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Wakita Hideaki  脇田 英明

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WAKITA Hideaki  脇田 英明

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Researcher Number 80416172
Other IDs
Affiliation (Current) 2025: 三重大学, 医学系研究科, 寄附講座教授
Affiliation (based on the past Project Information) *help 2022 – 2024: 三重大学, 医学系研究科, プロジェクト研究員
2018 – 2022: 藤田医科大学, 医学部, 教授
2014 – 2017: 藤田保健衛生大学, 医学部, 教授
2011: 藤田保健衛生大学, 医学部, 教授
2011: 藤田保健衛生大学, 医学部・内科, 教授
2010: 独立行政法人国立長寿医療研究センター, 加齢健康脳科学研究部, 室長
2009: National Institute for Longevity Sciences,NCGG, 血管性認知症研究部, 室長
Review Section/Research Field
Principal Investigator
Neurology / Basic Section 59010:Rehabilitation science-related / Basic Section 52020:Neurology-related
Except Principal Investigator
Basic Section 59010:Rehabilitation science-related / Rehabilitation science/Welfare engineering
Keywords
Principal Investigator
認知症 / 血管性認知症 / 神経分子病態学 / MRI / ドライビングシミュレータ / 自動車運転 / 軽度認知障害 / 慢性脳低灌流状態 / 大脳白質病変 / アディポカイン … More / 慢性脳低灌流 / ROCK / アルツハイマー型認知症 / LIM-kinase / Rho / 認知症モデル動物 / Rho-kinase / アルツハイマー病 / 発現制御 / 脳神経疾患 / 神経科学 / 炎症 / 脳血管障害 … More
Except Principal Investigator
神経可塑性 / リハビリテーション / 脳梗塞 / 分子機構 / 麻痺回復 / 薬剤投与 / 脳内分子機構 / 薬剤併用療法 / セロトニン / 機能回復 / 薬物併用療法 Less
  • Research Projects

    (8 results)
  • Research Products

    (32 results)
  • Co-Researchers

    (5 People)
  •  Development of a driving risk prediction index for people with mild cognitive impairment using a driving simulator and MRIPrincipal Investigator

    • Principal Investigator
      脇田 英明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Mie University
  •  Development of training and drug combination therapy based on molecular mechanisms in the brain involved in functional recovery after cerebral infarction

    • Principal Investigator
      水谷 謙明
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Fujita Health University
  •  Elucidation of changes in adipokine balance under chronic cerebral hypoperfusionPrincipal Investigator

    • Principal Investigator
      脇田 英明
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Mie University
      Fujita Health University
  •  Recovery of paralysis after cerebral infarction and analysis of molecular mechanisms based on O-GlcNAc modification in the brain

    • Principal Investigator
      Mizutani Kenmei
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Fujita Health University
  •  Post-translational modification-based molecular mechanisms in the brain involved in recovery of paralysis after cerebral infarction.

    • Principal Investigator
      Kenmei Mizutani
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Fujita Health University
  •  Analysis of the function of Rho-ROCK signal in dementia diseasePrincipal Investigator

    • Principal Investigator
      Wakita Hideaki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Fujita Health University
  •  Effectiveness of pharmacotherapy in stroke rehabilitation and identification of functional molecules implicated neuronal plasticity

    • Principal Investigator
      Mizutani Kenmei
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Fujita Health University
  •  An analysis of endothelial activation under cerebral ischemia using liposomes, which targets E-selectin.Principal Investigator

    • Principal Investigator
      WAKITA Hideaki
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Fujita Health University
      National Center for Geriatrics and Gerontology

All 2023 2021 2020 2019 2018 2017 2016 2015 2011 2010 2009

All Journal Article Presentation Book

  • [Book] モデル動物の作製と利用 循環器疾患2021 下巻2021

    • Author(s)
      脇田英明
    • Total Pages
      2
    • Publisher
      株式会社エル・アイ・シー
    • ISBN
      9784900487598
    • Data Source
      KAKENHI-PROJECT-21K07469
  • [Journal Article] Short-course remdesivir for healthcare-associated COVID-19: Case series from a non-acute care hospital.2023

    • Author(s)
      Takahashi Y, Wakita H, Ishihara T, Okazaki H, Ito A, Iwata M, Sonoda S, Doi Y
    • Journal Title

      Journal of Infection and Chemotherapy

      Volume: 29 Issue: 1 Pages: 95-97

    • DOI

      10.1016/j.jiac.2022.08.025

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07469
  • [Journal Article] Effects of exercise and bryostatin-1 on functional recovery and posttranslational modification in the perilesional cortex after cerebral infarction.2023

    • Author(s)
      Mizutani K, Sonoda S, Wakita H, Takahashi Y.
    • Journal Title

      Neuroreport

      Volume: 34 Issue: 5 Pages: 267-272

    • DOI

      10.1097/wnr.0000000000001887

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K11197
  • [Journal Article] Selective accumulation of adiponectin in the cerebral cortex under chronic cerebral hypoperfusion in the rat.2020

    • Author(s)
      Takahashi Y, Wakita H, Mizutani K, Watanabe A, Sonoda S, Tomimoto H.
    • Journal Title

      Neuroreport.

      Volume: 31 Issue: 2 Pages: 148-155

    • DOI

      10.1097/wnr.0000000000001391

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K01483, KAKENHI-PROJECT-21K07469
  • [Journal Article] Chronic cerebral hypoperfusion upregulates leptin receptor expression in astrocytes and tau phosphorylation in tau transgenic mice.2019

    • Author(s)
      Shimada T, Shindo A, Matsuyama H, Yata K, Niwa A, Sasaki R, Ayaki T, Maki T, Wakita H, Tomimoto H.
    • Journal Title

      Neuroscience Letters

      Volume: 704 Pages: 133-140

    • DOI

      10.1016/j.neulet.2019.04.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09684, KAKENHI-PROJECT-16K15246, KAKENHI-PROJECT-18K16557, KAKENHI-PROJECT-19K16277, KAKENHI-PROJECT-19H03572
  • [Journal Article] Review/Advances in Neurological Therapeutics (2016). Dementia2018

    • Author(s)
      脇田英明、冨本秀和
    • Journal Title

      Neurological Therapeutics

      Volume: 34 Issue: 5 Pages: 491-494

    • DOI

      10.15082/jsnt.34.5_491

    • NAID

      130006638892

    • ISSN
      0916-8443, 2189-7824
    • Language
      Japanese
    • Open Access
    • Data Source
      KAKENHI-PROJECT-16K09684
  • [Journal Article] Ritanserin, a serotonin-2 receptor antagonist, inhibits functional recovery after cerebral infarction.2018

    • Author(s)
      Mizutani K, Sonoda S, Wakita H
    • Journal Title

      NeuroReport

      Volume: 29 Issue: 1 Pages: 54-58

    • DOI

      10.1097/wnr.0000000000000930

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K09684, KAKENHI-PROJECT-17K01483
  • [Journal Article] Review/Advances in Neurological Therapeutics (2015). Dementia2017

    • Author(s)
      脇田英明、冨本秀和
    • Journal Title

      Neurological Therapeutics

      Volume: 33 Issue: 4 Pages: 506-509

    • DOI

      10.15082/jsnt.33.4_506

    • NAID

      130005398488

    • ISSN
      0916-8443, 2189-7824
    • Language
      Japanese
    • Open Access
    • Data Source
      KAKENHI-PROJECT-16K09684
  • [Journal Article] What is the Aftermath of Cerebral Microembolism?2017

    • Author(s)
      Wakita H, Shindo A, Tomimoto H
    • Journal Title

      Journal of Alzheimer’s Disease & Parkinsonism

      Volume: 7 Issue: 5 Pages: 375-375

    • DOI

      10.4172/2161-0460.1000375

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K09684
  • [Journal Article] Effects of exercise and bryostatin-1 on serotonin dynamics after cerebral infarction2016

    • Author(s)
      Mizutani K, Sonoda S, Wakita H, Okazaki H, Katoh Y, Chihara T, Shimpo K.
    • Journal Title

      NeuroReport

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26350596
  • [Journal Article] Effects of exercise and bryostatin-1 on serotonin dynamics after cerebral infarction.2016

    • Author(s)
      Mizutani K, Sonoda S, Wakita H, Okazaki H, Katoh Y, Chihara T, Shimpo K.
    • Journal Title

      Neuroreport

      Volume: 27 Issue: 9 Pages: 659-664

    • DOI

      10.1097/wnr.0000000000000592

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26350596, KAKENHI-PROJECT-16K09684
  • [Journal Article] Protein kinase C activator, bryostatin-1, promotes exercise-dependent functional recovery in rats with cerebral infarction2015

    • Author(s)
      Mizutani K, Sonoda S, Wakita H, Shimpo K
    • Journal Title

      Am J Phys Med Rehabil

      Volume: 94 Issue: 3 Pages: 239-243

    • DOI

      10.1097/phm.0000000000000227

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26350596
  • [Journal Article] Watershed Infarcts in a multiple microembolic model of monkey2011

    • Author(s)
      Maki T, Wakita H, Mase M, Itagaki I, Saito N, Ono F, Adachi K, Ito H, Takahashi R, Ihara M, Tomimoto H
    • Journal Title

      Neuroscience Letters

      Volume: 499 Issue: 2 Pages: 80-83

    • DOI

      10.1016/j.neulet.2011.05.036

    • NAID

      120003238944

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21500336, KAKENHI-PROJECT-21591106, KAKENHI-PROJECT-23390233, KAKENHI-PROJECT-23650182
  • [Journal Article] Dental pulp derived CD31-/CD146-side population stem/progenitor cells enhance recovery of focal cerebral ischemia in rats2011

    • Author(s)
      Sugiyama M, Iohara K, Wakita H, Hattori H, Ueda M, Matsushita K, Nakashima M
    • Journal Title

      Tissue Engineering Part A

      Volume: 17(9-10) Issue: 9-10 Pages: 1303-1311

    • DOI

      10.1089/ten.tea.2010.0306

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591106, KAKENHI-PROJECT-21659436, KAKENHI-PROJECT-22390354
  • [Journal Article] E-selectin targeting to visualize tumors in vivo.2010

    • Author(s)
      Hirai M, Hiramatsu Y, Iwashita S, Otani T, Chen L, Li Y G, Okada M, Oie K, Igarashi K, Wakita H, Seno M
    • Journal Title

      Contrast Media & Molecular Imaging

      Volume: VOL.5 Pages: 70-77

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591106
  • [Journal Article] E-selectin targeting to visualize tumors in vivo2010

    • Author(s)
      Hirai M, Hiramatsu Y, Iwashita S, Otani T, Chen L, Li YG, Okada M, Oie K, Igarashi K, Wakita H, Seno M
    • Journal Title

      Contrast Media & Molecular Imaging

      Volume: 5(2) Issue: 2 Pages: 70-77

    • DOI

      10.1002/cmmi.367

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591106
  • [Journal Article] miRNAによるE-selectinの抑制2010

    • Author(s)
      吉崎嘉一、脇田英明、大隅典子、高橋慶吉
    • Journal Title

      炎症と免疫

      Volume: 18(2) Pages: 130-134

    • Data Source
      KAKENHI-PROJECT-21591106
  • [Presentation] 脳梗塞モデルラットの訓練による脳内変化と薬剤投与の有効性2023

    • Author(s)
      水谷謙明、園田茂、脇田英明、高橋雄
    • Organizer
      第128回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-20K11197
  • [Presentation] 脳梗塞モデルラットへの訓練効果と脳内リン酸化プロテオーム解析による分子機構の解明2021

    • Author(s)
      水谷謙明 園田茂 脇田英明
    • Organizer
      第127回日本解剖学会
    • Data Source
      KAKENHI-PROJECT-17K01483
  • [Presentation] 脳梗塞ラットへの訓練効果と脳内リン酸化プロテオーム解析による分子機構の解明2021

    • Author(s)
      水谷謙明 園田茂 脇田英明
    • Organizer
      第127回日本解剖学会
    • Data Source
      KAKENHI-PROJECT-20K11197
  • [Presentation] 脳梗塞ラットへの訓練・薬剤併用療法の効果と脳内分子機構について2019

    • Author(s)
      水谷謙明、園田 茂、脇田英明
    • Organizer
      Brain and Rehabilitation 2019 ・第26回脳機能とリハビリテーション研究会学術集会
    • Data Source
      KAKENHI-PROJECT-17K01483
  • [Presentation] 脳梗塞ラットへの訓練・薬剤併用療法と脳内リン酸化タンパクの変動2019

    • Author(s)
      水谷謙明、園田 茂、脇田英明
    • Organizer
      第124回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17K01483
  • [Presentation] 脳梗塞ラットにおける訓練効果と脳内セロトニンの役割2018

    • Author(s)
      水谷 謙明、園田 茂、脇田英明
    • Organizer
      第123回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17K01483
  • [Presentation] Spatial and temporal distribution of adiponectin in the rat brain under chronic cerebral hypoperfusion.2017

    • Author(s)
      Takahashi Y, Wakita H, Mizutani K, Sonoda S, Tomimoto H
    • Organizer
      XXIII World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09684
  • [Presentation] Driving performance in patients with Alzheimer’s disease, Dementia with Lewy Bodies, and mild cognitive impairment.2017

    • Author(s)
      Wakita H, Takahashi Y, Masuzugawa S, Ito K, Miyasaka H, Sonoda S, Tomimoto H
    • Organizer
      XXIII World Congress of Neurology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09684
  • [Presentation] ドライビングシュミレーターを用いた認知症患者の自動車運転特性の解析2017

    • Author(s)
      高橋雄,宮坂裕之, 園田茂, 真鈴川聡, 冨本秀和, 脇田英明
    • Organizer
      第59回日本老年医学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K09684
  • [Presentation] E-selectinを標的としたリポソームによる細胞接着分子阻止とグリア細胞活性化の抑制2011

    • Author(s)
      脇田英明、足立香代、丸山和佳子
    • Organizer
      第52回日本神経学会学術大会
    • Place of Presentation
      名古屋
    • Year and Date
      2011-05-19
    • Data Source
      KAKENHI-PROJECT-21591106
  • [Presentation] 血管性認知症の実験モデル(シンポジウム1,血管性認知症のニューホライズン)2010

    • Author(s)
      脇田英明
    • Organizer
      第29回日本認知症学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-11-05
    • Data Source
      KAKENHI-PROJECT-21591106
  • [Presentation] セレクチンを標的としたリポソームによる細胞接着分子抑制効果の検討2010

    • Author(s)
      脇田英明、足立香代
    • Organizer
      第35回日本脳卒中学会総会
    • Place of Presentation
      盛岡
    • Year and Date
      2010-04-16
    • Data Source
      KAKENHI-PROJECT-21591106
  • [Presentation] E-selectinを標的としたリポソームによる細胞接着分子阻止とグリア細胞活性化の抑制2010

    • Author(s)
      脇田英明、足立香代
    • Organizer
      第51回日本神経学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-05-22
    • Data Source
      KAKENHI-PROJECT-21591106
  • [Presentation] マウス血管性認知症モデルに対するSialyl Lewis X結合リポソームの有効性の検討2010

    • Author(s)
      脇田英明、足立香代、武田和也、國本正子、渡邉淳、丸山和佳子
    • Organizer
      第29回日本認知症学会学術集会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-21591106
  • [Presentation] マウス血管性認知症モデル白質病変での細胞接着分子発現とグリア細胞活性化の検討2009

    • Author(s)
      脇田英明、吉崎嘉一
    • Organizer
      第50回日本神経学会総会
    • Place of Presentation
      仙台
    • Year and Date
      2009-05-22
    • Data Source
      KAKENHI-PROJECT-21591106
  • 1.  Mizutani Kenmei (30351068)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 13 results
  • 2.  園田 茂 (10197022)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 3.  高橋 雄 (50770012)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  高橋 良輔
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  伊東 秀文
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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