NAGASHIMA Reiko 長嶋玲子

Researcher Number	80454651
Affiliation (based on the past Project Information) *help	2011: 摂南大学, 薬学部・薬理学研究室, 助教 2010 – 2011: 摂南大学, 薬学部, 助教 2008: Setsunan University, 薬学部, 教授 2007 – 2008: Setsunan University, 薬学部, 助教
Review Section/Research Field	Principal Investigator Medical pharmacy
Keywords	Principal Investigator ステロイド性薬 / Na^+K^+-ATPase / 抗酸化剤 / コネキシン蛋白 / 感音難聴 / Na^+,K^+-ATPase / コネキシン蛋白質 / 酸化ストレス / 音響外傷性難聴 / 臨床薬学 … More / 蝸牛外側壁線維細胞 / p-AMPK / AMP-activated protein kinase(AMPK) / ATP産生 / ミトコンドリア障害 / 突発性難聴 / 5'-AMP-activated protein kinase / JNKシグナル / 5'-AMP-activated-protein-kinase / 音響誘発性難聴 / 蝸牛外側壁 Less

Research Projects
(2 results)
Research Products
(56 results)

Novel drug therapy plan for sensor i neural deafness with steroidal drugs and radical scavengerPrincipal Investigator
- Principal Investigator
  
  NAGASHIMA Reiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Medical pharmacy
- Research Institution
  Setsunan University
Evaluation of mechanisms underlying steroid therapy for deafnessPrincipal Investigator
- Principal Investigator
  
  NAGASHIMA Reiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Medical pharmacy
- Research Institution
  Setsunan University

All 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

[Journal Article] Acoustic over stimulation activates 5'-AMPactivated protein kinase through a temporary decrease in ATP level in the cochlear spiral ligament prior to permanent hearing loss in mice2011
- Author(s)
  Nagashima R, Yamaguchi T, Kuramoto N, Ogita K
- Journal Title
  
  Neurochem. Int
  
  Volume: 59 Pages: 812-820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790174
[Journal Article] Acoustic overstimulation activates 5'-AMP-activated protein kinase through a temporary decrease in ATP level in the cochlear spiral ligament prior to permanent hearing loss in mice2011
- Author(s)
  Nagashima R, Yamaguchi T, Kuramoto N, Ogita K
- Journal Title
  
  Neurochem.Int.
  
  Volume: Vol.59 Pages: 812-820
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790174
[Journal Article] Mechanism underlying the protective effect of tempol and Nω-nitro-L-arginine methyl ester on acoustic injury : possible involvement of c-Jun N-terminal kinase pathway and connexin26 in the cochlear spiral ligament.2010
- Author(s)
  Nagashima R, Yamaguchi T, Tanaka H, Ogita K
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: VOL.114 Pages: 50-62
- NAID
  10029889750
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790174
[Journal Article] Mechanism underlying the protective effect of tempol and N w nitroLarginine methyl ester on acoustic injury : possible involvement of c-Jun Nterminal kinase pathway and connexin26 in the cochlear spiral ligament2010
- Author(s)
  Nagashima R, Yamaguchi T, Tanaka H, Ogita K
- Journal Title
  
  J Pharmacol Sci
  
  Volume: 114 Pages: 50-62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790174
[Journal Article] Altered expression of heat shock protein 110 family members in mouse hippocampal neurons following trimethyltin treatment in vivo and in vitro2008
- Author(s)
  Masanori Yoneyama, Naoko Iwamoto, Reiko Nagashima, Chie Sugiyama, Koichi Kawada, Nobuyuki Kuramoto, Makoto Shuto, Kiyokazu Ogita
- Journal Title
  
  Neuropharmacolog 55
  
  Pages: 693-703
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890248
[Journal Article] Altered expression of DJ-1 in the hippocarapal cells following in vivo and in vitro neurona l damage induced by trimethyltin2008
- Author(s)
  Reiko Nagashima, Chie Sugiyama, Yuka Gotoh, Masanori Yoneyama, Nobuyuki Kuramoto, Takahiro Taira, Hiroyoshi Ariga, Kiyokazu Ogita
- Journal Title
  
  Neurosci. Lett. 440
  
  Pages: 232-236
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890248
[Journal Article] Enhanced expression of RNase L as a novel intracellular signal generated by NMDA receptors in mouse cortical neurons2008
- Author(s)
  Chie Sugiyama, Nobuyuki Kuramoto, Reiko Nagashima, Masanori Yoneyama, Kiyokazu Ogita
- Journal Title
  
  eurochem. Int. 53
  
  Pages: 71-78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890248
[Journal Article] In vivo depletion of endogenous glutathione facilitates trimcthyltin-mduced neuronal damage in the dentate gyrus of mice by enhancing oxidative stress2007
- Author(s)
  Masanori Yoneyama, Norito Nishiyama, Makoto Shuto, Chie Sugiyama, Koichi Kawada, Keiichi Seko, Reiko Nagashima, Kiyokazu Ogita
- Journal Title
  
  Neurochemi Int. 52
  
  Pages: 761-769
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890248
[Journal Article] Acoustic overstimulation facilitates the expression of glutamate-cysteine ligase catalytic subunit probably through enhanced DNA binding of activator protein-1 and/or NF-κB in the murine cochlea2007
- Author(s)
  Nagashima R, Chie Sugiyama, Masanori Yoneyama, Nobuyuki Kuramoto, Koichi Kawada, Kiyokazu Ogita
- Journal Title
  
  Neurochemistry Int. 51
  
  Pages: 209-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890248
[Journal Article] In vivo acuye treatment with trimethyltin chloride causes neuronal degeneration in the murine olfactory bulb and anterior olfactory nucleus by different cascades in each region2007
- Author(s)
  Koichi Kawada, Masanori Yoneyama, Reiko Nagashima, Kiyokazu Ogita
- Journal Title
  
  J Neuroscience Res. 86
  
  Pages: 1635-1646
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890248
[Journal Article] Acoustic overstimulation facilitates the expression of glutamate-cysteine ligase catalytic subunit probably through enhanced DNA binding of activator protein-1 and/or NF-κB in the murine cochlea2007
- Author(s)
  Reiko Nagashima
- Journal Title
  
  Neurochemistry International 51
  
  Pages: 209-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] 酸化ストレスによる蝸牛らせん靭帯のギャップ結合機能の破綻におけるカルパインの関与2012
- Author(s)
  長嶋玲子
- Organizer
  第85回日本薬理学会年会
- Place of Presentation
  京都
- Year and Date
  2012-03-15
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 音響外傷性難聴発症メカニズムとしての蝸牛外側壁らせん靭帯線維細胞における酸化ストレス誘発性ギャップ結合機能の破綻2011
- Author(s)
  山口太郎、長嶋玲子、荻田喜代一
- Organizer
  第199回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 強大音響外傷に伴う蝸牛外側壁におけるNa^+, K^+-ATPaseの活性低下2011
- Author(s)
  山口太郎、長嶋玲子、荻田喜代一
- Organizer
  日本薬学会131回年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 音響曝露による外側壁におけるMAPK経路の活性化2011
- Author(s)
  中島理依、松下綾子、長嶋玲子、荻田喜代一
- Organizer
  日本薬学会131回年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 音響外傷性難聴発症メカニズムとしての蝸牛外側壁らせん靭帯線維細胞における酸化ストレス誘発性Na^+, K^+-ATPase活性の低下2011
- Author(s)
  長嶋玲子、山口太郎、荻田喜代一
- Organizer
  第119回日本薬理学会近畿部会
- Place of Presentation
  名古屋
- Year and Date
  2011-07-08
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 強大音響曝露誘発性聴覚障害時の蝸牛内NOシグナルの活性化2011
- Author(s)
  長嶋玲子、山口太郎、荻田喜代一
- Organizer
  日本薬学会131回年会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] Reduced Na^+, K^+-ATPase activity in the cochlear spiral ligaments by acoustic over stimulation-inducedoxidative stress2011
- Author(s)
  Reiko Nagashima, Taro Yamaguchi, Kiyokazu Ogita
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  金沢
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] Burst of NO/cGMP/protein kinase G signals in hearing loss induced by acoustic injury2011
- Author(s)
  Taro Yamaguchi, Reiko Nagashima, Kiyokazu Ogita
- Organizer
  第84回日本薬理学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 強大音響誘発性酸化ストレスによる蝸牛らせん靭帯のNa^+, K^+-ATPase活性低下2011
- Author(s)
  長嶋玲子
- Organizer
  第54回日本神経化学会大会
- Place of Presentation
  金沢
- Year and Date
  2011-09-26
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] Prolonged decrease in the expression of connexins in the cochlear spiral ligament fibrocytes following intense noise exposure2011
- Author(s)
  Reiko Nagashima, Taro Yamaguchi, Kiyokazu Ogita
- Organizer
  第23回国際神経化学会大会
- Place of Presentation
  ギリシャ
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] Intensenoise exposure activate JNK signal via generation of nitric oxide in cochlear spiral ligament fibrocytes2010
- Author(s)
  Hajime Tanaka, Reiko Nagashima, Taro Yamaguchi, Kiyokazu Ogita
- Organizer
  Neuro
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] Involvement of cGMP/protein kinase G-independent signals for nitric oxide in hearing loss induced by acoustic injury2010
- Author(s)
  Reiko Nagashima, Taro Yamaguchi, Kiyokazu Ogita
- Organizer
  Neuro
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] Decreased expression of gap junction protein connexin26 through enhancement of oxidative stress in noiseinduced hearing loss2010
- Author(s)
  Taro Yamaguchi, Reiko Nagashima, Kiyokazu Ogita
- Organizer
  Neuro
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] Decreased expression of connexin 26 in the cochlear spiral ligament fibrocyte following intense noise exposure2010
- Author(s)
  Reiko Nagashima, Taro Yamaguchi, Hajime Tanaka, Ayako Matsushita, Kiyokazu Ogita
- Organizer
  6th World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 蝸牛外側壁らせん靭帯線維細胞におけるギャップ結合構成蛋白質の強大音響曝露による発現制御2010
- Author(s)
  長嶋玲子
- Organizer
  日本薬理学会近畿部会
- Place of Presentation
  大阪
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] Decreased expression of connexin 26 in the cochlear spiral ligament fibrocyte following intense noise exposure.2010
- Author(s)
  長嶋玲子
- Organizer
  16th World Congress on Basic and Clinical Pharmacology
- Place of Presentation
  デンマーク(コペンハーゲン)
- Year and Date
  2010-07-22
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 強大音響曝露による永久的聴力障害の原因となる蝸牛外側壁の機能低下2010
- Author(s)
  山口太郎, 長嶋玲子, 荻田喜代一
- Organizer
  薬学会近畿支部会
- Place of Presentation
  大阪
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 強大音響誘発性内耳障害における蝸牛外側壁らせん靭帯線維細胞でのNO/JNKsignalの活性化2010
- Author(s)
  田中始, 長嶋玲子, 山口太郎, 荻田喜代一
- Organizer
  薬学会近畿支部会
- Place of Presentation
  大阪
- Year and Date
  2010-10-30
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 音響外傷に伴う内耳機能蛋白質の発現制御と永久的聴力障害2010
- Author(s)
  山口太郎、長嶋玲子、荻田喜代一
- Organizer
  医療薬理シンポジウム
- Place of Presentation
  京都
- Year and Date
  2010-09-11
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] Involvement of cGMP/protein kinase G-independent signals for nitric oxide in hearing loss induced by acoustic injury2010
- Author(s)
  長嶋玲子
- Organizer
  Neuro2010
- Place of Presentation
  神戸
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 蝸牛外側壁らせん靭帯線維細胞におけるギャップ結合構成蛋白質の強大音響曝露による発現制御2010
- Author(s)
  長嶋玲子、山口太郎、荻田喜代一
- Organizer
  日本薬理学会近畿支部会
- Place of Presentation
  大阪
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 強大音響曝露は酸化ストレスを介した蝸牛外側壁線維細胞の機能蛋白質の発現を制御する2010
- Author(s)
  長嶋玲子、山口太郎、荻田喜代一
- Organizer
  創薬シンポジウム
- Place of Presentation
  京都
- Year and Date
  2010-09-09
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 強大音響曝露による蝸牛外側壁らせん靭帯線維細胞におけるNO依存性mitogen預ctivated protein kinase経路の活性化2010
- Author(s)
  田中始、長嶋玲子、松下綾子、山口太郎、荻田喜代一
- Organizer
  日本薬理学会近畿支部会
- Place of Presentation
  大阪
- Year and Date
  2010-11-19
- Data Source
  KAKENHI-PROJECT-22790174
[Presentation] 強大音響誘発性聴覚障害に.対するTempolとL-Nitroarginine methyl esterの効果2009
- Author(s)
  長嶋玲子, 渡邊夏子, 荻田喜代一
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] マウス胎児大脳皮質由来神経系前駆細胞の増殖における5'-AMP-activated protein kinaseの役割2009
- Author(s)
  佐野尚平, 長嶋玲子, 米山雅紀, 倉本展行, 荻田喜代
- Organizer
  第129回日本薬学会年会
- Place of Presentation
  京都
- Year and Date
  2009-03-28
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] 強大音響誘発性聴覚障害に対するTempo]とL-Nitroaroarginine methvl esterの効果2009
- Author(s)
  長嶋玲子
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] 海馬歯状回神経障害後の神経再生時における4-hydroxynonenal付加蛋白質の発現増強2009
- Author(s)
  Shohei Sano, Keiko shimizu, Reiko Nagashima, Kiyokazu Ogita
- Organizer
  第82回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-03-17
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] 強大音響曝露による蝸牛外側壁線維細胞のAMP-activated protein kinaseシグナルの活性化2009
- Author(s)
  長嶋玲子, 鈴木有香, 倉本展行, 荻田喜代一
- Organizer
  第129回日本薬学会年会
- Place of Presentation
  京都
- Year and Date
  2009-03-27
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] Changes in glutathione-related enzymes in the hippocampus after in vivo treatment with trimethyltin2008
- Author(s)
  Reiko Nagashima
- Organizer
  第81回日本薬理学
- Place of Presentation
  横浜
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] Enhanced expression of glutathione S-transferase in the hippocampus of mice after trimethyltin treatment2008
- Author(s)
  Shohei Sano, Reiko Nagashima, Kiyokazu Ogita
- Organizer
  第51回日本神経化学会大会
- Place of Presentation
  富山
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] In vivo intense noise exposure activates AMP-activated protein kinase in the cochlcar spiral ligament fibrocytos of mice2008
- Author(s)
  長嶋玲子
- Organizer
  Neurosience 2008
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] トリメチルスズによるマウス海馬内glutathione S-transferase遺伝子の発現増強2008
- Author(s)
  佐野尚平, 長嶋玲子、, 荻田喜代一
- Organizer
  第58回日本薬学会近幾支部会総会
- Place of Presentation
  神戸
- Year and Date
  2008-10-25
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] Changes in glutathione-related enzymes by trimethyltin administration in mouse hippocampus2008
- Author(s)
  Reiko Nagashima, Shohei Sano, Haeja Han, Kiyokazu Ogita
- Organizer
  ECNP
- Place of Presentation
  スペイン
- Year and Date
  2008-08-31
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] 強音曝露は蝸牛靭帯線維細胞のAMP-activated protein kinaseを活性化する2008
- Author(s)
  長嶋玲子, 倉本展行, 荻田喜代一
- Organizer
  Neurosience2008
- Place of Presentation
  東京
- Year and Date
  2008-07-09
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] 強大音響曝露による蝸牛外側壁線維細胞におけるAMPKの活性化2008
- Author(s)
  長嶋玲子, 倉本展行, 荻田喜代一
- Organizer
  第128回日本薬学会
- Place of Presentation
  横浜
- Year and Date
  2008-03-27
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] Changes in glutathione-related enzymes in the hippocampus after in vivo treatment with trimethyltin2008
- Author(s)
  Reiko Nagashima, Shohei Sano, Kiyokazu Ogita
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  横浜
- Year and Date
  2008-03-19
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] デキサメタゾンによる蝸牛内グルタチオンの増加2007
- Author(s)
  長嶋玲子, 荻田喜代一
- Organizer
  薬物活性シンポジウム
- Place of Presentation
  広島
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] 蝸牛内グルタチオンに対するデキサメタゾンの影響2007
- Author(s)
  長嶋玲子, 荻田喜代一
- Organizer
  第6回ファーマバイオフォーラム 2007
- Place of Presentation
  大阪
- Year and Date
  2007-12-02
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] ラット内耳の蝸牛外側壁線維細胞の生後変化2007
- Author(s)
  長嶋玲子, 務台英樹, 松永達雄, 荻田喜代一
- Organizer
  Neuro2007
- Place of Presentation
  横浜
- Year and Date
  2007-09-11
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] ラット内耳の蝸牛外側壁線維細胞の生後発達2007
- Author(s)
  長嶋玲子, 務台英樹, 松永達雄, 荻田喜代一
- Organizer
  第111回日本薬理学会近畿部会
- Place of Presentation
  金沢
- Year and Date
  2007-06-15
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] Developm6ntal expression of cochlear spiral ligament fibrocytes in rat inner ear2007
- Author(s)
  Reiko Nagashima
- Organizer
  Neuroscience2007
- Place of Presentation
  アメリカ(サンディエゴ)
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] 胎児大脳皮質の培養神経系前駆細胞に対するトリメチルスズ毒性2007
- Author(s)
  長嶋玲子, 世古敬一, 米山雅紀, 荻田喜代一
- Organizer
  神経精神薬理学会第37回年会
- Place of Presentation
  札幌
- Year and Date
  2007-07-12
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] Developmental expression of cochlear spiral ligament fibrocytes in rat inner ear2007
- Author(s)
  Reiko Nagashima, Hideki Mutai, Tatsuo Matsunaga, Kiyokazu Ogita
- Organizer
  Neuroscience2007
- Place of Presentation
  アメリカ
- Year and Date
  2007-11-04
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] 蝸牛内グルタチオンに対するデキサメタゾンの影響2007
- Author(s)
  長嶋玲子
- Organizer
  第6回ファーマバイオラォーラム2007
- Place of Presentation
  大阪
- Year and Date
  2007-12-02
- Data Source
  KAKENHI-PROJECT-19890248
[Presentation] デキサメタゾシによる蝸牛内グルタチオンの増加2007
- Author(s)
  長嶋玲子
- Organizer
  薬物活性シンポジウム
- Place of Presentation
  広島
- Year and Date
  2007-11-29
- Data Source
  KAKENHI-PROJECT-19890248

NAGASHIMA Reiko 長嶋 玲子

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Novel drug therapy plan for sensor i neural deafness with steroidal drugs and radical scavengerPrincipal Investigator

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Evaluation of mechanisms underlying steroid therapy for deafnessPrincipal Investigator

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[Journal Article] Acoustic over stimulation activates 5'-AMPactivated protein kinase through a temporary decrease in ATP level in the cochlear spiral ligament prior to permanent hearing loss in mice2011

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[Journal Article] Acoustic overstimulation activates 5'-AMP-activated protein kinase through a temporary decrease in ATP level in the cochlear spiral ligament prior to permanent hearing loss in mice2011

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[Journal Article] Mechanism underlying the protective effect of tempol and Nω-nitro-L-arginine methyl ester on acoustic injury : possible involvement of c-Jun N-terminal kinase pathway and connexin26 in the cochlear spiral ligament.2010

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[Journal Article] Mechanism underlying the protective effect of tempol and N w nitroLarginine methyl ester on acoustic injury : possible involvement of c-Jun Nterminal kinase pathway and connexin26 in the cochlear spiral ligament2010

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[Journal Article] Altered expression of heat shock protein 110 family members in mouse hippocampal neurons following trimethyltin treatment in vivo and in vitro2008

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[Journal Article] Altered expression of DJ-1 in the hippocarapal cells following in vivo and in vitro neurona l damage induced by trimethyltin2008

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[Journal Article] Enhanced expression of RNase L as a novel intracellular signal generated by NMDA receptors in mouse cortical neurons2008

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[Journal Article] In vivo depletion of endogenous glutathione facilitates trimcthyltin-mduced neuronal damage in the dentate gyrus of mice by enhancing oxidative stress2007

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[Journal Article] Acoustic overstimulation facilitates the expression of glutamate-cysteine ligase catalytic subunit probably through enhanced DNA binding of activator protein-1 and/or NF-κB in the murine cochlea2007

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[Journal Article] In vivo acuye treatment with trimethyltin chloride causes neuronal degeneration in the murine olfactory bulb and anterior olfactory nucleus by different cascades in each region2007

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[Journal Article] Acoustic overstimulation facilitates the expression of glutamate-cysteine ligase catalytic subunit probably through enhanced DNA binding of activator protein-1 and/or NF-κB in the murine cochlea2007

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[Presentation] 酸化ストレスによる蝸牛らせん靭帯のギャップ結合機能の破綻におけるカルパインの関与2012

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[Presentation] 音響外傷性難聴発症メカニズムとしての蝸牛外側壁らせん靭帯線維細胞における酸化ストレス誘発性ギャップ結合機能の破綻2011

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[Presentation] 強大音響外傷に伴う蝸牛外側壁におけるNa^+, K^+-ATPaseの活性低下2011

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[Presentation] 音響曝露による外側壁におけるMAPK経路の活性化2011

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NAGASHIMA Reiko 長嶋玲子