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Matsumoto Misaki  松本 みさき

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MSATSUMOTO Misaki  松本 みさき

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Researcher Number 80533926
Other IDs
Affiliation (Current) 2025: 和歌山県立医科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help 2023: 和歌山県立医科大学, 薬学部, 准教授
2010 – 2023: Kyoto Prefectural University of Medicine, 医学(系)研究科(研究院), 助教
2015: 京都府立医科大学, 大学院医学研究科, 助教
2012: 京都府立医科大学, 医学研究科, 助教
2009: Nagasaki University, 医歯薬学総合研究科, 技能補佐員
2009: 長崎大学, 大学院・医歯薬学総合研究科, 技能補佐員
Review Section/Research Field
Principal Investigator
General pharmacology / Basic Section 48030:Pharmacology-related / 疼痛学
Except Principal Investigator
General pharmacology / Basic Section 48030:Pharmacology-related / Neurochemistry/Neuropharmacology / 疼痛学
Keywords
Principal Investigator
スーパーオキシド / NADPH oxidase / 活性酸素種 / 関節炎 / 慢性炎症 / ミエロイド / ミエロイド細胞 / 顆粒球 / 造血 / 骨髄 … More / 活性酸素 / リポ多糖 / リポポリサッカライド / 自己免疫疾患 / 免疫学 / 薬理学 / 抗体産生 / 喘息 / 免疫 / NASH / 肝臓 / 一酸化窒素 / 肝類洞 / 酸化ストレス / 非アルコール性脂肪性肝炎 / マウス / 抗体 / 大腸 / 痛み / 神経因性疼痛 … More
Except Principal Investigator
活性酸素種 / NADPHオキシダーゼ / 心線維化 / NADPH オキシダーゼ / 拡張機能不全型心不全 / 細胞外マトリックス / NADPH oxidase / 細胞外マトリクス / 心不全 / 遺伝子組換えマウス / ゲノム編集 / 心筋細胞 / 心線維芽細胞 / ROS / うつ / 不安 / ストレス / 精神疾患 / 循環器 / 肝臓 / 高血圧症 / 酸化ストレス / 腎臓 / 細胞老化 / 糖尿病 / 慢性腎臓病 / メタボリックシンドローム / チャネル / 不整脈 / 循環器・高血圧 / スプラウティング / 蛋白質分解系 / ミエリン関連蛋白質 / 脱髄 / 脊髄後根 / リゾボスファチジン酸 / アロディニア / 神経因性疼痛 Less
  • Research Projects

    (13 results)
  • Research Products

    (25 results)
  • Co-Researchers

    (12 People)
  •  多疾患に共通するmyelopoiesis誘導機構の解明とその治療戦略Principal Investigator

    • Principal Investigator
      松本 みさき
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Wakayama Medical University
  •  New therapeutic strategies for diastolic heart failure using extracellular matrix

    • Principal Investigator
      Iwata Kazumi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Differential role of NADPH oxidase in autoimmune diseasesPrincipal Investigator

    • Principal Investigator
      Matsumoto Misaki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Identification of novel therapeutic targets for cardiac fibrosis

    • Principal Investigator
      Iwata Kazumi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Role of NOX1/NADPH oxidase in acquired immunityPrincipal Investigator

    • Principal Investigator
      Matsumoto Misaki
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  A novel role for Nox1/NADPH oxidase in cardiac fibrosis

    • Principal Investigator
      IWATA KAZUMI
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The involvement of oxidative stress in high fat diet-induced nonalcoholic steatohepatitisPrincipal Investigator

    • Principal Investigator
      Matsumoto Misaki
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Identification of NOX1-expressing cells and pathophysiological roles of NOX1 in colonPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Misaki
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  Development of a new NOX1-targeted strategy for the treatment of metabolic syndrome

    • Principal Investigator
      Yabe Chihiro
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  The role of ROS-generating enzyme on the psychiatric disorders

    • Principal Investigator
      Masakazu Ibi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurochemistry/Neuropharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  A study on the role of NOX1/NADPH oxidase in cardiac arrhythmia

    • Principal Investigator
      YABE Chihiro
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General pharmacology
    • Research Institution
      Kyoto Prefectural University of Medicine
  •  ジフテリア毒素による有髄Aδ線維ターゲティングと高解像度アレイによる機能分子同定Principal Investigator

    • Principal Investigator
      松本 みさき
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      疼痛学
    • Research Institution
      Kyoto Prefectural University of Medicine
      Nagasaki University
  •  神経因性疼痛の原因分子リゾホスファチジン酸による脱髄とミエリン蛋白質分解機構

    • Principal Investigator
      植田 睦美
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      疼痛学
    • Research Institution
      Nagasaki University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2012 2010 Other

All Journal Article Presentation

  • [Journal Article] Bortezomib is an effective enhancer for chemical probe-dependent superoxide detection.2022

    • Author(s)
      Matsumoto M, Sawada H, Iwata K, Ibi M, Asaoka N, Katsuyama M, Shintani-Ishida K, Ikegaya H, Takegami S, Umemura A, Yabe-Nishimura C.
    • Journal Title

      Front Med (Lausanne)

      Volume: 9 Pages: 941180-941180

    • DOI

      10.3389/fmed.2022.941180

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07087, KAKENHI-PROJECT-21K06523, KAKENHI-PROJECT-20K07294, KAKENHI-PROJECT-20K10558
  • [Journal Article] NOX1/NADPH oxidase is involved in the LPS-induced exacerbation of collagen-induced arthritis2021

    • Author(s)
      Matsumoto M, Liu J, Iwata K, Ibi M, Asaoka N, Zhang X, Katsuyama M, Matsuda M, Nabe T, Scroder K, Yabe-Nishimura C.
    • Journal Title

      J Pharmacol Sci

      Volume: 146 (2) Issue: 2 Pages: 88-97

    • DOI

      10.1016/j.jphs.2021.01.009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07294, KAKENHI-PROJECT-20K07087
  • [Journal Article] NOX1/NADPH oxidase in bone marrow-derived cells modulates intestinal barrier function2020

    • Author(s)
      Liu J, Iwata K, Zhu K, Matsumoto M, Asaoka N, Zhang X, Ibi M, Katsuyama M, Tsutsui M, Kato S, and Yabe-Nishimura C
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 147 Pages: 90-101

    • DOI

      10.1016/j.freeradbiomed.2019.12.009

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08657, KAKENHI-PROJECT-18K06898
  • [Journal Article] NOX1/ NADPH oxidase regulates the expression of multidrug resistance‐associated protein 1 and maintains intracellular glutathione levels2019

    • Author(s)
      Wen Xiaopeng、Iwata Kazumi、Ikuta Keiko、Zhang Xueqing、Zhu Kai、Ibi Masakazu、Matsumoto Misaki、Asaoka Nozomi、Liu Junjie、Katsuyama Masato、Yabe‐Nishimura Chihiro
    • Journal Title

      The FEBS Journal

      Volume: 286 Issue: 4 Pages: 678-687

    • DOI

      10.1111/febs.14753

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06898
  • [Journal Article] The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease.2018

    • Author(s)
      Matsumoto M, Zhang J, Zhang X, Liu J, Jiang JX, Yamaguchi K, Taruno A, Katsuyama M, Iwata K, Ibi M, Cui W, Matsuno K, Marunaka Y, Itoh Y, Torok NJ, Yabe-Nishimura C.
    • Journal Title

      Free Radic Biol Med.

      Volume: 115 Pages: 412-420

    • DOI

      10.1016/j.freeradbiomed.2017.12.019

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08601, KAKENHI-PROJECT-16K15181, KAKENHI-PROJECT-15K06776
  • [Journal Article] Up-regulation of NOX1/NADPH oxidase following drug-induced myocardial injury promotes cardiac dysfunction and fibrosis2018

    • Author(s)
      Iwata Kazumi、Matsuno Kuniharu、Murata Ayumi、Zhu Kai、Fukui Hitomi、Ikuta Keiko、Katsuyama Masato、Ibi Masakazu、Matsumoto Misaki、Ohigashi Makoto、Wen Xiaopeng、Zhang Jia、Cui Wenhao、Yabe-Nishimura Chihiro
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 120 Pages: 277-288

    • DOI

      10.1016/j.freeradbiomed.2018.03.053

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K08239, KAKENHI-PROJECT-15K06776
  • [Journal Article] NADPH oxidase NOX1 is involved in activation of protein kinase C and premature senescence in early stage diabetic kidney2015

    • Author(s)
      Kai Z., Kakehi T., Matsumoto M. et al.
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 83 Pages: 21-30

    • DOI

      10.1016/j.freeradbiomed.2015.02.009

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24390063, KAKENHI-PROJECT-24500445, KAKENHI-PUBLICLY-25116521
  • [Journal Article] NADPH oxidase NOX1 id involved in activation of protein kinase C and premature senescence in early stage diabetic kidney2015

    • Author(s)
      Kai Z., Kakehi T., Matsumoto M., et al.
    • Journal Title

      Free Radical Biology and Medicine

      Volume: 83 Pages: 21-30

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24390063
  • [Journal Article] Clioquinol Increases the Expression of VGF, a Neuropeptide Precursor, Through Induction of c-Fos Expression2014

    • Author(s)
      Katsuyama M, Ibi M, Matsumoto M, Iwata K, Ohshima Y, Yabe-Nishimura C
    • Journal Title

      J Pharmacol Sci

      Volume: 124 Issue: 4 Pages: 427-432

    • DOI

      10.1254/jphs.13271FP

    • NAID

      130003391513

    • ISSN
      1347-8613, 1347-8648
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24500445, KAKENHI-PUBLICLY-25116521
  • [Journal Article] Characterization of N-glycosylation sites on the extracellular domain of NOX1/NADPH oxidase.2014

    • Author(s)
      Matsumoto M, Katsuyama M, Iwata K, Ibi M, Zhang J, Zhu K, Nauseef WM, Yabe-Nishimura C.
    • Journal Title

      Free Radic Biol Med.

      Volume: 68 Pages: 196-204

    • DOI

      10.1016/j.freeradbiomed.2013.12.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25860191, KAKENHI-PROJECT-24500445, KAKENHI-PUBLICLY-25116521
  • [Journal Article] Deficiency of NOX1/nicotinamide adenine dinucleotide phosphate, reduced form oxidase leads to pulmonary vascular remodeling.2014

    • Author(s)
      Iwata K, Ikami K, Matsuno K, Yamashita T, Shiba D, Ibi M, Matsumoto M, Katsuyama M, Cui W, Zhang J, Zhu K, Takei N, Kokai Y, Ohneda O, Yokoyama T, Yabe-Nishimura C.
    • Journal Title

      Arterioscler Thromb Vasc Biol.

      Volume: 34(1) Issue: 1 Pages: 110-119

    • DOI

      10.1161/atvbaha.113.302107

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24790198, KAKENHI-PROJECT-24790308, KAKENHI-PROJECT-26870464, KAKENHI-PROJECT-24500445, KAKENHI-PUBLICLY-25116521
  • [Journal Article] Clioquinol induces DNA double-strand breaks, activation of ATM, and subsequent activation of p532012

    • Author(s)
      Katsuyama M, Iwata K, Ibi M, Matsuno K, Matsumoto M, Yabe-Nishimura C
    • Journal Title

      Toxicology

      Volume: 299 Issue: 1 Pages: 55-59

    • DOI

      10.1016/j.tox.2012.05.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500445
  • [Journal Article] NOX1/NADPH oxidase is involved in endotoxin-induced cardiomyocyte spoptosis.2012

    • Author(s)
      Matsuno K, Iwata K, Matsumoto M, Katsuyama M, Cui W, Murata A, Nakamura H, Ibi M, Ikami K, Zhang J, Matoba S, Jin D, Takai S, Matsubara H, Matsuda N, Yabe-Nishimura C
    • Journal Title

      Free Radic Biol Med

      Volume: 53 Issue: 9 Pages: 1718-1728

    • DOI

      10.1016/j.freeradbiomed.2012.08.590

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24500445, KAKENHI-PROJECT-24590336
  • [Journal Article] Parathyroid hormone 2 receptor is a functional marker of nociceptive my elinated fibers responsible for neuropathic pain2010

    • Author(s)
      Misaki Matsumoto
    • Journal Title

      Journal of Neurochemistry 112

      Pages: 521-530

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21600008
  • [Presentation] ドキソルビシンによる心筋細胞傷害におけるNOX1/NADPHオキシダーゼの役割.2022

    • Author(s)
      深津陽大,岩田和実,松本みさき,天ヶ瀬紀久子
    • Organizer
      次世代を担う若手のための創薬・医療薬理シンポジウム
    • Data Source
      KAKENHI-PROJECT-21K06805
  • [Presentation] ボルテゾミブ添加によるスーパーオキシドの高感度な検出法2022

    • Author(s)
      松本みさき、矢部千尋、楳村敦詩.
    • Organizer
      第96回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K07294
  • [Presentation] 実験的関節炎の発症に関わる活性酸素産生酵素NOX1/NADPHオキシダーゼ2021

    • Author(s)
      松本みさき、矢部千尋
    • Organizer
      第94回日本薬理学会年会
    • Data Source
      KAKENHI-PROJECT-20K07294
  • [Presentation] スーパーオキシド産生酵素NOX1/NADPH oxidase欠損マウスにおけるLPS惹起性コラーゲン誘発性関節炎の抑制2021

    • Author(s)
      松本みさき
    • Organizer
      第22回免疫サマースクール2021
    • Data Source
      KAKENHI-PROJECT-20K07294
  • [Presentation] NASHの発症に関わる活性酸素産生酵素NADPHオキシダーゼ2017

    • Author(s)
      松本みさき、張嘉、張雪晴、矢部千尋
    • Organizer
      第90回日本薬理学会年会
    • Place of Presentation
      長崎
    • Year and Date
      2017-03-16
    • Data Source
      KAKENHI-PROJECT-15K18993
  • [Presentation] A potential role for Nox1 isoform of NADPH oxidase in the development of nonalcoholic steatohepatitis.2016

    • Author(s)
      M. Matsumoto, J. Zhang, X. Zhang, C. Yabe-Nishimura.
    • Organizer
      SfRBM's 23rd Annual Meeting (SfRBM/SFRRI 2016)
    • Place of Presentation
      CA, USA
    • Year and Date
      2016-11-19
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18993
  • [Presentation] 非アルコール性脂肪性肝炎モデルの肝類洞における酸化ストレスの解析2016

    • Author(s)
      松本みさき、張 嘉、張 雪晴、矢部 千尋
    • Organizer
      第59回日本糖尿病学会
    • Place of Presentation
      京都
    • Year and Date
      2016-05-20
    • Data Source
      KAKENHI-PROJECT-15K18993
  • [Presentation] 非アルコール性脂肪性肝炎モデルにおける活性酸素種産生酵素NOX1の役割2015

    • Author(s)
      矢部 千尋、松本 みさき、張 嘉
    • Organizer
      第58回日本糖尿病学会(第2回肝臓病と糖尿病・代謝研究会)
    • Place of Presentation
      山口
    • Year and Date
      2015-05-23
    • Data Source
      KAKENHI-PROJECT-15K18993
  • [Presentation] 非アルコール性脂肪性肝炎モデルにおけるスーパーオキシド産生酵素NOX1の役割2014

    • Author(s)
      松本みさき、張嘉、矢部千尋
    • Organizer
      第126回日本薬理学会近畿部会
    • Place of Presentation
      和歌山
    • Year and Date
      2014-10-24
    • Data Source
      KAKENHI-PROJECT-25860191
  • [Presentation] 新規抗NOX1抗体によるNOX1蛋白のN型糖鎖修飾の同定とその機能解析

    • Author(s)
      松本みさき,矢部千尋.
    • Organizer
      第86回日本生化学会大会
    • Place of Presentation
      横浜
    • Data Source
      KAKENHI-PROJECT-25860191
  • [Presentation] Analysis of the role of NOX1 in renal physiology.

    • Author(s)
      M. Matsumoto, M. Tanaka, C. Yabe-Nishimura.
    • Organizer
      Nox Family NADPH Oxidases, Gordon Research Conference
    • Place of Presentation
      Italy
    • Year and Date
      2014-05-18 – 2014-05-23
    • Data Source
      KAKENHI-PROJECT-25860191
  • 1.  IWATA Kazumi (60305571)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 5 results
  • 2.  YABE Chihiro (70150571)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  CHOU Ka (50599222)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  植田 睦美 (30437834)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Masakazu Ibi (10336539)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 6.  植田 弘師 (00145674)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  松野 邦晴 (50420708)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  沖垣 光彦 (10333197)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  天ヶ瀬 紀久子 (60278447)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 10.  浅岡 希美
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  筒井 正人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  芝 大
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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