Kiriyama Takao 桐山敬生

Researcher Number	80571025
Other IDs
Affiliation (Current)	2025: 奈良県立医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 奈良県立医科大学, 医学部, 講師 2019 – 2021: 奈良県立医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Basic Section 52020:Neurology-related
Keywords	Principal Investigator RAN翻訳 / リピート病 / オルガノイド / laser micro-irradiation / ポリペプチド / 脊髄小脳変性症 / 脳幹オルガノイド / DNA修復 / 核内封入体病 / ALS … More / RAN translation / C9orf72 / FUS / 脳オルガノイド / 筋萎縮性側索硬化症 / 非翻訳領域リピート病 / 神経変性疾患 Less

中枢性神経免疫疾患の免疫機構と遺伝的素因を合わせた病勢バイオマーカー確立Principal Investigator
- Principal Investigator
  
  桐山敬生
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Nara Medical University
Pathophysiological analysis of repeat disease causing neurodegenerative disease using human brain organoids.Principal Investigator
- Principal Investigator
  
  Kiriyama Takao
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nara Medical University

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response2022
- Author(s)
  Shiota Tomo、Nagata Riko、Kikuchi Sotaro、Nanaura Hitoki、Matsubayashi Masaya、Nakanishi Mari、Kobashigawa Shinko、Isozumi Noriyoshi、Kiriyama Takao、Nagayama Kazuaki、Sugie Kazuma、Yamashiro Yoshito、Mori Eiichiro
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10 Pages: 750829-750829
- DOI
  10.3389/fcell.2022.750829
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07978, KAKENHI-PROJECT-19K17043, KAKENHI-PROJECT-20K16583, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-21K15032, KAKENHI-PROJECT-22K07725, KAKENHI-PROJECT-21H03804, KAKENHI-PROJECT-19K08150, KAKENHI-PROJECT-23K21373, KAKENHI-PROJECT-21K19881
[Journal Article] C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers2021
- Author(s)
  Nanaura Hitoki、Aiba Yuichiro、Nakanishi Mari、Shiota Tomo、Hibino Masaki、Kikuchi Sotaro、Nagata Riko、Morikawa Naritaka、Iguchi Naohiko、Kiriyama Takao、Nagamori Shushi、Sugie Kazuma、Saio Tomohide、Yoshizawa Takuya、Mori Eiichiro et al.
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 5301-5301
- DOI
  10.1038/s41467-021-25560-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07978, KAKENHI-PROJECT-19K16060, KAKENHI-PROJECT-20K16583, KAKENHI-PROJECT-18H03984, KAKENHI-PROJECT-18H05229, KAKENHI-PROJECT-20H00327, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-20K06493, KAKENHI-PROJECT-20K06527, KAKENHI-PROJECT-20K06569, KAKENHI-PROJECT-20K06579, KAKENHI-PROJECT-21K15032, KAKENHI-PROJECT-19KK0071, KAKENHI-PROJECT-22KJ0024, KAKENHI-PLANNED-20H05925, KAKENHI-PROJECT-19H05648
[Journal Article] Gene expression profiles of human cerebral organoids identify PPAR pathway and PKM2 as key markers for oxygen-glucose deprivation and reoxygenation2021
- Author(s)
  Naoki Iwasa, Takeshi K. Matsui, Naohiko Iguchi, Kaoru Kinugawa, Naritaka Morikawa, Yoshihiko M. Sakaguchi, Tomo Shiota, Shinko Kobashigawa et. al.
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: － Pages: 605030-605030
- DOI
  10.3389/fncel.2021.605030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K23952, KAKENHI-PROJECT-19K07978, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-21K06758, KAKENHI-PROJECT-21K18273, KAKENHI-PROJECT-20H03680, KAKENHI-PROJECT-19K08150
[Journal Article] Brainstem organoids from human pluripotent stem cells2020
- Author(s)
  Nobuyuki Eura, Takeshi K. Matsui, Joachim Luginbuhl, Masaya Matsubayashi, Hitoki Nanaura, Tomo Shiota, Kaoru Kinugawa, Naohiko Iguchi, Takao Kiriyama, Canbin Zheng, Tsukasa Kouno, Yan Jun Lan, Pornparn Kongpracha, Pattama Wiriyasermkul, Yoshihiko M. Sakaguchi, Riko Nagata, Tomoya Komeda, Naritaka Morikawa, et al.
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: - Pages: 00538-00538
- DOI
  10.3389/fnins.2020.00538
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23952, KAKENHI-PROJECT-19K21306, KAKENHI-PROJECT-19K07318, KAKENHI-PROJECT-19K07978, KAKENHI-PROJECT-19K08150, KAKENHI-PROJECT-20K16583, KAKENHI-PROJECT-20K16606, KAKENHI-PROJECT-20H03199, KAKENHI-PROJECT-18K06524, KAKENHI-PROJECT-19K16925, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-18H02770
[Presentation] 脊髄性筋萎縮症 III型患者のヌシネルセン治療における多種項目による治療効果判定2019
- Author(s)
  桐山敬生、井口直彦、江浦信之、杉江和馬　奈良県立医科大学　脳神経内科学
- Organizer
  第37回神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07978

1. 杉江和馬 (60347549)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. 松井健 (90528605)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 七浦仁紀 (00827909)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 塩田智 (70837062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 井口直彦 (50838232)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 絹川薫

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Kiriyama Takao 桐山敬生

Research Projects

Research Products

Co-Researchers

中枢性神経免疫疾患の免疫機構と遺伝的素因を合わせた病勢バイオマーカー確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological analysis of repeat disease causing neurodegenerative disease using human brain organoids.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene expression profiles of human cerebral organoids identify PPAR pathway and PKM2 as key markers for oxygen-glucose deprivation and reoxygenation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Brainstem organoids from human pluripotent stem cells2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 脊髄性筋萎縮症 III型患者のヌシネルセン治療における多種項目による治療効果判定2019

Author(s)

Organizer

Data Source

Kiriyama Takao 桐山 敬生

Research Projects

Research Products

Co-Researchers

中枢性神経免疫疾患の免疫機構と遺伝的素因を合わせた病勢バイオマーカー確立Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiological analysis of repeat disease causing neurodegenerative disease using human brain organoids.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] C9orf72-Derived Proline:Arginine Poly-Dipeptides Modulate Cytoskeleton and Mechanical Stress Response2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] C9orf72-derived arginine-rich poly-dipeptides impede phase modifiers2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gene expression profiles of human cerebral organoids identify PPAR pathway and PKM2 as key markers for oxygen-glucose deprivation and reoxygenation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Brainstem organoids from human pluripotent stem cells2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 脊髄性筋萎縮症 III型患者のヌシネルセン治療における多種項目による治療効果判定2019

Author(s)

Organizer

Data Source

Kiriyama Takao 桐山敬生