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SAITO Ayako  齋藤 綾子

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齋藤 綾子  サイトウ アヤコ

SAITOU Ayako  斎藤 綾子

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Researcher Number 80424109
Affiliation (Current) 2025: 杏林大学, 医学部, その他
Affiliation (based on the past Project Information) *help 2018: 杏林大学, 医学部, 実験助手
2014 – 2015: 杏林大学, 医学部, 実験助手
2010: 杏林大学, 医学部・その他
2009: 杏林大学, 医学部, 実験助手
2007: 杏林大学, 医学部, 実験助手
Review Section/Research Field
Except Principal Investigator
Neurochemistry/Neuropharmacology / Neurochemistry/Neuropharmacology / Neurophysiology and muscle physiology
Keywords
Except Principal Investigator
神経科学 / 開口放出 / グリア細胞 / syntaxin / 脳・神経 / syntaxin1A / syntaxin1B / 遺伝子ノックアウトマウス / シンタキシン1B / シンタキシン1A … More / シナプス伝達 / 神経栄養因子 / トランスポーター / 神経伝達物質 / シンタキシン1 / 細胞死 / SNARE / オートファジー / アルツハイマー / ERストレス / ノックアウトマウス / 神経成長因子 / シンタキシン1B / haploid / 自閉性障害 / 遅い神経伝達物質放出過程 / 速い神経伝達物質放出過程 / シンタキシン1B / シンタキシン1A / BDNF / 機能分化 / 神経伝達 / vesicle transport / Golgi / ER-stress / 脳神経疾患 / ストレス / 疾患モデル / 自閉症 / シンタキシン1 / 運動障害 / 痙攣発作 / 致死 / 遅い神経伝達 / 速い神経伝達 / 行動異常 / シナプス伝達制御因子 / シナプス機能分化 / 疾患モデル動物 / ノックアウトマウス自閉性障害 Less
  • Research Projects

    (5 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (7 People)
  •  Role of syntaxin1 in glial cells on the interaction between neurons and glial cells

    • Principal Investigator
      Kofuji Takefumi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyorin University
  •  Role for ER stress responsive ER-Golgi SNARE in processing of Alzheimer`s disease-related protein and autophagy

    • Principal Investigator
      Suga Kei
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyorin University
  •  Functional difference between syntaxin1 isoforms in synaptic transmission

    • Principal Investigator
      AKAGAWA kimio
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Kyorin University
  •  Analysis of syntaxin 1 gene knockout mice as an animal model for autistic disorder

    • Principal Investigator
      AKAGAWA Kimio
    • Project Period (FY)
      2007 – 2009
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyorin University
  •  Role of Syntaxin5 isoforms in neuronal cells under ER stress

    • Principal Investigator
      SUGA Kei
    • Project Period (FY)
      2007 – 2010
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyorin University

All 2016 2015 2013 2010 2009 2008 2007 Other

All Journal Article Presentation

  • [Journal Article] Time lapse imaging analysis of the effect of ER stress modulators on apoptotic cell assessed by caspase3/7 activation in NG108-15 cells2016

    • Author(s)
      Ayako Saito, Kei Suga, Risa Ono-Nakagawa, Masumi Sanada, and Kimio Akagawa
    • Journal Title

      Data in Brief

      Volume: 6 Pages: 20-27

    • DOI

      10.1016/j.dib.2015.11.030

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25430072
  • [Journal Article] ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid beta peptide secretion.2015

    • Author(s)
      K.Suga, A.Saitoh, and K.Akagawa
    • Journal Title

      Experimental cell research

      Volume: 332 Pages: 11-23

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-24300142
  • [Journal Article] Data for the effects of ER and Golgi stresses on the ER-Golgi SNARE Syntaxin5 expression and on the βAPP processing in cultured hippocampal neurons2015

    • Author(s)
      Kei Suga, Ayako Saito, Tatsuya Mishima, and Kimio Akagawa
    • Journal Title

      Data in Brief

      Volume: 5 Pages: 114-123

    • DOI

      10.1016/j.dib.2015.08.023

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25430072
  • [Journal Article] ER and Golgi stresses increase ER-Golgi SNARE Syntaxin5: Implications for organelle stress and βAPP processing2015

    • Author(s)
      Kei Suga, Ayako Saito, Tatsuya Mishima, and Kimio Akagawa
    • Journal Title

      Neurosci. Lett.

      Volume: 604 Pages: 30-35

    • DOI

      10.1016/j.neulet.2015.07.017

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25430072
  • [Journal Article] Data supporting ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion2015

    • Author(s)
      Kei Suga, Ayako Saito, and Kimio Akagawa
    • Journal Title

      Data in Brief

      Volume: 5 Pages: 782-788

    • DOI

      10.1016/j.dib.2015.10.025

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-25430072
  • [Journal Article] ER stress response in NG108-15 cells involves upregulation of syntaxin 5 expression and reduced amyloid β peptide secretion2015

    • Author(s)
      Kei Suga, Ayako Saito, and Kimio Akagawa
    • Journal Title

      Exp.Cell Res.

      Volume: 332 Issue: 1 Pages: 11-23

    • DOI

      10.1016/j.yexcr.2015.01.001

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-25430072
  • [Journal Article] Up-regulation of Syntaxin5 protein expression under ER stress2010

    • Author(s)
      K.Suga, A.Saito, T.Mishima, K.Akagawa
    • Journal Title

      Bull.Jpn.Soc.Neurochem.

      Volume: 49(No.2,3) Pages: 631-631

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Journal Article] The syntaxin 5 isoforms Syx5 and Syx5L have distinct effects on the processing of s-amyloid precursor protein.2009

    • Author(s)
      K. Suga, A. Saito, T. Tomiyama, H. Mori, K. Akagawa
    • Journal Title

      J. Biochem Vol.146

      Pages: 905-915

    • Data Source
      KAKENHI-PROJECT-19300133
  • [Journal Article] The Syntaxin5 isoforms Syx5 and Syx5L have distinct effects on the processing of・APP2009

    • Author(s)
      K. Suga, A. Saito, T. Tomiyama, H. Mori, K. Akagawa
    • Journal Title

      J.Biochem Vol.146, No.6

      Pages: 905-915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Journal Article] The Syntaxin5 isoforms Syx5 and Syx5L have distinct effects on the processing of βAPP2009

    • Author(s)
      K.Suga, A.Saito, T.Tomiyama, H.Mori, K.Akagawa
    • Journal Title

      J.Biochem. 146, No.6

      Pages: 905-915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Journal Article] The Syntaxin5 isoforms Syx5 and Syx5L have distinct effects on the processing of βAPP2009

    • Author(s)
      K.Suga, A.Saito, T.Tomiyama, H.Mori, K.Akagawa
    • Journal Title

      J.Biochem. Vol.146, No.6

      Pages: 905-915

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Journal Article] Role of Syntaxin5 isoforms on the processing and trafficking of βAPP in the ER through the Golgi compartments2009

    • Author(s)
      K.Suga, A.Saito, T.Tomiyama, H.Mori, K.Akagawa
    • Journal Title

      Bull.Jpn.Soc.Neurochem. 48(No.2,3)

      Pages: 193-193

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Journal Article] Distinct effect of Syntaxin5 isoforms on the processing of βAPP2008

    • Author(s)
      K. Suga, A. Saito, T. Tomiyama, H. Mori, K. Akagawa
    • Journal Title

      Bull. Jpn. Soc. Neurochem. 47

      Pages: 253-253

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Journal Article] Effects of Syntaxin5 isoforms on the accumulation of intracellular βAPP and the secretion of Aβ peptides2007

    • Author(s)
      Kei Suga, Ayako Saito, Takami Tomiyama, Hiroshi Mori and Kimio Akagawa
    • Journal Title

      Bull. Jpn. Soc. Neurochem 46

      Pages: 484-484

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Presentation] Upregulation of ER-Golgi SNARE Syntaxin5 by ER stress and its relationship with βAPP processing2015

    • Author(s)
      Kei Suga, Ayako Saito, Tatsuya Mishima, and Kimio Akagawa
    • Organizer
      第58回日本神経化学会大会
    • Place of Presentation
      大宮
    • Year and Date
      2015-09-10
    • Data Source
      KAKENHI-PROJECT-25430072
  • [Presentation] ER stress suppress Abeta secretion and induces the expression of ER-Golgi SNARE including Syntaxin5 proteins in neuronal cells2013

    • Author(s)
      Suga K, Saito A, Mishima T, Akagawa K
    • Organizer
      第56回日本神経化学会大会
    • Place of Presentation
      Kyoto
    • Data Source
      KAKENHI-PROJECT-25430072
  • [Presentation] 神経細胞における小胞体ストレスはAb分泌の抑制とsyntaxin5を含むER-Golgi SNAREの発現量の上昇を引き起こす2013

    • Author(s)
      須賀圭、斎藤綾子、赤川公朗
    • Organizer
      日本神経化学会
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-24300142
  • [Presentation] Up-regulation of Syntaxin5 protein expression under ER stress2010

    • Author(s)
      須賀圭,齋藤綾子、三嶋竜弥、赤川公朗
    • Organizer
      第53回日本神経化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Presentation] Syntaxin5の発現量は小胞体ストレスにより上昇する2010

    • Author(s)
      須賀圭, 齋藤綾子, 三嶋竜弥, 赤川公朗
    • Organizer
      第53回日本神経化学会大会
    • Place of Presentation
      神戸
    • Year and Date
      2010-09-03
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Presentation] 小胞体ストレスにおけるSNARE蛋白質の役割2009

    • Author(s)
      須賀圭, 齋藤綾子, 三嶋竜弥, 赤川公朗
    • Organizer
      第38回杏林医学会
    • Place of Presentation
      東京
    • Year and Date
      2009-11-21
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Presentation] 小胞体とゴルジ体での・APPのプロセシングと細胞内輸送におけるSyntaxin5アイソフォムの役割2009

    • Author(s)
      須賀圭, 齋藤綾子, 富山貴美, 森啓, 赤川公朗
    • Organizer
      第52回日本神経化学会大会
    • Place of Presentation
      伊香保
    • Year and Date
      2009-06-22
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Presentation] 小胞体とゴルジ体での・APPのプロセシングと細胞内輸送におけるSyntaxin5アイソフォームの役割2009

    • Author(s)
      須賀圭,齋藤綾子,富山貴美,森啓,赤川公朗
    • Organizer
      第52回日本神経化学会大会
    • Place of Presentation
      伊香保
    • Year and Date
      2009-06-22
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Presentation] 小胞体とゴルジ体でのβAPPのプロセシングと細胞内輸送におけるSyntaxin5アイソフォームの役割2009

    • Author(s)
      須賀圭, 齋藤綾子, 富山貴美, 森啓, 赤川公朗
    • Organizer
      第52回日本神経化学会大会
    • Place of Presentation
      伊香保
    • Year and Date
      2009-06-22
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Presentation] Distinct effect of Syntaxin5 isofonus on the processing of βAPP2008

    • Author(s)
      須賀圭, 齋藤綾子, 富山貴美, 森啓, 赤川公朗
    • Organizer
      第51回日本神経化学会大会
    • Place of Presentation
      富山
    • Year and Date
      2008-09-13
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Presentation] Effects of Syntaxin5 isoforms on the accumulation of intracellular βAPP and the secretion of Aβ peptides2007

    • Author(s)
      須賀 圭, 齋藤 綾子, 富山 貴美, 森 啓, 赤川 公朗
    • Organizer
      第50回日本神経化学会大会
    • Place of Presentation
      横浜
    • Year and Date
      2007-09-10
    • Data Source
      KAKENHI-PROJECT-19500327
  • [Presentation] Upregulation of ER-Goligi SNARE syntaxin5 by ER stress and its relation with beta APP processing

    • Author(s)
      K.Suga, A.Saito, T.Mishima & K.Akagawa
    • Organizer
      日本神経化学会大会
    • Place of Presentation
      奈良
    • Year and Date
      2014-09-29 – 2014-10-01
    • Data Source
      KAKENHI-PROJECT-24300142
  • [Presentation] Upregulation of ER-Golgi SNARE Syntaxin5 by ER stress and its relationship with βAPP processing

    • Author(s)
      Kei Suga, Ayako Saito, and Kimio Akagawa
    • Organizer
      第57回日本神経化学会大会
    • Place of Presentation
      奈良
    • Year and Date
      2014-09-29 – 2014-10-01
    • Data Source
      KAKENHI-PROJECT-25430072
  • 1.  MISHIMA Tatsuya (40317095)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 9 results
  • 2.  SUGA Kei (30306675)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 27 results
  • 3.  KOFUJI Takefumi (40365200)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 4.  AKAGAWA Kimio (80129303)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 5.  FUJIWARA Tomonori (90255399)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  SANADA Masumi (70424108)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  NAKAYAMA Takahiro (90342823)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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