SAKAKIBARA Tomohiro 榊原智博

Researcher Number	80422111
Affiliation *help	2014 : 東北労災病院, 副部長 2011 – 2013 : 東北大学, 大学病院, 助教 2007 – 2012 : Tohoku University, 病院, 助教
Review Section/Research Field	Principal Investigator Respiratory organ internal medicine Except Principal Investigator Respiratory organ internal medicine
Keywords	Principal Investigator 非結核性抗酸菌症 / SLPI / プロテオーム / 非閉塞性肺疾患 / ピルフェニドン / 結合タンパク質 / 肺線維症 / 結合蛋白質 / 抗体 / 微生物 … More Except Principal Investigator EGFR遺伝子変 / 東アジア / EGFR受容体 / ゲノム / EGF受容体 / 家族性癌 / エクソーム解析 / 肺腺癌 / ゲノム解析研究 / 非喫煙者 Less

CpGDNA配列に着目した非結核性抗酸菌症の病態解明と新規治療法の開発Principal Investigator
- Principal Investigator
  
  榊原智博
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Familial pathogenesis of lung cancer with the epidermal growth factor receptor (EGFR) gene mutation
- Principal Investigator
  
  KIKUCHI Toshiaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Identification of the pirfenidone targeting moleculePrincipal Investigator
- Principal Investigator
  
  SAKAKIBARA Tomohiro
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Biological background for non-smoker lung adenocarcinoma : Why do EGFR somatic mutations accumulate on lung adenocarcinoma and on Asian ethnics?
- Principal Investigator
  
  NUKIWA Toshihiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Identification of the hot tub lung antigen and the molecular analysis of its mechanismPrincipal Investigator
- Principal Investigator
  
  SAKAKIBARA Tomohiro
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University
Molecular analysls of transcriptional function of SLPIPrincipal Investigator
- Principal Investigator
  
  SAKAKIBARA Tomohiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku University

All 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Randomized Phase II Trial Comparing Carboplatin Plus Weekly Paclitaxel and Docetaxel Alone in Elderly Patients With Advanced Non-Small Cell Lung Cancer: North Japan Lung Cancer Group Trial 0801.2014
- Author(s)
  Maemondo M, Inoue A, Sugawara S, Harada T, Minegishi Y, Usui K, Miwa K, Morikawa N, Kambe M, Ube K, Watanabe K, Ishimoto O, Sakakibara T, Gemma A, Nukiwa T
- Journal Title
  
  Oncologist
  
  Volume : 19 Pages : 352-353
- DOI
  10.1634/theoncologist.2013-0411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591184, KAKENHI-PROJECT-25461145, KAKENHI-PROJECT-25461172
[Journal Article] Randomized phase II trial of uracil/tegafur and cisplatin versus vinorelbine and cisplatin with concurrent thoracic radiotherapy for locally advanced unresectable stage III non-small-cell lung cancer2013
- Author(s)
  Sugawara S, Maemondo M, Tachihara M, Inoue A, Ishimoto O, Sakakibara T, 全14名中6番目
- Journal Title
  
  Ｌｕｎｇ　Ｃａｎｃｅｒ
  
  Volume : ８１ Pages : 1-1
- DOI
  10.1016/j.lungcan.2013.04.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790893, KAKENHI-PROJECT-24659396, KAKENHI-PROJECT-25461145
[Journal Article] A phase II study of irinotecan as a third- or fourth-line treatment for advanced non-small cell lung cancer:NJLCG07032013
- Author(s)
  Matsubara M
- Journal Title
  
  Respir Investig
  
  Volume : 51 Pages : 28-34
- DOI
  10.1016/j.resinv.2012.09.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790893
[Journal Article] An effective enrichment strategy for EML4-ALK fusion gene screening in patients with non-small cell lung cancer.2013
- Author(s)
  Kobayashi M, Sakakibara T, Inoue A, Fukuhara T, Sasano H, Ichinose M, Nukiwa T.
- Journal Title
  
  Respir Investig
  
  Volume : ５２ Pages : 49-56
- DOI
  10.1016/j.resinv.2013.06.003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461145
[Journal Article] Complicated secondary pneumonia after swine-origin influenza A virus infection in an immunocompetent patient2012
- Author(s)
  Igusa R, Sakakibara T,
- Journal Title
  
  Tohoku J Exp Med
  
  Volume : 226 Pages : 117-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790893
[Journal Article] Bilateral peripheral infiltrates refractory to immunosuppressants were diagnosed as autoimmune pulmonary alveolar proteinosis and improved by inhalation of granulocyte/macrophage-colony stimulating factor2012
- Author(s)
  Satoh H, Tazawa R, Sakakibara T,
- Journal Title
  
  Intern Med
  
  Volume : 51 Pages : 1737-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790893
[Journal Article] 新型インフルエンザに罹患した健常者成人発症した二次性肺炎2012
- Author(s)
  井草龍太郎、榊原智博、柴原泰三ほか
- Journal Title
  
  Tohoku J Exp Med.
  
  Volume : 226 Pages : 117-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790893
[Journal Article] Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+CD11c+cells2011
- Author(s)
  大東久佳、榊原智博, 他14名
- Journal Title
  
  Eur Respir J.
  
  Volume : (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790760
[Journal Article] Mycobacterial hypersensitivity pneumonitis requires TLR9. MyD88 in lung CD11b+ CD11c+ cells2011
- Author(s)
  Daito H, Kikuchi T, Sakakibara T, Gomi K, Damayanti T, Zaini J, Tode N, Kanehira M, Koyama S, Fujimura S, Ebina M, Ishii KJ, Akira S, Takai T, Watanabe A, Nukiwa T
- Journal Title
  
  Eur. Respir. J
  
  Volume : 38 Pages : 688-701
- DOI
  10.1183/09031936.00177110
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249052, KAKENHI-PROJECT-22659057, KAKENHI-PROJECT-23390219
[Journal Article] Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+CD11c+ cells.2011
- Author(s)
  Daito H, Kikuchi T, Sakakibara T
- Journal Title
  
  Eur Respir J. 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790760
[Journal Article] Randamized phase II trial of weekly paclitaxel combined with carboplatin versus standard paclitaxel combined with carboplatin for elderly patients with advanced non-small-cell lung cancer2010
- Author(s)
  Sakakibara T, Inoue A, Sugawara, et al
- Journal Title
  
  Ann Oncol 4
  
  Pages : 800-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249052
[Journal Article] Randomized phase II trial of weekly paclitaxel combined with carboplatin versus standard paclitaxel combined with carboplatin for eldely patients with advanced non-small-cell lung cancer2010
- Author(s)
  Sakakibara T, Inoue A, Sugawara S, Maemondo M, Ishida T, Usui K, Abe T, Kanbe M, Watanabe H, Saijo Y, Nukiwa T
- Journal Title
  
  Ann Oncol
  
  Volume : 27 Pages : 795-799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249052
[Journal Article] Association between mycobacterial genotypes and disease progression in Mycobacterium avium pulmonary infection2009
- Author(s)
  菊地利明、榊原智博, 他11名
- Journal Title
  
  Thorax 64
  
  Pages : 901-907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790760
[Journal Article] Association between mycobacterial genotypes and disease progression in Mycobacterium avium pulmonary infection.2009
- Author(s)
  Kikuchi T, Watanabe A, Gomi K, Sakakibara T
- Journal Title
  
  Thorax. 64(10)
  
  Pages : 901-907
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790760
[Journal Article] Randomized phaseIItrial of weekly paclitaxel combined with carboplatin versus standard paclitaxel combined with calboplatin for elderly patients with advanced non-small-cell lung cancer2009
- Author(s)
  Sakakibara T, Inoue A, Sugawara S, Maemondo M, Ishida T, Usui K, Abe T, Kanbe M, Watanabe H, Saijo Y, Nukiwa T
- Journal Title
  
  Ann Oncol
  
  Volume : 21 Pages : 795-799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249052
[Journal Article] Successful treatment of carcinomatous meningitis with gefitinib in a patient with lung adenocarcinoma harboring a mutated EGF receptor gene2008
- Author(s)
  福原達朗、榊原智博、ほか6名
- Journal Title
  
  Tohoku J Exp Med 4月号
  
  Pages : 359-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790554
[Journal Article] Adenocarcinoma With Epidermal Growth Factor Receptor Gene Mutations in Three Siblings2008
- Author(s)
  榊原智博, 他7名
- Journal Title
  
  Journal of Thoracic Oncology 3
  
  Pages : 311-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790554
[Journal Article] Adenocarcinoma With Epidermal Growth Factor Receptor Gene Mutations in Three Siblings2008
- Author(s)
  榊原智博、ほか7名
- Journal Title
  
  Journal of Thoracic Oncology 3月号
  
  Pages : 311-313
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790554
[Journal Article] Successful treatment of carcinomatous meningitis with gefitinib in a pat ient with lung adenocarcinoma harboring a mutated EGF receptor gene2008
- Author(s)
  福原達朗、榊原智博, 他6名
- Journal Title
  
  Tohoku J Exp Med 214
  
  Pages : 359-363
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790554
[Presentation] EGFR遺伝子変異を伴う家族性肺腺癌患者におけるエクソーム解析2013
- Author(s)
  東出直樹、菊地利明、榊原智博、齋藤良太、光石陽一郎、大河内眞也、井上彰、一ノ瀬正和
- Organizer
  第７２回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25461145
[Presentation] 多型縦列反復配列（VNTR）を用いた菌ゲノム解析による非結核性抗酸菌症の治療反応性予測2013
- Author(s)
  菊地利明、榊原智博、玉田勉、小橋吉博、福原達朗、大河内眞也、貫和敏博、渡辺彰、一ノ瀬正和
- Organizer
  第110回日本内科学会講演会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24659399
[Presentation] EGFR遺伝子変異を伴う肺腺癌患者における遺伝学的機序の解析2012
- Author(s)
  東出直樹、菊地利明、榊原智博、一ノ瀬正和
- Organizer
  第52回日本呼吸器学会学術講演会
- Place of Presentation
  神戸
- Year and Date
  2012-04-22
- Data Source
  KAKENHI-PROJECT-23790893
[Presentation] Whole-exome sequencing of familial non-small cell lung cancer patients with the EGFR genemutaions2012
- Author(s)
  東出直樹、菊地利明、榊原智博、一ノ瀬正和
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  札幌
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-23790893
[Presentation] Clinical Aspects Of Non-Small Cell Lung Cancer Harboring EML4-ALK Fusion Gene In Tohoku University Hospital2011
- Author(s)
  Sakakibara T, Inoue A, Fukuhara T, Sasaki T, Nukiwa T
- Organizer
  American Thoracic Society International Conference
- Place of Presentation
  Denver
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-21249052
[Presentation] III期局所進行切除不能非小細胞肺癌に対するCDDP+ UFT(UP)とCDDP+ VNR(NP)併用化学放射線療法の無作為化比較第二相試験2011
- Author(s)
  臼井一裕, 菅原俊一, 前門戸任, 石田卓, 榊原智博, 井上彰, 石本修, 松原信行, 西條康夫, 貫和敏博
- Organizer
  第51回日本呼吸器学会学術講演会
- Place of Presentation
  東京
- Year and Date
  2011-04-24
- Data Source
  KAKENHI-PROJECT-21249052
[Presentation] 東北大学病院におけるEML4ALK融合遺伝子陽2011
- Author(s)
  小林誠、榊原智博、井上彰、福原達朗、貫和敏博
- Organizer
  第52回日本肺癌学会総会
- Place of Presentation
  大阪
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-23790893
[Presentation] 東北大学病院におけるEML4-ALK融合遺伝子陽性肺癌の臨床的特徴2011
- Author(s)
  小林誠、榊原智博、井上彰、貫和敏博
- Organizer
  第52回日本肺癌学会
- Place of Presentation
  大阪、日本
- Year and Date
  2011-11-03
- Data Source
  KAKENHI-PROJECT-21249052
[Presentation] 切除不能局所進行非小細胞肺癌の化学放射線療法におけるUFT+ CDDP対VNR+ CDDPの無作為化比較第二相試験2010
- Author(s)
  榊原智博, 菅原俊一, 前門戸任, 石田卓, 臼井一裕, 井上彰, 石本修, 松原信行, 西條康夫, 貫和敏博
- Organizer
  第51回日本肺癌学会
- Place of Presentation
  広島
- Year and Date
  2010-11-03
- Data Source
  KAKENHI-PROJECT-21249052
[Presentation] プラセナ併用療法後の二次化学療法におけるS-1と隔週ドセタキセル併用療法の第二相試験2009
- Author(s)
  榊原智博, 井上彰, 石本修, 前門戸任, 松原信行, 森川直人, 奥寺弘一, 臼井一裕, 鈴木俊郎, 貫和敏博, 菅原俊一
- Organizer
  第50回日本肺癌学会
- Place of Presentation
  東京
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-21249052
[Presentation] 東北大学病院におけるEML4ALK 融合遺伝子陽
- Author(s)
  小林誠、榊原智博、井上彰、福原達朗、貫和敏博
- Organizer
  第５２回日本肺癌学会総会
- Place of Presentation
  大阪、日本
- Data Source
  KAKENHI-PROJECT-23790893

1. KIKUCHI Toshiaki (10280926)

# of Collaborated Projects : 4results

# of Collaborated Products : 6results
2. INOUE Akira (70361087)

# of Collaborated Projects : 2results

# of Collaborated Products : 8results
3. NUKIWA Toshihiro (40129036)

# of Collaborated Projects : 1results

# of Collaborated Products : 8results
4. EBINA Masahito (10280885)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
5. FUKUHARA Tatsurou (80400365)

# of Collaborated Projects : 1results

# of Collaborated Products : 1results
6. HAGIWARA Kouichi (00240705)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
7. MATSUBARA Yoichi (00209602)

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
8. DAITO Hisayoshi

# of Collaborated Projects : 1results

# of Collaborated Products : 2results
9. TODE Naoki

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
10. HIRANO Taizou

# of Collaborated Projects : 1results

# of Collaborated Products : 0results
11. 高井俊行

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
12. 西條康夫

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
13. 前門戸任

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
14. 弦間昭彦

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

SAKAKIBARA Tomohiro 榊原 智博

Research Projects

Research Products

Co-Researchers

CpGDNA配列に着目した非結核性抗酸菌症の病態解明と新規治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Familial pathogenesis of lung cancer with the epidermal growth factor receptor (EGFR) gene mutation

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of the pirfenidone targeting moleculePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Biological background for non-smoker lung adenocarcinoma : Why do EGFR somatic mutations accumulate on lung adenocarcinoma and on Asian ethnics?

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of the hot tub lung antigen and the molecular analysis of its mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysls of transcriptional function of SLPIPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Randomized Phase II Trial Comparing Carboplatin Plus Weekly Paclitaxel and Docetaxel Alone in Elderly Patients With Advanced Non-Small Cell Lung Cancer: North Japan Lung Cancer Group Trial 0801.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Randomized phase II trial of uracil/tegafur and cisplatin versus vinorelbine and cisplatin with concurrent thoracic radiotherapy for locally advanced unresectable stage III non-small-cell lung cancer2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A phase II study of irinotecan as a third- or fourth-line treatment for advanced non-small cell lung cancer:NJLCG07032013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An effective enrichment strategy for EML4-ALK fusion gene screening in patients with non-small cell lung cancer.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Complicated secondary pneumonia after swine-origin influenza A virus infection in an immunocompetent patient2012

Author(s)

Journal Title

Data Source

[Journal Article] Bilateral peripheral infiltrates refractory to immunosuppressants were diagnosed as autoimmune pulmonary alveolar proteinosis and improved by inhalation of granulocyte/macrophage-colony stimulating factor2012

Author(s)

Journal Title

Data Source

[Journal Article] 新型インフルエンザに罹患した健常者成人発症した二次性肺炎2012

Author(s)

Journal Title

Data Source

[Journal Article] Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+CD11c+cells2011

Author(s)

Journal Title

Data Source

[Journal Article] Mycobacterial hypersensitivity pneumonitis requires TLR9. MyD88 in lung CD11b+ CD11c+ cells2011

Author(s)

Journal Title

DOI

SAKAKIBARA Tomohiro 榊原智博

[Presentation] 多型縦列反復配列（VNTR）を用いた菌ゲノム解析による非結核性抗酸菌症の治療反応性予測2013