Himeno Misao 姫野美沙緒

Researcher Number	80706416
Other IDs
Affiliation (Current)	2025: 東京大学, 大学院医学系研究科(医学部), 助教
Affiliation (based on the past Project Information) *help	2022 – 2024: 東京大学, 大学院医学系研究科(医学部), 助教 2020 – 2021: 東京大学, 定量生命科学研究所, 特別研究員 2018 – 2019: 東京大学, 定量生命科学研究所, 特任研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related Except Principal Investigator Basic Section 58020:Hygiene and public health-related: including laboratory approach
Keywords	Principal Investigator 肝非実質細胞 / 肝硬変 / 肝星細胞 / 三次元培養 / iPS細胞 / B型肝炎ウイルス / 抗HBV薬スクリーニング / 抗HBV薬 / レポーター / 抗ウイルス薬 … More / レポーターウイルス / 静止期星細胞 / B型肝炎ウイルス(HBV) / 薬剤スクリーニング / レポーターアッセイ / 三次元共培養 / 類洞内皮細胞 / 星細胞 … More Except Principal Investigator デングウイルス / 治療薬開発 / エピトープ / 免疫細胞 / フラビウイルス Less

Determination of T-B cell epitope for the development of novel anti-flavivirus therapeutic antibodies and contribution to a better understanding of pathogenesis
- Principal Investigator
  
  モイメンリン
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  The University of Tokyo
Construction and application of hepatitis B virus reporter system using fluorescence-activating proteinPrincipal Investigator
- Principal Investigator
  
  Himeno Misao
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo
Establishment of three dimensional HBV infection model which reflects the pathological progressionPrincipal Investigator
- Principal Investigator
  
  Himeno Misao
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] iPS細胞から肝類洞壁細胞への分化誘導法2021
- Author(s)
  姫野美沙緒、木戸丈友
- Total Pages
  7
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-20K17042
[Book] iPS細胞から肝類洞壁細胞への分化誘導法2021
- Author(s)
  姫野美沙緒、木戸丈友
- Total Pages
  7
- Publisher
  アークメディア
- Data Source
  KAKENHI-PROJECT-18K15773
[Journal Article] Utility of an In-Vitro Micro-Neutralizing Test in Comparison to a Plaque Reduction Neutralization Test for Dengue Virus, Japanese Encephalitis Virus, and Zika Virus Serology and Drug Screening2023
- Author(s)
  Haga Kazumi、Chen Zhenying (Nancy)、Himeno Misao、Majima Ryuichi、Moi Meng Ling
- Journal Title
  
  Pathogens
  
  Volume: 13 Issue: 1 Pages: 8-8
- DOI
  10.3390/pathogens13010008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17042
[Journal Article] Co-culture Model for Hepatitis B Virus Infection Using iPSC-Derived Liver Progenitor Cells and Liver Sinusoidal Endothelial Cells2022
- Author(s)
  Misao HIMENO, Shin-Wei Chen, Taketomo Kido
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 2544 Pages: 107-117
- DOI
  10.1007/978-1-0716-2557-6_7
- ISBN
  9781071625569, 9781071625576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17042, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-20J40236
[Journal Article] Development of human iPSC-derived quiescent hepatic stellate cell-like cells for drug discovery and in vitro disease modeling2021
- Author(s)
  Koui Yuta、Himeno Misao、Mori Yusuke、Nakano Yasuhiro、Saijou Eiko、Tanimizu Naoki、Kamiya Yoshiko、Anzai Hiroko、Maeda Natsuki、Wang Luyao、Yamada Tadanori、Sakai Yasuyuki、Nakato Ryuichiro、Miyajima Atsushi、Kido Taketomo
- Journal Title
  
  Stem Cell Reports
  
  Volume: 16 Issue: 12 Pages: 3050-3063
- DOI
  10.1016/j.stemcr.2021.11.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07958, KAKENHI-PROJECT-18K15773, KAKENHI-PROJECT-20J40236, KAKENHI-PLANNED-17H06331, KAKENHI-PROJECT-21H02710, KAKENHI-PROJECT-20K05843, KAKENHI-PROJECT-20K17042
[Journal Article] Modulation of hepatitis B virus infection by epidermal growth factor secreted from liver sinusoidal endothelial cells2020
- Author(s)
  Shin-Wei Chen, Misao Himeno, Yuta Koui, Masaya Sugiyama, Hironori Nishitsuji, Masashi Mizokami, Kunitada Shimotohno, Atsushi Miyajima, Taketomo Kido
- Journal Title
  
  Scientific Reports
  
  Volume: 10(1):14349 Issue: 1 Pages: 1-10
- DOI
  10.1038/s41598-020-71453-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15773, KAKENHI-PROJECT-20K17042, KAKENHI-PROJECT-18K07161, KAKENHI-PROJECT-19K22614
[Presentation] Development of anti-HBV agents that contain alkaloidal scaffolds bearing Michael acceptors2024
- Author(s)
  Misao Himeno, Kaneko Nobuto, Hiroki Kubota, Taketomo Kido, Atsushi Miyajima, Masaya Sugiyama, Meng Ling Moi, Hiroki Oguri
- Organizer
  The Joint 24th International Conference on Emerging Infectious Diseases in the Pacific Rim of the U.S.-Japan Cooperative Medical Sciences Program (USJCMSP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17042
[Presentation] マイケルアクセプターを有するアルカロイド類似化合物群の骨格多様化合成による抗B型肝炎ウイルス活性分子の創製2023
- Author(s)
  金子信人、久保田大貴、姫野美沙緒、木戸丈友、宮島　篤、大栗博毅
- Organizer
  日本化学会
- Data Source
  KAKENHI-PROJECT-20K17042
[Presentation] B型肝炎ウイルス複製阻害活性を示すマイケルアクセプター含有アルカロイド類似化合物の同定2023
- Author(s)
  姫野美沙緒、金子信人、久保田大貴、木戸丈友、宮島篤、杉山真也、モイメンリン、大栗博毅
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K17042
[Presentation] B型肝炎ウイルスの感染・複製を阻害するアルカロイド類似化合物の探索2021
- Author(s)
  姫野美沙緒、木戸丈友、久保田大貴、大栗博毅、宮島篤
- Organizer
  肝細胞研究会
- Data Source
  KAKENHI-PROJECT-18K15773
[Presentation] B型肝炎ウイルスの感染・複製を阻害するアルカロイド類似化合物の探索2021
- Author(s)
  姫野美沙緒、木戸丈友、久保田大貴、大栗博毅、宮島篤
- Organizer
  第28回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-20K17042
[Presentation] Modulation of Hepatitis B virus Infection by Epidermal Growth Factor2020
- Author(s)
  Shin-Wei Chen, Misao Himeno, Yuta Koui, Masaya Sugiyama, Hironori Nishitsuji, Masashi Mizokami, Kunitada Shimotohno, Atsushi Miyajima and Taketomo Kido
- Organizer
  第27回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-20K17042
[Presentation] Modulation of Hepatitis B virus Infection by Epidermal Growth Factor.2020
- Author(s)
  Shin-Wei Chen, Misao Himeno, Yuta Koui, Masaya Sugiyama, Hironori Nishitsuji, Masashi Mizokami, Kunitada Shimotohno, Atsushi Miyajima, Taketomo Kido
- Organizer
  第27回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-18K15773
[Presentation] 星細胞と肝細胞の三次元共培養モデルによるB型肝炎ウイルス感染系の確立2019
- Author(s)
  姫野美沙緒、厚井悠太、陳欣蔚、西辻裕紀、杉山真也、溝上雅史、木戸丈友、宮島篤
- Organizer
  第67回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-18K15773
[Presentation] ヒトiPS細胞由来静止期星細胞の樹立とその活性化制御2019
- Author(s)
  厚井悠太、大山裕棋、CHEN Shin-Wei、姫野（黒木）美沙緒、宮島篤、木戸丈友
- Organizer
  第18回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K15773
[Presentation] ヒトiPS細胞由来肝星細胞の活性化制御2018
- Author(s)
  厚井悠太、木戸丈友、大山裕棋、Shin-Wei CHEN、姫野（黒木）美沙緒、宮島篤
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K15773
[Presentation] GENERATION OF HUMAN LIVER TISSUE WITH FUNCTIONAL BILIARY STRUCTURE2018
- Author(s)
  Hiroki Oyama, Taketomo Kido, Yuta Koui, Shin-Wei Chen, Misao Himeno, Atsushi Miyajima
- Organizer
  ISSCR annual meeting 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15773
[Presentation] 機能的胆管様構造の導入による肝組織の構築2018
- Author(s)
  大山裕棋、木戸丈友、厚井悠太、Shin-Wei Chen、姫野美沙緒、宮島篤
- Organizer
  第17回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-18K15773
[Presentation] 肝スフェロイドの積層による胆管ネットワークを備えた肝組織の構築2018
- Author(s)
  大山裕棋、厚井悠太、チェンシンウェイ、姫野（黒木）美沙緒、國富芳博、高井治美、宮島篤、木戸丈友
- Organizer
  第25回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-18K15773
[Presentation] 肝構成細胞の共培養によるin vitro肝モデルの構築2018
- Author(s)
  厚井悠太、大山裕棋、チェンシンウェイ、姫野（黒木）美沙緒、宮島篤、木戸丈友
- Organizer
  第25回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-18K15773

1. モイメンリン (40597499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 亀谷美恵 (50338787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 谷口怜 (60734465)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 馬島龍一 (90990060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 中野泰博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Himeno Misao 姫野 美沙緒

Research Projects

Research Products

Co-Researchers

Determination of T-B cell epitope for the development of novel anti-flavivirus therapeutic antibodies and contribution to a better understanding of pathogenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction and application of hepatitis B virus reporter system using fluorescence-activating proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of three dimensional HBV infection model which reflects the pathological progressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] iPS細胞から肝類洞壁細胞への分化誘導法2021

Author(s)

Total Pages

Publisher

Data Source

[Book] iPS細胞から肝類洞壁細胞への分化誘導法2021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Utility of an In-Vitro Micro-Neutralizing Test in Comparison to a Plaque Reduction Neutralization Test for Dengue Virus, Japanese Encephalitis Virus, and Zika Virus Serology and Drug Screening2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Co-culture Model for Hepatitis B Virus Infection Using iPSC-Derived Liver Progenitor Cells and Liver Sinusoidal Endothelial Cells2022

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Development of human iPSC-derived quiescent hepatic stellate cell-like cells for drug discovery and in vitro disease modeling2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modulation of hepatitis B virus infection by epidermal growth factor secreted from liver sinusoidal endothelial cells2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] Development of anti-HBV agents that contain alkaloidal scaffolds bearing Michael acceptors2024

Author(s)

Organizer

Data Source

[Presentation] マイケルアクセプターを有するアルカロイド類似化合物群の骨格多様化合成による抗B型肝炎ウイルス活性分子の創製2023

Author(s)

Organizer

Data Source

[Presentation] B型肝炎ウイルス複製阻害活性を示すマイケルアクセプター含有アルカロイド類似化合物の同定2023

Author(s)

Organizer

Data Source

[Presentation] B型肝炎ウイルスの感染・複製を阻害するアルカロイド類似化合物の探索2021

Author(s)

Organizer

Data Source

[Presentation] B型肝炎ウイルスの感染・複製を阻害するアルカロイド類似化合物の探索2021

Author(s)

Organizer

Data Source

[Presentation] Modulation of Hepatitis B virus Infection by Epidermal Growth Factor2020

Author(s)

Organizer

Data Source

[Presentation] Modulation of Hepatitis B virus Infection by Epidermal Growth Factor.2020

Author(s)

Organizer

Himeno Misao 姫野美沙緒