Igarashi Kentaro 五十嵐健太郎

Researcher Number	80622860
Other IDs
Affiliation (Current)	2022: 金沢大学, 医薬保健学総合研究科, 特任助教
Affiliation (based on the past Project Information) *help	2018 – 2022: 金沢大学, 医薬保健学総合研究科, 特任助教
Review Section/Research Field	Principal Investigator 0901:Oncology and related fields / Basic Section 56020:Orthopedics-related Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 患者由来腫瘍同所移植モデル / 骨肉腫 / シスプラチン耐性 / 高骨移行性 / 新規プラチナ製剤 / シスプラチン治療抵抗性 / 高骨親和性 / 患者由来腫瘍同所移植 / 薬剤耐性 / 骨親和性 / 患者由来組織同所性異種移植 / 軟部肉腫 / 個別化医療 … More Except Principal Investigator … More 骨肉腫 / 転移 / エクソソーム / 細胞外小胞 / 破骨細胞 / miRNA / 蛍光イメージング / 肺転移 / 骨髄由来マクロファージ / イメージング / 肉腫 / 骨軟部腫瘍 / 微小環境 / 治療標的 Less

Investigation of microenvironment and novel therapeutic targets in bone and soft tissue tumors
- Principal Investigator
  
  土屋弘行
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kanazawa University
軟部肉腫に対する患者由来腫瘍同所移植マウスモデルを用いた個別化医療の開発Principal Investigator
- Principal Investigator
  
  五十嵐健太郎
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kanazawa University
Investigation for mechanism of metastasis using molecular imaging
- Principal Investigator
  
  Tuchiya Hiroyuki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kanazawa University
A novel bone targeting platinum complex effectively targets a cisplatinum-resistant osteosaroma in a patient-derived orthotopic xenograft (PDOX)Principal Investigator
- Principal Investigator
  
  Igarashi Kentaro
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kanazawa University

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Monostotic Fibrous Dysplasia in the Femur Strongly Expressing RANKL With Concomitant Osteoporotic Vertebral Compression Fracture: A Case Report2022
- Author(s)
  AZURIN EDELYN S.、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、MIWA SHINJI、IGARASHI KENTARO、HIGUCHI TAKASHI、YONEZAWA HIROTAKA、MORINAGA SEI、ASANO YOHEI、SAITO SHIRO、TSUCHIYA HIROYUKI
- Journal Title
  
  Cancer Diagnosis & Prognosis
  
  Volume: 2 Pages: 93-100
- DOI
  10.21873/cdp.10082
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198, KAKENHI-PROJECT-21K09317
[Journal Article] The Therapeutic Effect and Clinical Outcome of Immune Checkpoint Inhibitors on Bone Metastasis in Advanced Non-Small-Cell Lung Cancer2022
- Author(s)
  Asano Yohei、Yamamoto Norio、Demura Satoru、Hayashi Katsuhiro、Takeuchi Akihiko、Kato Satoshi、Miwa Shinji、Igarashi Kentaro、Higuchi Takashi、Yonezawa Hirotaka、Araki Yoshihiro、Morinaga Sei、Saito Shiro、Sone Takashi、Kasahara Kazuo、Tsuchiya Hiroyuki
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 12 Pages: 871675-871675
- DOI
  10.3389/fonc.2022.871675
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198
[Journal Article] Pretreatment Neutrophil Count and Platelet-lymphocyte Ratio as Predictors of Metastasis in Patients With Osteosarcoma2022
- Author(s)
  ARAKI YOSHIHIRO、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、MIWA SHINJI、IGARASHI KENTARO、HIGUCHI TAKASHI、ABE KENSAKU、TANIGUCHI YUTA、YONEZAWA HIROTAKA、MORINAGA SEI、ASANO YOHEI、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Pages: 1081-1089
- DOI
  10.21873/anticanres.15570
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198, KAKENHI-PROJECT-21K09317
[Journal Article] Therapeutic Targets and Emerging Treatments in Advanced Chondrosarcoma2022
- Author(s)
  Miwa Shinji、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Igarashi Kentaro、Tsuchiya Hiroyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 23 Pages: 1096-1096
- DOI
  10.3390/ijms23031096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198, KAKENHI-PROJECT-21K09317
[Journal Article] Osteosarcoma-derived small extracellular vesicles enhance tumor metastasis and suppress osteoclastogenesis by miR-146a-5p.2021
- Author(s)
  Yoshihiro Araki, Hisaki Aiba, Takeshi Yoshida, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Tuan D. Nguyen, Kiyo-aki Ishii, Takayuki Nojima, Satoru Takahashi, Hideki Murakami, Hiroyuki Tsuchiya and Rikinari Hanayama
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 11 Pages: 667109-667109
- DOI
  10.3389/fonc.2021.667109
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K18529, KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-19H03433, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19K07486, KAKENHI-PROJECT-21K07173, KAKENHI-PROJECT-21K08573, KAKENHI-PROJECT-21K09198, KAKENHI-PROJECT-21K09317
[Journal Article] Impact of Tumor Growth Speed of Primary Lesions on the Clinical Outcomes of Appendicular Skeletal Metastases2021
- Author(s)
  ASANO YOHEI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、MIWA SHINJI、IGARASHI KENTARO、YONEZAWA HIROTAKA、ARAKI YOSHIHIRO、MORINAGA SEI、SAITO SHIRO、NOJIMA TAKAYUKI、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Pages: 229-236
- DOI
  10.21873/anticanres.15477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198, KAKENHI-PROJECT-21K09317
[Journal Article] Clinical outcomes of frozen autograft reconstruction for the treatment of primary bone sarcoma in adolescents and young adults2021
- Author(s)
  Araki Yoshihiro、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Miwa Shinji、Igarashi Kentaro、Higuchi Takashi、Abe Kensaku、Taniguchi Yuta、Yonezawa Hirotaka、Morinaga Sei、Asano Yohei、Tsuchiya Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Pages: 17291-17291
- DOI
  10.1038/s41598-021-96162-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198
[Journal Article] The number of osteoclasts in a biopsy specimen can predict the efficacy of neoadjuvant chemotherapy for primary osteosarcoma2021
- Author(s)
  Araki Yoshihiro、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Miwa Shinji、Igarashi Kentaro、Higuchi Takashi、Abe Kensaku、Taniguchi Yuta、Yonezawa Hirotaka、Morinaga Sei、Asano Yohei、Ikeda Hiroko、Nojima Takayuki、Tsuchiya Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Pages: 1989-1989
- DOI
  10.1038/s41598-020-80504-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K18529, KAKENHI-PROJECT-21K09198
[Journal Article] Osteosarcoma Patient-derived Orthotopic Xenograft (PDOX) Models Used to Identify Novel and Effective Therapeutics: A Review2021
- Author(s)
  HIGUCHI TAKASHI、IGARASHI KENTARO、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、BOUVET MICHAEL、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Pages: 5865-5871
- DOI
  10.21873/anticanres.15406
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198
[Journal Article] Combination Methionine-methylation-axis Blockade: A Novel Approach to Target the Methionine Addiction of Cancer2021
- Author(s)
  HIGUCHI TAKASHI、HAN QINGHONG、SUGISAWA NORIHIKO、YAMAMOTO JUN、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、IGARASHI KENTARO、BOUVET MICHAEL、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Cancer Genomics - Proteomics
  
  Volume: 18 Pages: 113-120
- DOI
  10.21873/cgp.20246
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198
[Journal Article] Delayed Initiation of Treatment Is Associated With Metastasis of Malignant Bone Tumor2021
- Author(s)
  ARAKI YOSHIHIRO、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、MIWA SHINJI、IGARASHI KENTARO、HIGUCHI TAKASHI、ABE KENSAKU、TANIGUCHI YUTA、YONEZAWA HIROTAKA、MORINAGA SEI、ASANO YOHEI、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Pages: 2993-2999
- DOI
  10.21873/anticanres.15081
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198, KAKENHI-PROJECT-21K09317
[Journal Article] Complete Response of Bone Metastasis in Non-small Cell Lung Cancer With Pembrolizumab: Two Case Reports2021
- Author(s)
  ASANO YOHEI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、MIWA SHINJI、IGARASHI KENTARO、YONEZAWA HIROTAKA、ARAKI YOSHIHIRO、MORINAGA SEI、KASAHARA KAZUO、SONE TAKASHI、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Pages: 1693-1699
- DOI
  10.21873/anticanres.14933
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198
[Journal Article] A Radiological Scoring System for Differentiation between Enchondroma and Chondrosarcoma2021
- Author(s)
  Miwa Shinji、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Igarashi Kentaro、Tada Kaoru、Yonezawa Hirotaka、Morinaga Sei、Araki Yoshihiro、Asano Yohei、Saito Shiro、Okuda Miho、Taki Junichi、Ikeda Hiroko、Nojima Takayuki、Tsuchiya Hiroyuki
- Journal Title
  
  Cancers
  
  Volume: 13 Pages: 3558-3558
- DOI
  10.3390/cancers13143558
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198, KAKENHI-PROJECT-21K09317
[Journal Article] Multikinase-Inhibitor Screening in Drug-resistant Osteosarcoma Patient-derived Orthotopic Xenograft Mouse Models Identifies the Clinical Potential of Regorafenib2021
- Author(s)
  HIGUCHI TAKASHI、IGARASHI KENTARO、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、BOUVET MICHAEL、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Cancer Genomics Proteomics
  
  Volume: 18 Pages: 637-643
- DOI
  10.21873/cgp.20286
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198, KAKENHI-PROJECT-20K22802
[Journal Article] Clinical characteristics of patients with undergoing unplanned excisions of malignant soft tissue tumors2021
- Author(s)
  Morinaga Sei、Miwa Shinji、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Igarashi Kentaro、Tada Kaoru、Langit Mickhael B、Yonezawa Hirotaka、Araki Yoshihiro、Asano Yohei、Tsuchiya Hiroyuki
- Journal Title
  
  Journal of Orthopaedic Surgery
  
  Volume: 29 Pages: 1-12
- DOI
  10.1177/23094990211057597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-21K09198, KAKENHI-PROJECT-21K09317
[Journal Article] Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model2020
- Author(s)
  Higuchi Takashi、Han Qinghong、Miyake Kentaro、Oshiro Hiromichi、Sugisawa Norihiko、Tan Yuying、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 523 Pages: 135-139
- DOI
  10.1016/j.bbrc.2019.12.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Risk Factors for Postoperative Deep Infection After Malignant Bone Tumor Surgery of the Extremities2020
- Author(s)
  LANGIT MICKHAEL BANG、MIWA SHINJI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、IGARASHI KENTARO、TADA KAORU、HIGUCHI TAKASHI、YONEZAWA HIROTAKA、MORINAGA SEI、ARAKI YOSHIHIRO、ASANO YOHEI、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Pages: 3551-3557
- DOI
  10.21873/anticanres.14344
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-18K09058
[Journal Article] Clinical course of grafted cartilage in osteoarticular frozen autografts for reconstruction after resection of malignant bone and soft-tissue tumor involving an epiphysis2020
- Author(s)
  Hayashi Katsuhiro、Yamamoto Norio、Takeuchi Akihiko、Miwa Shinji、Igarashi Kentaro、Higuchi Takashi、Abe Kensaku、Taniguchi Yuta、Aiba Hisaki、Araki Yoshihiro、Yonezawa Hirotaka、Morinaga Sei、Tsuchiya Hiroyuki
- Journal Title
  
  Journal of Bone Oncology
  
  Volume: 24 Pages: 100310-100310
- DOI
  10.1016/j.jbo.2020.100310
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-18K09058
[Journal Article] PPARγ Agonist Pioglitazone in Combination With Cisplatinum Arrests a Chemotherapy-resistant Osteosarcoma PDOX Model2020
- Author(s)
  Higuchi T, Yamamoto J, Sugisawa N, Tashiro Y, Nishino H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM.
- Journal Title
  
  Cancer Genomics - Proteomics
  
  Volume: 15 Pages: 35-40
- DOI
  10.21873/cgp.20165
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08658, KAKENHI-PROJECT-19K09571
[Journal Article] Recombinant Methioninase Combined With Tumor-targeting Salmonella typhimurium A1-R Induced Regression in a PDOX Mouse Model of Doxorubicin-resistant Dedifferentiated Liposarcoma2020
- Author(s)
  IGARASHI KENTARO、KAWAGUCHI KEI、ZHAO MING、HAN QINGHONG、TAN YUYING、KIYUNA TASUKU、MIYAKE KENTARO、HIGUCHI TAKASHI、NELSON SCOTT D.、DRY SARAH M.、LI YUNFENG、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Pages: 2515-2523
- DOI
  10.21873/anticanres.14222
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Glycogen synthase kinase 3beta as a potential therapeutic target in synovial sarcoma and fibrosarcoma2020
- Author(s)
  Abe Kensaku、Yamamoto Norio、Domoto Takahiro、Bolidong Dilireba、Hayashi Katsuhiro、Takeuchi Akihiko、Miwa Shinji、Igarashi Kentaro、Inatani Hiroyuki、Aoki Yu、Higuchi Takashi、Taniguchi Yuta、Yonezawa Hirotaka、Araki Yoshihiro、Aiba Hisaki、Minamoto Toshinari、Tsuchiya Hiroyuki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Pages: 429-440
- DOI
  10.1111/cas.14271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K07710, KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-16K10850, KAKENHI-PROJECT-18K19577, KAKENHI-PROJECT-19H03727
[Journal Article] Delayed Initiation of Treatment Is Associated With Metastasis of Soft-tissue Sarcoma2020
- Author(s)
  ARAKI YOSHIHIRO、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、MIWA SHINJI、IGARASHI KENTARO、TAKASHI HIGUCHI、KENSAKU ABE、TANIGUCHI YUTA、YONEZAWA HIROTAKA、MORINAGA SEI、ASANO YOHEI、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Pages: 7009-7015
- DOI
  10.21873/anticanres.14726
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-18K09058
[Journal Article] A Novel Anionic-phosphate-platinum Complex Effectively Targets a Cisplatinum-resistant Osteosarcoma in a Patient-derived Orthotopic Xenograft Mouse Model2020
- Author(s)
  IGARASHI KENTARO、KAWAGUCHI KEI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、HIGUCHI TAKASHI、TANIGUCHI YUTA、YONEZAWA HIROTAKA、ARAKI YOSHIHIRO、MORINAGA SEI、MISRA SWETA、NELSON SCOTT D.、DRY SARAH M.、LI YUNFENG、ODANI AKIRA、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Cancer Genomics - Proteomics
  
  Volume: 17 Pages: 217-223
- DOI
  10.21873/cgp.20182
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Eribulin Regresses a Doxorubicin-resistant Dedifferentiated Liposarcoma in a Patient-derived Orthotopic Xenograft Mouse Model2020
- Author(s)
  IGARASHI KENTARO、KAWAGUCHI KEI、KIYUNA TASUKU、MIYAKE KENTARO、HIGUCHI TAKASHI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Cancer Genomics - Proteomics
  
  Volume: 17 Pages: 351-358
- DOI
  10.21873/cgp.20194
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Structural Origin and Surgical Complications of Peripheral Schwannomas2020
- Author(s)
  YONEZAWA HIROTAKA、MIWA SHINJI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、IGARASHI KENTARO、TADA KAORU、LANGIT MICKHAEL B.、HIGUCHI TAKASHI、ABE KENSAKU、TANIGUCHI YUTA、MORINAGA SEI、ARAKI YOSHIHIRO、ASANO YOHEI、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Pages: 6563-6570
- DOI
  10.21873/anticanres.14681
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-18K09058
[Journal Article] Pedicle frozen autograft?prosthesis composite reconstructions for malignant bone tumors of the proximal femur2020
- Author(s)
  Xu Gang、Miwa Shinji、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Igarashi Kentaro、Higuchi Takashi、Taniguchi Yuta、Araki Yoshihiro、Yonezawa Hirotaka、Morinaga Sei、Tsuchiya Hiroyuki
- Journal Title
  
  BMC Musculoskeletal Disorders
  
  Volume: 21 Pages: 81-81
- DOI
  10.1186/s12891-020-3112-0
- NAID
  40017372723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Recent Advances and Challenges in the Treatment of Rhabdomyosarcoma2020
- Author(s)
  Miwa Shinji、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Igarashi Kentaro、Tsuchiya Hiroyuki
- Journal Title
  
  Cancers
  
  Volume: 12 Pages: 1758-1758
- DOI
  10.3390/cancers12071758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-18K09058
[Journal Article] Diagnostic accuracies of intraoperative frozen section and permanent section examinations for histological grades during open biopsy of bone tumors2020
- Author(s)
  Miwa Shinji、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Igarashi Kentaro、Tada Kaoru、Higuchi Takashi、Yonezawa Hirotaka、Morinaga Sei、Araki Yoshihiro、Asano Yohei、Ikeda Hiroko、Nojima Takayuki、Tsuchiya Hiroyuki
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 26 Pages: 613-619
- DOI
  10.1007/s10147-020-01836-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-18K09058
[Journal Article] Intraoperative ultrasonography‐guided surgery for malignant soft tissue tumor2020
- Author(s)
  Takeuchi Akihiko、Yamamoto Norio、Hayashi Katsuhiro、Miwa Shinji、Igarashi Kentaro、Yonezawa Hirotaka、Morinaga Sei、Araki Yoshihiro、Asano Yohei、Ikeda Hiroko、Tsuchiya Hiroyuki
- Journal Title
  
  Journal of Surgical Oncology
  
  Volume: 122 Pages: 1791-1801
- DOI
  10.1002/jso.26181
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-18K09058
[Journal Article] Accuracy of histological grades from intraoperative frozen-section diagnoses of soft-tissue tumors2020
- Author(s)
  Miwa Shinji、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Igarashi Kentaro、Tada Kaoru、Higuchi Takashi、Yonezawa Hirotaka、Morinaga Sei、Araki Yoshihiro、Asano Yohei、Ikeda Hiroko、Nojima Takayuki、Tsuchiya Hiroyuki
- Journal Title
  
  International Journal of Clinical Oncology
  
  Volume: 25 Pages: 2158-2165
- DOI
  10.1007/s10147-020-01762-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-18K09058
[Journal Article] Patient-derived orthotopic xenograft models of sarcoma2020
- Author(s)
  Igarashi Kentaro、Kawaguchi Kei、Murakami Takashi、Miyake Kentaro、Kiyuna Tasuku、Miyake Masuyo、Hiroshima Yukihiko、Higuchi Takashi、Oshiro Hiromichi、Nelson Scott D.、Dry Sarah M.、Li Yunfeng、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Cancer Letters
  
  Volume: 469 Pages: 332-339
- DOI
  10.1016/j.canlet.2019.10.028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model2020
- Author(s)
  Igarashi Kentaro、Kawaguchi Kei、Zhao Ming、Kiyuna Tasuku、Miyake Kentaro、Miyake Masuyo、Nelson Scott D.、Dry Sarah M.、Li Yunfeng、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Higuchi Takashi、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Translational Oncology
  
  Volume: 13 Pages: 393-400
- DOI
  10.1016/j.tranon.2019.10.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Osimertinib regressed an EGFR-mutant lung-adenocarcinoma bone-metastasis mouse model and increased long-term survival2020
- Author(s)
  Higuchi Takashi、Sugisawa Norihiko、Park Jun Ho、Sun Yu、Zhu Guangwei、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Translational Oncology
  
  Volume: 13 Pages: 100826-100826
- DOI
  10.1016/j.tranon.2020.100826
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Satisfaction After Joint-preservation Surgery in Patients With Musculoskeletal Knee Sarcoma Based on Various Scores2019
- Author(s)
  ABE KENSAKU、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、KATO SATOSHI、MIWA SHINJI、IGARASHI KENTARO、INATANI HIROYUKI、AOKI YU、HIGUCHI TAKASHI、TANIGUCHI YUTA、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 1959-1964
- DOI
  10.21873/anticanres.13306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K09571
[Journal Article] Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice2019
- Author(s)
  Higuchi Takashi、Oshiro Hiromichi、Zhang Zhiying、Miyake Kentaro、Sugisawa Norihiko、Katsuya Yuki、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Zhao Ming、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M
- Journal Title
  
  Translational Oncology
  
  Volume: 12 Pages: 640-645
- DOI
  10.1016/j.tranon.2019.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Determining Patient Satisfaction and Treatment Desires in Patients With Musculoskeletal Sarcoma of the Knee After Joint-preservation Surgery Using a Questionnaire Survey2019
- Author(s)
  ABE KENSAKU、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、KATO SATOSHI、MIWA SHINJI、IGARASHI KENTARO、INATANI HIROYUKI、AOKI YU、HIGUCHI TAKASHI、TANIGUCHI YUTA、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 1965-1969
- DOI
  10.21873/anticanres.13307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K09571
[Journal Article] Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma2019
- Author(s)
  HIGUCHI TAKASHI、OSHIRO HIROMICHI、MIYAKE KENTARO、SUGISAWA NORIHIKO、HAN QINGHONG、TAN YUYING、PARK JUNHO、ZHANG ZHIYING、RAZMJOOEI SAHAR、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、IGARASHI KENTARO、BOUVET MICHAEL、CHAWLA SANT P.、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 4653-4657
- DOI
  10.21873/anticanres.13646
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Pioglitazone, an agonist of PPARγ, reverses doxorubicin-resistance in an osteosarcoma patient-derived orthotopic xenograft model by downregulating P-glycoprotein expression2019
- Author(s)
  Higuchi Takashi、Sugisawa Norihiko、Miyake Kentaro、Oshiro Hiromichi、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Kline Zoey、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 118 Pages: 109356-109356
- DOI
  10.1016/j.biopha.2019.109356
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Anti-tumor Effects of Cyclolinopeptide on Giant-cell Tumor of the Bone2019
- Author(s)
  TANIGUCHI YUTA、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、MIWA SHINJI、IGARASHI KENTARO、HIGUCHI TAKASHI、ABE KENSAKU、YONEZAWA HIROTAKA、ARAKI YOSHIHIRO、MORINAGA SEI、KAMEI JUNZO、NUGROHO ALFARIUS EKO、KANEDA TOSHIO、MORITA HIROSHI、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 6145-6153
- DOI
  10.21873/anticanres.13822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K09571
[Journal Article] Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model2019
- Author(s)
  Higuchi Takashi、Miyake Kentaro、Sugisawa Norihiko、Oshiro Hiromichi、Zhang Zhiying、Razmjooei Sahar、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Cancer Letters
  
  Volume: 451 Pages: 122-127
- DOI
  10.1016/j.canlet.2019.03.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model2019
- Author(s)
  Higuchi Takashi、Sugisawa Norihiko、Miyake Kentaro、Oshiro Hiromichi、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Translational Oncology
  
  Volume: 12 Pages: 1257-1263
- DOI
  10.1016/j.tranon.2019.06.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model2019
- Author(s)
  Higuchi Takashi、Miyake Kentaro、Oshiro Hiromichi、Sugisawa Norihiko、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Chawla Sant P.、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 513 Pages: 326-331
- DOI
  10.1016/j.bbrc.2019.03.191
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model2019
- Author(s)
  HIGUCHI TAKASHI、SUGISAWA NORIHIKO、MIYAKE KENTARO、OSHIRO HIROMICHI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、IGARASHI KENTARO、KLINE ZOEY、BELT PAIGE、CHAWLA SANT P.、BOUVET MICHAEL、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 4781-4786
- DOI
  10.21873/anticanres.13662
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Abdominal trunk muscle weakness and its association with chronic low back pain and risk of falling in older women2019
- Author(s)
  Kato Satoshi、Murakami Hideki、Demura Satoru、Yoshioka Katsuhito、Shinmura Kazuya、Yokogawa Noriaki、Igarashi Takashi、Yonezawa Noritaka、Shimizu Takaki、Tsuchiya Hiroyuki
- Journal Title
  
  BMC Musculoskeletal Disorders
  
  Volume: 20 Pages: 273-273
- DOI
  10.1186/s12891-019-2655-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Sorafenib and Palbociclib Combination Regresses a Cisplatinum-resistant Osteosarcoma in a PDOX Mouse Model2019
- Author(s)
  HIGUCHI TAKASHI、SUGISAWA NORIHIKO、MIYAKE KENTARO、OSHIRO HIROMICHI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、IGARASHI KENTARO、CHAWLA SANT P.、BOUVET MICHAEL、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 4079-4084
- DOI
  10.21873/anticanres.13565
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model2019
- Author(s)
  Igarashi Kentaro、Kawaguchi Kei、Kiyuna Tasuku、Miyake Kentaro、Miyake Masuyo、Nelson Scott D.、Russell Tara A.、Dry Sarah M.、Li Yunfeng、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Higuchi Takashi、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Tissue and Cell
  
  Volume: 58 Pages: 107-111
- DOI
  10.1016/j.tice.2019.04.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Presentation] Newly developed bone targeting platinum complex effectively targets cisplatin resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model2019
- Author(s)
  Igarashi K, Yamamoto N, Hayashi K, Kimura H, Takeuchi A, Miwa S, Higuchi T, Taniguchi Y, Yonezawa H, Araki Y, Morinaga S, Hoffman RM, Tsuchiya H
- Organizer
  20th International Society of Limb Salvage General Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21282

1. Tuchiya Hiroyuki (40227434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 46 results
2. 三輪真嗣 (40753455)

# of Collaborated Projects: 2 results

# of Collaborated Products: 45 results
3. 林克洋 (80507054)

# of Collaborated Projects: 2 results

# of Collaborated Products: 45 results
4. 山本憲男 (90332668)

# of Collaborated Projects: 2 results

# of Collaborated Products: 45 results
5. HANAYAMA Rikinari

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. ISHII Kiyoaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 荒木麗博

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. 高橋智

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 吉田孟史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 武内章彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 24 results
11. 山本靖彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 22 results
12. 田代良彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 堂本貴寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 源利成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Igarashi Kentaro 五十嵐 健太郎

Research Projects

Research Products

Co-Researchers

Investigation of microenvironment and novel therapeutic targets in bone and soft tissue tumors

Principal Investigator

Project Period (FY)

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Research Institution

軟部肉腫に対する患者由来腫瘍同所移植マウスモデルを用いた個別化医療の開発Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Investigation for mechanism of metastasis using molecular imaging

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel bone targeting platinum complex effectively targets a cisplatinum-resistant osteosaroma in a patient-derived orthotopic xenograft (PDOX)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Monostotic Fibrous Dysplasia in the Femur Strongly Expressing RANKL With Concomitant Osteoporotic Vertebral Compression Fracture: A Case Report2022

Author(s)

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[Journal Article] The Therapeutic Effect and Clinical Outcome of Immune Checkpoint Inhibitors on Bone Metastasis in Advanced Non-Small-Cell Lung Cancer2022

Author(s)

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DOI

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[Journal Article] Pretreatment Neutrophil Count and Platelet-lymphocyte Ratio as Predictors of Metastasis in Patients With Osteosarcoma2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic Targets and Emerging Treatments in Advanced Chondrosarcoma2022

Author(s)

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[Journal Article] Osteosarcoma-derived small extracellular vesicles enhance tumor metastasis and suppress osteoclastogenesis by miR-146a-5p.2021

Author(s)

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[Journal Article] Impact of Tumor Growth Speed of Primary Lesions on the Clinical Outcomes of Appendicular Skeletal Metastases2021

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[Journal Article] Clinical outcomes of frozen autograft reconstruction for the treatment of primary bone sarcoma in adolescents and young adults2021

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[Journal Article] The number of osteoclasts in a biopsy specimen can predict the efficacy of neoadjuvant chemotherapy for primary osteosarcoma2021

Author(s)

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Data Source

[Journal Article] Osteosarcoma Patient-derived Orthotopic Xenograft (PDOX) Models Used to Identify Novel and Effective Therapeutics: A Review2021

Author(s)

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[Journal Article] Combination Methionine-methylation-axis Blockade: A Novel Approach to Target the Methionine Addiction of Cancer2021

Author(s)

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Data Source

[Journal Article] Delayed Initiation of Treatment Is Associated With Metastasis of Malignant Bone Tumor2021

Author(s)

Igarashi Kentaro 五十嵐健太郎