YAMAGUCHI SHINPEI 山口新平

… Alternative Names

Yamaguchi Shinpei 山口新平

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Researcher Number	80740795
Other IDs
Affiliation (Current)	2023: 東邦大学, 理学部, 講師
Affiliation (based on the past Project Information) *help	2022 – 2023: 東邦大学, 理学部, 講師 2016 – 2021: 大阪大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 42030:Animal life science-related / Medium-sized Section 48:Biomedical structure and function and related fields / Basic Section 44020:Developmental biology-related / General medical chemistry / Biological Sciences Except Principal Investigator Biological Sciences
Keywords	Principal Investigator DNAメチル化 / 胚性幹細胞 / インプリンティング / ES細胞 / エピジェネティクス / 経世代エピゲノム / TET1 / 発生工学 / キメラ / Pum3 … More / 2細胞期胚様細胞 / クロモセンター / p53 / Zscan4 / ２細胞期胚様細胞 / 幹細胞 / 胚盤胞 / MEK阻害剤 / ゲノムインプリンティング / 未分化性 / メジャーサテライト反復配列 / ペリセントロメアヘテロクロマチン / 生殖細胞 / H3K27me3 / ペリセントロメア / 始原生殖細胞 … More Except Principal Investigator リプログラミング / 全能性幹細胞 / 全能性エピゲノム / ヒストン修飾 / 父母アレル非対称性 / ポリコーム抑制複合体 / エピゲノム / 受精卵 / エピジェネティクス / 全能性 / ポリコーム Less

Regulatory mechanisms of the transgenerational epigenome by TET1Principal Investigator
- Principal Investigator
  
  山口新平
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Toho University
The Role of Genomic Imprinting in the BrainPrincipal Investigator
- Principal Investigator
  
  山口新平
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Toho University
全能性消失時のエピゲノム制御機構の解明
- Principal Investigator
  
  井上梓
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Institute of Physical and Chemical Research
多能性幹細胞における異なる分化状態の動的維持機構Principal Investigator
- Principal Investigator
  
  山口新平
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44020:Developmental biology-related
- Research Institution
  Osaka University
始原生殖細胞特異的なヘテロクロマチン動態の解析Principal Investigator
- Principal Investigator
  
  山口新平
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
Role of genomic imprinting in the establishment of ESCsPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Shinpei
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General medical chemistry
- Research Institution
  Osaka University

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Establishment of dopaminergic neuron purification system in mice for the Parkinson’s disease study2021
- Author(s)
  Sheng Kit-Yeng、Hayakawa Hideki、Baba Kousuke、Kimura Yasuyoshi、Mochizuki Hideki、Nakano Toru、Yamaguchi Shinpei
- Journal Title
  
  Biobrxive
  
  Volume: 1 Pages: 1-1
- DOI
  10.21203/rs.3.rs-296465/v1
- Open Access
- Data Source
  KAKENHI-PLANNED-19H05754
[Journal Article] Tet1 regulates epigenetic remodeling of the pericentromeric heterochromatin and chromocenter organization in DNA hypomethylated cells2021
- Author(s)
  Hagihara Yota、Asada Satoshi、Maeda Takahiro、Nakano Toru、Yamaguchi Shinpei
- Journal Title
  
  PLOS Genetics
  
  Volume: 17 Issue: 6 Pages: e1009646-e1009646
- DOI
  10.1371/journal.pgen.1009646
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05754, KAKENHI-PROJECT-19K06676
[Journal Article] Ribosomal stress induces 2-cell embryo-like state transition of the mouse ESCs through p53 activation2021
- Author(s)
  Maeda Takahiro、Kimura Yasuyoshi、Nakano Toru、Yamaguchi Shinpei
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 579 Pages: 175-180
- DOI
  10.1016/j.bbrc.2021.09.068
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-19H05754, KAKENHI-PROJECT-19K06676
[Journal Article] Nucleus‐localized adiponectin is survival gatekeeper through miR‐214‐mediated AIFM2 regulation2019
- Author(s)
  Cho Junkwon、Teshigawara Rika、Kameda Masahiro、Yamaguchi Shinpei、Tada Takashi
- Journal Title
  
  Genes to Cells
  
  Volume: 24 Issue: 2 Pages: 126-138
- DOI
  10.1111/gtc.12658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17J00350, KAKENHI-PROJECT-16H06223
[Journal Article] Distinct requirements for the maintenance and establishment of mouse embryonic stem cells2018
- Author(s)
  Konishi Riyo、Nakano Toru、Yamaguchi Shinpei
- Journal Title
  
  Stem Cell Research
  
  Volume: 31 Pages: 55-61
- DOI
  10.1016/j.scr.2018.07.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01217, KAKENHI-PROJECT-16H06223
[Journal Article] Novel miRNA biomarkers for genotoxicity screening in mouse2018
- Author(s)
  Oka Hiroyuki、Masuno Koichi、Uehara Takeki、Okamoto Toru、Matsuura Yoshiharu、Nakano Toru、Yamaguchi Shinpei
- Journal Title
  
  Toxicology
  
  Volume: 404-405 Pages: 68-75
- DOI
  10.1016/j.tox.2018.05.009
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01217, KAKENHI-PROJECT-16H06223
[Presentation] Tet1によるペリセントロメア・ヘテロクロマチンと減数分裂の制御2022
- Author(s)
  山口新平
- Organizer
  生殖細胞・減数分裂研究の過去・現在・未来／生殖細胞・減数分裂研究の最前線
- Invited
- Data Source
  KAKENHI-PLANNED-19H05754
[Presentation] Tet1によるペリセントロメア・ヘテロクロマチンと減数分裂の制御2022
- Author(s)
  山口新平
- Organizer
  生殖細胞・減数分裂研究の過去・現在・未来／生殖細胞・減数分裂研究の最前線
- Invited
- Data Source
  KAKENHI-PROJECT-19K06676
[Presentation] Tet1 によるペリセントロメア領域のリモデリングとクラスタリング2021
- Author(s)
  萩原遥太、仲野徹、山口新平
- Organizer
  日本遺伝学会第93回大会
- Data Source
  KAKENHI-PLANNED-19H05754
[Presentation] Tet1 によるペリセントロメア領域のリモデリングとクラスタリング2021
- Author(s)
  萩原遥太、仲野徹、山口新平
- Organizer
  日本遺伝学会第93回大会
- Data Source
  KAKENHI-PROJECT-19K06676
[Presentation] Tet1によるペリセントロメア領域のリモデリングと集合2020
- Author(s)
  山口新平、萩原遥太、仲野徹
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-19H05754
[Presentation] Tet1によるペリセントロメア領域のリモデリングと集合2020
- Author(s)
  山口新平、萩原遥太、仲野徹
- Organizer
  第43回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06676
[Presentation] Tet1によるペリセントロメア領域のエピジェネティックリモデリング2020
- Author(s)
  山口新平
- Organizer
  『配偶子インテグリティの構築』『全能性プログラム』合同公開シンポジウム
- Data Source
  KAKENHI-PLANNED-19H05754
[Presentation] Tet1によるペリセントロメア領域のエピジェネティックリモデリング2020
- Author(s)
  山口新平
- Organizer
  『配偶子インテグリティの構築』『全能性プログラム』合同公開シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K06676
[Presentation] Stress-dependent activation of p53 induces the transition to 2-cell embryo-like state of mouse ESC2019
- Author(s)
  山口新平、前田隆寛
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-19H05754
[Presentation] p53ファミリーによるES細胞の未分化状態制御2019
- Author(s)
  山口新平、前田隆寛
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-19H05754
[Presentation] Stress-dependent activation of p53 induces the transition to 2-cell embryo-like state of mouse ESC2019
- Author(s)
  山口新平
- Organizer
  新学術領域・全能性キックオフシンポジウム
- Invited
- Data Source
  KAKENHI-PLANNED-19H05754
[Presentation] p53ファミリーによるES細胞の未分化状態制御2019
- Author(s)
  山口新平、前田隆寛、木村康義、仲野徹
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06676
[Presentation] Transition to 2 cell embryo-like state by stress-induced p53 activation in mouse ESC2019
- Author(s)
  山口新平
- Organizer
  第13回若手研究フォーラム
- Invited
- Data Source
  KAKENHI-PROJECT-19K06676
[Presentation] Stress-dependent activation of p53 induces the transition to 2-cell embryo-like state of mouse ESC2019
- Author(s)
  山口新平
- Organizer
  International Symposium on Epigenome 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] Stress-dependent activation of p53 induces the transition to 2-cell embryo-like state of mouse ESC2019
- Author(s)
  山口新平、前田隆寛、木村康義、仲野徹
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06676
[Presentation] Transition to 2 cell embryo-like state by stress-induced p53 activation in mouse ESC2019
- Author(s)
  山口新平
- Organizer
  第13回若手研究フォーラム
- Invited
- Data Source
  KAKENHI-PLANNED-19H05754
[Presentation] Stress-dependent activation of p53 induces the transition to 2-cell embryo-like state of mouse ESC2019
- Author(s)
  山口新平
- Organizer
  新学術領域・全能性キックオフシンポジウム
- Data Source
  KAKENHI-PROJECT-19K06676
[Presentation] ストレス依存的なp53の活性化により引き起こされるZscan4陽性細胞の役割2018
- Author(s)
  前田隆寛、木村康義、仲野徹、山口新平
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] Stress-dependent p53 activation induces 2-cell embryo-like state in ESCs2018
- Author(s)
  山口新平
- Organizer
  第一回動的恒常性研究会
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] p53活性化を通じたES細胞の動的恒常性維持2018
- Author(s)
  山口新平
- Organizer
  第6回Ｘ染色体研究会
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] マウス胚性幹細胞の永続的な未分化状態の確立と維持を支える分子基盤2018
- Author(s)
  山口新平、小西理予、前田隆寛、木村康義、仲野徹
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] The mechanism and role of loss-of-imprinting in mouse embryonic stem cell2018
- Author(s)
  山口新平
- Organizer
  Cold Spring harbor meeting Epigenetics and Chromatin
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] Transition to Zscan4+ state is induced by the stress-dependent p53 activation in mouse ESC2018
- Author(s)
  山口新平
- Organizer
  West Lake Symposium on Epigenetics
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] ストレス依存的なp53の活性化により引き起こされるZscan4陽性細胞の役割2018
- Author(s)
  前田隆寛, 木村康義, 仲野徹, 山口新平
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] The mechanism and role of loss of imprinting in mouse embryonic stem cell2018
- Author(s)
  Shinpei Yamaguchi
- Organizer
  Cold Spring harbor meeting Epigenetics and Chromatin
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] Molecular mechanism of acquisition of 5hmC at pericentric region in mouse primordial germ cell2018
- Author(s)
  山口新平
- Organizer
  新学術研究領域「生殖細胞のエピゲノムダイナミクスとその制御」成果取りまとめ公開シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] Molecular mechanism of acquisition of 5hmC at pericentric region in mouse primordial germ cell2018
- Author(s)
  山口新平
- Organizer
  新学術研究領域「生殖細胞のエピゲノムダイナミクスとその制御」公開シンポジウム
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] マウス胚性幹細胞の永続的な未分化状態の確立と維持を支える分子基盤2018
- Author(s)
  山口新平, 小西理予, 前田隆寛, 木村康義, 仲野徹
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] p53活性化を通じたES細胞の動的恒常性維持2018
- Author(s)
  山口新平
- Organizer
  第6回Ｘ染色体研究会
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] Physiological function of Tet1 in germ and somatic cell development2017
- Author(s)
  Shinpei Yamaguchi
- Organizer
  International Symposium 2017 Development and Diseases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] Physiological function of Tet1 in germ and somatic cell development2017
- Author(s)
  Shinpei Yamaguchi
- Organizer
  International Symposium 2017 Development and Diseases
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] ES 細胞の樹立におけるX染色体の活性化とインプリンティング破綻2017
- Author(s)
  山口新平
- Organizer
  第5回X染色体研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] ES 細胞の樹立におけるX染色体の活性化とインプリンティング破綻2017
- Author(s)
  山口新平
- Organizer
  第5回X染色体研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] The physiological role and underlying mechanism of pericentric 5hmC in mouse primordial germ cell2017
- Author(s)
  Shinpei Yamaguchi
- Organizer
  Symposium on Epigenome Dynamics and Regulation in Germ cells
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] ES 細胞の樹立におけるインプリンティング破綻の機構と役割2017
- Author(s)
  山口新平
- Organizer
  第11回日本エピジェネティクス研究会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] The physiological role and underlying mechanism of pericentric 5hmC in mouse primordial germ cell2017
- Author(s)
  Shinpei Yamaguchi
- Organizer
  Symposium on Epigenome Dynamics and Regulation in Germ cells
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] ES 細胞の樹立におけるインプリンティング破綻の機構と役割2017
- Author(s)
  山口新平
- Organizer
  第11回日本エピジェネティクス研究会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] Function of Tet proteins in the maintenance and removal of DNA methylation in Cp G islands2016
- Author(s)
  山口新平
- Organizer
  第39 回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] Function of Tet proteins in the maintenance and removal of DNA methylation in Cp G islands2016
- Author(s)
  山口新平
- Organizer
  第39 回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] Molecular function of Tet1 in the epigenetic reprogramming through mouse germ cell development2016
- Author(s)
  山口新平
- Organizer
  第88回日本遺伝学会大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] Tetタンパク質による遺伝子発現調節領域の能動的脱メチル化2016
- Author(s)
  山口新平
- Organizer
  第10回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] ES細胞における未分化状態の確立と維持に機能するシグナル経路2016
- Author(s)
  小西理予、仲野徹、山口新平
- Organizer
  第39 回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01217
[Presentation] Molecular function of Tet1 in the epigenetic reprogramming through mouse germ cell development2016
- Author(s)
  山口新平
- Organizer
  第88回日本遺伝学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] Tetタンパク質による遺伝子発現調節領域の能動的脱メチル化2016
- Author(s)
  山口新平
- Organizer
  第10回日本エピジェネティクス研究会年会
- Data Source
  KAKENHI-PROJECT-16H06223
[Presentation] ES細胞における未分化状態の確立と維持に機能するシグナル経路2016
- Author(s)
  小西理予、仲野徹、山口新平
- Organizer
  第39 回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H06223

1. 井上梓 (60814910)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAGUCHI SHINPEI 山口 新平

Yamaguchi Shinpei 山口 新平

Research Projects

Research Products

Co-Researchers

Regulatory mechanisms of the transgenerational epigenome by TET1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The Role of Genomic Imprinting in the BrainPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

全能性消失時のエピゲノム制御機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

多能性幹細胞における異なる分化状態の動的維持機構Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

始原生殖細胞特異的なヘテロクロマチン動態の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of genomic imprinting in the establishment of ESCsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Establishment of dopaminergic neuron purification system in mice for the Parkinson’s disease study2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tet1 regulates epigenetic remodeling of the pericentromeric heterochromatin and chromocenter organization in DNA hypomethylated cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ribosomal stress induces 2-cell embryo-like state transition of the mouse ESCs through p53 activation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nucleus‐localized adiponectin is survival gatekeeper through miR‐214‐mediated AIFM2 regulation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Distinct requirements for the maintenance and establishment of mouse embryonic stem cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel miRNA biomarkers for genotoxicity screening in mouse2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Tet1によるペリセントロメア・ヘテロクロマチンと減数分裂の制御2022

Author(s)

Organizer

Data Source

[Presentation] Tet1によるペリセントロメア・ヘテロクロマチンと減数分裂の制御2022

Author(s)

Organizer

Data Source

[Presentation] Tet1 によるペリセントロメア領域のリモデリングとクラスタリング2021

YAMAGUCHI SHINPEI 山口新平

Yamaguchi Shinpei 山口新平