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Mukaiyama Atsushi  向山 厚

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MUKAIYAMA Atsushi  向山 厚

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Researcher Number 80647446
Other IDs
Affiliation (Current) 2023: 福井県立大学, 生物資源学部, 准教授
Affiliation (based on the past Project Information) *help 2023: 福井県立大学, 生物資源学部, 准教授
2018 – 2022: 分子科学研究所, 協奏分子システム研究センター, 助教
2013 – 2015: 分子科学研究所, 協奏分子システム研究センター, 助教
Review Section/Research Field
Principal Investigator
Basic Section 43040:Biophysics-related / Biophysics / Transformative Research Areas, Section (III)
Except Principal Investigator
Biophysics / Transformative Research Areas, Section (III) / Broad Section G
Keywords
Principal Investigator
時計タンパク質 / 概日時計 / 生物時計 / KaiC / ATPase / 進化・多様性 / タンパク質 / 構造変化 / 概日リズム / シアノバクテリア / 分子進化 / 周波数特性 / KaiCホモログ … More
Except Principal Investigator
… More 概日時計 / タンパク質 / 物質輸送 / 生物時計 / タイミング / 生化学 / 質量分析 / リン酸化 / 翻訳後修飾 / 睡眠 / 時間タンパク質学 / シアノバクテリア Less
  • Research Projects

    (7 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (12 People)
  •  原始概日時計の試験管内再構成Principal Investigator

    • Principal Investigator
      向山 厚
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Institute for Molecular Science
  •  Simplifying complexity and diversity of circadian clocks

    • Principal Investigator
      秋山 修志
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (S)
    • Review Section
      Broad Section G
    • Research Institution
      Institute for Molecular Science
  •  Chrono-proteinology: principle and design for protein timers

    • Principal Investigator
      吉種 光
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Tokyo Metropolitan Institute of Medical Science
  •  時間タンパク質学:生命の時間を宿す機能的KaiCホモログの探索技術の開発Principal Investigator

    • Principal Investigator
      向山 厚
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Fukui Prefectural University
      Institute for Molecular Science
  •  Exploring the mechanism behind environmental adaptation of circadian clock in cyanobacteriaPrincipal Investigator

    • Principal Investigator
      Mukaiyama Atsushi
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Institute for Molecular Science
  •  Development of a drug delivery system equipped with timer

    • Principal Investigator
      AKIYAMA Shuji
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Biophysics
    • Research Institution
      Institute for Molecular Science
  •  Structural transition of the cyanobacterial clock protein KaiC in solutionPrincipal Investigator

    • Principal Investigator
      MUKAIYAMA Atsushi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      Institute for Molecular Science

All 2022 2021 2019 2018 2015 2014 Other

All Journal Article Presentation Book

  • [Book] Biological Rhythms2019

    • Author(s)
      Mukaiyama A, Furuike Y and AkiyamaS (分担執筆)
    • Total Pages
      164
    • Publisher
      北海道大学出版会
    • ISBN
      9784832903746
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Journal Article] Adenylate kinase 1 overexpression increases locomotor activity in medaka fish2022

    • Author(s)
      Maruyama Michiyo、Furukawa Yuko、Kinoshita Masato、Mukaiyama Atsushi、Akiyama Shuji、Yoshimura Takashi
    • Journal Title

      PLOS ONE

      Volume: 17 Issue: 1 Pages: e0257967-e0257967

    • DOI

      10.1371/journal.pone.0257967

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-19H05643, KAKENHI-PROJECT-20K20459
  • [Journal Article] Slow and temperature-compensated autonomous disassembly of KaiB–KaiC complex2022

    • Author(s)
      Simon Damien、Mukaiyama Atsushi、Furuike Yoshihiko、Akiyama Shuji
    • Journal Title

      Biophysics and Physicobiology

      Volume: 19 Issue: 0 Pages: n/a

    • DOI

      10.2142/biophysico.bppb-v19.0008

    • ISSN
      2189-4779
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K16061, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-17H06165
  • [Journal Article] Development and optimization of expression, purification and ATPase assay of KaiC for medium throughput screening of circadian clock mutants in cyanobacteria2019

    • Author(s)
      Ouyang D, Furuike Y, Mukaiyama A, Ito-Miwa K, Kondo T and Akiyama S
    • Journal Title

      Int. J. Mol. Sci.

      Volume: 20 Issue: 11 Pages: 2789-2789

    • DOI

      10.3390/ijms20112789

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06171, KAKENHI-PROJECT-19K16061, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-17H01427
  • [Journal Article] KaiC from a cyanobacterium Gloeocapsa sp. PCC 7428 retains functional and structural properties required as the core of circadian clock system.2019

    • Author(s)
      Mukaiyama A, Ouyang D, Furuike Y, Akiyama S
    • Journal Title

      International Journal of Biological Macromolecules

      Volume: 131 Pages: 67-73

    • DOI

      10.1016/j.ijbiomac.2019.03.051

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06171, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-16K14685, KAKENHI-PROJECT-19K16061
  • [Journal Article] Conformational rearrangements of the C1 ring in KaiC measure the timing of assembly with KaiB2018

    • Author(s)
      Mukaiyama A, Furuike Y, Abe J, Yamashita E, Kondo T, Akiyama S
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 8803-8803

    • DOI

      10.1038/s41598-018-27131-8

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06171, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-16K14685
  • [Journal Article] A protocol for preparing nucleotide-free KaiC monomer2015

    • Author(s)
      Mukaiyama, A., Osako, M., Hikima, T., Kondo, T., and Akiyama, S.
    • Journal Title

      BIOPHYSICS

      Volume: 11 Issue: 0 Pages: 79-84

    • DOI

      10.2142/biophysics.11.79

    • NAID

      130004940817

    • ISSN
      1349-2942
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24000016, KAKENHI-PROJECT-25291039, KAKENHI-PROJECT-25840058, KAKENHI-PUBLICLY-26102544
  • [Presentation] 分子進化的アプローチに基づく概日時計の進化的起源の探究2022

    • Author(s)
      向山 厚、古池 美彦、秋山 修志
    • Organizer
      令和3年度日本物理学会中部支部講演会
    • Data Source
      KAKENHI-PLANNED-21H05132
  • [Presentation] Disassembly kinetics of the KaiBC complex in the cyanobacterial clock system2021

    • Author(s)
      D. Simon, A. Mukaiyama, Y. Furuike and S. Akiyama
    • Organizer
      令和2年度生物物理中部支部講演会
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] Exploring ancient origin of circadian oscillation through KaiC evolution2021

    • Author(s)
      Mukaiyama A, Furuike Y, Akiyama S
    • Organizer
      第59回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PLANNED-21H05132
  • [Presentation] シアノバクテリア概日時計における進化的多様性の分子メカニズム2021

    • Author(s)
      向山 厚、古池 美彦、秋山 修志
    • Organizer
      令和2年度生物物理中部支部講演会
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] Seeking for evolutionary diversity of Kai-protein clock system in cyanobacteria2019

    • Author(s)
      Mukaiyama A, Ouyang D, Furuike Y and Akiyama S
    • Organizer
      XVI European biological rhythm society congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] Evolutionary diversity of Kai-protein clock in cyanobacteria2019

    • Author(s)
      Mukaiyama A, Ouyang D, Furuike Y and Akiyama S
    • Organizer
      第57回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] 他種KaiCの機能解析から探るシアノバクテリア生物時計システムの進化的多様性2019

    • Author(s)
      向山 厚、秋山 修志
    • Organizer
      第26回日本時間生物学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] シアノバクテリアGloeocapsa sp. PCC 7428株由来KaiCの機能解析2019

    • Author(s)
      向山 厚、欧陽 東彦、古池 美彦、秋山 修志
    • Organizer
      平成30年度日本生物物理学会中部支部講演会
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] 機能解析から探るKaiタンパク質時計システムの進化的多様性2019

    • Author(s)
      向山 厚
    • Organizer
      Cyanoclock2.0
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] 多種KaiCの機能解析によるシアノバクテリア生物時計の進化的多様性の考察2019

    • Author(s)
      向山 厚、欧陽 東彦、古池 美彦、秋山 修志
    • Organizer
      第19回日本蛋白質科学会年会
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] シアノバクテリア生物時計の分子起源とその進化2018

    • Author(s)
      向山 厚、古池 美彦、秋山 修志
    • Organizer
      第25回日本時間生物学会学術大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] Conformational rearrangements of the C1 ring in KaiC measure the timing of assembly with KaiB via a conformational selection mechanism2018

    • Author(s)
      Atsushi Mukaiyama, Yoshihiko Furuike, Eiki Yamashita, Takao Kondo and Shuji Akiyama
    • Organizer
      第56回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-18K06171
  • [Presentation] 蛍光分光法による時計タンパク質KaiCのN末端リングの構造変化の解析2015

    • Author(s)
      向山 厚
    • Organizer
      平成26年度日本生物物理学会中部支部講演会
    • Place of Presentation
      岡崎コンファレンスセンター、愛知県岡崎市
    • Year and Date
      2015-03-10
    • Data Source
      KAKENHI-PROJECT-25840058
  • [Presentation] 蛍光分光法による時計タンパク質KaiCの構造変化の解析2014

    • Author(s)
      向山厚、秋山修志
    • Organizer
      第14回日本蛋白質科学会年会
    • Place of Presentation
      ワークピア横浜、神奈川県
    • Data Source
      KAKENHI-PROJECT-25840058
  • [Presentation] Conformational transition of a cyanobacterial clock protein KaiC monitored with fluorescence spectroscopy

    • Author(s)
      Atsushi Mukaiyama, Shuji Akiyama
    • Organizer
      第52回日本生物物理学会年会
    • Place of Presentation
      札幌コンベンションセンター、北海道札幌市
    • Year and Date
      2014-09-25 – 2014-09-27
    • Data Source
      KAKENHI-PROJECT-25840058
  • [Presentation] 蛍光分光法によるシアノバクテリア時計タンパク質KaiCの構造変化の解析

    • Author(s)
      向山 厚、秋山 修志
    • Organizer
      第14回日本蛋白質科学会年会
    • Place of Presentation
      ワークピア横浜、神奈川県横浜市
    • Year and Date
      2014-06-25 – 2014-06-27
    • Data Source
      KAKENHI-PROJECT-25840058
  • 1.  AKIYAMA Shuji (50391842)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 2.  八木田 和弘 (90324920)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  吉種 光 (70569920)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  松尾 拓哉 (00452201)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  大出 晃士 (40612122)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  村中 智明 (50761938)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  戸田 浩史 (80862010)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  近藤 孝男 (10124223)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  藤原 悟 (10354888)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  上久保 裕生 (20311128)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  成田 哲博 (30360613)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  古池 美彦 (70757400)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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