Igarashi Kentaro 五十嵐健太郎

Researcher Number	80622860
Other IDs
Affiliation (Current)	2020: 金沢大学, 医薬保健学総合研究科, 特任助教
Affiliation (based on the past Project Information) *help	2018 – 2020: 金沢大学, 医薬保健学総合研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / 0901:Oncology and related fields Except Principal Investigator Basic Section 56020:Orthopedics-related
Keywords	Principal Investigator 患者由来腫瘍同所移植モデル / 軟部肉腫 / 個別化医療 / 骨肉腫 / シスプラチン耐性 / 高骨移行性 / 新規プラチナ製剤 / シスプラチン治療抵抗性 / 高骨親和性 / 患者由来腫瘍同所移植 / 薬剤耐性 / 骨親和性 … More Except Principal Investigator … More

軟部肉腫に対する患者由来腫瘍同所移植マウスモデルを用いた個別化医療の開発Principal InvestigatorOngoing
- Principal Investigator
  
  五十嵐健太郎
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kanazawa University
Investigation for mechanism of metastasis using molecular imagingOngoing
- Principal Investigator
  
  土屋弘行
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kanazawa University
A novel bone targeting platinum complex effectively targets a cisplatinum-resistant osteosaroma in a patient-derived orthotopic xenograft (PDOX)Principal Investigator
- Principal Investigator
  
  Igarashi Kentaro
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0901:Oncology and related fields
- Research Institution
  Kanazawa University

All 2020 2019

All Journal Article Presentation

[Journal Article] Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model2020
- Author(s)
  Igarashi Kentaro、Kawaguchi Kei、Zhao Ming、Kiyuna Tasuku、Miyake Kentaro、Miyake Masuyo、Nelson Scott D.、Dry Sarah M.、Li Yunfeng、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Higuchi Takashi、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Translational Oncology
  
  Volume: 13 Pages: 393-400
- DOI
  10.1016/j.tranon.2019.10.005
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Glycogen synthase kinase 3beta as a potential therapeutic target in synovial sarcoma and fibrosarcoma2020
- Author(s)
  Abe Kensaku、Yamamoto Norio、Domoto Takahiro、Bolidong Dilireba、Hayashi Katsuhiro、Takeuchi Akihiko、Miwa Shinji、Igarashi Kentaro、Inatani Hiroyuki、Aoki Yu、Higuchi Takashi、Taniguchi Yuta、Yonezawa Hirotaka、Araki Yoshihiro、Aiba Hisaki、Minamoto Toshinari、Tsuchiya Hiroyuki
- Journal Title
  
  Cancer Science
  
  Volume: 111 Pages: 429-440
- DOI
  10.1111/cas.14271
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K07710, KAKENHI-PROJECT-19K09571, KAKENHI-PROJECT-19H03727, KAKENHI-PROJECT-16K10850
[Journal Article] PPARγ Agonist Pioglitazone in Combination With Cisplatinum Arrests a Chemotherapy-resistant Osteosarcoma PDOX Model2020
- Author(s)
  Higuchi T, Yamamoto J, Sugisawa N, Tashiro Y, Nishino H, Yamamoto N, Hayashi K, Kimura H, Miwa S, Igarashi K, Bouvet M, Singh SR, Tsuchiya H, Hoffman RM.
- Journal Title
  
  Cancer Genomics - Proteomics
  
  Volume: 15 Pages: 35-40
- DOI
  10.21873/cgp.20165
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08658, KAKENHI-PROJECT-19K09571
[Journal Article] Patient-derived orthotopic xenograft models of sarcoma2020
- Author(s)
  Igarashi Kentaro、Kawaguchi Kei、Murakami Takashi、Miyake Kentaro、Kiyuna Tasuku、Miyake Masuyo、Hiroshima Yukihiko、Higuchi Takashi、Oshiro Hiromichi、Nelson Scott D.、Dry Sarah M.、Li Yunfeng、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Cancer Letters
  
  Volume: 469 Pages: 332-339
- DOI
  10.1016/j.canlet.2019.10.028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Pedicle frozen autograft?prosthesis composite reconstructions for malignant bone tumors of the proximal femur2020
- Author(s)
  Xu Gang、Miwa Shinji、Yamamoto Norio、Hayashi Katsuhiro、Takeuchi Akihiko、Igarashi Kentaro、Higuchi Takashi、Taniguchi Yuta、Araki Yoshihiro、Yonezawa Hirotaka、Morinaga Sei、Tsuchiya Hiroyuki
- Journal Title
  
  BMC Musculoskeletal Disorders
  
  Volume: 21 Pages: 81-81
- DOI
  10.1186/s12891-020-3112-0
- NAID
  40017372723
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model2020
- Author(s)
  Higuchi Takashi、Han Qinghong、Miyake Kentaro、Oshiro Hiromichi、Sugisawa Norihiko、Tan Yuying、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 523 Pages: 135-139
- DOI
  10.1016/j.bbrc.2019.12.024
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model2019
- Author(s)
  Igarashi Kentaro、Kawaguchi Kei、Kiyuna Tasuku、Miyake Kentaro、Miyake Masuyo、Nelson Scott D.、Russell Tara A.、Dry Sarah M.、Li Yunfeng、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Higuchi Takashi、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Tissue and Cell
  
  Volume: 58 Pages: 107-111
- DOI
  10.1016/j.tice.2019.04.010
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Satisfaction After Joint-preservation Surgery in Patients With Musculoskeletal Knee Sarcoma Based on Various Scores2019
- Author(s)
  ABE KENSAKU、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、KATO SATOSHI、MIWA SHINJI、IGARASHI KENTARO、INATANI HIROYUKI、AOKI YU、HIGUCHI TAKASHI、TANIGUCHI YUTA、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 1959-1964
- DOI
  10.21873/anticanres.13306
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K09571
[Journal Article] Anti-tumor Effects of Cyclolinopeptide on Giant-cell Tumor of the Bone2019
- Author(s)
  TANIGUCHI YUTA、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、MIWA SHINJI、IGARASHI KENTARO、HIGUCHI TAKASHI、ABE KENSAKU、YONEZAWA HIROTAKA、ARAKI YOSHIHIRO、MORINAGA SEI、KAMEI JUNZO、NUGROHO ALFARIUS EKO、KANEDA TOSHIO、MORITA HIROSHI、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 6145-6153
- DOI
  10.21873/anticanres.13822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K09571
[Journal Article] Determining Patient Satisfaction and Treatment Desires in Patients With Musculoskeletal Sarcoma of the Knee After Joint-preservation Surgery Using a Questionnaire Survey2019
- Author(s)
  ABE KENSAKU、YAMAMOTO NORIO、HAYASHI KATSUHIRO、TAKEUCHI AKIHIKO、KATO SATOSHI、MIWA SHINJI、IGARASHI KENTARO、INATANI HIROYUKI、AOKI YU、HIGUCHI TAKASHI、TANIGUCHI YUTA、TSUCHIYA HIROYUKI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 1965-1969
- DOI
  10.21873/anticanres.13307
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09058, KAKENHI-PROJECT-19K09571
[Journal Article] Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma2019
- Author(s)
  HIGUCHI TAKASHI、OSHIRO HIROMICHI、MIYAKE KENTARO、SUGISAWA NORIHIKO、HAN QINGHONG、TAN YUYING、PARK JUNHO、ZHANG ZHIYING、RAZMJOOEI SAHAR、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、IGARASHI KENTARO、BOUVET MICHAEL、CHAWLA SANT P.、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 4653-4657
- DOI
  10.21873/anticanres.13646
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Abdominal trunk muscle weakness and its association with chronic low back pain and risk of falling in older women2019
- Author(s)
  Kato Satoshi、Murakami Hideki、Demura Satoru、Yoshioka Katsuhito、Shinmura Kazuya、Yokogawa Noriaki、Igarashi Takashi、Yonezawa Noritaka、Shimizu Takaki、Tsuchiya Hiroyuki
- Journal Title
  
  BMC Musculoskeletal Disorders
  
  Volume: 20 Pages: 273-273
- DOI
  10.1186/s12891-019-2655-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] The Combination of Olaratumab with Doxorubicin and Cisplatinum Regresses a Chemotherapy-Resistant Osteosarcoma in a Patient-Derived Orthotopic Xenograft Mouse Model2019
- Author(s)
  Higuchi Takashi、Sugisawa Norihiko、Miyake Kentaro、Oshiro Hiromichi、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Translational Oncology
  
  Volume: 12 Pages: 1257-1263
- DOI
  10.1016/j.tranon.2019.06.002
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Pioglitazone, an agonist of PPARγ, reverses doxorubicin-resistance in an osteosarcoma patient-derived orthotopic xenograft model by downregulating P-glycoprotein expression2019
- Author(s)
  Higuchi Takashi、Sugisawa Norihiko、Miyake Kentaro、Oshiro Hiromichi、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Kline Zoey、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 118 Pages: 109356-109356
- DOI
  10.1016/j.biopha.2019.109356
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Olaratumab combined with doxorubicin and ifosfamide overcomes individual doxorubicin and olaratumab resistance of an undifferentiated soft-tissue sarcoma in a PDOX mouse model2019
- Author(s)
  Higuchi Takashi、Miyake Kentaro、Sugisawa Norihiko、Oshiro Hiromichi、Zhang Zhiying、Razmjooei Sahar、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Cancer Letters
  
  Volume: 451 Pages: 122-127
- DOI
  10.1016/j.canlet.2019.03.003
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Osimertinib Regresses an EGFR-Mutant Cisplatinum- Resistant Lung Adenocarcinoma Growing in the Brain in Nude Mice2019
- Author(s)
  Higuchi Takashi、Oshiro Hiromichi、Zhang Zhiying、Miyake Kentaro、Sugisawa Norihiko、Katsuya Yuki、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Zhao Ming、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M
- Journal Title
  
  Translational Oncology
  
  Volume: 12 Pages: 640-645
- DOI
  10.1016/j.tranon.2019.01.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Combination Treatment With Sorafenib and Everolimus Regresses a Doxorubicin-resistant Osteosarcoma in a PDOX Mouse Model2019
- Author(s)
  HIGUCHI TAKASHI、SUGISAWA NORIHIKO、MIYAKE KENTARO、OSHIRO HIROMICHI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、IGARASHI KENTARO、KLINE ZOEY、BELT PAIGE、CHAWLA SANT P.、BOUVET MICHAEL、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 4781-4786
- DOI
  10.21873/anticanres.13662
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Sorafenib and Palbociclib Combination Regresses a Cisplatinum-resistant Osteosarcoma in a PDOX Mouse Model2019
- Author(s)
  HIGUCHI TAKASHI、SUGISAWA NORIHIKO、MIYAKE KENTARO、OSHIRO HIROMICHI、YAMAMOTO NORIO、HAYASHI KATSUHIRO、KIMURA HIROAKI、MIWA SHINJI、IGARASHI KENTARO、CHAWLA SANT P.、BOUVET MICHAEL、SINGH SHREE RAM、TSUCHIYA HIROYUKI、HOFFMAN ROBERT M.
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Pages: 4079-4084
- DOI
  10.21873/anticanres.13565
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Journal Article] Trabectedin and irinotecan combination regresses a cisplatinum-resistant osteosarcoma in a patient-derived orthotopic xenograft nude-mouse model2019
- Author(s)
  Higuchi Takashi、Miyake Kentaro、Oshiro Hiromichi、Sugisawa Norihiko、Yamamoto Norio、Hayashi Katsuhiro、Kimura Hiroaki、Miwa Shinji、Igarashi Kentaro、Chawla Sant P.、Bouvet Michael、Singh Shree Ram、Tsuchiya Hiroyuki、Hoffman Robert M.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 513 Pages: 326-331
- DOI
  10.1016/j.bbrc.2019.03.191
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09571
[Presentation] Newly developed bone targeting platinum complex effectively targets cisplatin resistant relapsed osteosarcoma in a patient-derived orthotopic xenograft (PDOX) mouse model2019
- Author(s)
  Igarashi K, Yamamoto N, Hayashi K, Kimura H, Takeuchi A, Miwa S, Higuchi T, Taniguchi Y, Yonezawa H, Araki Y, Morinaga S, Hoffman RM, Tsuchiya H
- Organizer
  20th International Society of Limb Salvage General Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21282

1. 土屋弘行 (40227434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
2. 三輪真嗣 (40753455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
3. 林克洋 (80507054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
4. 山本憲男 (90332668)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
5. 山本靖彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
6. 武内章彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 堂本貴寛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 源利成

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 田代良彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Igarashi Kentaro 五十嵐 健太郎

Research Projects

Research Products

Co-Researchers

軟部肉腫に対する患者由来腫瘍同所移植マウスモデルを用いた個別化医療の開発Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation for mechanism of metastasis using molecular imagingOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A novel bone targeting platinum complex effectively targets a cisplatinum-resistant osteosaroma in a patient-derived orthotopic xenograft (PDOX)Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Exquisite Tumor Targeting by Salmonella A1-R in Combination with Caffeine and Valproic Acid Regresses an Adult Pleomorphic Rhabdomyosarcoma Patient-Derived Orthotopic Xenograft Mouse Model2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glycogen synthase kinase 3beta as a potential therapeutic target in synovial sarcoma and fibrosarcoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PPARγ Agonist Pioglitazone in Combination With Cisplatinum Arrests a Chemotherapy-resistant Osteosarcoma PDOX Model2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Patient-derived orthotopic xenograft models of sarcoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pedicle frozen autograft?prosthesis composite reconstructions for malignant bone tumors of the proximal femur2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Combination of oral recombinant methioninase and decitabine arrests a chemotherapy-resistant undifferentiated soft-tissue sarcoma patient-derived orthotopic xenograft mouse model2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Satisfaction After Joint-preservation Surgery in Patients With Musculoskeletal Knee Sarcoma Based on Various Scores2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anti-tumor Effects of Cyclolinopeptide on Giant-cell Tumor of the Bone2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Determining Patient Satisfaction and Treatment Desires in Patients With Musculoskeletal Sarcoma of the Knee After Joint-preservation Surgery Using a Questionnaire Survey2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral Recombinant Methioninase, Combined With Oral Caffeine and Injected Cisplatinum, Overcome Cisplatinum-Resistance and Regresses Patient-derived Orthotopic Xenograft Model of Osteosarcoma2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Abdominal trunk muscle weakness and its association with chronic low back pain and risk of falling in older women2019

Author(s)

Igarashi Kentaro 五十嵐健太郎