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Takada Hitomi  高田 仁実

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TAKADA Hitomi  高田 仁実

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Researcher Number 80641068
Other IDs
Affiliation (Current) 2025: 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教
Affiliation (based on the past Project Information) *help 2017 – 2024: 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教
2017: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教
2015 – 2016: 国立研究開発法人産業技術総合研究所, 創薬基盤研究部門, 研究員
2014: 独立行政法人 産業技術総合研究所, 幹細胞工学研究センター, 研究員
2013 – 2014: 独立行政法人産業技術総合研究所, 幹細胞工学研究センター, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 48010:Anatomy-related / Basic Section 56070:Plastic and reconstructive surgery-related / Biomedical engineering/Biomaterial science and engineering
Except Principal Investigator
Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90110:Biomedical engineering-related / Medical genome science / Biomedical engineering/Biomaterial science and engineering / Drug development chemistry / Medical genome science
Keywords
Principal Investigator
下肢虚血 / 細胞移植 / 再生医療 / 間葉系幹細胞 / 幹細胞分化 / リモデリング / 炎症 / 組織幹細胞 / 消化管 / オルガノイド … More / 再生 / 幹細胞 / 萎縮性胃炎 / 胃潰瘍 / 脂肪組織 / 血管新生 / 組織再生 / 培養技術 / 分泌性因子 / シングルセル解析 / 虚血性疾患 / 細胞培養技術 / 皮下脂肪 / 脂肪組織由来細胞 / 細胞移植治療 / 1細胞解析 … More
Except Principal Investigator
遺伝子 / 分化 / 幹細胞 / 肺 / 再生 / 前駆細胞 / 胃 / 転写因子 / 細胞 / 上皮細胞 / 発生 / がん / ES細胞 / 移植・再生医療 / 発生・分化 / iPS細胞 / 再生医学 / 培養 / シグナル / 線維芽細胞 / 移植 / オルガノイド / 蛋白質 / 疾患 / タンパク / アポトーシス / 化合物 / マイクロアレイ / 癌 / 治療薬 / 間葉系 / メカニズム / 表面マーカー / 間葉系幹細胞 / 細胞・組織 / 呼吸器 Less
  • Research Projects

    (14 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (8 People)
  •  Development of an innovative technology for the lung tissue regeneration

    • Principal Investigator
      栗崎 晃
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Nara Institute of Science and Technology
  •  Development of fundamental technologies for stomach tissue regeneration

    • Principal Investigator
      栗崎 晃
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Nara Institute of Science and Technology
  •  炎症が惹起する病的胃腺リモデリングの分子実態解明Principal Investigator

    • Principal Investigator
      高田 仁実
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48010:Anatomy-related
    • Research Institution
      Nara Institute of Science and Technology
  •  Development of innovative therapy for intractable lung diseases

    • Principal Investigator
      Kurisaki Akira
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Nara Institute of Science and Technology
  •  Improvement of the lung tissue differentiation method and development of the gene therapy technology

    • Principal Investigator
      Kurisaki Akira
    • Project Period (FY)
      2020 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Nara Institute of Science and Technology
  •  Development of fundamental technologies for stomach tissue regeneration

    • Principal Investigator
      Kurisaki Akira
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Nara Institute of Science and Technology
  •  Functional enhancement of MSCs based on analysis of expression profiles of secreted factorsPrincipal Investigator

    • Principal Investigator
      Hitomi Takada
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56070:Plastic and reconstructive surgery-related
    • Research Institution
      Nara Institute of Science and Technology
  •  A novel gene therapy method for the lung regeneration

    • Principal Investigator
      Kurisaki AKIRA
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 90:Biomedical engineering and related fields
    • Research Institution
      Nara Institute of Science and Technology
  •  Pathological analysis and drug discovery for stomach cancer using human stomach organoids

    • Principal Investigator
      Kurisaki AKIRA
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Nara Institute of Science and Technology
  •  Characterization of adipose tissue derived stromal vascular fraction cells with high angiogenic potentialPrincipal Investigator

    • Principal Investigator
      TAKADA Hitomi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      Nara Institute of Science and Technology
      National Institute of Advanced Industrial Science and Technology
  •  Elucidation of the mechanisms of a novel recurrent-resistant anticancer drug

    • Principal Investigator
      Kurisaki Akira
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Drug development chemistry
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Development of tissue regeneration technology of respiratory system

    • Principal Investigator
      Kurisaki Akira
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical genome science
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Elucidaton of the regulatory mechanisms of mesenchymal stem cells by screening cDNA library

    • Principal Investigator
      AKIRA Kurisaki
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical genome science
    • Research Institution
      National Institute of Advanced Industrial Science and Technology
  •  Development of a lung regeneration method with lung precursor cells

    • Principal Investigator
      Kurisaki Akira
    • Project Period (FY)
      2011 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Medical genome science
    • Research Institution
      National Institute of Advanced Industrial Science and Technology

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation Book Patent

  • [Book] オルガノイド実験スタンダード (12章 胃オルガノイド)2019

    • Author(s)
      栗崎晃、高田仁実(分担執筆)
    • Total Pages
      368
    • Publisher
      羊土社
    • ISBN
      9784758122399
    • Data Source
      KAKENHI-PROJECT-17H00861
  • [Journal Article] 胃オルガノイドによるマイ・メディシン2021

    • Author(s)
      栗崎晃、高田仁実
    • Journal Title

      医学のあゆみ

      Volume: 276 Pages: 585-589

    • Data Source
      KAKENHI-PROJECT-20H04505
  • [Journal Article] 胃オルガノイドによるマイ・メディシン2021

    • Author(s)
      栗崎晃、高田仁実
    • Journal Title

      別冊・医学のあゆみ

      Volume: 1 Pages: 27-31

    • Data Source
      KAKENHI-PROJECT-20H04505
  • [Journal Article] 胃オルガノイド作製と病態モデル2019

    • Author(s)
      栗崎晃、高田仁実
    • Journal Title

      Medical Science Direct

      Volume: 45 Pages: 14-17

    • Data Source
      KAKENHI-PROJECT-17H00861
  • [Journal Article] Quartz-Seq2: a high-throughput single-cell RNA-sequencing method that effectively uses limited sequence reads2018

    • Author(s)
      Sasagawa Yohei、Danno Hiroki、Takada Hitomi、Ebisawa Masashi、Tanaka Kaori、Hayashi Tetsutaro、Kurisaki Akira、Nikaido Itoshi
    • Journal Title

      Genome Biology

      Volume: 19 Issue: 1 Pages: 1-24

    • DOI

      10.1186/s13059-018-1407-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K16329, KAKENHI-PROJECT-24651218, KAKENHI-PROJECT-17H00861
  • [Journal Article] A role for KLF4 in promoting the metabolic shift via TCL1 during induced pluripotent stem cell generation.2017

    • Author(s)
      Nishimura K, Aizawa S, Nugroho FL, Shiomitsu E, Tran YTH, Bui PL, Borisova E, Sakuragi Y, Takada H, Kurisaki A, Hayashi Y, Fukuda A, Nakanishi M, Hisatake K
    • Journal Title

      Stem Cell Reports

      Volume: 8 Issue: 3 Pages: 787-801

    • DOI

      10.1016/j.stemcr.2017.01.026

    • NAID

      120007129229

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07244, KAKENHI-PROJECT-16K08610, KAKENHI-PROJECT-15K14986, KAKENHI-PROJECT-26290068
  • [Journal Article] Therapeutic Potential of Human Adipose-Derived Stem/Stromal Cell Microspheroids Prepared by Three-Dimensional Culture in Non-Cross-Linked Hyaluronic Acid Gel.2015

    • Author(s)
      Mineda K, Feng J, Ishimine H, Takada H, Doi K, Kuno S, Kinoshita K, Kanayama K, Kato H, Mashiko T, Hashimoto I, Nakanishi H, Kurisaki A, Yoshimura K.
    • Journal Title

      Stem Cells Transl Med

      Volume: 12 Pages: 1511-1522

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K16329
  • [Patent] 胃幹細胞培養用培地、培養方法2023

    • Inventor(s)
      栗崎晃、高田仁美
    • Industrial Property Rights Holder
      栗崎晃、高田仁美
    • Industrial Property Rights Type
      特許
    • Filing Date
      2023
    • Data Source
      KAKENHI-PROJECT-22K06789
  • [Presentation] Generation of gastric organoids from mouse embryonic stem cells2022

    • Author(s)
      Thi Thuy Linh Trinh, Hitomi Takada, Akira Kurisaki
    • Organizer
      第55回 日本発生生物学会
    • Data Source
      KAKENHI-PROJECT-20H04505
  • [Presentation] Molecular Mechanisms Underlying Gastric Stem Cell Differentiation during adult tissue homeostasis2020

    • Author(s)
      高田仁実
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20H04505
  • [Presentation] 成熟胃オルガノイドの分化培養条件検討2019

    • Author(s)
      黒岩隆史、高田仁実、栗崎晃
    • Organizer
      第42回 日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-17H00861
  • [Presentation] 成熟胃オルガノイドの分化培養条件検討2019

    • Author(s)
      黒岩隆史、高田仁実、栗崎晃
    • Organizer
      日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-19K10029
  • [Presentation] THE GLOBAL PICTURE OF CELL-TYPE COMPOSITION IN THE STROMAL VASCULAR FRACTION PREPARED FROM MOUSE ADIPOSE TISSUE2018

    • Author(s)
      Hitomi Takada, Yohei Sasagawa, Hiroki Danno, Masashi Ebisawa, Kaori Tanaka, Tetsutaro Hayashi, Itoshi Nikaido, Akira Kurisaki
    • Organizer
      ISSCR
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K16329
  • [Presentation] THE GLOBAL PICTURE OF CELL-TYPE COMPOSITION IN THE STROMAL VASCULAR FRACTION PREPARED FROM MOUSE ADIPOSE TISSUE2018

    • Author(s)
      Hitomi Takada, Yohei Sasagawa, Hiroki Danno, Masashi Ebisawa, Kaori Tanaka,Tetsutaro Hayashi, Itoshi Nikaido, Akira Kurisaki
    • Organizer
      International Society for Stem Cell Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H00861
  • [Presentation] Spheroid culture condition optimally expands angiogenic cells of adipose derived-stromal vascular fraction2016

    • Author(s)
      Hitomi Takada, Yasuyuki Kida, Akira Kurisaki
    • Organizer
      ISSCR
    • Place of Presentation
      San Francisco, USA
    • Year and Date
      2016-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K16329
  • [Presentation] Spheroid Culture Condition Optimally Expands Angiogenic Cells of Adipose Tissue-Derived Stromal Vascular Fraction.2016

    • Author(s)
      Hitomi Takada, Yasuyuki Kida, Akira Kurisaki
    • Organizer
      International Society for Stem Cell Research
    • Place of Presentation
      Moscone West (San Francisco, USA)
    • Year and Date
      2016-06-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K16329
  • [Presentation] Methylome, transcriptome, and PPARγ cistrome analyses reveal two epigenetic transitions in fat cells2015

    • Author(s)
      Hitomi Takada, Yutaka Saito, Toutai Mituyama, Zong Wei, Eiji Yoshihara, Sandra Jacinto, Michael Downs, Ronald M Evans, Yasu-yuki Kida
    • Organizer
      ISSCR
    • Place of Presentation
      Stockholm, Sweden
    • Year and Date
      2015-06-24
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K16329
  • 1.  Kurisaki Akira (60346616)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 7 results
  • 2.  印東 厚 (70779058)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  ISHIMINE Hisako (90736737)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  Hashimoto Osamu (90317058)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  中島 由郎 (30455430)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  原本 悦和 (30540869)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  畠山 昌則 (40189551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  西村 健
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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