Hamaguchi Shogo 浜口正悟

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HAMAGUCHI Shogo 浜口正悟

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Researcher Number	80747767
Other IDs
Affiliation (Current)	2025: 東邦大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2017 – 2022: 東邦大学, 薬学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / Pharmacology in pharmacy
Keywords	Principal Investigator SERCA / 拡張機能障害 / 酸化ストレス / 薬理学 / AngiotensinⅡ / 伸展負荷 / angiotensinⅡ / 心房細動 / 自発活動 / 肺静脈心筋

Mechanism of the effect of reactive oxygen species on cardiac diastolic dysfunctionPrincipal Investigator
- Principal Investigator
  
  HAMAGUCHI Shogo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Toho University
Effect of stretch on the intracellular Ca2+-dependent spontaneous activity of pulmonary vein myocardiumPrincipal Investigator
- Principal Investigator
  
  HAMAGUCHI Shogo
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pharmacology in pharmacy
- Research Institution
  Toho University

All 2023 2022 2021 2020 2019 2018 2017 2002 Other

All Journal Article Presentation Other

[Journal Article] Mechanisms for the α-Adrenoceptor-Mediated Positive Inotropy in Mouse Ventricular Myocardium: Enhancing Effect of Action Potential Prolongation2023
- Author(s)
  Hamaguchi Shogo、Morinou Ikue、Shiseki Yuko、Mikami Ayako、Seki Maika、Namekata Iyuki、Tanaka Hikaru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 4 Pages: 3926-3926
- DOI
  10.3390/ijms24043926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Journal Article] Negative Inotropic Effects of Class I Antiarrhythmics on Guinea Pig Ventricular Myocardium: Correlation with L-Type Ca2+ Channel Blockade2023
- Author(s)
 Hiiro Haruhito、Hashimoto Tatsuki、Mizoguchi Makoto、Kaneko Mika、Deguchi Nanoka、Takahashi Yuna、Hamaguchi Shogo、Namekata Iyuki、Tanaka Hikaru
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 46 Issue: 1 Pages: 133-137
- DOI
 10.1248/bpb.b22-00644
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2023-01-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Journal Article] Negative Chronotropic Effects of Class I Antiarrhythmic Drugs on Guinea Pig Right Atria: Correlation with L-Type Ca2+ Channel Blockade2023
- Author(s)
  Hiiro Haruhito、Otsuka Kentaro、Hamaguchi Shogo、Namekata Iyuki、Tanaka Hikaru
- Journal Title
  
  J
  
  Volume: 6 Issue: 1 Pages: 104-114
- DOI
  10.3390/j6010008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Journal Article] Inhibitory Effect of a Late Sodium Current Blocker, NCC-3902, on the Automaticity of the Guinea Pig Pulmonary Vein Myocardium2022
- Author(s)
  Namekata Iyuki、Hiiro Haruhito、Odaka Ryosuke、Saito Taro、Hamaguchi Shogo、Tsukamoto Tadaaki、Ishikawa Ryutaro、Katayama Yoshimi、Kondo Yoshiki、Tanaka Hikaru
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 11 Pages: 1644-1652
- DOI
  10.1248/bpb.b22-00362
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Journal Article] Intracellular Ca2+-Mediated Mechanisms for the Pacemaker Depolarization of the Mouse and Guinea Pig Sinus Node Tissue2022
- Author(s)
  Namekata Iyuki、Jitsukata Kento、Fukuda Ayumi、Odaka Ryosuke、Hamaguchi Shogo、Tanaka Hikaru
- Journal Title
  
  Biomolecules
  
  Volume: 12 Issue: 3 Pages: 377-377
- DOI
  10.3390/biom12030377
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Journal Article] Contribution of ATP-Mediated Positive Feedback to Sympathetic Nerve-Induced Positive Inotropy in Guinea Pig Ventricular Myocardium2021
- Author(s)
  Hamaguchi Shogo、Kariya Marin、Ozaki Aya F.、Namekata Iyuki、Tanaka Hikaru
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 3 Pages: 458-460
- DOI
  10.1248/bpb.b20-00732
- NAID
  130007993439
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K16013, KAKENHI-PROJECT-20K07299
[Journal Article] Positive Lusitropic Effect of Quercetin on Isolated Ventricular Myocardia from Normal and Streptozotocin-Induced Diabetic Mice2021
- Author(s)
  Hamaguchi Shogo、Abe Kohei、Komatsu Momoka、Kainuma Jun、Namekata Iyuki、Tanaka Hikaru
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 44 Issue: 12 Pages: 1894-1897
- DOI
  10.1248/bpb.b21-00580
- NAID
  130008123499
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2021-12-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Journal Article] Fluorescence Discrimination of Pharmacological Effects on the Na+–Ca2+ Exchanger and Sarco-Endoplasmic Reticulum Ca2+-ATPase in Mouse Ventricular Cardiomyocytes2021
- Author(s)
 Namekata Iyuki、Odaka Ryosuke、Hamazaki Shunsuke、Nisaka Hina、Hamaguchi Shogo、Tanaka Hikaru
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 44 Issue: 1 Pages: 154-157
- DOI
 10.1248/bpb.b20-00701
- NAID
 130007965347
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2021-01-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Journal Article] KB-R7943 Inhibits the Mitochondrial Ca2+ Uniporter but Not Na+–Ca2+ Exchanger in Cardiomyocyte-Derived H9c2 Cells2020
- Author(s)
 Namekata Iyuki、Odaka Ryosuke、Hamaguchi Shogo、Tanaka Hikaru
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 43 Issue: 12 Pages: 1993-1996
- DOI
 10.1248/bpb.b20-00747
- NAID
 130007948741
- ISSN
 0918-6158, 1347-5215
- Year and Date
 2020-12-01
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Journal Article] Differential effects of class I antiarrhythmic drugs on the guinea pig pulmonary vein myocardium: Inhibition of automatic activity correlates with blockade of a diastolic sodium current component2020
- Author(s)
  Irie Masahiko、Hiiro Haruhito、Kato Shu、Kuramochi Mizuki、Hamaguchi Shogo、Namekata Iyuki、Tanaka Hikaru
- Journal Title
  
  Journal of pharmacological sciences
  
  Volume: 143(4) Issue: 4 Pages: 325-329
- DOI
  10.1016/j.jphs.2020.05.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Journal Article] Involvement of the persistent Na+ current in the diastolic depolarization and automaticity of the guinea pig pulmonary vein myocardium2019
- Author(s)
  Irie Masahiko、Hiiro Haruhito、Hamaguchi Shogo、Namekata Iyuki、Tanaka Hikaru
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 141 Issue: 1 Pages: 9-16
- DOI
  10.1016/j.jphs.2019.08.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08607, KAKENHI-PROJECT-17K15460
[Journal Article] Angiotensin II Induces Automatic Activity of the Isolated Guinea Pig Pulmonary Vein Myocardium through Activation of the IP3 Receptor and the Na+-Ca2+ Exchanger2019
- Author(s)
  Tanaka Yusuke、Obata Kae、Ohmori Tamano、Ishiwata Kohei、Abe Manato、Hamaguchi Shogo、Namekata Iyuki、Tanaka Hikaru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 7 Pages: 1768-1768
- DOI
  10.3390/ijms20071768
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08607, KAKENHI-PROJECT-17K15460
[Journal Article] Resistance of Fetal Guinea Pig Ventricular Myocardium to Hypoxia: Maintained Intracellular ATP Prevents the Opening of ATP-Sensitive Potassium Channels2019
- Author(s)
  Naoki Agata, Yoshimitsu Kato, Shogo Hamaguchi, Iyuki Namekata, Hikaru Tanaka.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 2 Pages: 268-272
- DOI
  10.1248/bpb.b18-00762
- NAID
  130007601240
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08607, KAKENHI-PROJECT-17K15460
[Journal Article] Cell Morphology and Early-phase Ca2+ Transients of Guinea-Pig Pulmonary Vein Cardiomyocytes Compared with Atrial and Ventricular Cardiomyocytes2019
- Author(s)
 Iyuki Namekata, Yusuke Tanaka, Tamano Ohmori, Yayoi Tsuneoka, Shogo Hamaguchi, Hikaru Tanaka
- Journal Title
 
 bioimages
 
 Volume: 27 Issue: 0 Pages: 1-12
- DOI
 10.11169/bioimages.27.1
- NAID
 130007638801
- ISSN
 0919-2719
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17K15460, KAKENHI-PROJECT-17K18146, KAKENHI-PROJECT-17K08607
[Journal Article] Acceleratory effect of ellagic acid on sarcoplasmic reticulum Ca2+ uptake and myocardial relaxation2018
- Author(s)
  Iyuki Namekata, Haruhito Hiiro, Haruna Kanae, Ayako Yoshino, Akihiro Kazama, Shogo Hamaguchi, Naoko Iida-Tanaka and Hikaru Tanaka
- Journal Title
  
  Int J Hum Cult Stud.
  
  Volume: 28 Pages: 701-707
- NAID
  130007683979
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15460
[Journal Article] Fluorescence Analysis of the Mitochondrial Effect of a Plasmalemmal Na+/Ca2+ Exchanger Inhibitor, SEA0400, in Permeabilized H9c2 Cardiomyocytes2017
- Author(s)
 Iyuki Namekata, Shogo Hamaguchi, Naoko Iida-Tanaka, Taichi Kusakabe, Keisuke Kato, Toru Kawanishi, Hikaru Tanaka
- Journal Title
 
 Biological and Pharmaceutical Bulletin
 
 Volume: 40 Issue: 9 Pages: 1551-1555
- DOI
 10.1248/bpb.b17-00079
- NAID
 130006038739
- ISSN
 0918-6158, 1347-5215
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-17K08607, KAKENHI-PROJECT-17K15460, KAKENHI-PROJECT-15K07871, KAKENHI-PROJECT-15K08247
[Journal Article] Fluorescence imaging-based analysis of the mitochondrial permeability transition pore opening in cardiomyocyte-derived H9c2 cells2017
- Author(s)
  Namekata Iyuki、Kanazawa Atsuko、Hamaguchi Shogo、Tanaka Hikaru、Iida-Tanaka Naoko
- Journal Title
  
  International Journal of Human Culture Studies
  
  Volume: 27 Pages: 14-19
- NAID
  130007828169
- Open Access
- Data Source
  KAKENHI-PROJECT-17K15460
[Journal Article] Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway.2017
- Author(s)
  Huiling Jin, Takayuki Fujita, Meihua Jin, Reiko Kurotani, Iyuki Namekata, Shogo Hamaguchi, Yuko Hidaka, Wenqian Cai, Kenji Suita, Yoshiki Ohnuki, Yasumasa Mototani, Kouichi Shiozawa, Rajesh Prajapati, Chen Liang, Masanari Umemura, Utako Yokoyama, Motohiko Sato, Hikaru Tanaka, Satoshi Okumura, Yoshihiro Ishikawa.
- Journal Title
  
  J Mol Cell Cardiol.
  
  Volume: 108 Pages: 170-180
- DOI
  10.1016/j.yjmcc.2017.05.014
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08607, KAKENHI-PROJECT-17K19403, KAKENHI-PROJECT-15K18973, KAKENHI-PROJECT-17K15460, KAKENHI-PROJECT-16H05358, KAKENHI-PROJECT-15K08247, KAKENHI-PROJECT-15K09208, KAKENHI-PROJECT-15H05761, KAKENHI-PROJECT-16H05300
[Journal Article] Haruna Kanae, Shogo Hamaguchi, Yumi Wakasugi, Taichi Kusakabe, Keisuke Kato, Iyuki Namekata, Hikaru Tanaka. Pathological prolongation of action potential duration as a cause of the reduced alpha-adrenoceptor-mediated negative inotropy in streptozotocin-induced diabetic mice myocardium.2017
- Author(s)
  Haruna Kanae, Shogo Hamaguchi, Yumi Wakasugi, Taichi Kusakabe, Keisuke Kato, Iyuki Namekata, Hikaru Tanaka.
- Journal Title
  
  J Pharmacol Sci.
  
  Volume: 135（3） Issue: 3 Pages: 131-133
- DOI
  10.1016/j.jphs.2017.10.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08607, KAKENHI-PROJECT-17K15460, KAKENHI-PROJECT-15K07871, KAKENHI-PROJECT-15K08247
[Journal Article] Bioimaging for Study of the Myocardial Function: Fluorescence Microscopy Featuring the Na+-Ca2+ Exchanger2002
- Author(s)
 Namekata Iyuki、Ryosuke Odaka、Shogo Hamaguchi、Hikaru Tanaka
- Journal Title
 
 bioimages
 
 Volume: 30 Issue: 0 Pages: 1-14
- DOI
 10.11169/bioimages.30.1
- ISSN
 0919-2719
- Language
 English
- Open Access
- Data Source
 KAKENHI-PROJECT-20K07091, KAKENHI-PROJECT-20K07299, KAKENHI-PROJECT-20K16013
[Presentation] Insulin signaling deficiency is responsible for diastolic dysfunction of diabetic cardiomyopathy2019
- Author(s)
  Yoshinori Mikami, Masanori Ito, Shogo Hamaguchi, Shingo Murakami, Taichiro Tomida, Daisuke Ohshima, Iyuki Namekata, Hikaru Tanaka and Satomi Adachi-Akahane
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies Congress (FAOPS2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15460
[Presentation] Impaired insulin signaling is responsible for left ventricular diastolic dysfunction in the early stage of diabetic cardiomyopathy2019
- Author(s)
  Yoshinori Mikami、 Shogo Hamaguchi、 Masanori Ito、 Shingo Murakami、 Iyuki Namekata、 Taichiro Tomida、 Daisuke Ohshima、 Hikaru Tanaka、 Satomi Adachi-Akahane
- Organizer
  第３回日本循環器学会基礎フォーラム
- Data Source
  KAKENHI-PROJECT-17K15460
[Presentation] Mechanisms for Ca2+ signaling defects underlying diastolic dysfunction in diabetic cardiomyopathy.2018
- Author(s)
  Yoshinori Mikami, Masanori Ito, Shogo Hamaguchi, Shingo Murakami, Taichiro Tomida, Iyuki Namekata, Hikaru Tanaka, Satomi Adachi-Akahane
- Organizer
  The 2nd JCS Council Forum on Basic CardioVascular Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15460
[Presentation] Intracellular calcium and membrane potential oscillation in the pulmonary vein myocardium.2018
- Author(s)
  Iyuki Namekata, Masahiko Irie, Haruna Kanae, Tsuneoka Yayoi, Shogo Hamaguchi, Hikaru Tanaka.
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15460
[Presentation] Molecular mechanism of diastolic dysfunction in the early stage of diabetic cardiomyopathy2018
- Author(s)
  Yoshinori Mikami, Masanori Ito, Shogo Hamaguchi, Shingo Murakami, Taichiro Tomida, Daisuke Ohshima, Iyuki Namekata, Hikaru Tanaka and Satomi Adachi-Akahane
- Organizer
  第41回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-17K15460
[Presentation] Defective Ca2+ signaling contributes to diastolic dysfunction in diabetic cardiomyopathy.2018
- Author(s)
  Yoshinori Mikami, Masanori Ito, Shogo Hamaguchi, Shingo Murakami, Taichiro Tomida, Iyuki Namekata, Hikaru Tanaka, Satomi Adachi-Akahane
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15460
[Presentation] L-DOPA CHE, an L-DOPA antagonist, protects neurostimulated contractile response in mice heart.2018
- Author(s)
  Tatsuo Hashimoto, Shogo Hamaguchi, Daiki Masukawa, Motokazu Koga, Masayuki Nakano, Hikaru Tanaka, Koichi Tamura, Yoshio Goshima
- Organizer
  18th World Congress of Basic and Clinical Pharmacology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15460
[Presentation] Fluorescence analysis of plasmalemmal and mitochondrial Na+-Ca2+ exchanger activity in permeabilized H9c2 cardiomyocytes2017
- Author(s)
  Hikaru Tanaka、Iyuki Namekata、Shogo Hamaguchi、Naoko Iida-Tanaka、Toru Kawanishi
- Organizer
  第26回日本バイオイメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-17K15460
[]
[]

1. NAMEKATA Iyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 田中光

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Hamaguchi Shogo 浜口 正悟

HAMAGUCHI Shogo 浜口 正悟

Research Projects

Research Products

Co-Researchers

Mechanism of the effect of reactive oxygen species on cardiac diastolic dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of stretch on the intracellular Ca2+-dependent spontaneous activity of pulmonary vein myocardiumPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mechanisms for the α-Adrenoceptor-Mediated Positive Inotropy in Mouse Ventricular Myocardium: Enhancing Effect of Action Potential Prolongation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Negative Inotropic Effects of Class I Antiarrhythmics on Guinea Pig Ventricular Myocardium: Correlation with L-Type Ca<sup>2+</sup> Channel Blockade2023

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Negative Chronotropic Effects of Class I Antiarrhythmic Drugs on Guinea Pig Right Atria: Correlation with L-Type Ca2+ Channel Blockade2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibitory Effect of a Late Sodium Current Blocker, NCC-3902, on the Automaticity of the Guinea Pig Pulmonary Vein Myocardium2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Intracellular Ca2+-Mediated Mechanisms for the Pacemaker Depolarization of the Mouse and Guinea Pig Sinus Node Tissue2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Contribution of ATP-Mediated Positive Feedback to Sympathetic Nerve-Induced Positive Inotropy in Guinea Pig Ventricular Myocardium2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Positive Lusitropic Effect of Quercetin on Isolated Ventricular Myocardia from Normal and Streptozotocin-Induced Diabetic Mice2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Fluorescence Discrimination of Pharmacological Effects on the Na<sup>+</sup>–Ca<sup>2+</sup> Exchanger and Sarco-Endoplasmic Reticulum Ca<sup>2+</sup>-ATPase in Mouse Ventricular Cardiomyocytes2021

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] KB-R7943 Inhibits the Mitochondrial Ca<sup>2+</sup> Uniporter but Not Na<sup>+</sup>–Ca<sup>2+</sup> Exchanger in Cardiomyocyte-Derived H9c2 Cells2020

Author(s)

Journal Title

DOI

NAID

Hamaguchi Shogo 浜口正悟

HAMAGUCHI Shogo 浜口正悟