Kondo Takayuki 近藤孝之

Researcher Number	80536566
Other IDs
Affiliation (Current)	2025: 京都大学, iPS細胞研究所, 特定拠点講師 2025: 国立研究開発法人理化学研究所, バイオリソース研究センター, 客員研究員 2025: 国立研究開発法人理化学研究所, 革新知能統合研究センター, 客員研究員
Affiliation (based on the past Project Information) *help	2019 – 2023: 京都大学, iPS細胞研究所, 特定拠点講師 2018: 京都大学, iPS細胞研究所, 特定拠点助教 2017: 京都大学, 医学(系)研究科(研究院), 特定拠点助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Neurology Except Principal Investigator Studies on the Super-Aging Society / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator アストロサイト / アルツハイマー病 / 老化 / スクリーニング / グリア細胞 / 創薬 / iPS細胞 / Astrocyte / 疾患モデル / GWAS … More / 孤発性 / 再生医学 / 発生・分化 / 脳神経疾患 / 三次元 / 疾患モデリング / iPS細胞 / / オルガノイド / 大脳皮質 / 三次元培養 / 分化誘導 / 神経細胞 … More Except Principal Investigator ALS / iPS細胞 / アルツハイマー病 / 超高齢社会 / 神経変性 / deep learning / Deep learning / データサイエンス / 診断 / 超早期病態 / Deep Learning / 神経再生 / 細胞移植 / ダイレクトリプログラミング / ウイルスベクター / 再生医療 / 運動神経細胞 / 生体内ダイレクトリプログラミング Less

患者アストロサイトとハイブリッドマウスによるアルツハイマー病病態の解明Principal Investigator
- Principal Investigator
  
  近藤孝之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyoto University
Modeling Alzheimer's disease with patient astrocytePrincipal Investigator
- Principal Investigator
  
  Kondo Takayuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Kyoto University
In vivo reprogramming for ALS regenerative therapy
- Principal Investigator
  
  Haruhisa Inoue
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Kyoto University
Imaging studies of neurodegeneration by deep learning
- Principal Investigator
  
  Haruhisa Inoue
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Studies on the Super-Aging Society
- Research Institution
  Kyoto University
Building 3D platform of patient iPS cells for drug developmentPrincipal Investigator
- Principal Investigator
  
  Kondo Takayuki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  Kyoto University

All 2024 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Induced pluripotent stem cell‐based assays recapture multiple properties of human astrocytes2024
- Author(s)
  Nonaka Hideki、Kondo Takayuki、Suga Mika、Yamanaka Ryu、Sagara Yukako、Tsukita Kayoko、Mitsutomi Naoko、Homma Kengo、Saito Ryuta、Miyoshi Fumihiko、Ohzeki Hiromitsu、Okuyama Masahiro、Inoue Haruhisa
- Journal Title
  
  Journal of Cellular and Molecular Medicine
  
  Volume: 28 Issue: 7
- DOI
  10.1111/jcmm.18214
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06927
[Journal Article] Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients2022
- Author(s)
  Kondo T, Hara N, Koyama S, Yada Y, Tsukita K, Nagahashi A, Ikeuchi T, Ishii K, Asada T, Arai T, Yamada R, Japanese Alzheimer's Disease Neuroimaging Initiative (J-ADNI), Alzheimer’s Disease Neuroimaging Initiative (ADNI), Inoue H
- Journal Title
  
  Nature Aging
  
  Volume: 2 Issue: 2 Pages: 125-139
- DOI
  10.1038/s43587-021-00158-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02807, KAKENHI-PROJECT-20K07830, KAKENHI-PROJECT-20K16599
[Journal Article] CDiP technology for reverse engineering of sporadic Alzheimer’s disease2022
- Author(s)
  Kondo Takayuki、Yada Yuichiro、Ikeuchi Takeshi、Inoue Haruhisa
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 68 Issue: 3 Pages: 231-235
- DOI
  10.1038/s10038-022-01047-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16599
[Journal Article] Metabolites of soil microorganisms modulate amyloid β production in Alzheimer’s neurons2022
- Author(s)
  Kondo T, Yamamoto T, Okayama K, Narumi H, Inoue H
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 2690-2690
- DOI
  10.1038/s41598-022-06513-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02807, KAKENHI-PROJECT-20K16599
[Journal Article] Evaluation of Toxic Amyloid β42 Oligomers in Rat Primary Cerebral Cortex Cells and Human iPS-derived Neurons Treated with 10-Me-Aplog-1, a New PKC Activator2020
- Author(s)
  Murakami Kazuma、Yoshimura Mayuko、Nakagawa Shota、Kume Toshiaki、Kondo Takayuki、Inoue Haruhisa、Irie Kazuhiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 4 Pages: 1179-1179
- DOI
  10.3390/ijms21041179
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07119, KAKENHI-PLANNED-17H06405, KAKENHI-PROJECT-17K16121
[Journal Article] Generation of a human induced pluripotent stem cell line derived from a Parkinson's disease patient carrying SNCA duplication2020
- Author(s)
  Hidefumi Suzuki et al.
- Journal Title
  
  Stem Cell Research
  
  Volume: 45 Pages: 101828-101828
- DOI
  10.1016/j.scr.2020.101828
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07986, KAKENHI-PROJECT-20K07883, KAKENHI-PROJECT-17K16121, KAKENHI-PROJECT-18H02717, KAKENHI-PROJECT-18K18452
[Journal Article] Generation of a human induced pluripotent stem cell line, BRCi009-A, derived from a patient with glycogen storage disease type 1a2020
- Author(s)
  Katagami Yukimi、Kondo Takayuki、Suga Mika、Yada Yuichiro、Imamura Keiko、Shibukawa Ran、Sagara Yukako、Okanishi Yasue、Tsukita Kayoko、Hirayama Kenji、Era Takumi、Inoue Haruhisa
- Journal Title
  
  Stem Cell Research
  
  Volume: 49 Pages: 102095-102095
- DOI
  10.1016/j.scr.2020.102095
- NAID
  120006980737
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02717, KAKENHI-PROJECT-18K18452
[Journal Article] Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes2019
- Author(s)
  Suga Mika、Kondo Takayuki、Inoue Haruhisa
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 16 Pages: 3862-3862
- DOI
  10.3390/ijms20163862
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K18452, KAKENHI-PROJECT-18H02717
[Journal Article] iPSC-Based Compound Screening and In?Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer’s Disease2017
- Author(s)
  Kondo Takayuki、Imamura Keiko、Funayama Misato、Tsukita Kayoko、Miyake Michiyo、Ohta Akira、Woltjen Knut、Nakagawa Masato、Asada Takashi、Arai Tetsuaki、Kawakatsu Shinobu、Izumi Yuishin、Kaji Ryuji、Iwata Nobuhisa、Inoue Haruhisa
- Journal Title
  
  Cell Reports
  
  Volume: 21 Issue: 8 Pages: 2304-2312
- DOI
  10.1016/j.celrep.2017.10.109
- NAID
  120006366743
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16121
[Presentation] Generation of a human induced pluripotent stem cell line derived from a Parkinson’s disease patient with SNCA duplication2021
- Author(s)
  Hidefumi Suzukia, Naohiro Egawa, Takayuki Kondo, Keiko Imamuraa, Takako Enami, Kayoko Tsukita, Mika Suga, Ran Shibukawa, Yasue Okanishi, Tsuyoshi Uchiyama, Haruhisa Inoue, Ryosuke Takahashi
- Organizer
  第14回パーキンソン病・運動障害疾患コングレス
- Invited
- Data Source
  KAKENHI-PROJECT-18K18452
[Presentation] Generation of a human induced pluripotent stem cell line derived from a Parkinson’s disease patient with SNCA duplication（ポスター発表）2021
- Author(s)
  Hidefumi Suzukia, Naohiro Egawa, Takayuki Kondo, Keiko Imamuraa, Takako Enami, Kayoko Tsukita, Mika Suga, Ran Shibukawa, Yasue Okanishi, Tsuyoshi Uchiyama, Haruhisa Inoue, Ryosuke Takahashi
- Organizer
  第14回パーキンソン病・運動障害疾患コングレス
- Data Source
  KAKENHI-PROJECT-18H02717
[Presentation] Generation of a human induced pluripotent stem cell line derived from a Parkinson’s disease patient demonstrating SNCA duplication（ポスター発表）2020
- Author(s)
  Hidefumi Suzukia, Naohiro Egawa, Takayuki Kondo, Keiko Imamuraa, Takako Enami, Kayoko Tsukita, Mika Suga, Ran Shibukawa, Yasue Okanishi, Tsuyoshi Uchiyama, Haruhisa Inoue, Ryosuke Takahashi
- Organizer
  第43回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02717
[Presentation] Generation of a human induced pluripotent stem cell line derived from a Parkinson’s disease patient demonstrating SNCA duplication（ポスター発表）2020
- Author(s)
  Hidefumi Suzukia, Naohiro Egawa, Takayuki Kondo, Keiko Imamuraa, Takako Enami, Kayoko Tsukita, Mika Suga, Ran Shibukawa, Yasue Okanishi, Tsuyoshi Uchiyama, Haruhisa Inoue, Ryosuke Takahashi
- Organizer
  第43回日本神経科学大会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K18452
[Presentation] アルツハイマー病患者の神経細胞を用いた化合物スクリーニングと“in vitro trial”2018
- Author(s)
  近藤孝之
- Organizer
  第37回日本認知症学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16121

1. Haruhisa Inoue (70332327)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
2. 今村恵子 (90379652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
3. 矢田祐一郎 (80805797)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 久米利明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kondo Takayuki 近藤 孝之

Research Projects

Research Products

Co-Researchers

患者アストロサイトとハイブリッドマウスによるアルツハイマー病病態の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Modeling Alzheimer's disease with patient astrocytePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In vivo reprogramming for ALS regenerative therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Imaging studies of neurodegeneration by deep learning

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Building 3D platform of patient iPS cells for drug developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Induced pluripotent stem cell‐based assays recapture multiple properties of human astrocytes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dissection of the polygenic architecture of neuronal Aβ production using a large sample of individual iPSC lines derived from Alzheimer’s disease patients2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CDiP technology for reverse engineering of sporadic Alzheimer’s disease2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metabolites of soil microorganisms modulate amyloid β production in Alzheimer’s neurons2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Evaluation of Toxic Amyloid β42 Oligomers in Rat Primary Cerebral Cortex Cells and Human iPS-derived Neurons Treated with 10-Me-Aplog-1, a New PKC Activator2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of a human induced pluripotent stem cell line derived from a Parkinson's disease patient carrying SNCA duplication2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of a human induced pluripotent stem cell line, BRCi009-A, derived from a patient with glycogen storage disease type 1a2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Modeling Neurological Disorders with Human Pluripotent Stem Cell-Derived Astrocytes2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] iPSC-Based Compound Screening and In?Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer’s Disease2017

Author(s)

Journal Title

DOI

NAID

Kondo Takayuki 近藤孝之