KUSE NOZOMI 久世望

… Alternative Names

Kuse Nozomi 久世望

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Researcher Number	80710409
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所エイズ研究センター, 主任研究員 2025: 国立健康危機管理研究機構, 国立感染症研究所ワクチン開発研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2025: 国立健康危機管理研究機構, エイズ研究センター, 主任研究官 2022: 国立感染症研究所, 治療薬・ワクチン開発研究センター, 主任研究官 2020 – 2021: 熊本大学, ヒトレトロウイルス学共同研究センター, 特任講師 2016 – 2017: 熊本大学, エイズ学研究センター, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related / Basic Section 49070:Immunology-related / Immunology
Keywords	Principal Investigator HLA / HIV-1 / エピトープ / 細胞傷害性T細胞 / プライミング / CD8陽性T細胞 / CTL / TCR / CD8 / 変異ウイルス … More / cART / メモリー / ナイーブ / 変異 / protective epitope / naive / STING / priming / mutant / 逃避変異体 / 免疫学 / HIV / TLRリガンド / エフェクター分子 / STINGリガンド / ナイーブT細胞 Less

HIV-1完治に向けた疲弊メモリーCD8陽性T細胞の新規機能回復法の開発Principal Investigator
- Principal Investigator
  
  久世望
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Japan Institute for Health Security
Development of a novel approach to induce cellular immune response for elimination of circulating HIV-1Principal Investigator
- Principal Investigator
  
  Kuse Nozomi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  National Institute of Infectious Diseases
  Kumamoto University
Mechanism of induction of high-functional HIV-1-specific CD8 T cells from naive T cellsPrincipal Investigator
- Principal Investigator
  
  KUSE NOZOMI
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Kumamoto University

All 2023 2022 2021 2020 2018 2017 2016

All Journal Article Presentation

[Journal Article] Control of HIV-1 Replication by CD8+ T Cells Specific for Two Novel Pol Protective Epitopes in HIV-1 Subtype A/E Infection.2022
- Author(s)
  Nguyen HT, Kuse N, Zhang Y, Murakoshi H, Maeda Y, Tamura Y, Maruyama R, Tran GV, Nguyen TV, Nguyen KV, Oka S, Chikata T, Takiguchi M.
- Journal Title
  
  Journal of Virology
  
  Volume: 96 Issue: 19
- DOI
  10.1128/jvi.00811-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08602, KAKENHI-PROJECT-19K08932, KAKENHI-PROJECT-20K07549
[Journal Article] Impact of Micropolymorphism Outside the Peptide Binding Groove in the Clinically Relevant Allele HLA-C*14 on T Cell Responses in HIV-1 Infection2022
- Author(s)
  Chikata T, Paes W, Kuse N, Partridge T, Gatanaga H, Zhang Y, Kuroki K, Maenaka K, Ternette N, Oka S, Borrow P, Takiguchi M
- Journal Title
  
  Journal of Virology
  
  Volume: 96 Issue: 10
- DOI
  10.1128/jvi.00432-22
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549
[Journal Article] Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele2022
- Author(s)
  Zhang Yu、Chikata Takayuki、Kuse Nozomi、Murakoshi Hayato、Gatanaga Hiroyuki、Oka Shinichi、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 96 Issue: 22
- DOI
  10.1128/jvi.01248-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03726, KAKENHI-PROJECT-20K07549
[Journal Article] STING Ligand-Mediated Priming of Functional CD8+ T Cells Specific for HIV-1-Protective Epitopes from Naive T Cells2021
- Author(s)
  Kuse Nozomi、Akahoshi Tomohiro、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 16
- DOI
  10.1128/jvi.00699-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03726, KAKENHI-PROJECT-20K07549
[Journal Article] Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-12020
- Author(s)
  Zhang Yu、Kuse Nozomi、Akahoshi Tomohiro、Chikata Takayuki、Gatanaga Hiroyuki、Oka Shinichi、Murakoshi Hayato、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 94 Issue: 19
- DOI
  10.1128/jvi.01151-20
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549, KAKENHI-PROJECT-20H03726
[Journal Article] T-cell responses to sequentially emerging viral escape mutants shape long-term HIV-1 population dynamics2020
- Author(s)
  Akahoshi Tomohiro、Gatanaga Hiroyuki、Kuse Nozomi、Chikata Takayuki、Koyanagi Madoka、Ishizuka Naoki、Brumme Chanson J.、Murakoshi Hayato、Brumme Zabrina L.、Oka Shinichi、Takiguchi Masafumi
- Journal Title
  
  PLOS Pathogens
  
  Volume: 16 Issue: 12 Pages: e1009177-e1009177
- DOI
  10.1371/journal.ppat.1009177
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549
[Journal Article] Critical effect of Pol escape mutations associated with detrimental allele HLA-C?15:05 on clinical outcome in HIV-1 subtype A/E infection2020
- Author(s)
  Murakoshi Hayato、Chikata Takayuki、Akahoshi Tomohiro、Zou Chengcheng、Borghan Mohamed Ali、Van Tran Giang、Nguyen Trung Vu、Van Nguyen Kinh、Kuse Nozomi、Takiguchi Masafumi
- Journal Title
  
  AIDS
  
  Volume: 35 Issue: 1 Pages: 33-43
- DOI
  10.1097/qad.0000000000002704
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549
[Journal Article] The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro2020
- Author(s)
  Papagno Laura、Kuse Nozomi、Lissina Anna、Gostick Emma、Price David A.、Appay Victor、Nicoli Francesco
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 11620-11620
- DOI
  10.1038/s41598-020-67704-0
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549
[Journal Article] Effect of Difference in Consensus Sequence between HIV-1 Subtype A/E and Subtype B Viruses on Elicitation of Gag-Specific CD8+ T Cells and Accumulation of HLA-Associated Escape Mutations2020
- Author(s)
  Zhang Yu、Murakoshi Hayato、Chikata Takayuki、Akahoshi Tomohiro、Tran Giang Van、Nguyen Trung Vu、Gatanaga Hiroyuki、Nguyen Kinh Van、Oka Shinichi、Kuse Nozomi、Takiguchi Masafumi
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 6
- DOI
  10.1128/jvi.02061-20
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549
[Journal Article] Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.2017
- Author(s)
  Murakoshi H, Koyanagi M, Chikata T, Rahman MA, Kuse N, Sakai K, Gatanaga H, Oka S, Takiguchi M.
- Journal Title
  
  J Virol.
  
  Volume: 91(4) Issue: 4
- DOI
  10.1128/jvi.02082-16
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240, KAKENHI-PROJECT-15K19588, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19614
[Journal Article] HLA Class I-Mediated HIV-1 Control in Vietnamese Infected with HIV-1 Subtype A/E2017
- Author(s)
  Chikata Takayuki、Tran Giang Van、Murakoshi Hayato、Akahoshi Tomohiro、Qi Ying、Naranbhai Vivek、Kuse Nozomi、Tamura Yoshiko、Koyanagi Madoka、Sakai Sachiko、et al.
- Journal Title
  
  Journal of Virology
  
  Volume: 92 Issue: 5
- DOI
  10.1128/jvi.01749-17
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08129, KAKENHI-PROJECT-17K10021, KAKENHI-PROJECT-15H02658, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19160, KAKENHI-PROJECT-16K19614
[Journal Article] HIV-1 control by NK cells via reduced interaction between KIR2DL2 and HLA-C*12:02/C*14:032016
- Author(s)
  Lin Z, Kuroki K, Kuse N, Sun X, Akahoshi T, Qi Y, Chikata T, Naruto T, Koyanagi M, Murakoshi H, Gatanaga H, Oka S, Carrington M, Maenaka K, Takiguchi M.
- Journal Title
  
  Cell Rep.
  
  Volume: 17 (9) Issue: 9 Pages: 2210-2220
- DOI
  10.1016/j.celrep.2016.10.075
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19160
[Journal Article] Effects of a Single Escape Mutation on T Cell and HIV-1 Co-adaptation.2016
- Author(s)
  Sun X, Shi Y, Akahoshi T, Fujiwara M, Gatanaga H, Schönbach C, Kuse N, Appay V, Gao GF, Oka S, Takiguchi M.
- Journal Title
  
  Cell Rep.
  
  Volume: 15 (10） Issue: 10 Pages: 2279-91
- DOI
  10.1016/j.celrep.2016.05.017
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293240, KAKENHI-PROJECT-16K19159, KAKENHI-PROJECT-16K19160
[Presentation] Effective priming of functional CD8+ T cells specific for HIV protective epitopes from naïve T cells2023
- Author(s)
  Nozomi Kuse
- Organizer
  Oxford-Kumamoto Universities Joint Annual Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549
[Presentation] Functional CD8+ T cells specific for HIV-1 protective epitopes primed with STING ligand2021
- Author(s)
  Nozomi Kuse, Tomohiro Akahoshi, and Masafumi Takiguchi
- Organizer
  The 35th Annual Meeting of the Japanese Society for AIDS Research France-Japan Joint Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07549
[Presentation] ナイーブT細胞からのconserved/プロテクティブエピトープ特異的CTLの誘導2020
- Author(s)
  久世望, 赤星智寛, 滝口雅文
- Organizer
  第34回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-20K07549
[Presentation] Control of HIV-1 by CD8+ T cells specific for Gag epitopes in conserved-region mosaic vaccine2018
- Author(s)
  Chengcheng Zou, Hayato Murakoshi, Nozomi Kuse, Hiroyuki Gatanaga, Shinichi Oka, Tomas Hanke, and Masafumi Takiguchi
- Organizer
  Keystone Symposia: Progress and Pathways Toward an Effective HIV Vaccine (J6)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] HLA class I-mediated HIV-1 control in Vietnamese infected with HIV-1 subtype A/E2018
- Author(s)
  Masafumi Takiguchi, Takayuki Chikata, Giang Van Tran, Hayato Murakoshi, Tomohiro Akahoshi, Ying Qi, Vivek Naranbhai, Nozomi Kuse, Yoshiko Tamura, Madoka Koyanagi, Sachiko Sakai, Dung Hoai Nguyen, Dung Thi Nguyen, Ha Thu Nguyen, Trung Vu Nguyen, Shinichi Oka et al.
- Organizer
  20th International Conference on Emerging Infectious Diseases in the Pacific Rim /U.S.-Japan Cooperative Medical Sciences Program:AIDS and Immunology Joint Panel
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] HLA class I-mediated HIV-1 control in HIV-1 infection2018
- Author(s)
  Masafumi Takiguchi, Hayato Murakoshi, Takayuki Chikata, Tomohiro Akahoshi, Nozomi Kuse, Zhansong Lin, Mary Carrington, Hiroyuki Gatanaga, and Shinichi Oka
- Organizer
  20th International Conference on Emerging Infectious Diseases in the Pacific Rim/U.S.-Japan Cooperative Medical Sciences Program
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Effective priming of CD8+ T cells with ability to suppress HIV-1 replication using STING ligand2017
- Author(s)
  Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Ken J. Ishii, Takuya Yamamoto, Victor Appay, and Masafumi Takiguchi
- Organizer
  IAS 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] 強いHIV-1増殖抑制能を有したCTLによる変異HIV-1の認識2017
- Author(s)
  村越勇人, 久世望, 赤星智寛, 近田貴敬, Zhang Yu, 潟永博之, 岡　慎一, 滝口雅文
- Organizer
  第31回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] ベトナム人HIV-1サブタイプA/E感染者コホートにおける、エイズ病態進行に関与するHLAアリルおよびHLA関連HIV-1多型のエイズ病態進行に及ぼす影響2017
- Author(s)
  近田貴敬, Tran Van Giang, 村越勇人, 田村美子, 赤星智寛, 久世望, 阪井恵子, 小柳円, Kinh Van Nguyen, 滝口雅文
- Organizer
  第31回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] 複数の異なったHLA拘束性CTLによるRT135変異の選択とその相互作用2017
- Author(s)
  赤星智寛, 久世望, 村越勇人, 近田貴敬, 潟永博之, 岡慎一, 滝口雅文
- Organizer
  第31回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Impact of a single escape mutation selected by HLA-A*24:02-restricted CD8+ T cells on HIV-1 control by HLA-B*35:01-restricted ones and T cell adaptation2017
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Katherine L James, Yoshiko Tamura, Nozomi Kuse, Xiaoming Sun, Hiroyuki Gatanaga, Sarah L Rowland-Jones,　Shinichi Oka, and Masafumi Takiguchi
- Organizer
  IAS 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] STING ligand effectively prime functional HIV-1-specific CD8+ T Cells from naive T cells2017
- Author(s)
  Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Takuya Yamamoto, Victor Appay, and Masafumi Takiguchi
- Organizer
  18th Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Impact of a single escape mutation selected by HLA-A*24:02-restricted CD8+ T cells on HIV-1 control by HLA-B*35:01-restricted ones and T cell adaptation2017
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Nozomi Kuse, and Masafumi Takiguchi
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Control of HIV-1 by CD8+ T cells recognizing Gag conserved region2017
- Author(s)
  Chengcheng Zou, Hayato Murakoshi, Nozomi Kuse, Hiroyuki Gatanaga, Shinichi Oka, Tomas Hanke, and Masafumi Takiguchi
- Organizer
  18th Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] STINGリガンドによるウイルス抑制機能の高いHIV-1特異的CD8陽性T細胞のプライミング2017
- Author(s)
  久世望, Sun Xiaoming, 赤星智寛, Lissina Anna, 山本拓也, Appay Victor, 滝口雅文
- Organizer
  第31回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] The Effect of KIR Genes on HIV-1 Control in the Vietnamese Cohort2017
- Author(s)
  Zhansong Lin, Takayuki Chikata, Giang Van Tran, Hayato Murakoshi, Tomohiro Akahoshi, Nozomi Kuse, Yoshiko Tamura, Madoka Koyanagi, Sachiko Sakai, Dung Hoai Nguyen, Dung Thi Nguyen, Ha Thu Nguyen, Trung Vu Nguyen, Keiko Sakai, Kinh Van Nguyen, and Masafumi Takiguchi
- Organizer
  18th Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Generation of HIV-1 polymorphism at RT135 via coevolution of multiple HIV-1-specific T cells with HIV-12017
- Author(s)
  Tomohiro Akahoshi, Nozomi Kuse, Hayato Murakoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Organizer
  18th Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] HLA class I-mediated HIV-1 control in Vietnamese infected with HIV-1 subtype A/E2017
- Author(s)
  Takayuki Chikata, Giang Van Tran, Hayato Murakoshi, Tomohiro Akahoshi, Nozomi Kuse, Ying Qi, Yoshiko Tamura, Madoka Koyanagi, Sachiko Sakai, Dung Hoai Nguyen, Dung Thi Nguyen, Ha Thu Nguyen, Trung Vu Nguyen, Shinichi Oka, Marry Carrington, Keiko Sakai, Kinh Van Nguyen, and Masafumi Takiguchi
- Organizer
  18th Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Effective priming of functional HIV-1-specific CD8+ T Cells from naive T cells using STING ligand2017
- Author(s)
  Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Takuya Yamamoto, Victor Appay, and Masafumi Takiguchi,
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Analysis of conserved epitopes-specific and cross-reactive CTLs controlling HIV-1 in Japanese individuals2017
- Author(s)
  Yu Zhang, Nozomi Kuse, Hayato Murakoshi, Tomohiro Akahoshi, Takayuki Chikata, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Organizer
  18th Kumamoto AIDS Seminar
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Identification of a detrimental HLA haplotype and the effect of its associated HIV-1 mutations in HIV-1 subtype A/E-infected Vietnamese2017
- Author(s)
  Takayuki Chikata, Hayato Murakoshi, Tomohiro Akahoshi, Nozomi Kuse, Yoshiko Tamura, Keiko Sakai, and Masafumi Takiguchi
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] ベトナム人HIV-1サブタイプA/E感染者コホートにおけるエイズ病態進行に関与するHLAアリルの探索2016
- Author(s)
  近田貴敬, Giang Van Tran, 村越勇人, 田村美子, 赤星智寛, 久世望, 阪井恵子, 小柳円, Kinh Van Nguyen, 滝口雅文
- Organizer
  第30回日本エイズ学会学術集会・総会
- Place of Presentation
  鹿児島
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] In vitro priming of HIV-1-specific CD8+ T cells from naive T cells.2016
- Author(s)
  Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Takuya Yamamoto, Ken J. Ishii, Victor Appay, and Masafumi Takiguchi
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄・宜野湾
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Contribution of HLA class I alleles to clinical outcome in HIV-1 subtype A/E infected Vietnamese individuals.2016
- Author(s)
  Takayuki Chikata, Giang Van Tran, Hayato Murakoshi, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Keiko Sakai, Kinh Van Nguyen, and Masafumi Takiguchi
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Impact of a Single HLA-A*24:02-associated Escape Mutation on HLA-B*35:01-associated HIV-1 Control and T cell Adaptation.2016
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Katherine L James, Yoshiko Tamura, Nozomi Kuse, Xiaoming Sun, Hiroyuki Gatanaga, Sarah L Rowland-Jones,　Shinichi Oka, and Masafumi Takiguchi
- Organizer
  第30回日本エイズ学会学術集会・総会
- Place of Presentation
  鹿児島
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Contribution of HLA class I alleles to clinical outcome in HIV-1 subtype A/E infected Vietnamese individuals.2016
- Author(s)
  Takayuki Chikata, Giang Van Tran, Hayato Murakoshi, Yoshiko Tamura, Tomohiro Akahoshi, Nozomi Kuse, Madoka Koyanagi, Sachiko Sakai, Keiko Sakai, Kinh Van Nguyen, and Masafumi Takiguchi
- Organizer
  2nd Kumamoto IRCMS International Symposium and 17th Kumamoto AIDS Seminar
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Control of HIV-1 by NK cells via KIR-2DL2 and 2 HLA-C allele.2016
- Author(s)
  Zhansong Lin, Kimiko Kuroki, Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Ying Qi, Takayuki Chikata, Takuya Naruto, Madoka Koyanagi, Hayato Murakoshi, Hiroyuki Gatanaga, Shinichi Oka, Mary Carrington, Katsumi Maenaka, and Masafumi Takiguchi
- Organizer
  2nd Kumamoto IRCMS International Symposium and 17th Kumamoto AIDS Seminar
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] The effect of a single CTL escape -mutation on HIV-1 control by NK cell functions.2016
- Author(s)
  Zhansong Lin, Nozomi Kuse, Tomohiro Akahoshi, Kimiko Kuroki, Katsumi Maenaka, and Masafumi Takiguchi
- Organizer
  第30回日本エイズ学会学術集会・総会
- Place of Presentation
  鹿児島
- Year and Date
  2016-11-24
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] The effect of one amino acid difference outside of peptide binding groove of HLA-C molecules on NK cell function and HIV-1 control.2016
- Author(s)
  Zhansong Lin, Nozomi Kuse, Tomohiro Akahoshi, Kimiko Kuroki, Katsumi Maenaka, and Masafumi Takiguchi
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄・宜野湾
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Co-evolution between HIV-1 escape mutant and HIV-1-specific T cells.2016
- Author(s)
  Tomohiro Akahoshi, Masao Hashimoto, Takayuki Chikata, Hayato Murakoshi, Nozomi Kuse, Yoshiko Tamura, Hiroyuki Gatanaga, Shinichi Oka, and Masafumi Takiguchi
- Organizer
  2nd Kumamoto IRCMS International Symposium and 17th Kumamoto AIDS Seminar
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Functional analysis of HIV-1-specific CD8+ T cells primed in vitro from naive T cells.2016
- Author(s)
  Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Victor Appay, and Masafumi Takiguchi
- Organizer
  2nd Kumamoto IRCMS International Symposium and 17th Kumamoto AIDS Seminar
- Place of Presentation
  Kumamoto, Japan
- Year and Date
  2016-10-31
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] In Vitro Priming of HIV-1-specific CD8+ T Cells from Naive T Cells.2016
- Author(s)
  Nozomi Kuse, Xiaoming Sun, Tomohiro Akahoshi, Anna Lissina, Victor Appay, and Masafumi Takiguchi
- Organizer
  HIVR4P 2016
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159
[Presentation] Impaired Effect of HLA-A*24:02-Associated Mutation on HLA-B*35:01-Associated HIV-1 Control.2016
- Author(s)
  Hayato Murakoshi, Tomohiro Akahoshi, Madoka Koyanagi, Takayuki Chikata, Katherine L James, Nozomi Kuse, Yoshiko Tamura, Sarah L Rowland-Jones, Shinichi Oka, Hiroyuki Gatanaga, and Masafumi Takiguchi
- Organizer
  HIVR4P 2016
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19159

1. MURAKOSHI Hayato

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
2. AKAHOSHI Tomohiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
3. CHIKATA Takayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
4. 滝口雅文

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
5. 岡慎一

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
6. 小柳円

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 前田洋助

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KUSE NOZOMI 久世 望

Kuse Nozomi 久世 望

Research Projects

Research Products

Co-Researchers

HIV-1完治に向けた疲弊メモリーCD8陽性T細胞の新規機能回復法の開発Principal Investigator

Principal Investigator

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Development of a novel approach to induce cellular immune response for elimination of circulating HIV-1Principal Investigator

Principal Investigator

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Review Section

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Mechanism of induction of high-functional HIV-1-specific CD8 T cells from naive T cellsPrincipal Investigator

Principal Investigator

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[Journal Article] Control of HIV-1 Replication by CD8+ T Cells Specific for Two Novel Pol Protective Epitopes in HIV-1 Subtype A/E Infection.2022

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[Journal Article] Impact of Micropolymorphism Outside the Peptide Binding Groove in the Clinically Relevant Allele HLA-C*14 on T Cell Responses in HIV-1 Infection2022

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[Journal Article] Immunological Control of HIV-1 Disease Progression by Rare Protective HLA Allele2022

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[Journal Article] STING Ligand-Mediated Priming of Functional CD8+ T Cells Specific for HIV-1-Protective Epitopes from Naive T Cells2021

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[Journal Article] Role of Escape Mutant-Specific T Cells in Suppression of HIV-1 Replication and Coevolution with HIV-12020

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[Journal Article] T-cell responses to sequentially emerging viral escape mutants shape long-term HIV-1 population dynamics2020

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[Journal Article] Critical effect of Pol escape mutations associated with detrimental allele HLA-C?15:05 on clinical outcome in HIV-1 subtype A/E infection2020

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[Journal Article] The TLR9 ligand CpG ODN 2006 is a poor adjuvant for the induction of de novo CD8+ T-cell responses in vitro2020

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[Journal Article] Effect of Difference in Consensus Sequence between HIV-1 Subtype A/E and Subtype B Viruses on Elicitation of Gag-Specific CD8+ T Cells and Accumulation of HLA-Associated Escape Mutations2020

Author(s)

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[Journal Article] Accumulation of Pol Mutations Selected by HLA-B*52:01-C*12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.2017

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[Journal Article] HLA Class I-Mediated HIV-1 Control in Vietnamese Infected with HIV-1 Subtype A/E2017

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Data Source

[Journal Article] HIV-1 control by NK cells via reduced interaction between KIR2DL2 and HLA-C*12:02/C*14:032016

Author(s)

KUSE NOZOMI 久世望

Kuse Nozomi 久世望

[Journal Article] Accumulation of Pol Mutations Selected by HLA-B52:01-C12:02 Protective Haplotype-Restricted Cytotoxic T Lymphocytes Causes Low Plasma Viral Load Due to Low Viral Fitness of Mutant Viruses.2017

[Journal Article] HIV-1 control by NK cells via reduced interaction between KIR2DL2 and HLA-C12:02/C14:032016

[Presentation] Effective priming of functional CD8+ T cells specific for HIV protective epitopes from naïve T cells2023

[Presentation] Impact of a single escape mutation selected by HLA-A24:02-restricted CD8+ T cells on HIV-1 control by HLA-B35:01-restricted ones and T cell adaptation2017

[Presentation] Impact of a single escape mutation selected by HLA-A24:02-restricted CD8+ T cells on HIV-1 control by HLA-B35:01-restricted ones and T cell adaptation2017