Ariyama Hiroshi 有山寛

… Alternative Names

ARIYAMA Hiroshi 有山寛

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Researcher Number	80713437
Affiliation (Current)	2025: 九州大学, 医学研究院, 共同研究員
Affiliation (based on the past Project Information) *help	2023: 九州大学, 医学研究院, 共同研究員 2015 – 2022: 九州大学, 大学病院, 助教 2015: 九州大学病院, 血液・腫瘍内科, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 50010:Tumor biology-related Except Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related
Keywords	Principal Investigator 胃組織幹細胞 / オルガノイド / 腸型胃がん / BMPシグナル / 腸上皮化生 / 萎縮性胃炎 / RUNX / SMAD4 / p21 / atrophic gastritis … More / RUNX3 / LATS2 / WNT / LGR5 / BMP / intestinal metaplasia / 印環細胞癌 / MMP / 印環細胞 / E-カドヘリン / MMP3 / CXCR4 / E-cadherin / 胃印環細胞がん … More Except Principal Investigator 消化器癌 / 胃癌 / リンパ球 / 消化器腫瘍 / CD4陽性T細胞 / 腫瘍浸潤リンパ球 / イメージングマスサイトメトリー / 腫瘍微小環境 / 免疫チェックポイント阻害 / 疲弊T細胞 / 三次リンパ組織様構造 / 腫瘍免疫 / 末梢血循環がん細胞 / 消化管がん / がんの単細胞遺伝子解析 / 腹腔内マクロファージ / がん性腹水 / TGFβ / TGF-β / がん幹細胞 / 単細胞解析 / 大腸がん / スフェア / 印環細胞癌 / 上皮間葉転換 / オルガノイド / 組織幹細胞 / 癌幹細胞 / 大腸癌 Less

Establishment of carcinogenesis model of intestinal type gastric cancer from the organoid of atrophic gastritis patient.Principal Investigator
- Principal Investigator
  
  Ariyama Hiroshi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyushu University
Treatment resistance based on the cellular components of tertiary lymphoid structure in gastrointestinal cancers
- Principal Investigator
  
  Baba Eishi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyushu University
Establishment of in vitro human gastric signet-ring carcinogenesis model.Principal Investigator
- Principal Investigator
  
  Ariyama Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Kyushu University
Molecular mechanisms of differentiation and metastasis of human gastrointestinal cancer stem cells
- Principal Investigator
  
  Baba Eishi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Analysis of drug sensitivity and resistance by single cell-based genetic assay and intratumoral profiling of gastric cancer
- Principal Investigator
  
  Arita Shuji
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University

All 2022 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions2022
- Author(s)
  Ito Mamoru、Nakano Michitaka、Ariyama Hiroshi、Yamaguchi Kyoko、Tanaka Risa、Semba Yuichiro、Sugio Takeshi、Miyawaki Kohta、Kikushige Yoshikane、Mizuno Shinichi、Isobe Taichi、Tanoue Kenro、Taguchi Ryosuke、Ueno Shohei、Kawano Takahito、Murata Masaharu、Baba Eishi、Akashi Koichi
- Journal Title
  
  Cancer Letters
  
  Volume: 532 Pages: 215597-215597
- DOI
  10.1016/j.canlet.2022.215597
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21617, KAKENHI-PROJECT-19H03687, KAKENHI-PROJECT-20J00897, KAKENHI-PROJECT-20K08311, KAKENHI-PROJECT-21K07152, KAKENHI-PROJECT-21K12685, KAKENHI-PROJECT-21K18325, KAKENHI-PROJECT-21H04827, KAKENHI-PROJECT-23K24364, KAKENHI-PROJECT-23K25209, KAKENHI-PROJECT-19K16852, KAKENHI-PROJECT-20K17403
[Journal Article] Colorectal cancer stem cell population consist of heterogeneous cells based on E-cadherin expression with different tumorigenic potential in vivo2018
- Author(s)
  Tamura S, Isobe T, Ariyama H, Nakano M, Kikushige Y, Takaishi S, Kusaba H, Takenaka K, Ueki T, Nakamura M, Akashi K, Baba E
- Journal Title
  
  Oncol Rep
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08970
[Journal Article] Efficacy and safety analysis of oxaliplatin-based chemotherapy for advanced gastric cancer with a prior treatment of cisplatin2017
- Author(s)
  Inadomi K, Kusaba H, Matsushita Y, Tanaka R, Mitsugi K, Arimizu K, Hirano G, Makiyama A, Ohmura H, Uchino K, Hanamura F, Shibata Y, Kuwayama M, Esaki T, Takayoshi K, Arita S, Ariyama H, Akashi K, Baba E
- Journal Title
  
  Anticancer Res
  
  Volume: 7 Pages: 2663-2671
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08970
[Journal Article] Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer2017
- Author(s)
  Makiyama A, Arimizu K, Hirano G, Makiyama C, Matsushita Y, Shirakawa T, Ohmura H, Komoda M, Uchino K, Inadomi K, Arita S, Ariyama H, Kusaba H, Shinohara Y, Kuwayama M, Kajitani T, Oda H, Esaki T, Akashi K, Baba E
- Journal Title
  
  Gastric Cancer
  
  Volume: - Issue: 3 Pages: 464-472
- DOI
  10.1007/s10120-017-0759-9
- NAID
  40021539459
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] Circulating "stem-like" PD-1+ CD8 T cells respond to PD-1 blockade and predict clinical outcomes in esophageal cancer2022
- Author(s)
  Tanoue S, Ohmura H, Tsuchihashi K, Shinohara Y, Ito M, Yamaguchi K, Tamura S, Shimokawa H, Isobe T, Shibata Y, Ariyama H, Tanaka R, Kusaba H, Esaki T, Mitsugi K, Akashi K, Baba E
- Organizer
  第19回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20K08311
[Presentation] The risk factors for oxaliplatin-induced thrombocytopenia and neuropathy in advanced gastric cancer2017
- Author(s)
  Kyoko Inadomi, Hitoshi Kusaba, Akitaka Makiyama, Kenji Mitsugi, Keita Uchino, Shingo Tamura, Yoshihiro Shibata, Taito Esaki, Kenji Tsuchihashi, Shuji Arita, Hiroshi Ariyama, Eishi Baba
- Organizer
  第90回日本胃癌学会総会
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] マウス胃組織幹細胞の同定および印環細胞癌発癌マウスモデルの構築2017
- Author(s)
  有山寛、早河翼、馬場英司、赤司浩一、Timothy C. Wang
- Organizer
  第89回日本胃癌学会総会
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] 胃組織幹細胞と印環細胞癌発癌モデルマウス2017
- Author(s)
  有山寛、早河翼、馬場英司、赤司浩一、Timothy C. Wang
- Organizer
  第27回日本サイトメトリー学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] 胃印環細胞癌における癌幹細胞とニッチ2017
- Author(s)
  有山寛、早河翼、馬場英司、赤司浩一、Timothy C. Wang
- Organizer
  胃印環細胞癌における癌幹細胞とニッチ
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] 癌性腹水中TILは疲弊マーカーを高頻度で発現する2017
- Author(s)
  中野倫孝、伊東守、田中吏佐、稲富享子、三ツ木健二、土橋賢司、有山寛、草場仁志、赤司浩一、馬場英司
- Organizer
  第15回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] TGF-beta regulates CD44 expression of cancer cells through epithelial-to-mesenchymal transition in malignant ascites2016
- Author(s)
  Michitaka Nakano, Hiroshi Ariyama, Eishi Baba, et al.
- Organizer
  第14回日本臨床腫瘍学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] TGF-beta signaling pathway induced cancer stem-like properties in human CD44- colorectal cancer cells2016
- Author(s)
  Michitaka Nakano, Mamoru Tanaka, Taichi Isobe, Yasufumi Uehara, Kohta Miyawaki, Yoshikane Kikushige, Shinichi Mizuno, Kenji Tsuchihashi, Shuji Arita, Hiroshi Ariyama, Hitoshi Kusaba, Takashi Ueki, Koichi Akashi and Eishi Baba
- Organizer
  AACR annual meeting 2016
- Place of Presentation
  New Orleans
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860542
[Presentation] Transition of macrophage to fibroblast promote cancer progression in malignant ascites environment within gastrointestinal peritoneal carcinomatosis patients.2016
- Author(s)
  Mamoru Ito, Hiroshi Ariyama, Eishi Baba, et al.
- Organizer
  AACR2016
- Place of Presentation
  New Orleans, USA
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] Macrophage to fibroblast transition promote cancer progression in malignant ascitic environment within gastrointestinal peritoneal carcinomatosis patients2016
- Author(s)
  Mamoru Tanaka, Michitaka Nakano, Hiroshi Ariyama, Risa Tanaka, Shigeo Takaishi, Eishi Baba and Koichi Akashi
- Organizer
  AACR annual meeting 2016
- Place of Presentation
  New Orleans
- Year and Date
  2016-04-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860542
[Presentation] Placiticity of CD44+ colorectal cancer stem cells depend on TGF-beta-induced epithelial mesenchymal transition：evidences from an ex vivo culturePlaciticity of CD44+ colorectal cancer stem cells depend on TGF-beta-induced epithelial mesenchymal transition：evidences from an ex vivo culture2015
- Author(s)
  Michitaka Nakano, Hiroshi Ariyama, Shingo Tamura, Taichi Isobe, Kohta Miyawaki, Hitoshi Kusaba, Takashi Ueki, Eishi Baba, Koichi Akashi
- Organizer
  AACR
- Place of Presentation
  Philadelphia
- Year and Date
  2015-04-20
- Data Source
  KAKENHI-PROJECT-25860542
[Presentation] Plasticity of CD44+ colorectal cancer cell depends on TGF-beta induced EMT2015
- Author(s)
  Michitaka Nakano, Hiroshi Ariyama, Shingo Tamura, Taichi Isobe, Kohta Miyawaki, Yuta Okumura, Hitoshi Kusaba, Takashi Ueki, Eishi Baba, Koichi Akashi
- Organizer
  AACR annual meeting 2015
- Place of Presentation
  Pennsylvania
- Year and Date
  2015-04-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860542
[Presentation] Epithelial to mesenchymal transition by TGF-beta induced cancer stem-like property in primary colorectal cancer2015
- Author(s)
  中野倫孝、有山寛、田村真吾、磯部大地、宮脇恒太、奥村祐太、草場仁志、植木隆、馬場英司、赤司浩一
- Organizer
  日本臨床腫瘍学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2015-07-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860542
[Presentation] Plasticity of CD44+ colorectal cancer cell depends on TGF-beta induced EMT2015
- Author(s)
  Michitaka Nakano, Hiroshi Ariyama, Shingo Tamura, Taichi Isobe, Kohta Miyawaki, Yuta Okumura, Hitoshi Kusaba, Takashi Ueki, Eishi Baba, Koichi Akashi
- Organizer
  AACR annual meeting 2015
- Place of Presentation
  Pennsylvania
- Year and Date
  2015-04-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] EMT induces sphere forming ability in primary colorectal cancer2015
- Author(s)
  Michitaka Nakano, Hiroshi Ariyama, Shingo Tamura, Taichi Isobe, Kohta Miyawaki, Yuta Okumura, Hitoshi Kusaba, Takashi Ueki, Eishi Baba, Koichi Akashi
- Organizer
  第13回幹細胞シンポジウム
- Place of Presentation
  東京
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-25860542
[Presentation] EMT induces sphere forming ability in primary colorectal cancer2015
- Author(s)
  Michitaka Nakano, Hiroshi Ariyama, Shingo Tamura, Taichi Isobe, Kohta Miyawaki, Yuta Okumura, Hitoshi Kusaba, Takashi Ueki, Eishi Baba, Koichi Akashi
- Organizer
  第13回幹細胞シンポジウム
- Place of Presentation
  東京大学
- Year and Date
  2015-05-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08970
[Presentation] Placiticity of CD44+ colorectal cancer stem cells depend on TGF-beta-induced epithelial mesenchymal transition：evidences from an ex vivo culture2014
- Author(s)
  Michitaka Nakano, Hiroshi Ariyama, Shingo Tamura, Taichi Isobe, Kohta Miyawaki, Hitoshi Kusaba, Takashi Ueki, Eishi Baba, Koichi Akashi
- Organizer
  AACR
- Place of Presentation
  San Diego
- Year and Date
  2014-04-07
- Data Source
  KAKENHI-PROJECT-25860542
[Presentation] Placiticity of CD44+ colorectal cancer stem cells depend on TGF-beta-induced epithelial mesenchymal transition：evidences from an ex vivo culture
- Author(s)
  中野倫孝,有山寛、田村真吾、磯部大地、宮脇恒太、奥村祐太、草場仁志、植木隆、馬場英司、赤司浩一
- Organizer
  第73回癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25860542
[Presentation] Placiticity of CD44+ colorectal cancer stem cells depend on TGF-beta-induced epithelial mesenchymal transition：evidences from an ex vivo culture
- Author(s)
  中野倫孝,有山寛、田村真吾、磯部大地、宮脇恒太、奥村祐太、草場仁志、植木隆、馬場英司、赤司浩一
- Organizer
  第12回臨床腫瘍学会
- Place of Presentation
  福岡
- Year and Date
  2014-07-17 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-25860542

1. Baba Eishi (00315475)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. Arita Shuji (20544935)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. NAKANO Michitaka

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
4. TANAKA Mamoru

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 赤司浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 菊繁吉謙

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ariyama Hiroshi 有山 寛

ARIYAMA Hiroshi 有山 寛

Research Projects

Research Products

Co-Researchers

Establishment of carcinogenesis model of intestinal type gastric cancer from the organoid of atrophic gastritis patient.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Treatment resistance based on the cellular components of tertiary lymphoid structure in gastrointestinal cancers

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of in vitro human gastric signet-ring carcinogenesis model.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of differentiation and metastasis of human gastrointestinal cancer stem cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of drug sensitivity and resistance by single cell-based genetic assay and intratumoral profiling of gastric cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Macrophages are primed to transdifferentiate into fibroblasts in malignant ascites and pleural effusions2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Colorectal cancer stem cell population consist of heterogeneous cells based on E-cadherin expression with different tumorigenic potential in vivo2018

Author(s)

Journal Title

Data Source

[Journal Article] Efficacy and safety analysis of oxaliplatin-based chemotherapy for advanced gastric cancer with a prior treatment of cisplatin2017

Author(s)

Journal Title

Data Source

[Journal Article] Irinotecan monotherapy as third-line or later treatment in advanced gastric cancer2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Circulating "stem-like" PD-1+ CD8 T cells respond to PD-1 blockade and predict clinical outcomes in esophageal cancer2022

Author(s)

Organizer

Data Source

[Presentation] The risk factors for oxaliplatin-induced thrombocytopenia and neuropathy in advanced gastric cancer2017

Author(s)

Organizer

Data Source

[Presentation] マウス胃組織幹細胞の同定および印環細胞癌発癌マウスモデルの構築2017

Author(s)

Organizer

Data Source

[Presentation] 胃組織幹細胞と印環細胞癌発癌モデルマウス2017

Author(s)

Organizer

Data Source

[Presentation] 胃印環細胞癌における癌幹細胞とニッチ2017

Author(s)

Organizer

Data Source

[Presentation] 癌性腹水中TILは疲弊マーカーを高頻度で発現する2017

Author(s)

Organizer

Data Source

[Presentation] TGF-beta regulates CD44 expression of cancer cells through epithelial-to-mesenchymal transition in malignant ascites2016

Author(s)

Ariyama Hiroshi 有山寛

ARIYAMA Hiroshi 有山寛