TANAKA Kazuhiro 田中一裕

Researcher Number	80454586
Affiliation (based on the past Project Information) *help	2007 – 2011: Otani Womens University, 薬学部, 助教
Review Section/Research Field	Principal Investigator Medical pharmacy Except Principal Investigator Biological pharmacy
Keywords	Principal Investigator 脳浮腫 / アストロサイト / アクアポリン / エンドセリン Except Principal Investigator アクアポリン / 脳浮腫 / エンドセリン / アストログリア / 薬理学

Basic research for novel neurotrophic drugs targeting glial endothelin receptors
- Principal Investigator
  
  KOYAMA Yutaka
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Osaka Ohtani University
新規脳浮腫治療の創薬標的分子としてのアストロサイトのエンドセリン受容体Principal Investigator
- Principal Investigator
  
  田中一裕
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Osaka Ohtani University
Evaluation of astrocytic endothelin receptors as therapeutic targets for brain edemaPrincipal Investigator
- Principal Investigator
  
  TANAKA Kazuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Medical pharmacy
- Research Institution
  Otani Womens University

All 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] I. c. v administration of an endothelin ETB receptor agonist stimulates vascular endothelial growth factor-A production and activates vascular endothelial growth factor receptors in rat brain2012
- Author(s)
  Y. Koyama、R. Nagae、S. Tokuyama、K. Tanaka
- Journal Title
  
  Neuroscience
  
  Volume: 192 Pages: 689-698
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590108
[Journal Article] Endothelins decrease the expressions of aquaporins and plasma membrane water permeability in cultured rat astrocytes.2011
- Author(s)
  Tanaka K., Koyama Y.
- Journal Title
  
  J Neurosci Res.
  
  Volume: 89 Pages: 320-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590108
[Journal Article] Endothelins decrease the expressions of aquaporins and plasma membrane water permeability in cultured rat astrocytes2011
- Author(s)
  K. Tanaka, Y. Koyama
- Journal Title
  
  J Neurosci Res
  
  Volume: 89 Pages: 320-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590108
[Journal Article] Intracerebroventricular Administration of an Endothelin ETB Receptor Agonist Increases Expression of Matrix Metalloproteinase-2 and -9 in Rat Brain2010
- Author(s)
  小山豊、田中一裕
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 114の4 Pages: 433-443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790169
[Journal Article] Endothelins Decrease the Expressions of Aquaporins and Plasma Membrane Water Permeability in Cultured Rat Astrocytes2010
- Author(s)
  田中一裕、小山豊
- Journal Title
  
  Journal of Neuroscience Research
  
  Volume: 89の3 Pages: 320-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790169
[Journal Article] Intracerebro-ventricular administration of an endothelin ETB-receptor agonist increases expression of matrix metalloproteinase-2 and-9 in rat brain2010
- Author(s)
  Y. Koyama, T. Tanaka
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 114 Pages: 433-443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590108
[Journal Article] Intracerebroventricular administration of an endothelin ETB-receptor agonist increases expression of matrix Metalloproteinase-2 and -9 in Rat Brain.2010
- Author(s)
  Y.Koyama, T.Tanaka
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 114 Pages: 433-443
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590108
[Journal Article] Decreases in rat brain aquaporin-4 expression following intracerebrovent ricular administration of an endothelin ETB receptor agonist2009
- Author(s)
  Y.Koyama, T.Tanaka
- Journal Title
  
  Neuroscience Letters 469(3)
  
  Pages: 343-347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590108
[Journal Article] Decreases in rat brain aquaporin-4 expression following intracerebroventricular administration of an endothelin ETB receptor agonist2009
- Author(s)
  Y. Koyama, T. Tanaka
- Journal Title
  
  Neuroscience Letters
  
  Volume: 469(3) Pages: 343-347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21590108
[Journal Article] Decreases in rat brain aquaporin-4 expression following intracerebrovent ricular administration of an endothelin ETB receptor agonist2009
- Author(s)
  小山豊、田中一裕
- Journal Title
  
  Neuroscience Letters 469(3)
  
  Pages: 343-347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790169
[Journal Article] Endothelins stimulate the production of stromelysin-1in cultured rat as trocytes2008
- Author(s)
  小山豊、田中一裕
- Journal Title
  
  BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (on line)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890245
[Journal Article] Endothelins stimulate the production of stromelysin-1 in cultured rat astrocytes.2008
- Author(s)
  Yutaka Koyama, Kazuhiro Tanaka
- Journal Title
  
  Biochem Biophys Res Commun 371
  
  Pages: 659-663
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890245
[Presentation] エンドセリンによるラット大脳でのVEGF-A産生促進とVEGF受容体の活性化2011
- Author(s)
  小山豊、永江隆二、徳山尚吾、田中一裕
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  加賀市
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-21590108
[Presentation] エンドセリンによるラット大脳および培養アストロサイトでのアクアポリンの発現変化2010
- Author(s)
  小山豊、田中一裕
- Organizer
  生体機能と創薬シンポジウム2010京都
- Place of Presentation
  京都市
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-21590108
[Presentation] 培養アストロサイトおよびラット大脳皮質におけるVEGF発現に対するエンドセリンの作用2010
- Author(s)
  田中一裕、小山豊
- Organizer
  日本薬理学会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21590108
[Presentation] 培養アストロサイトおよびラット大脳皮質におけるVEGF発現に対するエンドセリンの作用2010
- Author(s)
  田中一裕
- Organizer
  日本薬理学会
- Place of Presentation
  大阪
- Year and Date
  2010-03-17
- Data Source
  KAKENHI-PROJECT-21790169
[Presentation] bEnd3細胞におけるタイトジャンクション関連蛋白発現に対するエンドセリンの作用 (Effects of endothelin-1 on the expression of tight junction proteins in brain microvessel endothelial cells)2009
- Author(s)
  田中一裕, 小山豊
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-19890245
[Presentation] 培養アストロサイトにおけるアクアポリン4発現と水透過性に対するエンドセリンの作用2009
- Author(s)
  田中一裕
- Organizer
  日本神経科学会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-21790169
[Presentation] 培養アストロサイトにおけるアクアポリン4発現と水透過性に対するエンドセリンの作用2009
- Author(s)
  田中一裕、小山豊
- Organizer
  日本神経科学会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-19
- Data Source
  KAKENHI-PROJECT-21590108
[Presentation] bEnd3細胞におけるタイトジャンクション関連蛋白発現に対するエンドセリンの作用2009
- Author(s)
  田中一裕
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2009-03-18
- Data Source
  KAKENHI-PROJECT-19890245
[Presentation] ラット大脳皮質および培養アストロサイトにおけるアクアポリン4発現に対するエンドセリンの作用 (Effects of endothelin on aquaporin-4 expression in the rat cerebral cortex and in cultured rat astrocyte)2009
- Author(s)
  田中一裕, 小山豊
- Organizer
  第129回日本薬学会年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19890245
[Presentation] ラット大脳皮質および培養アストロサイトにおけるアクアポリン4発現に対するエンドセリンの作用2009
- Author(s)
  田中一裕
- Organizer
  日本薬学会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19890245
[Presentation] 培養アストロサイトおよびラット大脳におけるアクアポリン発現に対するエンドセリンの作用2008
- Author(s)
  田中一裕
- Organizer
  日本薬理学会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19890245
[Presentation] 培養アストロサイトおよびラット大脳におけるアクアポリン発現に対するエンドセリンの作用(Endothelin decreases aquaporin-4 mRNA expression in cultured rat astrocyte and in the rat cerebral cortex)2008
- Author(s)
  田中一裕, 小山豊
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19890245
[Presentation] 培養アストロサイトおよびラット大脳におけるアクアポリン4発現に対するエンドセリンの作用(Endothelin decreases aquaporin-4 expression in cultured rat astrocyte and in the rat cerebral cortex)2008
- Author(s)
  田中一裕, 小山豊
- Organizer
  第51回日本神経化学会年会
- Place of Presentation
  富山
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-19890245
[Presentation] 培養アストロサイトおよびラット大脳におけるアクアポリン4発現に対するェンドセリンの作用2008
- Author(s)
  田中一裕
- Organizer
  日本神経化学会
- Place of Presentation
  富山
- Year and Date
  2008-09-11
- Data Source
  KAKENHI-PROJECT-19890245

1. KOYAMA Yutaka (00215435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results

TANAKA Kazuhiro 田中 一裕

Research Projects

Research Products

Co-Researchers

Basic research for novel neurotrophic drugs targeting glial endothelin receptors

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規脳浮腫治療の創薬標的分子としてのアストロサイトのエンドセリン受容体Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Evaluation of astrocytic endothelin receptors as therapeutic targets for brain edemaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] I. c. v administration of an endothelin ETB receptor agonist stimulates vascular endothelial growth factor-A production and activates vascular endothelial growth factor receptors in rat brain2012

Author(s)

Journal Title

Data Source

[Journal Article] Endothelins decrease the expressions of aquaporins and plasma membrane water permeability in cultured rat astrocytes.2011

Author(s)

Journal Title

Data Source

[Journal Article] Endothelins decrease the expressions of aquaporins and plasma membrane water permeability in cultured rat astrocytes2011

Author(s)

Journal Title

Data Source

[Journal Article] Intracerebroventricular Administration of an Endothelin ETB Receptor Agonist Increases Expression of Matrix Metalloproteinase-2 and -9 in Rat Brain2010

Author(s)

Journal Title

Data Source

[Journal Article] Endothelins Decrease the Expressions of Aquaporins and Plasma Membrane Water Permeability in Cultured Rat Astrocytes2010

Author(s)

Journal Title

Data Source

[Journal Article] Intracerebro-ventricular administration of an endothelin ETB-receptor agonist increases expression of matrix metalloproteinase-2 and-9 in rat brain2010

Author(s)

Journal Title

Data Source

[Journal Article] Intracerebroventricular administration of an endothelin ETB-receptor agonist increases expression of matrix Metalloproteinase-2 and -9 in Rat Brain.2010

Author(s)

Journal Title

Data Source

[Journal Article] Decreases in rat brain aquaporin-4 expression following intracerebrovent ricular administration of an endothelin ETB receptor agonist2009

Author(s)

Journal Title

Data Source

[Journal Article] Decreases in rat brain aquaporin-4 expression following intracerebroventricular administration of an endothelin ETB receptor agonist2009

Author(s)

Journal Title

Data Source

[Journal Article] Decreases in rat brain aquaporin-4 expression following intracerebrovent ricular administration of an endothelin ETB receptor agonist2009

Author(s)

Journal Title

Data Source

[Journal Article] Endothelins stimulate the production of stromelysin-1in cultured rat as trocytes2008

Author(s)

Journal Title

Data Source

[Journal Article] Endothelins stimulate the production of stromelysin-1 in cultured rat astrocytes.2008

Author(s)

Journal Title

Data Source

[Presentation] エンドセリンによるラット大脳でのVEGF-A産生促進とVEGF受容体の活性化2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] エンドセリンによるラット大脳および培養アストロサイトでのアクアポリンの発現変化2010

Author(s)

Organizer

Place of Presentation

TANAKA Kazuhiro 田中一裕