principal Investigator
  
  岩堀聡子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Fujita Health University
Identifying novel substrates of Epstein-Barr virus-encoded protein kinase (EBV-PK)Principal Investigator
- Principal Investigator
  
  IWAHORI SATOKO
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0803:Pathology, infection/immunology, and related fields
- Research Institution
  Fujita Health University
ヘルペスウイルスの増殖機構解明と宿主細胞機能の利用
- Principal Investigator
  
  鶴見達也
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Cancer Center Research Institute
EBウイルスBZLF1遺伝子産物によるp53機能抑制の分子機構
- Principal Investigator
  
  鶴見達也
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Cancer Center Research Institute
Host Cellular responses accompanied by Epstein-Barr Virus genome replication.
- Principal Investigator
  
  TSURUMI Tatsuya
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Aichi Cancer Center Research Institute
ヘルペス属ウイルス感染に伴う宿主染色体DNA合成停止の機構解析
- Principal Investigator
  
  TSURUMI Tatsuya
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Virology
- Research Institution
  Aichi Cancer Center Research Institute
Latent and lytic replication of Epstein-Barr virus.
- Principal Investigator
  
  TSURUMI Tatsuya
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Aichi Cancer Center
Host cellular functions supporting Epstein-Barr virus genome replication.
- Principal Investigator
  
  TSURUMI Tatsuya
- Project Period (FY)
  2003 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Aichi Cancer Center

All 2023 2022 2021 2019 2008 2007 2006

All Journal Article Presentation

[Journal Article] Serine 13 of the human cytomegalovirus viral cyclin-dependent kinase UL97 is required for regulatory protein 14-3-3 binding and UL97 stability2022
- Author(s)
  S. Iwahori, A.C. Umana, R.F. Kalejta, and T. Murata
- Journal Title
  
  J Biol Chem
  
  Volume: 298 Issue: 11 Pages: 102513-102513
- DOI
  10.1016/j.jbc.2022.102513
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07046
[Journal Article] Noncanonical TATA Sequence in the UL44 Late Promoter of Human Cytomegalovirus is required for the accumulation of late viral transcripts.2008
- Author(s)
  Isomura, H., Stinski, MF., Kudoh, A., Murata, T., Nakayama, S., Sato, Y., Iwahori, S. and Tsurumi, T.
- Journal Title
  
  J virol. 82
  
  Pages: 1638-1646
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390147
[Journal Article] A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication.2008
- Author(s)
  Isomura, H., Stinski, MF., Kudoh, A., Nakayama, S., Murata, T., Sato, Y., Iwahori, S. and Tsurumi, T.
- Journal Title
  
  J Virol 82
  
  Pages: 849-858
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390147
[Journal Article] Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites.2008
- Author(s)
  Iwahori S, et al.
- Journal Title
  
  Cell Signal 20
  
  Pages: 1795-1803
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19041078
[Journal Article] Enhanced phosphorylation of transcription factor Sp1 dependent on Ataxia Telangiectasia-Mutated(ATM) in response to herpes simplex Vvrus Type I infection.2007
- Author(s)
  Iwahori, S., Shirata, N., Kawaguchi, Y., Weller, SK., Sato., Y., Kudoh, A., Nakayama, S., Isomura, H. and Tsurumi T.
- Journal Title
  
  J Virol 81
  
  Pages: 9653-9664
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390147
[Journal Article] The late promoter of the human cytomegalovirus viral DNA polymerase processivity factor has an impact on delayed early and late viral gene products but not on viral DNA synthesis.2007
- Author(s)
  Isomura, H., Stinski, MF., Kudoh, A., Nakayama, S., Iwahori, S., Sato, Y. and Tsurumi, T.
- Journal Title
  
  J Virol 81
  
  Pages: 6241-6247
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390147
[Journal Article] Enhanced phosphorylation of transcription factor Spl dependent on Ataxia Telangiectasia-Mutated(ATM)in response to herpes simplex Vvrus Type I infection.2007
- Author(s)
  Iwahori S, et. al.
- Journal Title
  
  J.Virol. 81
  
  Pages: 9653-9664
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390147
[Journal Article] Postreplicative Mismatch Repair Factors are recruited to Epstein-Barr Virus Replication Compartments.2006
- Author(s)
  Daikoku T, Kudoh A, Sugaya Y, Iwahori S. Shirata N, Isomura H and Tsurumi T.
- Journal Title
  
  J Biol Chem. 281
  
  Pages: 11422-11430
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390147
[Journal Article] Phosphorylation of MCM4 at sites inactivating DNA helicase activity of the MCM4-6-7 complex during epstein-barr virus productive replication.2006
- Author(s)
  Kudoh, A., Daikoku, T., Ishimi, Y., Kawaguchi, Y., Shirata, N., Iwahori. S., Isomura. H. and Tsurumi, T.
- Journal Title
  
  J. Virol. 80
  
  Pages: 10064-10072
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390147
[Journal Article] Postreplicative Mismatch Repair Factors are recruited to Epstein-Barr Virus Replication2006
- Author(s)
  Daikoku T, Kudoh A, Sugaya Y, Iwahori S, Shirata N, Isomura H, Tsurumi T.
- Journal Title
  
  Compartments. J Biol Chem. 281
  
  Pages: 11422-11430
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017322
[Journal Article] Phosphorylation of MCM4 at Sites Inactivating DNA Helicase Activity of the MCM4-6-7 Complex during Epstein-Barr Virus2006
- Author(s)
  Ayumi Kudoh, Tohru Daikoku, Yukio Ishimi, Yasushi Kawaguchi, Noriko Shirata, Satoko Iwahori, Hiroki Isomura, Tatsuya Tsurumi.
- Journal Title
  
  Productive Replication. J.ViroL 80
  
  Pages: 10064-10072
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16017322
[Journal Article] Establishment of a novel foreign gene delivery system combining an HSV amplicon with an attenuated replication-competent virus, HSV-1 HF10.2006
- Author(s)
  Zhang, L., Daikoku, T., Ohtake, K., Ohtsuka, J., Nawa, A., Kudoh, A., Iwahori, S., Isomura, H., Nishiyama, Y., and Tsurumi. T.
- Journal Title
  
  J. Virol. Methods. 137
  
  Pages: 177-183
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390147
[Presentation] HSP40/DNAJ阻害剤C86がヒトサイトメガロウイルスの増殖に及ぼす影響（Inhibition of human cytomegalovirus infection by the HSP40/DNAJ inhibitor C86）2023
- Author(s)
  岩堀聡子、村田貴之
- Organizer
  第70回　日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07046
[Presentation] HSP40/DNAJ阻害剤C86がヒトサイトメガロウイルスの増殖に及ぼす影響2023
- Author(s)
  岩堀聡子、村田貴之
- Organizer
  第３6回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-21K07046
[Presentation] Serine 13 of the human cytomegalovirus viral cyclin dependent kinase UL97 is required for 14-3-3 binding and UL97 stability2022
- Author(s)
  Robert F. Kalejta , Angie C. Umana, Takayuki Murata, Satoko Iwahori
- Organizer
  6th Workshop on Emerging Issues in Oncogenic Virus Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07046
[Presentation] ヒトサイトメガロウイルスUL97キナーゼの新規基質DNAJA1のウイルス増殖における役割2022
- Author(s)
  岩堀聡子、村田貴之
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07046
[Presentation] ヒトサイトメガロウイルスUL97キナーゼの新規基質DNAJA1の同定2022
- Author(s)
  岩堀聡子、伴野愛奈、村田貴之
- Organizer
  第54回藤田医学会
- Data Source
  KAKENHI-PROJECT-21K07046
[Presentation] ヒトサイトメガロウイルスUL97キナーゼの新規基質の探索2021
- Author(s)
  伴野愛奈、岩堀聡子、村田貴之
- Organizer
  第34回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-21K07046
[Presentation] 14-3-3との相互作用を介したヒトサイトメガロウイルスUL97の蛋白質安定化2021
- Author(s)
  岩堀聡子、Angie C. Umana、Robert F. Kalejta、村田貴之
- Organizer
  第34回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-21K07046
[Presentation] ヒトサイトメガロウイルスUL97キナーゼの新規基質DNAJA1の同定2021
- Author(s)
  岩堀聡子、伴野愛奈、村田貴之
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07046
[Presentation] ヒトサイトメガロウイルスUL97キナーゼは14-3-3ファミリーと相互作用する2019
- Author(s)
  岩堀聡子、Angie C. Uman~a、Robert F. Kalejta、村田貴之
- Organizer
  第３３回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-19K21264
[Presentation] Human Cytomegalovirus v-CDK UL97 interacts with 14-3-3 proteins.2019
- Author(s)
  Satoko Iwahori, Angie C. Uman~a, Robert F. Kalejta, Takayuki Murata
- Organizer
  44th annual International Herpesvirus Workshop
- Data Source
  KAKENHI-PROJECT-19K21264
[Presentation] ヒトサイトメガロウイルスUL97キナーゼは14-3-3ファミリーと相互作用する2019
- Author(s)
  岩堀聡子、村田貴之
- Organizer
  第67回　日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-19K21264
[Presentation] A cis-element downstream of TATA box in the HCMV major IE promoter stabilizes the TBP-TFIIB-DNA complex for efficient RNA transcription and splicing.2006
- Author(s)
  Isomura H, Stinski MF, Kudoh A, Iwahori S, Shirata N, Daikoku T, Tsurumi T
- Organizer
  31st Herpesvirus Workshop
- Place of Presentation
  Seattle, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390147

1. TSURUMI Tatsuya (90172072)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
2. ISOMURA Hiroki (20294415)

# of Collaborated Projects: 6 results

# of Collaborated Products: 10 results
3. NAKAYAMA Sanae (80443456)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
4. DAIKOKU Tohru (80291409)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
5. SHIRATA Noriko (90416165)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
6. 菅谷豊

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results

IWAHORI SATOKO 岩堀 聡子

IWAHORI Satoko 岩堀 聡子

Research Projects

Research Products

Co-Researchers

分子シャペロンHSP40を標的とした抗ウイルス戦略の基盤構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Understanding the role and regulation of human cytomegalovirus UL97 kinasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identifying novel substrates of Epstein-Barr virus-encoded protein kinase (EBV-PK)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ヘルペスウイルスの増殖機構解明と宿主細胞機能の利用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

EBウイルスBZLF1遺伝子産物によるp53機能抑制の分子機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Host Cellular responses accompanied by Epstein-Barr Virus genome replication.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヘルペス属ウイルス感染に伴う宿主染色体DNA合成停止の機構解析

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Latent and lytic replication of Epstein-Barr virus.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Host cellular functions supporting Epstein-Barr virus genome replication.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Serine 13 of the human cytomegalovirus viral cyclin-dependent kinase UL97 is required for regulatory protein 14-3-3 binding and UL97 stability2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Noncanonical TATA Sequence in the UL44 Late Promoter of Human Cytomegalovirus is required for the accumulation of late viral transcripts.2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] A cis element between the TATA Box and the transcription start site of the major immediate-early promoter of human cytomegalovirus determines efficiency of viral replication.2008

Author(s)

Journal Title

Description

Data Source

[Journal Article] Identification of phosphorylation sites on transcription factor Sp1 in response to DNA damage and its accumulation at damaged sites.2008

Author(s)

Journal Title

Data Source

[Journal Article] Enhanced phosphorylation of transcription factor Sp1 dependent on Ataxia Telangiectasia-Mutated(ATM) in response to herpes simplex Vvrus Type I infection.2007

Author(s)

IWAHORI SATOKO 岩堀聡子

IWAHORI Satoko 岩堀聡子