Okamoto Naoki 岡本直樹

Researcher Number	80714360
Other IDs
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 特任助教 2025: 東京科学大学, その他の部局等, 非常勤講師
Affiliation (based on the past Project Information) *help	2025: 順天堂大学, 大学院医学研究科, 特任助教 2022 – 2024: 東京医科歯科大学, 生体材料工学研究所, 非常勤講師 2018 – 2022: 国際医療福祉大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 高齢不妊 / FSH刺激抵抗性 / 不妊治療 / FSH抵抗性 / 新規卵巣刺激法 / アンチエイジング / 抗老化サプリメント / 卵子・卵巣のアンチエイジング / サプリメント / 卵子の質の改善 … More / 卵子の老化 / NMN / 妊孕性 / エイジング … More Except Principal Investigator 早発閉経 / 卵胞活性化 / 卵巣機能不全 / 多嚢胞性卵巣症候群 / 排卵誘発 / メカノバイオロジー / 排卵障害 / IVA / 卵胞活性化療法 / HIPPOシグナル / 高齢不妊 / Hippoシグナル / 低侵襲 / 卵胞局在 / 規卵巣組織移植 / 卵巣組織移植 / 卵巣組織移植術 / ライブセルイメージング Less

プテロスチルベンを用いた妊孕能のアンチエイジングPrincipal Investigator
- Principal Investigator
  
  岡本直樹
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Juntendo University
細胞シグナル応答に基づく卵胞活性化療法の改良による卵巣機能不全治療の革新
- Principal Investigator
  
  河村和弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Juntendo University
Development of the ovulation induction for infertility with ovulation failure based on mechanobiology
- Principal Investigator
  
  河村和弘
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Juntendo University
Attempts to develop new ovarian stimulation methods for aging infertile patients.Principal Investigator
- Principal Investigator
  
  Okamoto Naoki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Tokyo Medical and Dental University
  International University of Health and Welfare
Innovation of aging infertility treatment by developing a minimally invasive in vitro activation therapy
- Principal Investigator
  
  Kawamura Kazuhiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Juntendo University
  International University of Health and Welfare
Development of a novel method of ovarian tissue grafting applying live cell imaging
- Principal Investigator
  
  Kawamura Kazuhiro
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Juntendo University
  International University of Health and Welfare
Anti-aging of fertility using NMN and NRPrincipal Investigator
- Principal Investigator
  
  Okamoto Naoki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  International University of Health and Welfare

All 2022 2020 2019 2018

All Journal Article Presentation

[Journal Article] Short-term resveratrol treatment restored the quality of oocytes in aging mice.2022
- Author(s)
  Okamoto, N., Sato, Y., Kawagoe, Y., Shimizu, T., Kawamura, K.
- Journal Title
  
  Aging
  
  Volume: 14 Issue: 14 Pages: 5628-5640
- DOI
  10.18632/aging.204157
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19607, KAKENHI-PROJECT-20H03583, KAKENHI-PROJECT-18K19624, KAKENHI-PROJECT-19H03801
[Journal Article] CXCL5-CXCR2 signaling is a senescence-associated secretory phenotype in preimplantation embryos.2020
- Author(s)
  Kawagoe Y, Kawashima I, Sato Y;Okamoto N, Matsubara K, Kawamura K
- Journal Title
  
  Aging Cell.
  
  Volume: 19
- NAID
  120007181848
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K19624
[Journal Article] Heterosis extends the reproductive ability in aged female mice†2018
- Author(s)
  Ozawa Yusuke、Watanabe Kenji、Toda Toshihiko、Shibuya Shuichi、Okumura Nobuaki、Okamoto Naoki、Sato Yorino、Kawashima Ikko、Kawamura Kazuhiro、Shimizu Takahiko
- Journal Title
  
  Biology of Reproduction
  
  Volume: 100 Issue: 4 Pages: 1082-1089
- DOI
  10.1093/biolre/ioy260
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19624, KAKENHI-PROJECT-15K20167, KAKENHI-PROJECT-16H05476
[Presentation] 早発卵巣不全患者の原因別による卵子の質の変化2020
- Author(s)
  川越雄太, 岡本直樹, 石塚文平, 河村和弘
- Organizer
  第61回日本卵子学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19624
[Presentation] サプリメントを用いた卵子の質向上への挑戦2020
- Author(s)
  岡本直樹
- Organizer
  日本生殖医学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16819
[Presentation] mTOR阻害剤による卵巣機能不全患者の卵巣予備能温存法の開発2020
- Author(s)
  佐藤可野, 岡本直樹, 川越雄太, 河村和弘
- Organizer
  第38回日本受精着床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-18K19624
[Presentation] サプリメントを用いた卵子の質向上への挑戦2020
- Author(s)
  岡本直樹
- Organizer
  日本生殖医学会
- Invited
- Data Source
  KAKENHI-PROJECT-20K18198
[Presentation] mTOR阻害剤による卵巣予備能温存法の開発2020
- Author(s)
  佐藤可野,岡本直樹, 川越雄太, 河村和弘
- Organizer
  第25回日本生殖内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-18K19624
[Presentation] Ant-aging treatment in reproductive medicine: modification of life style and trial of supplemental diet.2019
- Author(s)
  Naoki okamoto
- Organizer
  8th International Conference on NUTRITION, FOOD SCIENCE AND TECHNOLOGY
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16819

1. Kawamura Kazuhiro (10344756)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
2. 佐藤可野 (00511073)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. 川越雄太 (10609077)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 河村七美 (70323152)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 山海直 (80300937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 横尾正樹 (10396541)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 小林仁 (40234827)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 池内真志 (90377820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 清水孝彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okamoto Naoki 岡本 直樹

Research Projects

Research Products

Co-Researchers

プテロスチルベンを用いた妊孕能のアンチエイジングPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞シグナル応答に基づく卵胞活性化療法の改良による卵巣機能不全治療の革新

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of the ovulation induction for infertility with ovulation failure based on mechanobiology

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Attempts to develop new ovarian stimulation methods for aging infertile patients.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Innovation of aging infertility treatment by developing a minimally invasive in vitro activation therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel method of ovarian tissue grafting applying live cell imaging

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Anti-aging of fertility using NMN and NRPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Short-term resveratrol treatment restored the quality of oocytes in aging mice.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CXCL5-CXCR2 signaling is a senescence-associated secretory phenotype in preimplantation embryos.2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Heterosis extends the reproductive ability in aged female mice†2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 早発卵巣不全患者の原因別による卵子の質の変化2020

Author(s)

Organizer

Data Source

[Presentation] サプリメントを用いた卵子の質向上への挑戦2020

Author(s)

Organizer

Data Source

[Presentation] mTOR阻害剤による卵巣機能不全患者の卵巣予備能温存法の開発2020

Author(s)

Organizer

Data Source

[Presentation] サプリメントを用いた卵子の質向上への挑戦2020

Author(s)

Organizer

Data Source

[Presentation] mTOR阻害剤による卵巣予備能温存法の開発2020

Author(s)

Organizer

Okamoto Naoki 岡本直樹