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Mano Yasunobu  眞野 恭伸

ORCIDConnect your ORCID iD *help
Researcher Number 80577362
Other IDs
Affiliation (Current) 2026: 東京科学大学, 国際医工共創研究院, 特任助教
Affiliation (based on the past Project Information) *help 2026: 東京科学大学, 総合研究院, 特任助教
2020: 千葉大学, 未来医療教育研究センター, 特任助教
2017 – 2019: 千葉大学, 大学院医学研究院, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 50010:Tumor biology-related / Tumor biology
Keywords
Principal Investigator
細胞老化 / Notchシグナル / 癌 / TGF-βシグナル / 老化 / 早期細胞老化
  • Research Projects

    (3 results)
  • Research Products

    (9 results)
  • Co-Researchers

    (3 People)
  •  変形性膝関節症における軟骨及び免疫環境の恒常性破綻機構の解明Principal Investigator

    • Principal Investigator
      眞野 恭伸
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Institute of Science Tokyo
  •  Crosstalk between activated Notch and inactivated TGF-beta signaling in cancer cellsPrincipal Investigator

    • Principal Investigator
      MANO Yasunobu
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Chiba University
  •  Analysis of Ras/Raf-induced senescence by activated JAG1-Notch signalingPrincipal Investigator

    • Principal Investigator
      Mano Yasunobu
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Tumor biology
    • Research Institution
      Chiba University

All 2021 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer2021

    • Author(s)
      Sugiura Masahiro、Sato Hiroaki、Okabe Atsushi、Fukuyo Masaki、Mano Yasunobu、Shinohara Ken-ichi、Rahmutulla Bahityar、Higuchi Kosuke、Maimaiti Maihulan、Kanesaka Manato、Imamura Yusuke、Furihata Tomomi、Sakamoto Shinichi、Komiya Akira、Anzai Naohiko、Kanai Yoshikatsu、Luo Jun、Ichikawa Tomohiko、Kaneda Atsushi
    • Journal Title

      Translational Oncology

      Volume: 14 Issue: 1 Pages: 100915-100915

    • DOI

      10.1016/j.tranon.2020.100915

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16707, KAKENHI-PROJECT-20K18133, KAKENHI-PROJECT-19H03407, KAKENHI-PROJECT-19H03726, KAKENHI-PROJECT-20H03813, KAKENHI-PROJECT-18K16725, KAKENHI-PROJECT-19K16765, KAKENHI-PROJECT-20K09555
  • [Presentation] ウイルスがもたらすヘテロクロマチン破綻と新たなエピジェネティック発癌機構「エンハンサー侵襲」の発見2021

    • Author(s)
      岡部 篤史、Kie Kyon Huang、松坂 恵介、福世 真樹、星居 孝之、臼井 源紀、関 元昭、眞野 恭伸、Bahityar Rahmutulla、神田 輝、鈴木 孝禎、牛久 哲男、深山 正久、Patrick Tan、金田 篤志
    • Organizer
      第14回日本エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-19K16765
  • [Presentation] 中咽頭癌におけるメチル化遺伝子マーカーに基づく放射線療法の治療効果予測の検討2019

    • Author(s)
      黑川 友哉、中川 拓也、松坂 恵介、福世 真樹、眞野 恭伸、美馬 勝人、 三澤 清、花澤 豊行、金田 篤志
    • Organizer
      第30回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-19K16765
  • [Presentation] JAG1活性化細胞と正常細胞の共培養モデルを用いたRas/Raf誘導性早期細胞老化機構の解析2019

    • Author(s)
      眞野恭伸、福世真樹、岡部篤史、松坂恵介、山中遼太、油谷浩幸、金田篤志
    • Organizer
      第13回エピジェネティクス研究会年会
    • Data Source
      KAKENHI-PROJECT-19K16765
  • [Presentation] Identification of genetic/epigenetic alterations based on wild-type TP53 in high methylation gastric cancer2018

    • Author(s)
      Keisuke Matsusaka, Yasunobu Mano, Masaki Fukuyo, Masayuki Urabe, Rahmutulla Bahityar, Eriko Ikeda, Kazuko Kita, Hiroyuki Abe, Tetsuhiro Nemoto, Yasuyuki Seto, Masashi Fukayama, Atsushi Kaneda
    • Organizer
      The 77th Annual Meeting of the Japanese Cancer Association
    • Data Source
      KAKENHI-PROJECT-17K14983
  • [Presentation] 高メチル化胃癌におけるTP53変異非依存性ゲノム・エピゲノム異常の相乗効果2018

    • Author(s)
      松坂恵介、眞野恭伸、福世真樹、松田和暁、井上貴登、浦辺雅之、バハテヤリ・ラヒムトラ、池田英里子、阿部浩幸、喜多和子、瀬戸泰之、根本哲宏、深山正久、金田篤志
    • Organizer
      第29回日本消化器癌発生学会総会
    • Data Source
      KAKENHI-PROJECT-17K14983
  • [Presentation] Identification of unique genetic/epigenetic alteration in gastric cancer with high DNA methylation2017

    • Author(s)
      松坂恵介, 眞野恭伸、福世真樹、浦辺雅之、バハテヤリ・ラムヒトラ、油谷浩幸、瀬戸泰之、深山正久、金田篤志
    • Organizer
      第106回日本病理学会学術総会
    • Data Source
      KAKENHI-PROJECT-17K14983
  • [Presentation] 高メチル化胃癌における特異的なゲノム・エピゲノム変異の同定2017

    • Author(s)
      松坂恵介、眞野恭伸、福世真樹、浦辺雅之、油谷浩幸、深山正久、瀬戸泰之、金田篤志
    • Organizer
      第76回日本癌学会総会
    • Data Source
      KAKENHI-PROJECT-17K14983
  • [Presentation] JAG1-Notchシグナルの活性化を介したRas/Raf 誘導性早期細胞老化誘導機構2017

    • Author(s)
      眞野恭伸、福世真樹、山中遼太、岡部篤史、油谷浩幸、金田篤志
    • Organizer
      第40回分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17K14983
  • 1.  MATSUSAKA Keisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 2.  OKABE Atsushi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  FUKUYO Masaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results

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