Morotomi Keiko 諸冨桂子

Researcher Number	80639435
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2018: 熊本大学, パルスパワー科学研究所, 特別研究員 2015: 熊本大学, 学内共同利用施設等, 特別研究員 2013 – 2014: 熊本大学, パルスパワー科学研究所, 研究支援推進員
Review Section/Research Field	Principal Investigator Biomedical engineering/Biomaterial science and engineering
Keywords	Principal Investigator 細胞死 / 癌治療 / トランスグルタミナーゼ / 免疫反応 / オートファジー / ナノ秒高電圧パルス / アポトーシス / スフェロイド / カルシウム / ポリADPリボース / ネクローシス / ナノ秒電気パルス

Research toward establishing a novel cancer therapy utilizing unique biological actions of nanosecond high-voltage electric pulsesPrincipal Investigator
- Principal Investigator
  
  Morotomi Keiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Kumamoto University
Study for a new cancer therapy using novel stress response evoked in tumor cells by nanosecond electric pulsesPrincipal Investigator
- Principal Investigator
  
  Morotomi Keiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Kumamoto University

All 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] Protein Phosphorylation (Editor: Claude Prigent) Section 2, Chapter 5. Phosphorylation-mediated control of stress responses induced by nanosecond pulsed electric fields. pp 97 - 114.2017
- Author(s)
  Ken-ichi Yano, Keiko Morotomi-Yano
- Total Pages
  193
- Publisher
  InTech Open
- ISBN
  9789535136262
- Data Source
  KAKENHI-PROJECT-16K01363
[Journal Article] Dynamic behavior of DNA topoisomerase IIβ in response to DNA double-strand breaks.2018
- Author(s)
  Morotomi-Yano K, Saito S, Adachi N, Yano KI.
- Journal Title
  
  Sci. Rep.
  
  Volume: 8 Issue: 1 Pages: 10344-10344
- DOI
  10.1038/s41598-018-28690-6
- NAID
  120006697280
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19407, KAKENHI-PROJECT-16K01363
[Journal Article] Calcium-dependent activation of transglutaminase 2 by nanosecond pulsed electric fields.2017
- Author(s)
  Keiko Morotomi-Yano and Ken-ichi Yano
- Journal Title
  
  FEBS Open Bio
  
  Volume: 7 Issue: 7 Pages: 934-943
- DOI
  10.1002/2211-5463.12227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K01363
[Journal Article] Extracellular calcium differentially affects intracellular responses to nanosecond pulsed electric fields.2015
- Author(s)
  Keiko Morotomi-Yano and Ken-ichi Yano
- Journal Title
  
  Biochemistry and Biotechnology Research
  
  Volume: 3 Pages: 51-60
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25350533
[Journal Article] Different involvement of extracellular calcium in two modes of cell death induced by nanosecond pulsed electric fields2014
- Author(s)
  Keiko Morotomi-Yano, Hidenori Akiyama, Ken-ichi Yano
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 555-556 Pages: 47-54
- DOI
  10.1016/j.abb.2014.05.020
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25289076, KAKENHI-PROJECT-25350533, KAKENHI-PROJECT-25630112, KAKENHI-PROJECT-26350540
[Journal Article] Nanosecond pulsed electric fields induce poly(ADP-ribose) formation and non-apoptotic cell death in HeLa S3 cells2013
- Author(s)
  K. Morotomi-Yano, H. Akiyama, K. Yano
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 438 Issue: 3 Pages: 557-562
- DOI
  10.1016/j.bbrc.2013.07.083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25289076, KAKENHI-PROJECT-25350533
[Presentation] Nanosecond pulsed electric fields induce extracellular trap formation as a neutrophil-specific immune response in human HL-60 cells2018
- Author(s)
  Tsubasa Koga, Keiko Morotomi-Yano, Takashi Sakugawa, and Ken-ichi Yano
- Organizer
  ISPlasma2018
- Data Source
  KAKENHI-PROJECT-16K01363
[Presentation] ナノ秒パルス高電界に対するヒト好中球の応答反応2018
- Author(s)
  古賀飛翔、諸冨桂子、佐久川貴志、矢野憲一
- Organizer
  放電/プラズマ・パルスパワー合同研究会
- Data Source
  KAKENHI-PROJECT-16K01363
[Presentation] Dynamic behavior of DNA topoisomerase II beta in response to DNA double-strand breaks2018
- Author(s)
  Keiko Morotomi-Yano, Shinta Saito, Noritaka Adachi, and Ken-ichi Yano
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K01363
[Presentation] ナノ秒パルス高電界によるヒト免疫細胞の活性化2017
- Author(s)
  古賀飛翔、諸冨桂子、佐久川貴志、矢野憲一
- Organizer
  プラズマ・パルスパワー・放電合同研究会、熊本大学
- Data Source
  KAKENHI-PROJECT-16K01363
[Presentation] Nanosecond Pulsed Electric Fields Induce Activation of Transglutaminase 2 that Causes Gross Protein Crosslinking2017
- Author(s)
  Ken-ichi Yano and Keiko Morotomi-Yano
- Organizer
  14rd International Conference on Flow Dynamics (ICFD2016)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01363
[Presentation] ナノ秒電気パルスはトランスグルタミナーゼ2による過剰なタンパク質架橋とネクローシスをカルシウム依存的に引き起こす2017
- Author(s)
  諸冨桂子、矢野憲一
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K01363
[Presentation] Nanosecond pulsed electric fields induce activation of transglutaminase 2 that causes gross protein crosslinking in a calcium-dependent manner.2017
- Author(s)
  Ken-ichi Yano, Keiko Morotomi-Yano
- Organizer
  2nd World congress on electroporation and pulsed electric fields in biology, medicine and food & environmental technologies.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01363
[Presentation] Stimulation of differentiated HL-60 cells by nanosecond pulsed electric fields leads to the formation of extracellular traps, an immune response of neutrophils.2017
- Author(s)
  Ken-ichi Yano, Keiko Morotomi-Yano, Tsubasa Koga.
- Organizer
  2nd World congress on electroporation and pulsed electric fields in biology, medicine and food & environmental technologies.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K01363
[Presentation] ナノ秒パルス高電界によるトランスグルタミナーゼ2のカルシウム依存的な活性化2016
- Author(s)
  矢野憲一、諸冨桂子
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-16K01363
[Presentation] ナノ秒電気パルスによって誘導されるネクローシスはカルシウム依存的な細胞内エネルギーレベルの低下とポリADPリボース形成を伴う2015
- Author(s)
  諸冨桂子、矢野憲一
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会合同大会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2015-12-02
- Data Source
  KAKENHI-PROJECT-25350533
[Presentation] ナノ秒電気パルスによって誘導される細胞死の様式はカルシウム依存的に決定される2014
- Author(s)
  諸冨桂子、矢野憲一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-26
- Data Source
  KAKENHI-PROJECT-25350533
[Presentation] ナノ秒パルス高電界によって引き起こされるポリADPリボース形成を伴う非アポトーシス性細胞死誘導の分子機構
- Author(s)
  諸冨桂子、矢野憲一
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25350533

1. AKIYAMA Hidenori (50126827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. YANO Ken-ichi (70311230)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 足立典隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Morotomi Keiko 諸冨 桂子

Research Projects

Research Products

Co-Researchers

Research toward establishing a novel cancer therapy utilizing unique biological actions of nanosecond high-voltage electric pulsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Study for a new cancer therapy using novel stress response evoked in tumor cells by nanosecond electric pulsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Protein Phosphorylation (Editor: Claude Prigent) Section 2, Chapter 5. Phosphorylation-mediated control of stress responses induced by nanosecond pulsed electric fields. pp 97 - 114.2017

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Dynamic behavior of DNA topoisomerase IIβ in response to DNA double-strand breaks.2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Calcium-dependent activation of transglutaminase 2 by nanosecond pulsed electric fields.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Extracellular calcium differentially affects intracellular responses to nanosecond pulsed electric fields.2015

Author(s)

Journal Title

Data Source

[Journal Article] Different involvement of extracellular calcium in two modes of cell death induced by nanosecond pulsed electric fields2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nanosecond pulsed electric fields induce poly(ADP-ribose) formation and non-apoptotic cell death in HeLa S3 cells2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Nanosecond pulsed electric fields induce extracellular trap formation as a neutrophil-specific immune response in human HL-60 cells2018

Author(s)

Organizer

Data Source

[Presentation] ナノ秒パルス高電界に対するヒト好中球の応答反応2018

Author(s)

Organizer

Data Source

[Presentation] Dynamic behavior of DNA topoisomerase II beta in response to DNA double-strand breaks2018

Author(s)

Organizer

Data Source

[Presentation] ナノ秒パルス高電界によるヒト免疫細胞の活性化2017

Author(s)

Organizer

Data Source

[Presentation] Nanosecond Pulsed Electric Fields Induce Activation of Transglutaminase 2 that Causes Gross Protein Crosslinking2017

Author(s)

Organizer

Data Source

[Presentation] ナノ秒電気パルスはトランスグルタミナーゼ2による過剰なタンパク質架橋とネクローシスをカルシウム依存的に引き起こす2017

Author(s)

Organizer

Data Source

[Presentation] Nanosecond pulsed electric fields induce activation of transglutaminase 2 that causes gross protein crosslinking in a calcium-dependent manner.2017

Author(s)

Organizer

Data Source

[Presentation] Stimulation of differentiated HL-60 cells by nanosecond pulsed electric fields leads to the formation of extracellular traps, an immune response of neutrophils.2017

Author(s)

Organizer

Data Source

[Presentation] ナノ秒パルス高電界によるトランスグルタミナーゼ2のカルシウム依存的な活性化2016

Morotomi Keiko 諸冨桂子