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Sakai Hiroshi  坂井 寛

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SAKAI Hiroshi  坂井 寛

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Researcher Number 80611665
Affiliation (Current) 2025: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help 2020 – 2023: 九州大学, 医学研究院, 共同研究員
2014 – 2018: 九州大学, 医学研究院, 共同研究員
2013 – 2016: 九州大学, 医学(系)研究科(研究院), 共同研究員
2012: 九州大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 55020:Digestive surgery-related / Digestive surgery / Gastroenterology
Except Principal Investigator
Digestive surgery / Basic Section 55020:Digestive surgery-related / Gastroenterology
Keywords
Principal Investigator
膵癌 / 膵星細胞 / 癌間質相互作用 / 免疫微小環境 / 癌関連線維芽細胞 / 神経内分泌経路 / 腫瘍免疫 / 癌免疫微小環境 / 新規膵癌治療薬 / 新規癌治療薬 … More / ERAP2 / 新規治療薬 / 隔離膜 / 小胞体 / オートファジー / 膵オルガノイド / 癌微小環境 / バイオマーカー探索 / バイオマーカー検索 / 凍結組織アレイ / Energy Charge / MALDI-MSI / MRI / ナノカプセル / 早期診断 … More
Except Principal Investigator
膵癌 / 膵星細胞 / 癌間質相互作用 / 癌微小環境 / 微小転移 / 微小環境 / 4色発現マウス / 膵癌自然発生マウス / 播種 / 繊維芽細胞 / 膵臓癌 / Endo180 / 転移 / リモデリング / 腹膜播種 / 湿潤・転移 / 腹膜中皮細胞 / 間質細胞 / NPAS1 / DNAマイクロアレイ / 基質リモデリング / leading cell / 細胞外マトリックス / Normalization / Cancer micro environment / ECM remodeling / Leading cell / PSCs / Pancreatic cancer / TGFβ / 間質ニッチ / 発癌 / carcinogenesis / ニッチ / PDGFRβ / NG2 / 間質 / 腫瘍血管 / 血管内皮細胞 / 薬剤送達 / ペリサイト / 早期診断 / GNAS / 併存膵癌 / IPMN Less
  • Research Projects

    (11 results)
  • Co-Researchers

    (24 People)
  •  膵癌免疫微小環境-神経内分泌ネットワークの解明による免疫抑制解除への挑戦Principal Investigator

    • Principal Investigator
      坂井 寛
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kyushu University
  •  The origin of autophagosome derived from the endoplasmic reticulum with a focus on pancreatic stellate cell activation genesPrincipal Investigator

    • Principal Investigator
      SAKAI Hiroshi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Exploring a new regulation system of pancreatic cancer microenvironment using KPC confetti mice

    • Principal Investigator
      YASUI Takaharu
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55020:Digestive surgery-related
    • Research Institution
      Kyushu University
  •  Reproduction of the three dimensional coculture model reflecting pancreatic cancer microenvironment and metabolic analysis for the stromal remodeling by MALDI Mass-spectrometry Imaging.Principal Investigator

    • Principal Investigator
      SAKAI Hiroshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Relationship between stromal cells and pancreatic cancer cells in metastasis and dissemination

    • Principal Investigator
      MORIYAMA Taiki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Elucidation of leading cell and cancer microenvironment normalization of pancreatic cancer

    • Principal Investigator
      OHUCHIDA Kenoki
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  特異的膵星細胞の機能的分取による膵癌Desmoplasiaの解明

    • Principal Investigator
      藤原 謙次
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Early detection of pancreatic ductal adenocarcinoma based on the molecular assessment of pancreatic ductal adenocarcinoma concomitant with IPMN of the pancreas.

    • Principal Investigator
      OHTSUKA Takao
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Normalization of tumor vessels targeting pericytes; a new approach in treatment of pancreatic cancer

    • Principal Investigator
      SHIMAMOTO Masaya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyushu University
  •  Biological and clinical significance of niche during carcinogenesis in pancreatic cancer

    • Principal Investigator
      MIZUMOTO Kazuhiro
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Digestive surgery
    • Research Institution
      Kyushu University
  •  Development of nanocapsule containing MRI contrast agent effective for early diagnosis of pancreatic cancerPrincipal Investigator

    • Principal Investigator
      SAKAI Hiroshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Kyushu University
  • 1.  OHUCHIDA Kenoki (20452708)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  MIZUMOTO Kazuhiro (90253418)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 3.  江上 拓哉 (40507787)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  TOMINAGA Yohei (90304823)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  MORIYAMA Taiki (70586859)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  OHTSUKA Takao (20372766)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  TANAKA Masao (30163570)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  SHIMAMOTO Masaya (00457433)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  真鍋 達也 (60546464)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  藤田 逸人 (40611281)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  SHIRAHANE Kengo (10529803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  TAKAHATA Shunichi (50437779)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SHIMIZU Yukiko (10404021)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  村田 正治 (30304744)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  前山 良 (10611668)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  宮坂 義浩 (40507795)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  藤原 謙次 (10727184)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  久保 真 (60403961)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  中山 宏道 (80866773)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  YASUI Takaharu (60611283)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  木庭 遼 (10866776)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  阿部 俊也 (20722028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  永吉 絹子 (90761015)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  田村 公二 (90909582)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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