KUSAKAWA Shinnji 草川森士

Researcher Number	80462802
Affiliation *help	2016 – 2018 : 国立医薬品食品衛生研究所, 再生・細胞医療製品部, 主任研究官 2016 – 2018 : 国立研究開発法人国立成育医療研究センター, 細胞医療研究部, 共同研究員 2012 – 2015 : 公益財団法人先端医療振興財団, その他部局等, 研究員 2014 : 公益財団法人先端医療振興財団, 細胞療法研究開発センター, 研究員 2011 : (財)先端医療振興財団, その他部局等, 研究員 2008 – 2009 : National Research Institute for Child Health and Development, 薬剤治療研究部, 共同研究員 2009 : National Research Institute for Child Health and Development, 薬剤治療研究部, 共同研究員
Review Section/Research Field	Principal Investigator Medical engineering assessment / Pediatrics / Applied pharmacology / Basic Section 90140:Medical technology assessment-related
Keywords	Principal Investigator 催奇形性 / ヒトiPS細胞 / 未分化細胞 / 抗うつ済 / 薬物毒性 / 発生毒性 / 発達障害 / 抗精神病薬 / 分化マーカー遺伝子 / 分化誘導 … More

新しい三次元細胞培養技術を利用した再生医療等製品の造腫瘍性関連試験の開発Principal InvestigatorOngoing
- Principal Investigator
  
  草川森士
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90140:Medical technology assessment-related
- Research Institution
  National Institute of Health Sciences
発生毒性を持つ医薬品を利用した未分化多能性幹細胞の選択的除去法の構築Principal InvestigatorOngoing
- Principal Investigator
  
  草川森士
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Medical engineering assessment
- Research Institution
  Foundation for Biomedical Research and Innovation
Technical development for the identification of cardiomyocyte differentiation-promoting factorsPrincipal Investigator
- Principal Investigator
  
  KUSAKAWA Shinji
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Foundation for Biomedical Research and Innovation
Establishment of new toxicity test using mouse ES cellsPrincipal Investigator
- Principal Investigator
  
  KUSAKAWA Shinnji
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied pharmacology
- Research Institution
  National Research Institute for Child Health and Development

All 2015 2012 2011 2009 2008 Other

All Journal Article Presentation Book

[Book] 再生医療規制の動向と製品開発および産業化の注意点（第3章細胞加工製品の安全性に関する海外の規制と日本での規制・非臨床安全性評価）2015
- Author(s)
  草川森士，佐藤陽治
- Total Pages
  180
- Publisher
  情報機構
- Data Source
  KAKENHI-PROJECT-23791209
[Journal Article] Characterization of in vivo tumorigenicity tests using severe immunodeficient NOD/Shi-scid IL2Rγnull mice for detection of tumorigenic cellular impurities in human cell-processed therapeutic products.2015
- Author(s)
  Kusakawa Shinji, Machida Kazuhiko, Yasuda Satoshi, Takada Nozomi, Kuroda Takuya, Sawada Rumi, Okura Hanayuki, Tsutsumi Hideki, Kawamata Shin, Sato Yoji.
- Journal Title
  
  Regenerative Therapy
  
  Volume : 1 Pages : 30-37
- Open Access / Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791209
[Journal Article] Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells2012
- Author(s)
  Kuroda T., Yasuda S., Kusakawa S., Hirata N., Kanda Y., Suzuki K., Takahashi M., Nishikawa S., Kawamata S and Sato Y.
- Journal Title
  
  PLoS One
  
  Volume : 7
- DOI
  10.1371/journal.pone.0037342
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590322, KAKENHI-PROJECT-23790116, KAKENHI-PROJECT-23791209
[Journal Article] The atypical guanine-nucleotide exchange factor, Dock7, negatively regulates Schwann cell differentiation and myelination2011
- Author(s)
  Junji Yamauchi, Yuki Miyamoto, Hajime Hamasaki, Atsushi Sanbe, Shinji Kusakawa, Akane Nakamura, Hideki Tsumura, Masahiro Maeda, Noriko Nemoto, Katsumasa Kawahara, Tomohiro Torii, and Akito Tanoue
- Journal Title
  
  Journal of Neuroscience
  
  Volume : 31 Pages : 12579-12592
- DOI
  10.1523/jneurosci.2738-11.2011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300123, KAKENHI-PROJECT-23650200, KAKENHI-PROJECT-23791209
[Journal Article] Estimation of embryotoxic effect of fluoxetine using embryonic stem cell differentiation system.2008
- Author(s)
  Kusakawa S, Yamauchi J, Miyamoto Y, Sanbe A, Tanoue A
- Journal Title
  
  Life Sciences. 83
  
  Pages : 871-877
- Data Source
  KAKENHI-PROJECT-20790407
[Journal Article] Estimation of embryotoxic effect of fluoxetine using embryonic stem cell differentiation system2008
- Author(s)
  Kusakawa S, Yamauchi J, Miyamoto Y, Sanbe A, Tanoue A
- Journal Title
  
  Life Sciences 83
  
  Pages : 871-877
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790407
[Journal Article] マウス胚性幹細胞を利用したSSRIの発生毒性評価2008
- Author(s)
  草川森士、宮本幸、藤原葉子、三部篤、小出寛、山内淳司、田上昭人
- Journal Title
  
  日本小児臨床薬理学会雑誌第21巻
  
  Pages : 147-150
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790407
[Journal Article] マウス胚性幹細胞を利用したSSRIの発生毒性評価2008
- Author(s)
  草川森士, 宮本幸, 藤原葉子, 三部篤, 小出寛, 山内淳司, 田上昭人
- Journal Title
  
  日本小児臨床薬理学会雑誌 21,1
- Data Source
  KAKENHI-PROJECT-20790407
[Presentation] レポーター蛋白を利用した多能性幹細胞の神経分化の評価2012
- Author(s)
  草川森士, 舩田正彦, 安田智, 黒田拓也, 山内淳司, 佐藤陽治
- Organizer
  第３５回神経科学大会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23791209
[Presentation] 抗うつ剤フルオキセチンはマウスES細胞をグリア系細胞系譜に誘導する2011
- Author(s)
  草川森士, 宮本幸, 中村和昭, 三部篤, 鳥居知宏, 田上昭人, 山内淳司
- Organizer
  第８４回日本生化学大会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23791209
[Presentation] 胚性幹細胞の神経分化過程におけるSSRIの影響2009
- Author(s)
  草川森士、宮本幸、三部篤、山内淳司、田上昭人
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790407
[Presentation] 胚性幹細胞を用いた薬剤の発生毒性評価2009
- Author(s)
  草川森士、田上昭人
- Organizer
  第36回日本小児臨床薬理学会
- Place of Presentation
  香川
- Data Source
  KAKENHI-PROJECT-20790407
[Presentation] Embryonic stem cell test(EST法)を用いた薬剤の発生毒性評価-抗てんかん剤2009
- Author(s)
  草川森士、田上昭人
- Organizer
  抗うつ剤の発生毒性評価-第22回日本動物実験代替法学会総会・学術大会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-20790407
[Presentation] 胚性幹細胞を用いた薬剤の発生毒性評価2009
- Author(s)
  草川森士, 田上昭人
- Organizer
  第36回日本小児臨床薬理学会大西記念賞受賞講演
- Place of Presentation
  香川
- Year and Date
  2009-11-20
- Data Source
  KAKENHI-PROJECT-20790407
[Presentation] Embryonic stem cell test (EST法)を用いた薬剤の発生毒性評価-抗てんかん剤、抗うつ剤の発生毒性評価-2009
- Author(s)
  草川森士, 田上昭人
- Organizer
  第22回日本動物実験代替法学会総会・学術大会シンポジウム(ES, ips細胞を使用した代替法研究)
- Place of Presentation
  大阪
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-20790407
[Presentation] Fstimation of the developmental neurotoxicity of SSRI using an ES cell differentiation system胚性幹細胞の神経分化過程におけるSSRIの影響2009
- Author(s)
  草川森士, 山内淳司, 三部篤, 宮本幸, 田上昭人
- Organizer
  第32回日本神経科学大会
- Place of Presentation
  名古屋
- Year and Date
  2009-09-16
- Data Source
  KAKENHI-PROJECT-20790407
[Presentation] A NEW SOFT AGAR COLONY FORMATION ASSAY BASED ON HIGH-CONTENT IMAGING FOR SENSITIVE DETECTION OF TUMORIGENIC CELLULAR IMPURITIES IN HUMAN CELL-PROCESSED THERAPEUTIC PRODUCTS.
- Author(s)
  Kusakawa Shinji, Yasuda Satoshi, Kuroda Takuya, Kawamata Shin, Sato Yoji
- Organizer
  ISSCR Regional Forum Series 2014 GLOBAL CONTROLS IN STEM CELLS
- Place of Presentation
  Syngapore
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-23791209
[Presentation] 軟寒天コロニー形成試験を応用した再生医療製品に混在する悪性形質転換細胞の高感度検出法
- Author(s)
  草川森士，安田智，黒田拓也，川真田伸，佐藤陽治
- Organizer
  第14回日本再生医療学会総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-03-19 – 2015-03-21
- Data Source
  KAKENHI-PROJECT-23791209

1. KANDA Yasunari

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
2. 安田智

# of Collaborated Projects : 0results

# of Collaborated Products : 1results
3. 山内淳司

# of Collaborated Projects : 0results

# of Collaborated Products : 1results

KUSAKAWA Shinnji 草川 森士

Research Projects

Research Products

Co-Researchers

新しい三次元細胞培養技術を利用した再生医療等製品の造腫瘍性関連試験の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

発生毒性を持つ医薬品を利用した未分化多能性幹細胞の選択的除去法の構築Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Technical development for the identification of cardiomyocyte differentiation-promoting factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of new toxicity test using mouse ES cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 再生医療規制の動向と製品開発および産業化の注意点（第3章 細胞加工製品の安全性に関する海外の規制と日本での規制・非臨床安全性評価）2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Characterization of in vivo tumorigenicity tests using severe immunodeficient NOD/Shi-scid IL2Rγnull mice for detection of tumorigenic cellular impurities in human cell-processed therapeutic products.2015

Author(s)

Journal Title

Data Source

[Journal Article] Highly sensitive in vitro methods for detection of residual undifferentiated cells in retinal pigment epithelial cells derived from human iPS cells2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The atypical guanine-nucleotide exchange factor, Dock7, negatively regulates Schwann cell differentiation and myelination2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Estimation of embryotoxic effect of fluoxetine using embryonic stem cell differentiation system.2008

Author(s)

Journal Title

Data Source

[Journal Article] Estimation of embryotoxic effect of fluoxetine using embryonic stem cell differentiation system2008

Author(s)

Journal Title

Data Source

[Journal Article] マウス胚性幹細胞を利用したSSRIの発生毒性評価2008

Author(s)

Journal Title

Data Source

[Journal Article] マウス胚性幹細胞を利用したSSRIの発生毒性評価2008

Author(s)

Journal Title

Data Source

[Presentation] レポーター蛋白を利用した多能性幹細胞の神経分化の評価2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 抗うつ剤フルオキセチンはマウスES細胞をグリア系細胞系譜に誘導する2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 胚性幹細胞の神経分化過程におけるSSRIの影響2009

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 胚性幹細胞を用いた薬剤の発生毒性評価2009

Author(s)

KUSAKAWA Shinnji 草川森士

[Book] 再生医療規制の動向と製品開発および産業化の注意点（第3章細胞加工製品の安全性に関する海外の規制と日本での規制・非臨床安全性評価）2015