Koike Ryoko 小池良子

… Alternative Names

KIKUCHI Ryoko 菊池良子

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Researcher Number	80535063
Affiliation (Current)	2025: 帝京大学, 医学部, 助手
Affiliation (based on the past Project Information) *help	2017 – 2020: 帝京大学, 医学部, 助手 2016: 公益財団法人佐々木研究所, 附属研究所, 研究員(移行) 2015: 公益財団法人佐々木研究所, 附属研究所, 研究員 2013 – 2015: 公益財団法人佐々木研究所, その他部局等, 研究員 2012: 防衛医科大学校(医学教育部医学科進学課程及び専門課程、動物実験施設、共同利用研究, 医学教育部医学科専門課程, 助教 2012: 防衛医科大学校, 医学教育部医学科専門課程, 助教 2010 – 2011: 防衛医科大学校, 医学教育部・医学科専門課程, 助教
Review Section/Research Field	Principal Investigator Human pathology / Obstetrics and gynecology Except Principal Investigator Obstetrics and gynecology
Keywords	Principal Investigator パクリタキセル / 卵巣明細胞腺癌 / CTGF / 化学療法 / 抗がん剤耐性 / 卵巣明細胞癌 / NNMT / 蛍光標識2次元ディファレンシャルゲル電気泳動法 / 頭頸部扁平上皮癌 / 2D-DIGE … More / Mascot解析 / 蛍光標識二次元ディファレンスゲル電気泳動法 / 分子標的治療 / 化学療法の個別化 / 抗癌剤 / CTGF遺伝子 / 蛍光標識二次元電気泳動法 / 低酸素 / 抗癌剤感受性 / 卵巣癌 / 分子病理 … More Except Principal Investigator 子宮頸がん / PDT(光線力学的療法) / ガレクチン-4 / 子宮頸癌 / PDT / レザフィリン Less

Towards an improvement in the low sensitivity to chemotherapy in ovarian clear cell carcinomaPrincipal Investigator
- Principal Investigator
  
  Koike Ryoko
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Teikyo University
An attempt to improve low chemotherapy sensitivity of ovarian clear cell carcinomaPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Ryoko
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Sasaki Foundation
Investigation of cell characteristics of cancer metastasis and drug resistance using gynecological cancer's specific sugar chains.
- Principal Investigator
  
  SAKAMOTO Masaru
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Sasaki Foundation
Analysis of CTGF,the new candidate of the tumor suppressor gene in ovarian cancer, for personalized anti-cancer therapyPrincipal Investigator
- Principal Investigator
  
  KIKUCHI Ryoko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Human pathology
- Research Institution
  National Defense Medical College

All 2019 2015 2014 2012 2011 Other

All Journal Article Presentation Other

[Journal Article] The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer.2019
- Author(s)
  Fukui S, Nagasaka K, Miyagawa Y, Kikuchi-Koike R, Kawata Y, Kanda R, Ichinose T, Sugihara T, Hiraike H, Wada-Hiraike O, Sasajima Y, Ayabe T
- Journal Title
  
  Oncotarget
  
  Volume: 10 Issue: 57 Pages: 5932-5948
- DOI
  10.18632/oncotarget.27219
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08709, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-19K09834
[Journal Article] Array comparative genomic hybridization analysis discloses chromosome copy number alterations as indicators of patient outcome in lymph node-negative breast cancer2019
- Author(s)
  Ryoko Kikuchi-Koike1,2,3, Kazunori Nagasaka1§, Hitoshi Tsuda2, Yasuyuki Ishii4, Masaru Sakamoto3,5,6, Yoshihiro Kikuchi7, Shiho Fukui1, Yuko Miyagawa1, Haruko Hiraike1, Takayuki Kobayashi2, Takayuki Kinoshita8, Yae Kanai9, Tatsuhiro Shibata10, Issei Imoto11, Johji Inazawa12, Osamu Matsubara2, Takuya Ayabe1
- Journal Title
  
  BMC cancer
  
  Volume: 9 Pages: 9-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08709
[Journal Article] カボザンチニブの併用は再発子宮平滑筋肉腫へのテモゾロミドとペパシズマブの治療効果を高める．2015
- Author(s)
  池田さやか, 工藤一弥, 佐々木直樹, 後藤友子, 高野政志, 菊池良子, 坂本優, 喜多恒和, 菊池義公
- Journal Title
  
  日本婦人科腫瘍学会雑誌
  
  Volume: 33 Pages: 564-564
- Data Source
  KAKENHI-PROJECT-25462623
[Journal Article] カボザンチニブの併用は再発子宮平滑筋肉腫へのテモゾロミドとペパシズマブの治療効果を高める．2015
- Author(s)
  池田さやか, 工藤一弥, 佐々木直樹, 後藤友子, 高野政志, 菊池良子, 坂本優, 喜多恒和, 菊池義公.
- Journal Title
  
  日本婦人科腫瘍学会雑誌
  
  Volume: 33 Pages: 564-564
- Data Source
  KAKENHI-PROJECT-25871147
[Journal Article] The expression and clinical significance of connective tissue growth factor in advanced head and neck squamous cell cancer.2014
- Author(s)
  Kikuchi R, Kikuchi Y, Tsuda H, Maekawa H, Kozaki KI, Imoto I, Tamai S, Shiotani A, Iwaya K, Sakamoto M, Sekiya T, Matsubara O
- Journal Title
  
  Human Cell
  
  Volume: 印刷中 Issue: 3 Pages: 121-128
- DOI
  10.1007/s13577-014-0092-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25871147, KAKENHI-PROJECT-26293067, KAKENHI-PROJECT-26293304, KAKENHI-PROJECT-26670815
[Journal Article] Stathmin is involved in the cooperativeeffect of Zoledronic acid and gefitinib onbone homing breast cancer cells in vitro2012
- Author(s)
  Oda M, Iwaya K, Kikuchi R, Kobayashi T,Yoneda T, Nishikawa K, Matsubara O, KohnoN
- Journal Title
  
  Journal of Bone Oncology
  
  Volume: Vol. 1 Pages: 40-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790364
[Journal Article] Proteome analysis of ovarian cancer cell lines under hypoxic condition by two-dimensional difference gel electrophoresis (2D-DIGE) [abstract].2012
- Author(s)
  Kikuchi R, Iwaya K, Matsubara O
- Journal Title
  
  In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research
  
  Volume: 1 Pages: 462-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790364
[Journal Article] Stathmin is involved in the cooperative effect of Zoledronic acid and gefitinib on bone homing breast cancer cells in vitro.2012
- Author(s)
  Oda M, Iwaya K, Kikuchi R, Kobayashi T, Yoneda T, Nishikawa K, Matsubara O, Kohno N
- Journal Title
  
  Journal of Bone Oncology
  
  Volume: 1 Pages: 40-46
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790364
[Journal Article] Proteomeanalysis of ovarian cancer cell lines underhypoxic condition by two-dimensionaldifference gel electrophoresis (2D-DIGE)[abstract]2012
- Author(s)
  Kikuchi R, Iwaya K, Matsubara O
- Journal Title
  
  Proceedings of the 103rdAnnual Meeting of the American Associationfor Cancer Research Research; 2012 Mar 31-Apr 4;Chicago, Illinois. Philadelphia (PA): AACR
  
  Pages: 462-462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790364
[Journal Article] Weekly administrationof temsirolimus for heavily pretreatedpatients with clear cell carcinoma of theovary: a report of six cases2011
- Author(s)
  Takano M, Kikuchi Y, Kudoh K, Goto T,Furuya K, Kikuchi R, Kita T, Fujiwara K,Shiozawa T, Aoki D
- Journal Title
  
  International Journal of ClinicalOncology
  
  Volume: Vol. 16 Pages: 605-609
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790364
[Journal Article] Effects of bevacizumaband pegylated liposomal doxorubicin for thepatients with recurrent or refractoryovarian cancers2011
- Author(s)
  Kudoh K, Takano M, Kouta H, Kikuchi R,Kita T, Miyamoto M, Watanabe A, Kato M,Goto T, Kikuchi Y
- Journal Title
  
  Gynecologic Oncology
  
  Volume: Vol.122 Pages: 233-237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790364
[Presentation] Synergistic effects of cabozantinib to temozolomide and bevacizumab in patients with heavily pretreated relapsed uterine leiomyosarcoma.2015
- Author(s)
  Sayaka Ikeda, Kazuya Kudoh, Naoki Sasaki, Masashi Takano, Tomoko Goto, Ryoko Kikuchi, Masaru Sakamoto, Tsunekazu Kita, Nobuyuki Susumu, Daisuke Aoki, Hiroko Kouta, Yoshihiro Kikuchi
- Organizer
  The 51th Annual Meeting of the American Society of Clinical Oncology (ASCO)
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25462623
[Presentation] Synergistic effects of cabozantinib to temozolomide and bevacizumab in patients with heavily pretreated relapsed uterine leiomyosarcoma.2015
- Author(s)
  Sayaka Ikeda, Kazuya Kudoh, Naoki Sasaki, Masashi Takano, Tomoko Goto, Ryoko Kikuchi, Masaru Sakamoto, Tsunekazu Kita, Nobuyuki Susumu, Daisuke Aoki, Hiroko Kouta, Yoshihiro Kikuchi
- Organizer
  The 51th Annual Meeting of the American Society of Clinical Oncology (ASCO)
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25871147
[Presentation] PDT for CIN3 and early stage cervical cancer might be superior therapy for fertility preservation in comparison with conization.2015
- Author(s)
  Masaru Sakamoto, Takafumi Kuroda, Keiji Morimoto, Ryoko Kikuchi, Kiyohiko Miyake, Yasuko Koyamatsu, Tadao Tanaka and Aikou Okamoto.
- Organizer
  第67回日本産科婦人科学会学術講演会
- Place of Presentation
  横浜
- Year and Date
  2015-04-09
- Data Source
  KAKENHI-PROJECT-25462623
[Presentation] Weekly administration of bevacizumab, eribulin and oxalilplatin in patients with platinum-resistant ovarian carcinomas: a phase II study with biomarker analysis.2015
- Author(s)
  Kazuya Kudoh, Yuji Ikeda, Masashi Takano, Hiroko Kouta, Tsunekazu Kita, Ryoko Kikuchi, Morikazu Miyamoto, Tomoyuki Yoshikawa, Tomoko Goto, Kenichi Furuya, Yutaka Tamada, Arata Suga, Yoshihiro Kikuchi
- Organizer
  The 51th Annual Meeting of the American Society of Clinical Oncology (ASCO)
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25871147
[Presentation] Combination therapy with temsirolimus and trabectedin for recurrent clear cell carcinoma of the ovary: A phase II study with biomarker analysis.2015
- Author(s)
  Masashi Takano, Hiroko Kouta, Kazuya Kudoh, Tsunekazu Kita, Ryoko Kikuchi, Morikazu Miyamoto, Tomoyuki Yoshikawa, Tomoko Goto, Kenichi Furuya, Yutaka Tamada, Arata Suga, Yoshihiro Kikuchi
- Organizer
  The 51th Annual Meeting of the American Society of Clinical Oncology (ASCO)
- Place of Presentation
  Chicago, USA
- Year and Date
  2015-05-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25871147
[Presentation] 乳癌の骨転移に関与するstathmin の過剰発現と抗腫瘍効果との関連2012
- Author(s)
  小田美規, 岩屋啓一, 菊池良子, 山田公人, 海瀬博史, 松原修, 河野範男
- Organizer
  第20 回日本乳癌学会学術総会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22790364
[Presentation] 乳癌の骨転移に関与するstathminの過剰発現と抗腫瘍効果との関連2012
- Author(s)
  小田美規、岩屋啓一、菊池良子、山田公人、海瀬博史、松原修、河野範男
- Organizer
  第20回日本乳癌学会学術総会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22790364
[Presentation] アレイCGH解析による卵巣癌関連遺伝子の同定と分子細胞診断への応用2012
- Author(s)
  菊池良子、井本逸勢、嘉屋隆介、三宅清彦、茂木真、坂本優、田中忠夫、岡本愛光、松原修、稲澤譲治
- Organizer
  日本臨床細胞学会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-22790364
[Presentation] 低酸素暴露下の卵巣癌細胞株のプロテオーム解析2012
- Author(s)
  菊池良子、岩屋啓一、松原修
- Organizer
  第101回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790364
[Presentation] 低酸素暴露下の卵巣癌細胞株のプロテオーム解析2012
- Author(s)
  菊池良子, 岩屋啓一, 松原修
- Organizer
  第101 回日本病理学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-22790364
[]
[]

1. SAKAMOTO Masaru (20260101)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
2. 綾部琢哉 (00272568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. 中川俊介 (70270874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Koike Ryoko 小池 良子

KIKUCHI Ryoko 菊池 良子

Research Projects

Research Products

Co-Researchers

Towards an improvement in the low sensitivity to chemotherapy in ovarian clear cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An attempt to improve low chemotherapy sensitivity of ovarian clear cell carcinomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of cell characteristics of cancer metastasis and drug resistance using gynecological cancer's specific sugar chains.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of CTGF,the new candidate of the tumor suppressor gene in ovarian cancer, for personalized anti-cancer therapyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The proteasome deubiquitinase inhibitor bAP15 downregulates TGF-β/Smad signaling and induces apoptosis via UCHL5 inhibition in ovarian cancer.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Array comparative genomic hybridization analysis discloses chromosome copy number alterations as indicators of patient outcome in lymph node-negative breast cancer2019

Author(s)

Journal Title

Data Source

[Journal Article] カボザンチニブの併用は再発子宮平滑筋肉腫へのテモゾロミドとペパシズマブの治療効果を高める．2015

Author(s)

Journal Title

Data Source

[Journal Article] カボザンチニブの併用は再発子宮平滑筋肉腫へのテモゾロミドとペパシズマブの治療効果を高める．2015

Author(s)

Journal Title

Data Source

[Journal Article] The expression and clinical significance of connective tissue growth factor in advanced head and neck squamous cell cancer.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Stathmin is involved in the cooperativeeffect of Zoledronic acid and gefitinib onbone homing breast cancer cells in vitro2012

Author(s)

Journal Title

Data Source

[Journal Article] Proteome analysis of ovarian cancer cell lines under hypoxic condition by two-dimensional difference gel electrophoresis (2D-DIGE) [abstract].2012

Author(s)

Journal Title

Data Source

[Journal Article] Stathmin is involved in the cooperative effect of Zoledronic acid and gefitinib on bone homing breast cancer cells in vitro.2012

Author(s)

Journal Title

Data Source

[Journal Article] Proteomeanalysis of ovarian cancer cell lines underhypoxic condition by two-dimensionaldifference gel electrophoresis (2D-DIGE)[abstract]2012

Author(s)

Journal Title

Data Source

[Journal Article] Weekly administrationof temsirolimus for heavily pretreatedpatients with clear cell carcinoma of theovary: a report of six cases2011

Author(s)

Journal Title

Data Source

[Journal Article] Effects of bevacizumaband pegylated liposomal doxorubicin for thepatients with recurrent or refractoryovarian cancers2011

Author(s)

Journal Title

Data Source

[Presentation] Synergistic effects of cabozantinib to temozolomide and bevacizumab in patients with heavily pretreated relapsed uterine leiomyosarcoma.2015

Author(s)

Organizer

Place of Presentation

Year and Date

Koike Ryoko 小池良子

KIKUCHI Ryoko 菊池良子