Hata Hiroki 秦広樹

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HATA HIROKI 秦広樹

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Researcher Number	80638198
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 教授
Affiliation (based on the past Project Information) *help	2018 – 2022: 大阪大学, 医学系研究科, 特任准教授(常勤) 2018: 大阪大学, 医学系研究科, 助教 2017: 大阪大学, 医学系研究科, 講師 2016: 大阪大学, 医学(系)研究科(研究院), 助教 2016: 大阪大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator General surgery Except Principal Investigator Cardiovascular surgery / Basic Section 55030:Cardiovascular surgery-related / Basic Section 55010:General surgery and pediatric surgery-related
Keywords	Principal Investigator 補助人工心臓 / 心移植 / 心臓外科 / 人工臓器 / 三尖弁閉鎖不全症 / 大動脈弁閉鎖不全症 / 僧帽弁閉鎖不全症 / 三尖弁閉鎖不全 / 大動脈弁閉鎖不全 / 僧帽弁閉鎖不全 / 左心補助人工心臓 … More Except Principal Investigator … More 再生医療 / iPS細胞 / 重症心不全 / 補助人工心臓 / 心不全 / プロスタサイクリン作動薬 / 心筋再生 / 血管新生 / オキシム誘導体 / in vivo / 心筋細胞 / MHC適合移植 / iPS細胞由来心筋細胞 / 三次元組織化 / 免疫チェックポイント機構 / 左室unloading / 左室補助人工心臓 / 細胞極性因子 / 脳卒中 / 間葉系幹細胞 / 神経再生 / 心筋虚血再灌流 / DDS / 心筋血管新生 / 心筋虚血再灌流障害 / ナノメディシン / プロスタサイクリンアゴニスト / 心保護効果 / OXM-NP / 心筋再生効果 / 心筋虚血再灌流傷害 / ナノパーティクル / プロスタサイクリン / 細胞外基質 / 組織修復 / 細胞外マトリックス / 幹細胞ニッチ / 二光子顕微鏡 / 心臓 / イメージング / No reflow現象 / 心筋イメージング / in vivo imaging / 不均一性 / 虚血再灌流障害 / 心筋虚血 / in vivo イメージング / 微小循環障害の改善 / 局所心筋血流量の改善 / 局所心機能の改善 / 心筋血管抵抗 / 心筋血流量 / 有茎大網 / 免疫学的拒絶反応 / 移植後拒絶反応 / 心不全治療 / ｵｷｼﾑ誘導体 / 難治性潰瘍剤 / 徐放性製剤 / 難治性創傷治癒促進剤 / YS-1402 / ONO-1301 / 創傷治癒促進剤 / 体内再生因子誘導剤 / 創傷治癒促進 / 血管新生促進剤 / 細胞外基質リモデリング / 毛細血管網 / ３次元心筋組織 / 心機能回復 / iPS由来三次元心筋組織 / 細胞保存 / 凍結 / 骨格筋芽細胞 / ガラス化凍結 / 細胞シート / アロジェネイック / MHC / 免疫拒絶 / 免疫抑制剤 / 自然免疫 / MSC併用移植 / 免疫寛容 / 他家移植 / 疾患得的iPS細胞 / 創薬 / 三次元心筋組織 / 薬剤スクリーニングシステム / 心臓線維化モデル / 心毒性評価 / 三次元組織 / iPS由来心筋細胞 / 創薬スクリーニング Less

Functional Recovery of Failing Heart by Mechanical Unloading associated with c-Myc Expression via aPKC-FoXOs Pathway
- Principal Investigator
  
  Kawamura Takuji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Osaka University
Regulation of Heart Failure Pathophysiology by Immune Checkpoint Mechanisms
- Principal Investigator
  
  Kawamura Ai
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Osaka University
補助人工心臓装着後の脳血管合併症に対する神経再生治療の開発
- Principal Investigator
  
  斎藤俊輔
- Project Period (FY)
  2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  International University of Health and Welfare
Analisys valve function and morphorogic change in the patients with long-support LVADPrincipal Investigator
- Principal Investigator
  
  HATA HIROKI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Intravital imaging of cardiac tissue reveals pathological dynamics in injured heart
- Principal Investigator
  
  Ryohei Matsuura
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Osaka University
Development of heart failure treatment by new device using extracellular matrix modulating cardiac stem cell niche
- Principal Investigator
  
  Sawa Yoshiki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Osaka University
OXN-NP Produce Cardioprotective Effects
- Principal Investigator
  
  FUKUSHIMA SATSUKI
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  National Cardiovascular Center Research Institute
Study of drug discovery using cardiomyocytes derived from iPS cells in cardiovascular diseases
- Principal Investigator
  
  Sawa Yoshiki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Osaka University
iPSC derived three dimensional cardiac tissue having circulatory system
- Principal Investigator
  
  Miyagawa Shigeru
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Osaka University
Evaluation of accelerating effects of an angiogenic agent on wound healing after cardiac surgery
- Principal Investigator
  
  Toda Koichi
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Osaka University
The impact of transplantation of cardiomyocyte sheet derived from MHC homozygous induced pluripotent stem cells
- Principal Investigator
  
  Saito Shunsuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Osaka University
Overcoming ischemic cardiomyopathy by angiogenic drugs
- Principal Investigator
  
  Ueno Takayoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Osaka University
Development of immune tolerance method for clinical application of allogeneic iPS cells
- Principal Investigator
  
  Miyagawa Shigeru
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Osaka University
The Development of Cryo-Vetrification Method in Human Myoblast Cell Sheet for Propagation of Regeneration Therapy
- Principal Investigator
  
  Yoshikawa Yasushi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Osaka University

All 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Prostacyclin Analog-Loaded Nanoparticles Attenuate Myocardial Ischemia/Reperfusion Injury in Rats2019
- Author(s)
  Shin Yajima, Shigeru Miyagawa, Satsuki Fukushima, Yoshiki Sakai, Hiroko Iseoka, Akima Harada, Kayako Isohashi, Genki Horitsugi, Yuki Mori, Motoko Shiozaki, Hirotatsu Okawara, Ryoto Sakaniwa, Jun Hatazawa, Yoshichika Yoshioka, Yoshiki Sawa
- Journal Title
  
  Jounal of American College of Cardiology Basic to Translational Science
  
  Volume: 印刷中
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10628
[Journal Article] Impact of mitral valve intervention with left ventricular assist device implantation on postoperative outcomes and morphologic change2018
- Author(s)
  Hata Hiroki、Fujita Tomoyuki、Ishibashi-Ueda Hatsue、Kuroda Kensuke、Seguchi Osamu、Matsumoto Yorihiko、Yanase Masanobu、Sato Takuma、Nakajima Seiko、Fukushima Norihide、Kobayashi Junjiro
- Journal Title
  
  Journal of Artificial Organs
  
  Volume: 21 Issue: 2 Pages: 164-171
- DOI
  10.1007/s10047-017-1010-5
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10446
[Journal Article] A prostacyclin agonist and an omental flap increased myocardial blood flow in a porcine chronic ischemia model.2018
- Author(s)
  Yajima , Miyagawa , Fukushima , Sakai Y, Isohashi , Watabe , Ikeda , Horitsugi G, Harada A, Sakaniwa R, Hatazawa J, Sawa Y
- Journal Title
  
  Journal of Thorac Cardiovasc Surgery
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10214
[Journal Article] Teratocarcinomas Arising from Allogeneic Induced Pluripotent Stem Cell-Derived Cardiac Tissue Constructs Provoked Host Immune Rejection in Mice.2016
- Author(s)
  Kawamura A, Miyagawa S, Fukushima S, Kawamura T, Kashiyama N, Ito E, Watabe T, Masuda S, Toda K, Hatazawa J, Morii E, Sawa Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 29 Issue: 1 Pages: 22130-22130
- DOI
  10.1038/srep19464
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293311, KAKENHI-PROJECT-15K10211
[Presentation] 補助人工心臓による重症心不全治療の最前線2019
- Author(s)
  秦　広樹、戸田宏一、宮川　繁、吉川泰司、吉岡大輔、甲斐沼尚、河村拓史、河村　愛、澤　芳樹
- Organizer
  日本循環器学会
- Data Source
  KAKENHI-PROJECT-16K10446
[Presentation] Impact of concomitant valve surgery at the time of HeartMate II left ventricular assist device implantation; Japanese multicenter study2019
- Author(s)
  Hiroki Hata, Koichi Toda, Shigeru Miyagawa, Yasushi Yoshikawa, Daisuke Yoshioka, Satoshi Kainuma, Takuji Kawamura, Ai Kawamura, Yoshiki Sawa
- Organizer
  ISHLT
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10446
[Presentation] The Goal of Destination Therapy2018
- Author(s)
  秦　広樹、戸田宏一、宮川　繁、吉川泰司、吉岡大輔、甲斐沼尚、吉田昇平、澤　芳樹
- Organizer
  日本循環器学会
- Data Source
  KAKENHI-PROJECT-16K10446
[Presentation] 植込み型LVADの長期サポートにおける合併症と再入院の現状と対策：DT導入に向けて心臓外科医ができること2018
- Author(s)
  秦　広樹、戸田宏一、宮川　繁、吉川泰司、吉岡大輔、甲斐沼尚、吉田昇平、澤　芳樹
- Organizer
  日本人工臓器学会
- Data Source
  KAKENHI-PROJECT-16K10446
[Presentation] The usefullness of peripheral ECMO as a bridge to implantable LVAD in progressive decline heart failure patients2017
- Author(s)
  Hiroki Hata
- Organizer
  44th European Society for Artificial Organs
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10446
[Presentation] 大阪大学における植込み型LVAD装着手術と管理の実際2017
- Author(s)
  秦　広樹
- Organizer
  第55回日本人工臓器学会大会
- Data Source
  KAKENHI-PROJECT-16K10446
[Presentation] Should mitral regurgitation be corrected at the time of left ventricular assist device implantation?2016
- Author(s)
  Hiroki Hata
- Organizer
  30th EACTS (European Association for Cardio-Thoracic Surgery) Annual Meeting
- Place of Presentation
  バルセロナ　スペイン
- Year and Date
  2016-10-01
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10446
[Presentation] 重症心不全に対する外科治療成績と今後の治療連略2016
- Author(s)
  秦　広樹
- Organizer
  第20回日本心不全学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-16K10446

1. FUKUSHIMA SATSUKI (80596867)

# of Collaborated Projects: 10 results

# of Collaborated Products: 3 results
2. Miyagawa Shigeru (70544237)

# of Collaborated Projects: 5 results

# of Collaborated Products: 2 results
3. Toda Koichi (40379235)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
4. Saito Shunsuke (30600126)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. Yoshikawa Yasushi (40570594)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. Sawa Yoshiki (00243220)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. Kawamura Takuji (60839398)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. Kawamura Ai (10838923)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 仲村輝也 (90511626)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 今西悠基子 (10707582)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 増田茂夫 (10396749)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. Ueno Takayoshi (60437316)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Ryohei Matsuura (10768922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 松崎典弥 (00419467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 川村匡 (70583011)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 小林順二郎 (20393233)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 藤田知之 (10457012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 福嶌教偉 (30263247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 植田初江 (40522983)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. 瀬口理 (60570869)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 松本順彦 (10781908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 堂前圭太郎 (20774219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 吉岡大輔 (40645959)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
24. 齋藤充弘 (20448038)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 寒川延子 (30432579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. SEKIGUCHI Kiyotoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Hata Hiroki 秦 広樹

HATA HIROKI 秦 広樹

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[Journal Article] Prostacyclin Analog-Loaded Nanoparticles Attenuate Myocardial Ischemia/Reperfusion Injury in Rats2019

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Hata Hiroki 秦広樹

HATA HIROKI 秦広樹