Mukaiyama Atsushi 向山厚

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MUKAIYAMA Atsushi 向山厚

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Researcher Number	80647446
Other IDs
Affiliation (Current)	2023: 福井県立大学, 生物資源学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 福井県立大学, 生物資源学部, 准教授 2018 – 2022: 分子科学研究所, 協奏分子システム研究センター, 助教 2013 – 2015: 分子科学研究所, 協奏分子システム研究センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 43040:Biophysics-related / Biophysics / Transformative Research Areas, Section (III) Except Principal Investigator Biophysics / Transformative Research Areas, Section (III) / Broad Section G
Keywords	Principal Investigator 時計タンパク質 / 概日時計 / 生物時計 / KaiC / ATPase / 進化・多様性 / タンパク質 / 構造変化 / 概日リズム / シアノバクテリア / 分子進化 / 周波数特性 / KaiCホモログ … More Except Principal Investigator … More 概日時計 / タンパク質 / 物質輸送 / 生物時計 / タイミング / 生化学 / 質量分析 / リン酸化 / 翻訳後修飾 / 睡眠 / 時間タンパク質学 / シアノバクテリア Less

原始概日時計の試験管内再構成Principal Investigator
- Principal Investigator
  
  向山厚
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Institute for Molecular Science
Simplifying complexity and diversity of circadian clocks
- Principal Investigator
  
  秋山修志
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Review Section
  
  Broad Section G
- Research Institution
  Institute for Molecular Science
Chrono-proteinology: principle and design for protein timers
- Principal Investigator
  
  吉種光
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
時間タンパク質学：生命の時間を宿す機能的KaiCホモログの探索技術の開発Principal Investigator
- Principal Investigator
  
  向山厚
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Fukui Prefectural University
  Institute for Molecular Science
Exploring the mechanism behind environmental adaptation of circadian clock in cyanobacteriaPrincipal Investigator
- Principal Investigator
  
  Mukaiyama Atsushi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Institute for Molecular Science
Development of a drug delivery system equipped with timer
- Principal Investigator
  
  AKIYAMA Shuji
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  Institute for Molecular Science
Structural transition of the cyanobacterial clock protein KaiC in solutionPrincipal Investigator
- Principal Investigator
  
  MUKAIYAMA Atsushi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biophysics
- Research Institution
  Institute for Molecular Science

All 2022 2021 2019 2018 2015 2014 Other

All Journal Article Presentation Book

[Book] Biological Rhythms2019
- Author(s)
  Mukaiyama A, Furuike Y and AkiyamaS (分担執筆）
- Total Pages
  164
- Publisher
  北海道大学出版会
- ISBN
  9784832903746
- Data Source
  KAKENHI-PROJECT-18K06171
[Journal Article] Adenylate kinase 1 overexpression increases locomotor activity in medaka fish2022
- Author(s)
  Maruyama Michiyo、Furukawa Yuko、Kinoshita Masato、Mukaiyama Atsushi、Akiyama Shuji、Yoshimura Takashi
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 1 Pages: e0257967-e0257967
- DOI
  10.1371/journal.pone.0257967
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-19H05643, KAKENHI-PROJECT-20K20459
[Journal Article] Slow and temperature-compensated autonomous disassembly of KaiB–KaiC complex2022
- Author(s)
  Simon Damien、Mukaiyama Atsushi、Furuike Yoshihiko、Akiyama Shuji
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 19 Issue: 0 Pages: n/a
- DOI
  10.2142/biophysico.bppb-v19.0008
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16061, KAKENHI-PLANNED-21H05132, KAKENHI-PROJECT-17H06165
[Journal Article] Development and optimization of expression, purification and ATPase assay of KaiC for medium throughput screening of circadian clock mutants in cyanobacteria2019
- Author(s)
  Ouyang D, Furuike Y, Mukaiyama A, Ito-Miwa K, Kondo T and Akiyama S
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 20 Issue: 11 Pages: 2789-2789
- DOI
  10.3390/ijms20112789
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06171, KAKENHI-PROJECT-19K16061, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-17H01427
[Journal Article] KaiC from a cyanobacterium Gloeocapsa sp. PCC 7428 retains functional and structural properties required as the core of circadian clock system.2019
- Author(s)
  Mukaiyama A, Ouyang D, Furuike Y, Akiyama S
- Journal Title
  
  International Journal of Biological Macromolecules
  
  Volume: 131 Pages: 67-73
- DOI
  10.1016/j.ijbiomac.2019.03.051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06171, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-16K14685, KAKENHI-PROJECT-19K16061
[Journal Article] Conformational rearrangements of the C1 ring in KaiC measure the timing of assembly with KaiB2018
- Author(s)
  Mukaiyama A, Furuike Y, Abe J, Yamashita E, Kondo T, Akiyama S
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 8803-8803
- DOI
  10.1038/s41598-018-27131-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06171, KAKENHI-PROJECT-17H06165, KAKENHI-PROJECT-16K14685
[Journal Article] A protocol for preparing nucleotide-free KaiC monomer2015
- Author(s)
  Mukaiyama, A., Osako, M., Hikima, T., Kondo, T., and Akiyama, S.
- Journal Title
  
  BIOPHYSICS
  
  Volume: 11 Issue: 0 Pages: 79-84
- DOI
  10.2142/biophysics.11.79
- NAID
  130004940817
- ISSN
  1349-2942
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24000016, KAKENHI-PROJECT-25291039, KAKENHI-PROJECT-25840058, KAKENHI-PUBLICLY-26102544
[Presentation] 分子進化的アプローチに基づく概日時計の進化的起源の探究2022
- Author(s)
  向山厚、古池美彦、秋山修志
- Organizer
  令和3年度日本物理学会中部支部講演会
- Data Source
  KAKENHI-PLANNED-21H05132
[Presentation] Disassembly kinetics of the KaiBC complex in the cyanobacterial clock system2021
- Author(s)
  D. Simon, A. Mukaiyama, Y. Furuike and S. Akiyama
- Organizer
  令和2年度生物物理中部支部講演会
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] Exploring ancient origin of circadian oscillation through KaiC evolution2021
- Author(s)
  Mukaiyama A, Furuike Y, Akiyama S
- Organizer
  第59回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-21H05132
[Presentation] シアノバクテリア概日時計における進化的多様性の分子メカニズム2021
- Author(s)
  向山　厚、古池　美彦、秋山　修志
- Organizer
  令和2年度生物物理中部支部講演会
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] Seeking for evolutionary diversity of Kai-protein clock system in cyanobacteria2019
- Author(s)
  Mukaiyama A, Ouyang D, Furuike Y and Akiyama S
- Organizer
  XVI European biological rhythm society congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] Evolutionary diversity of Kai-protein clock in cyanobacteria2019
- Author(s)
  Mukaiyama A, Ouyang D, Furuike Y and Akiyama S
- Organizer
  第57回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] 他種KaiCの機能解析から探るシアノバクテリア生物時計システムの進化的多様性2019
- Author(s)
  向山厚、秋山修志
- Organizer
  第26回日本時間生物学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] シアノバクテリアGloeocapsa sp. PCC 7428株由来KaiCの機能解析2019
- Author(s)
  向山　厚、欧陽　東彦、古池　美彦、秋山　修志
- Organizer
  平成30年度日本生物物理学会中部支部講演会
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] 機能解析から探るKaiタンパク質時計システムの進化的多様性2019
- Author(s)
  向山厚
- Organizer
  Cyanoclock2.0
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] 多種KaiCの機能解析によるシアノバクテリア生物時計の進化的多様性の考察2019
- Author(s)
  向山厚、欧陽東彦、古池美彦、秋山修志
- Organizer
  第19回日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] シアノバクテリア生物時計の分子起源とその進化2018
- Author(s)
  向山　厚、古池　美彦、秋山　修志
- Organizer
  第25回日本時間生物学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] Conformational rearrangements of the C1 ring in KaiC measure the timing of assembly with KaiB via a conformational selection mechanism2018
- Author(s)
  Atsushi Mukaiyama, Yoshihiko Furuike, Eiki Yamashita, Takao Kondo and Shuji Akiyama
- Organizer
  第56回日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-18K06171
[Presentation] 蛍光分光法による時計タンパク質KaiCのN末端リングの構造変化の解析2015
- Author(s)
  向山　厚
- Organizer
  平成26年度日本生物物理学会中部支部講演会
- Place of Presentation
  岡崎コンファレンスセンター、愛知県岡崎市
- Year and Date
  2015-03-10
- Data Source
  KAKENHI-PROJECT-25840058
[Presentation] 蛍光分光法による時計タンパク質KaiCの構造変化の解析2014
- Author(s)
  向山厚、秋山修志
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  ワークピア横浜、神奈川県
- Data Source
  KAKENHI-PROJECT-25840058
[Presentation] Conformational transition of a cyanobacterial clock protein KaiC monitored with fluorescence spectroscopy
- Author(s)
  Atsushi Mukaiyama, Shuji Akiyama
- Organizer
  第52回日本生物物理学会年会
- Place of Presentation
  札幌コンベンションセンター、北海道札幌市
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25840058
[Presentation] 蛍光分光法によるシアノバクテリア時計タンパク質KaiCの構造変化の解析
- Author(s)
  向山厚、秋山修志
- Organizer
  第14回日本蛋白質科学会年会
- Place of Presentation
  ワークピア横浜、神奈川県横浜市
- Year and Date
  2014-06-25 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25840058

1. AKIYAMA Shuji (50391842)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 八木田和弘 (90324920)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 吉種光 (70569920)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 松尾拓哉 (00452201)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 大出晃士 (40612122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 村中智明 (50761938)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 戸田浩史 (80862010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 近藤孝男 (10124223)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 藤原悟 (10354888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 上久保裕生 (20311128)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 成田哲博 (30360613)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 古池美彦 (70757400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Mukaiyama Atsushi 向山 厚

MUKAIYAMA Atsushi 向山 厚

Research Projects

Research Products

Co-Researchers

原始概日時計の試験管内再構成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Simplifying complexity and diversity of circadian clocks

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Chrono-proteinology: principle and design for protein timers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

時間タンパク質学：生命の時間を宿す機能的KaiCホモログの探索技術の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploring the mechanism behind environmental adaptation of circadian clock in cyanobacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a drug delivery system equipped with timer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural transition of the cyanobacterial clock protein KaiC in solutionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Biological Rhythms2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Adenylate kinase 1 overexpression increases locomotor activity in medaka fish2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Slow and temperature-compensated autonomous disassembly of KaiB–KaiC complex2022

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Development and optimization of expression, purification and ATPase assay of KaiC for medium throughput screening of circadian clock mutants in cyanobacteria2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KaiC from a cyanobacterium Gloeocapsa sp. PCC 7428 retains functional and structural properties required as the core of circadian clock system.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Conformational rearrangements of the C1 ring in KaiC measure the timing of assembly with KaiB2018

Author(s)

Journal Title

DOI

Data Source

Mukaiyama Atsushi 向山厚

MUKAIYAMA Atsushi 向山厚