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KOBAYASHI Kenya  小林 謙也

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kobayashi kenya  小林 謙也

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Researcher Number 80648311
Affiliation (Current) 2023: 東京大学, 医学部附属病院, 助教
Affiliation (based on the past Project Information) *help 2021 – 2022: 東京大学, 医学部附属病院, 助教
2019 – 2020: 国立研究開発法人国立がん研究センター, 中央病院, 医長
2016 – 2018: 東京大学, 医学部附属病院, 登録研究医
2015: 東京大学, 医学部附属病院, 特任研究医
2014: 東京大学, 医学部附属病院, 登録研究員
2013: 東京大学, 医学部附属病院, 登録研究医
Review Section/Research Field
Principal Investigator
Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology
Keywords
Principal Investigator
腺様嚢胞癌 / 神経周囲浸潤 / 神経栄養因子 / PDS / 高悪性転化 / サブクローン進化 / ゲノム / ゲノム進化 / 頭頸部扁平上皮癌 / TP53 … More / 腫瘍内不均一性 / ゲノム解析 / 頭頸部癌 / PD-L1 / NTRK / PD-L1 / 癒合遺伝子 / PDL1 / 免疫逃避機構 / MYB-NFIB癒合遺伝子 / MYB-NFIB融合遺伝子 / MYB過剰発現 / TrkA受容体 / NGF / MYB NFIB融合遺伝子 / TrkA / NGF / MYB-NFIB融合遺伝子 / MYB Less
  • Research Projects

    (4 results)
  • Research Products

    (43 results)
  • Co-Researchers

    (11 People)
  •  PDXモデルを用いた腺様嚢胞癌の起源・分化・高悪性化メカニズムの解明Principal Investigator

    • Principal Investigator
      小林 謙也
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      The University of Tokyo
  •  Intratumor heterogeneity in head and neck cancer by genomic, epigenomic, and transcriptomic analysis.Principal Investigator

    • Principal Investigator
      Kobayashi Kenya
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56050:Otorhinolaryngology-related
    • Research Institution
      The University of Tokyo
      National Cancer Center Japan
  •  Association of Nerve growth factor and Immune escape for Perineural invasion in Adenoid cystic carcinomaPrincipal Investigator

    • Principal Investigator
      Kobayashi Kenya
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      The University of Tokyo
  •  Nereve grrowth factor signals as possible pathogenic biomarkers for perineural invasion in adenoid cystic carcinomaPrincipal Investigator

    • Principal Investigator
      kobayashi kenya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Otorhinolaryngology
    • Research Institution
      The University of Tokyo

All 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book

  • [Book] 腺様嚢胞癌2021

    • Author(s)
      小林謙也
    • Publisher
      日本臨牀
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Book] JHONS 【治療法がめずらしい】嗅神経芽細胞腫2020

    • Author(s)
      小林謙也
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Book] 日本臨牀 肉腫ー基礎・臨床の最新動向ー軟部肉腫 頭頸部2020

    • Author(s)
      小林謙也
    • Publisher
      日本臨牀社
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Journal Article] Uniform infection screening allowed safe head and neck surgery during the coronavirus disease 2019 pandemic in Japan2021

    • Author(s)
      Akiko I, Kobayashi K, Shiotsuka M, Sato T, Omura G, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Takano T, Matsumot F, Kobayashi O, Iwata S, Yoshimoto S.
    • Journal Title

      Jpn J Clin Oncol .

      Volume: 51 Issue: 3 Pages: 400-407

    • DOI

      10.1093/jjco/hyaa195

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-18K09339
  • [Journal Article] Olfactory preservation in craniofacial resection of tumor invading hemianterior skull base: operative video.2021

    • Author(s)
      Kobayashi K, Miyakita Y, Matsumoto F, Omura G, Matsumura S, Ikeda A, Eguchi K, Ito A, Narita Y, Akazawa S, Yoshimoto S.
    • Journal Title

      J Neurol Surg B.

      Volume: -

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Journal Article] Carotid artery ligation via sternotomy as a palliative surgery: Case report of advanced inttramediastinal malignant soft tissue tumor.2021

    • Author(s)
      Eguchi K, Kobayashi K, Takano T, Ito A, Sakai A, Ikeda A, Matsumoto Y, Omura G, Matsumoto F, Yoshimoto S.
    • Journal Title

      Clin Case Rep.

      Volume: 9 Pages: 10-10

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Journal Article] Full-coverage TP53 deep sequencing of recurrent head and neck squamous cell carcinoma facilitates prognostic assessment after recurrence.2021

    • Author(s)
      Kobayashi K, Yoshimoto S, Ando M, Matsumoto F, Murakami N, Omura G, Honma Y, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Ito A, Ryo E, Yatabe Y, Mori T.
    • Journal Title

      Oral Oncol.

      Volume: 113 Pages: 105091-105091

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Journal Article] Uniform infection screening allowed safe head and neck surgery during the coronavirus disease 2019 pandemic in Japan.2021

    • Author(s)
      Ito A, Kobayashi K, Shiotsuka M, Sato T, Omura G, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Takano T, Matsumoto F, Kobayashi O, Iwata S, Yoshimoto S.
    • Journal Title

      Jpn J Clin Oncol.

      Volume: 51 Pages: 400-407

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Journal Article] Risk Factors for Delayed Surgical Recovery and Massive Bleeding in Skull Base Surgery.2020

    • Author(s)
      Kobayashi K, Matsumoto F, Miyakita Y, Arikawa M, Omura G, Matsumura S, Ikeda A, Sakai A, Eguchi K, Narita Y, Akazawa S, Miyamoto S, Yoshimoto S.
    • Journal Title

      Biomed Hub.

      Volume: 5 Issue: 2 Pages: 87-100

    • DOI

      10.1159/000507750

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K09339, KAKENHI-PROJECT-19K09923
  • [Journal Article] Full-coverage TP53 deep sequencing of recurrent head and neck squamous cell carcinoma facilitates prognostic assessment after recurrence.2020

    • Author(s)
      Kobayashi K, Yoshimoto S, Ando M, Matsumoto F, Murakami N, Omura G, Honma Y, Matsumoto Y, Ikeda A, Sakai A, Eguchi K, Ito A, Eigitsu R, Yatabe Y, Mori T.
    • Journal Title

      Oral oncology

      Volume: 113 Pages: 105091-105091

    • DOI

      10.1016/j.oraloncology.2020.105091

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-20K07383, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-18K09339
  • [Journal Article] All-Exon TP53 Sequencing and Protein Phenotype Analysis Accurately Predict Clinical Outcome after Surgical Treatment of Head and Neck Squamous Cell Carcinoma2019

    • Author(s)
      Kobayashi K, Yoshimoto S, Matsumoto F, Ando M, Murakami N, Omura G, Fukasawa M, Matsumoto Y, Matsumura M, Akamatsu M, Hiraoka N, Eigitsu R, and Mori T
    • Journal Title

      Annals of Surgical Oncology

      Volume: 印刷中 Issue: 7 Pages: 2294-2303

    • DOI

      10.1245/s10434-019-07287-x

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09339, KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-16K11246, KAKENHI-PROJECT-17K08710
  • [Journal Article] ASO Author Reflections: Precise p53 Analysis in Formalin-Fixed Paraffin-Embedded Specimens Can Predict Head and Neck Squamous Cell Carcinoma Outcomes2019

    • Author(s)
      Mori Taisuke、Kobayashi Kenya、Yoshimoto Seiichi
    • Journal Title

      Annals of Surgical Oncology

      Volume: 26 Issue: S3 Pages: 614-615

    • DOI

      10.1245/s10434-019-07433-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-17K08710
  • [Journal Article] A surgical approach to schwannomas originating from the esophageal branch of the recurrent laryngeal nerve: Pictorial essay.2019

    • Author(s)
      Kobayashi K, Matsumoto Y, Matsumoto F, Sato T, Mori T, Tsuchida T, Omura G, Matsumura S, Ikeda A, Sakai A, Eguchi K, and Yoshimoto S.
    • Journal Title

      Head Neck

      Volume: 41 Issue: 11 Pages: 4054-4059

    • DOI

      10.1002/hed.25921

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09339, KAKENHI-PROJECT-19K09923, KAKENHI-PROJECT-16K11246
  • [Journal Article] All-Exon TP53 Sequencing and Protein Phenotype Analysis Accurately Predict Clinical Outcome after Surgical Treatment of Head and Neck Squamous Cell Carcinoma.2019

    • Author(s)
      1.Kobayashi K, Yoshimoto S, Matsumoto F, Ando M, Murakami N, Omura G, Fukasawa M, Matsumoto Y, Matsumura S, Akamatsu M, Hiraoka N, Eigitsu R, Mori T.
    • Journal Title

      Ann Surg Oncol.

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Journal Article] Impact of Surgical Margin in Skull Base Surgery for Head and Neck Sarcomas.2018

    • Author(s)
      2.Kobayashi K, Matsumoto F, Miyakita Y, Mori T, Shimoi T, Murakami N, Yoshida A, Arakawa A, Omura G, Fukawasa M, Matsumoto Y, Matsumura S, Itami J, Narita Y, Yoshimoto S.
    • Journal Title

      J Neurol Surg B.

      Volume: 79(5) Pages: 437-444

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Journal Article] Impact of microscopic orbital periosteum invasion in orbital preservation surgery.2017

    • Author(s)
      Kobayashi K, Mori T, Matsumoto F, Murakami N, Teshima M, Fukasawa M, Matsumoto Y, Matsumura S, Itami J, Asai M, Yoshimoto S.
    • Journal Title

      Jpn J Clin Oncol.

      Volume: 47 Issue: 4 Pages: 321-327

    • DOI

      10.1093/jjco/hyw207

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26460463, KAKENHI-PROJECT-16K20232, KAKENHI-PROJECT-16K11246
  • [Journal Article] Significance of delayed primary excision in localized nonmetastatic adult head and neck rhabdomyosarcoma2016

    • Author(s)
      Kobayashi K, Matsumoto F, Kodaira M, Mori T, Murakami N, Yoshida A, Maki D, Teshima M, Fukasawa M, Itami J, Asai M, Yoshimoto S.
    • Journal Title

      Cancer Med.

      Volume: 5 Issue: 10 Pages: 2708-2714

    • DOI

      10.1002/cam4.855

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460463, KAKENHI-PROJECT-16K20232
  • [Presentation] High-grade transformationを起こした唾液腺明細胞癌のゲノム解析2021

    • Author(s)
      小林謙也、江口紘太郎、坂井梓、松本吉史、小村豪、吉本世一
    • Organizer
      第31回日本頭頸部外科学会
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Presentation] 患者由来腫瘍移植片モデルを用いた腺様嚢胞癌の進展機序の解明2021

    • Author(s)
      小林謙也
    • Organizer
      第122回日本耳鼻咽喉科学会
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Presentation] Establishment of Patient-Derived Xenografts of Adenoid Cystic Carcinoma with High-Grade Transformation2021

    • Author(s)
      Kenya Kobayashi, Taisuke Mori, Mizuo Ando, Yuki Saito, Hiroyuki Mano, Masahito Kawazu
    • Organizer
      第80回日本癌学会
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Presentation] 当科における耳下腺癌治療の顔面神経処理2021

    • Author(s)
      小林謙也、高野智誠、伊東明子、江口絋太郎、坂井梓、池田篤生、松本吉史、小村豪、吉本世一
    • Organizer
      第45回日本頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Presentation] 当院における小児悪性腫瘍の 治療経験2020

    • Author(s)
      小林謙也、江口紘太朗、坂井梓、池田篤生、松村聡子、小村豪、吉本世一
    • Organizer
      第30回頭頸部外科学会
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Presentation] 頭蓋底手術における嗅神経温存の工夫2020

    • Author(s)
      小林 謙也、伊東 明子、江口 紘太朗、坂井 梓、池田 篤生、松村 聡子、小村 豪、吉本 世一
    • Organizer
      頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Presentation] 当科における頭蓋底手術の切除および断端評価の工夫2019

    • Author(s)
      小林謙也 吉本世一 他
    • Organizer
      第29回頭頚部外科学会
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] 再発頭頸部扁平上皮癌におけるTP53変異の時系列解析2019

    • Author(s)
      小林謙也、森泰介昌、安藤瑞生、坂井梓、池田篤生、赤松摩紀、松村聡子、小村豪、松本文彦、吉本世一
    • Organizer
      第43回頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Presentation] Risk factors for delayed surgical recovery and massive bleeding in skull base surgery2019

    • Author(s)
      Kenya Kobayashi et al.
    • Organizer
      6th Congress of Asian Society of Head and Neck Oncology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] Risk factors for delayed surgical recovery and massive bleeding in skull base surgery.2019

    • Author(s)
      Kobayashi K, Matsumoto F, Miyakita Y, Moti T, Omura G, Fukasawa M, Matsumoto Y, Matsumuta S, Akamatsu M, Yoshimoto S
    • Organizer
      the 6th Asian society of head and neck oncology
    • Data Source
      KAKENHI-PROJECT-19K09923
  • [Presentation] 2.Clinical impact of combined p53 analysis with gene sequencing and immunostaining for head and neck squamous cell carcinoma.2018

    • Author(s)
      Kenya Kobayashi et al.
    • Organizer
      17th Korea-Japan Joint Meeting ORL-HNS
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] 1.Combined p53 analysis with gene sequencing and immunostaining for head and neck cancer.2018

    • Author(s)
      Kenya Kobayashi et al.
    • Organizer
      the 119th annual meeting of the ORL Society Japan
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] 予後不良なTP53ミスセンス変異の検討2018

    • Author(s)
      小林謙也 吉本世一 他
    • Organizer
      第42回頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] Impact of p53 status in surgical treatment of head and neck squamous cell carcinoma2017

    • Author(s)
      Kobayashi K, Mori T, Matsumoto F, Murakami N, Teshima M, Fukasawa M, Matsumoto Y, Matsumura S, Itami J, Asai M, Yoshimoto S.
    • Organizer
      5th congress of asian society of head and neck oncology
    • Place of Presentation
      Bali
    • Year and Date
      2017-03-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] 頭頸部扁平上皮癌の外科治療における p53免疫染色の意義2017

    • Author(s)
      小林 謙也、森 泰昌、松村 聡子、松本 吉史、深澤 雅彦、手島 直則、松本 文彦、吉本 世一
    • Organizer
      頭頸部外科学会
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] 免疫染色とシーケンスの併用による p53機能分類2017

    • Author(s)
      小林 謙也、森 泰昌、松村 聡子、松本 吉史、深澤 雅彦、手島 直則、松本 文彦、吉本 世一
    • Organizer
      日本頭頸部癌学会
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] Impact of p53 status in surgical treatment of head and neck squamous cell carcinoma2017

    • Author(s)
      Kenya Kobayashi, Taisuke Mori, Fumihiko Matsumoto, Masanori Teshima, Masahiko Fukasawa, Yoshifumi Matsumoto, Satoko Matsumura, Seiichi Yoshimoto
    • Organizer
      5th Congress of Asian Society of Head and Neck Oncology
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] 頭頸部扁平上皮癌の外科治療におけるp53免疫染色の意義2017

    • Author(s)
      小林 謙也、森 泰昌、松村 聡子、松本 吉史、深澤 雅彦、手島 直則、松本 文彦、吉本 世一
    • Organizer
      第27回日本頭頸部外科学会
    • Place of Presentation
      東京
    • Year and Date
      2017-02-02
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] Significance of surgery for head and neck sarcoma with skull base invasion2016

    • Author(s)
      Kenya Kobayashi
    • Organizer
      World Federation of Skull Base Societies
    • Place of Presentation
      大阪国際会議場 大阪府 大阪市
    • Year and Date
      2016-06-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25861533
  • [Presentation] Siginificance of surgery for head and neck sarcoma with skull base invasion2016

    • Author(s)
      Kenya Kobayashi, Yasuji Miyakita, Fumihiko Matsumoto, Makoto Kodaira, Taisuke Mori, Naoya Murakami, Daisuke Maki, Masanori Teshima, Masahiko Fukasawa, Yoshitaka Narita, Seiichi Yoshimoto
    • Organizer
      7th international congress of the World Federation of Skull Base Societies
    • Place of Presentation
      Osaka
    • Year and Date
      2016-06-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] 下顎骨浸潤を伴う口腔扁平上皮癌の臨床病理学的検討2016

    • Author(s)
      小林 謙也
    • Organizer
      第26回日本頭頸部外科学会
    • Place of Presentation
      名古屋国際会議場 愛知県 名古屋市
    • Year and Date
      2016-01-28
    • Data Source
      KAKENHI-PROJECT-25861533
  • [Presentation] 当院における頭蓋底浸潤を伴う肉腫の治療戦略2016

    • Author(s)
      小林謙也、宮北 康二、森 泰昌、吉田 明彦、下井 辰徳、松本 吉史、深澤 雅彦、手島 直則、松本 文彦、成田 善孝、吉本 世一
    • Organizer
      第40回日本頭頚部癌学会
    • Place of Presentation
      さいたま市
    • Year and Date
      2016-06-09
    • Data Source
      KAKENHI-PROJECT-16K20232
  • [Presentation] Treatment outcomes after orbital preservation surgery for cancers with orbital invasion2015

    • Author(s)
      Kenya Kobayashi
    • Organizer
      第39回頭頸部癌学会、第4回アジア頭頸部癌学会
    • Place of Presentation
      神戸国際会議場 兵庫県 神戸市
    • Year and Date
      2015-06-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-25861533
  • [Presentation] 腺様嚢胞癌における神経周囲浸潤と神経栄養因子の関係2014

    • Author(s)
      小林謙也
    • Organizer
      頭頸部外科学会
    • Place of Presentation
      高松
    • Data Source
      KAKENHI-PROJECT-25861533
  • [Presentation] 当科における腺様嚢胞癌の臨床検討2014

    • Author(s)
      小林 謙也
    • Organizer
      頭頸部癌学会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-25861533
  • [Presentation] Pathogenic biomarkers for perineural invasion in adenoid cystic carcinoma

    • Author(s)
      Kenya Kobayashi
    • Organizer
      AAO-HNSCF
    • Place of Presentation
      Orland, FL
    • Year and Date
      2014-09-21 – 2014-09-24
    • Data Source
      KAKENHI-PROJECT-25861533
  • 1.  安藤 瑞生 (60511467)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 2.  森 泰昌 (00296708)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 7 results
  • 3.  KONDO Kenji
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  SAITO Yuki
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  OMURA Go
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 6.  吉本 世一 (00462242)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 15 results
  • 7.  河津 正人 (20401078)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  YAMASOBA Tatsuya
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  ASAKAGE Takahiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  Yoshida Masahumi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 11.  Itami Jun
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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