yokoo takeshi 横尾健

… Alternative Names

Yokoo Takeshi 横尾健

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Researcher Number	80750629
Other IDs	https://orcid.org/0000-0001-7138-1785
Affiliation (Current)	2025: 新潟大学, 医歯学総合病院, 講師
Affiliation (based on the past Project Information) *help	2020 – 2024: 新潟大学, 医歯学総合研究科, 特任准教授 2018 – 2019: 新潟大学, 医歯学総合研究科, 特任助教 2016 – 2017: 新潟大学, 医歯学総合研究科, 客員研究員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 50020:Tumor diagnostics and therapeutics-related / Gastroenterology
Keywords	Principal Investigator DNA損傷チェックポイント / chk2 / chk1 / ccndbp1 / 遺伝子治療 / 肝線維化率 / ハイドロダイナミック遺伝子導入 / 肝硬変モデルラット / ハイドロダイナミック遺伝子導入法 / MMP13 / 肝硬変 … More Except Principal Investigator … More ハイドロダイナミック遺伝子導入法 / エクソソーム / 遺伝子治療 / 非アルコール性脂肪肝炎 / 線維化 / 間葉系幹細胞 / 核酸医薬 / 肝癌 / 難治癌 / in vivo / ゲノム編集 / テーラーメイド治療 / 病態マーカー / 胆管発癌モデル / ラット胆管発癌モデル / 胆管癌 / 膵癌 / 膵癌遺伝子治療 / 膵臓癌 / 肝細胞癌 / NASH / 腫瘍 / 虚血性心疾患 / 肝外悪性腫瘍 / プロテオーム解析 / 肝外合併症 / 非アルコール性脂肪肝疾患 / 内視鏡的粘膜切除 / コラゲナーゼ / 瘢痕狭窄 / 痔瘻モデル / 瘻孔モデル / トリアムシノロン / ESD / 内視鏡的粘膜下層剥離術 / 皮膚瘻孔モデル / 食道狭窄 / 肝臓特異的遺伝子導入 / 肝癌遺伝子治療法 / 肝癌遺伝子治療 / ジフテリアトキシン Less

Development of Organ- and Cell-specific In Vivo Genome Editing Technique as a Novel Approach for Cancer Gene Therapy
- Principal Investigator
  
  上村顕也
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Niigata University
遺伝子導入によるラット胆管癌モデルの確立と浸潤能評価による病態マーカー開発
- Principal Investigator
  
  五十嵐聡
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Development of Hydrodynamics-based Gene Therapy for the Pancreatic Cancer
- Principal Investigator
  
  Kamimura Kenya
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
肝発癌におけるCCNDBP1とDNA損傷チェックポイント機構の関連性の解明Principal Investigator
- Principal Investigator
  
  横尾健
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Efficacy of mesenchymal stem cell for prevention of esophageal stricture after endoscopic submucosal dissection
- Principal Investigator
  
  Hashimoto Satoru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Mechanisms of extrahepatic complications in NAFLD/NASH with focus on exosomes
- Principal Investigator
  
  Takamura Masaaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
Development of a treatment to improve fibrosis and elucidation of carcinogenesis mechanisms in improved NASH model MC4RKO mice
- Principal Investigator
  
  Terai Shuji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Niigata University
肝臓特異的ハイドロダイナミック法による核酸医薬送達と肝癌遺伝子治療法への応用
- Principal Investigator
  
  Kamimura Kenya
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University
Development of gene therapy for liver cirrhosis utilizing MMP13Principal Investigator
- Principal Investigator
  
  Yokoo Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Niigata University

All 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] Nucleic acid-based therapy: Development of a non-viral-based delivery approach in In Vivo and Ex Vivo Gene Therapy for Inherited and Non-Inherited Disorders2019
- Author(s)
  Takeshi Yokoo, Kenya Kamimura, Tsutomu Kanefuji, Takeshi Suda and Shuji Terai
- Total Pages
  18
- Publisher
  IntechOpen Limited
- Data Source
  KAKENHI-PROJECT-17K09408
[Journal Article] Similarity of oncogenic protein expression in KRAS gene delivery-based rat pancreatic cancer model to that of human pancreatic cancer2023
- Author(s)
  Tanaka Yuto、Kamimura Kenya、Shibata Osamu、Ogawa Kohei、Oda Chiyumi、Abe Hiroyuki、Ikarashi Satoshi、Hayashi Kazunao、Yokoo Takeshi、Wakai Toshifumi、Terai Shuji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 673 Pages: 29-35
- DOI
  10.1016/j.bbrc.2023.06.057
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07889, KAKENHI-PROJECT-21K07910, KAKENHI-PROJECT-22K15960
[Journal Article] Longitudinal increase in albumin?bilirubin score is associated with non-malignancy-related mortality and quality of life in patients with liver cirrhosis2022
- Author(s)
  Sakamaki A, Takamura M, Sakai N, Watanabe Y, Arao Y, Kimura N, Setsu T, Abe H, Yokoo T, Kamimura H, Tsubata S, Waguri N, Ishikawa T, Kawai H, Sugitani S, Sato T, Funakoshi K, Watanabe M, Igarashi K, Kamimura K, et al.
- Journal Title
  
  PLOS ONE
  
  Volume: 17 Issue: 2 Pages: e0263464-e0263464
- DOI
  10.1371/journal.pone.0263464
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08379
[Journal Article] Effects of a novel selective PPARα modulator, statin, sodium-glucose cotransporter 2 inhibitor, and combinatorial therapy on the liver and vasculature of medaka nonalcoholic steatohepatitis model2022
- Author(s)
  Kimura Atsushi、Kamimura Kenya、Ohkoshi-Yamada Marina、Shinagawa-Kobayashi Yoko、Goto Ryo、Owaki Takashi、Oda Chiyumi、Shibata Osamu、Morita Shinichi、Sakai Norihiro、Abe Hiroyuki、Yokoo Takeshi、Sakamaki Akira、Kamimura Hiroteru、Terai Shuji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 596 Pages: 76-82
- DOI
  10.1016/j.bbrc.2022.01.086
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K19478, KAKENHI-PROJECT-20K08379
[Journal Article] Cyclin D1 Binding Protein 1 Responds to DNA Damage through the ATM / CHK2 Pathway2022
- Author(s)
  Niwa Yusuke、Kamimura Kenya、Ogawa K、Oda C、Tanaka Y、Horigome R、Ohtsuka M、Miura H、Fujisawa Koichi、Yamamoto Naoki、Takami Taro、Okuda Shujiro、Ko Masayoshi、Owaki Takashi、Kimura Atsushi、Shibata Osamu、Morita Shinichi、Sakai N、Abe H、Yokoo T、Sakamaki A、Kamimura H、Terai S
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 11 Issue: 3 Pages: 851-851
- DOI
  10.3390/jcm11030851
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08289, KAKENHI-PROJECT-20K17043, KAKENHI-PROJECT-20K08326, KAKENHI-PROJECT-20H03663, KAKENHI-PROJECT-20K08379
[Journal Article] Effects of a selective PPARα modulator, sodium-glucose cotransporter 2 inhibitor, and statin on the myocardial morphology of medaka nonalcoholic fatty liver disease model2022
- Author(s)
  Ohkoshi-Yamada Marina、Kamimura Kenya、Kimura Atsushi、Tanaka Yuto、Nagayama Itsuo、Yakubo Shunta、Abe Hiroyuki、Yokoo Takeshi、Sakamaki Akira、Kamimura Hiroteru、Terai Shuji
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 625 Pages: 116-121
- DOI
  10.1016/j.bbrc.2022.07.117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08326, KAKENHI-PROJECT-21K19478, KAKENHI-PROJECT-20K08379
[Journal Article] Establishment of a pancreatic cancer animal model using the pancreas-targeted hydrodynamic gene delivery method2022
- Author(s)
  Shibata Osamu、Kamimura Kenya、Tanaka Yuto、Ogawa Kohei、Owaki Takashi、Oda Chiyumi、Morita Shinichi、Kimura Atsushi、Abe Hiroyuki、Ikarashi Satoshi、Hayashi Kazunao、Yokoo Takeshi、Terai Shuji
- Journal Title
  
  Molecular Therapy - Nucleic Acids
  
  Volume: 28 Pages: 342-352
- DOI
  10.1016/j.omtn.2022.03.019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07889, KAKENHI-PROJECT-21K07910, KAKENHI-PROJECT-22K15960, KAKENHI-PROJECT-20K08379, KAKENHI-PROJECT-20K22800
[Journal Article] Involvement of the liver-gut peripheral neural axis in nonalcoholic fatty liver disease pathologies via hepatic HTR2A2022
- Author(s)
  Owaki Takashi、Kamimura Kenya、Ko Masayoshi、Nagayama Itsuo、Nagoya Takuro、Shibata Osamu、Oda Chiyumi、Morita Shinichi、Kimura Atsushi、Sato Takeki、Setsu Toru、Sakamaki Akira、Kamimura Hiroteru、Yokoo Takeshi、Terai Shuji
- Journal Title
  
  Disease Models & Mechanisms
  
  Volume: 15 Issue: 7
- DOI
  10.1242/dmm.049612
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08326, KAKENHI-PROJECT-21K19478, KAKENHI-PROJECT-20K08379
[Journal Article] The prognosis and incidence of hepatic encephalopathy of patients with liver cirrhosis treated with proton pump inhibitors2021
- Author(s)
  Sakamaki Akira、Kamimura Kenya、Yokoo Takeshi、Osaki Akihiko、Yoshikawa Seiichi、Arao Yoshihisa、Setsu Toru、Kamimura Hiroteru、Waguri Nobuo、Takeuchi Manabu、Funakoshi Kazuhiro、Terai Shuji
- Journal Title
  
  Medicine
  
  Volume: 100 Issue: 32 Pages: e26902-e26902
- DOI
  10.1097/md.0000000000026902
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08326, KAKENHI-PROJECT-20K08379
[Journal Article] Adipose most abundant 2 protein is a predictive marker for cisplatin sensitivity in cancers2021
- Author(s)
  Kamimura Kenya、Suda Takeshi、Fukuhara Yasuo、Okuda Shujiro、Watanabe Yu、Yokoo Takeshi、Osaki Akihiko、Waguri Nobuo、Ishikawa Toru、Sato Toshihiro、Aoyagi Yutaka、Takamura Masaaki、Wakai Toshifumi、Terai Shuji
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 6255-6255
- DOI
  10.1038/s41598-021-85498-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08379, KAKENHI-PROJECT-21K19478
[Journal Article] Modulation of serotonin in the gut-liver neural axis ameliorates the fatty and fibrotic changes in non-alcoholic fatty liver2021
- Author(s)
  Ko Masayoshi、Kamimura Kenya、Owaki Takashi、Nagoya Takuro、Sakai Norihiro、Nagayama Itsuo、Niwa Yusuke、Shibata Osamu、Oda Chiyumi、Morita Shinichi、Kimura Atsushi、Inoue Ryosuke、Setsu Toru、Sakamaki Akira、Yokoo Takeshi、Terai Shuji
- Journal Title
  
  Disease Models & Mechanisms
  
  Volume: 14 Issue: 3
- DOI
  10.1242/dmm.048922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08379, KAKENHI-PROJECT-21K19478
[Journal Article] Ghrelin-insulin-like growth factor-1 axis is activated via autonomic neural circuits in the non-alcoholic fatty liver disease.2020
- Author(s)
  Nagoya T, Kamimura K, Inoue R, Ko M, Owaki T, Niwa Y, Sakai N, Setsu T, Sakamaki A, Yokoo T, Kamimura H, Nakamura Y, Ueno M, Terai S.
- Journal Title
  
  Neurogastroenterol Motil
  
  Volume: 32 Issue: 5
- DOI
  10.1111/nmo.13799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19443, KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-18K19537, KAKENHI-PROJECT-20K08379
[Journal Article] Effect of Diphtheria Toxin-Based Gene Therapy for Hepatocellular Carcinoma2020
- Author(s)
  Kamimura Kenya、Yokoo Takeshi、Abe Hiroyuki、Sakai Norihiro、Nagoya Takuro、Kobayashi Yuji、Ohtsuka Masato、Miura Hiromi、Sakamaki Akira、Kamimura Hiroteru、Miyamura Norio、Nishina Hiroshi、Terai Shuji
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 2 Pages: 472-472
- DOI
  10.3390/cancers12020472
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-18K19392, KAKENHI-PROJECT-18K19537, KAKENHI-PROJECT-20K08379, KAKENHI-PROJECT-20H03381, KAKENHI-PROJECT-16KK0189
[Journal Article] Nucleic Acid-Based Therapy: Development of a Nonviral-Based Delivery Approach2019
- Author(s)
  Yokoo Takeshi、Kamimura Kenya、Kanefuji Tsutomu、Suda Takeshi、Terai Shuji
- Journal Title
  
  In Vivo and Ex Vivo Gene Therapy for Inherited and Non-Inherited Disorders
  
  Volume: 1 Pages: 3-20
- DOI
  10.5772/intechopen.80741
- ISBN
  9781789857177, 9781789857184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K19333
[Journal Article] Considerations of elderly factors to manage the complication of liver cirrhosis in elderly patients2019
- Author(s)
  Kamimura Kenya、Sakamaki Akira、Kamimura Hiroteru、Setsu Toru、Yokoo Takeshi、Takamura Masaaki、Terai Shuji
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 25 Issue: 15 Pages: 1817-1827
- DOI
  10.3748/wjg.v25.i15.1817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-18K19537
[Journal Article] Inhibition of sodium glucose cotransporter 2 (SGLT2) delays liver fibrosis in a medaka model of nonalcoholic steatohepatitis (NASH)2019
- Author(s)
  Goto Ryo、Kamimura Kenya、Shinagawa‐Kobayashi Yoko、Sakai Norihiro、Nagoya Takuro、Niwa Yusuke、Ko Masayoshi、Ogawa Kohei、Inoue Ryosuke、Yokoo Takeshi、Sakamaki Akira、Kamimura Hiroteru、Abe Satoshi、Nishina Hiroshi、Terai Shuji
- Journal Title
  
  FEBS Open Bio
  
  Volume: 9 Issue: 4 Pages: 643-652
- DOI
  10.1002/2211-5463.12598
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06691, KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-18K19537
[Journal Article] <p>Effective prevention of sorafenib-related vascular damage induced adverse events and maintenance of hepatic function by dried bonito broth and histidine</p>2019
- Author(s)
  Sakai Norihiro、Kamimura Kenya、Shinagawa-Kobayashi Yoko、Nagoya Takuro、Niwa Yusuke、Ko Masayoshi、Setsu Toru、Sakamaki Akira、Yokoo Takeshi、Abe Satoshi、Kamimura Hiroteru、Sugitani Soichi、Yanagi Masahiko、Terai Shuji
- Journal Title
  
  Cancer Management and Research
  
  Volume: Volume 11 Pages: 4437-4448
- DOI
  10.2147/cmar.s201424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-18K19537
[Journal Article] Gene Therapy for Liver Cancers: Current Status from Basic to Clinics2019
- Author(s)
  Kamimura Kenya、Yokoo Takeshi、Abe Hiroyuki、Terai Shuji
- Journal Title
  
  Cancers
  
  Volume: 11 Issue: 12 Pages: 1865-1865
- DOI
  10.3390/cancers11121865
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09408
[Journal Article] Rational arrangement of measuring shear wave speed in the liver2019
- Author(s)
  Yokoo Takeshi、Kanefuji Tsutomu、Suda Takeshi、Nagayama Itsuo、Hoshi Takahiro、Abe Satoshi、Morita Shinichi、Kamimura Hiroteru、Kamimura Kenya、Tsuchiya Atsunori、Takamura Masaaki、Yagi Kazuyoshi、Terai Shuji
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 25 Issue: 20 Pages: 2503-2513
- DOI
  10.3748/wjg.v25.i20.2503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09408
[Journal Article] Gene Therapy for Pancreatic Diseases: Current Status2018
- Author(s)
  Kamimura Kenya、Yokoo Takeshi、Terai Shuji
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 11 Pages: 3415-3415
- DOI
  10.3390/ijms19113415
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-16K19333
[Journal Article] Effect of histidine on sorafenib-induced vascular damage: Analysis using novel medaka fish model.2018
- Author(s)
  Shinagawa-Kobayashi Y, Kamimura K, Goto R, Ogawa K, Inoue R, Yokoo T, Sakai N, Nagoya T, Sakamaki A, Abe S, Sugitani S, Yanagi M, Fujisawa K, Nozawa Y, Koyama N, Nishina H, Furutani- Seiki M, Sakaida I, Terai S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 496 Issue: 2 Pages: 556-561
- DOI
  10.1016/j.bbrc.2018.01.057
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19701, KAKENHI-PUBLICLY-16H01643, KAKENHI-PUBLICLY-17H05769, KAKENHI-PROJECT-17H04043, KAKENHI-PROJECT-16K15424, KAKENHI-PROJECT-17K09408, KAKENHI-PLANNED-26114005
[Journal Article] Effect of a neural relay on liver regeneration in mice: activation of serotonin release from the gastrointestinal tract2018
- Author(s)
  Inoue Ryosuke、Kamimura Kenya、Nagoya Takuro、Sakai Norihiro、Yokoo Takeshi、Goto Ryo、Ogawa Kohei、Shinagawa-Kobayashi Yoko、Watanabe-Mori Yukari、Sakamaki Akira、Abe Satoshi、Kamimura Hiroteru、Miyamura Norio、Nishina Hiroshi、Terai Shuji
- Journal Title
  
  FEBS Open Bio
  
  Volume: 8 Issue: 3 Pages: 449-460
- DOI
  10.1002/2211-5463.12382
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H06691, KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-18K19537, KAKENHI-PLANNED-26114005
[Journal Article] 臨床応用可能な肝臓選択的核酸医薬送達法の確立2018
- Author(s)
  上村顕也、横尾健、寺井崇二
- Journal Title
  
  BIO Clinica
  
  Volume: 33 Pages: 34-38
- NAID
  40021797767
- Data Source
  KAKENHI-PROJECT-16K19333
[Journal Article] Effective prevention of sorafenib-induced hand–foot syndrome by dried-bonito broth2018
- Author(s)
  Kamimura Kenya、Shinagawa-Kobayashi Yoko、Goto Ryo、Ogawa Kohei、Yokoo Takeshi、Sakamaki Akira、Abe Satoshi、Kamimura Hiroteru、Suda Takeshi、Baba Hiroshi、Tanaka Takayuki、Nozawa Yoshizu、Koyama Naoto、Takamura Masaaki、Kawai Hirokazu、Yamagiwa Satoshi、Aoyagi Yutaka、Terai Shuji
- Journal Title
  
  Cancer Management and Research
  
  Volume: Volume 10 Pages: 805-813
- DOI
  10.2147/cmar.s159370
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09408
[Journal Article] Renal Impairment in Chronic Hepatitis B: A Review2018
- Author(s)
  Kamimura Hiroteru、Setsu Toru、Kimura Naruhiro、Yokoo Takeshi、Sakamaki Akira、Kamimura Kenya、Tsuchiya Atsunori、Takamura Masaaki、Yamagiwa Satoshi、Terai Shuji
- Journal Title
  
  Diseases
  
  Volume: 6 Issue: 2 Pages: 52-52
- DOI
  10.3390/diseases6020052
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-17H06691
[Journal Article] Tumor markers for early diagnosis for brain metastasis of hepatocellular carcinoma: A case series and literature review for effective loco-regional treatment2017
- Author(s)
  Kamimura Kenya、Kobayashi Yuji、Takahashi Yoshifumi、Abe Hiroyuki、Kumaki Daisuke、Yokoo Takeshi、Kamimura Hiroteru、Sakai Norihiro、Sakamaki Akira、Abe Satoshi、Takamura Masaaki、Kawai Hirokazu、Yamagiwa Satoshi、Terai Shuji
- Journal Title
  
  Cancer Biology & Therapy
  
  Volume: 18 Issue: 2 Pages: 79-84
- DOI
  10.1080/15384047.2016.1276134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09408
[Journal Article] Transhepatic arterial infusion chemotherapy using a combination of miriplatin and CDDP powder versus miriplatin alone in the treatment of hepatocellular carcinoma: a randomized controlled trial2017
- Author(s)
  Kamimura Kenya、Suda Takeshi、Yokoo Takeshi、Kamimura Hiroteru、Kanefuji Tsutomu、Tsuchiya Atsunori、Takamura Masaaki、Kawai Hirokazu、Waguri Nobuo、Yamagiwa Satoshi、Terai Shuji
- Journal Title
  
  BMC Cancer
  
  Volume: 17 Issue: 1 Pages: 322-322
- DOI
  10.1186/s12885-017-3320-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09408
[Journal Article] Efficacy and safety of pancreas-targeted hydrodynamic gene delivery in rats.2017
- Author(s)
  Ogawa K, Kamimura K (contributed equally and corresponding), Kobayashi Y, Abe H, Yokoo T, Sakai N, Nagoya T, Sakamaki A, Abe S, Hayashi K, Ikarashi S, Kohisa J, Tsuchida M, Aoyagi Y, Zhang G, Liu D, Terai S.
- Journal Title
  
  Mol Ther Nucleic Acids.
  
  Volume: 9 Pages: 80-88
- DOI
  10.1016/j.omtn.2017.08.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09408, KAKENHI-PROJECT-16K19333
[Journal Article] Effects of fibrotic tissue on liver-targeted hydrodynamic gene delivery.2016
- Author(s)
  Kobayashi Y, Kamimura K, Abe H, Yokoo T, Ogawa K, Shinagawa Y, Goto R, Inoue R, Ohtsuka M, Miura H, Kanefuji T, Suda T, Tsuchida M, Aoyagi Y, Zhang G, Liu D, Terai S.
- Journal Title
  
  Mol Ther Nucleic Acids
  
  Volume: . 5: e359. Pages: 1-8
- DOI
  10.1038/mtna.2016.63
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-26860354, KAKENHI-PROJECT-15K10235, KAKENHI-PROJECT-16K19333
[Journal Article] The Liver-targeted Hydrodynamic Gene Therapy: Recent Advances in the Technique.2016
- Author(s)
  Yokoo T, Kamimura K, Abe H, Kobayashi Y, Kanefuji T, Ogawa K, Goto R, Suda T, Oda M, and Terai S.
- Journal Title
  
  World J Gastroenterol
  
  Volume: 22: Issue: 40 Pages: 8862-8868
- DOI
  10.3748/wjg.v22.i40.8862
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293175, KAKENHI-PROJECT-26860354, KAKENHI-PROJECT-16K19333
[Presentation] CAPに基づき診断したMetabolic dysfunction-associated fatty liver diseaseの臨床的特徴2020
- Author(s)
  横尾健、高村昌昭、寺井崇二
- Organizer
  第43回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-19K08417
[Presentation] 健診スクリーニングを意識した肝発癌リスク評価におけるFIB-4 indexの有用性2020
- Author(s)
  横尾健、高村昌昭、寺井崇二
- Organizer
  第56回日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-19K08417
[Presentation] ALBI score/gradeからみたNASH薬物治療に対する肝予備能への影響2020
- Author(s)
  高村昌昭、横尾健、寺井崇二
- Organizer
  第24回日本肝臓学会大会
- Data Source
  KAKENHI-PROJECT-19K08417
[Presentation] 肝硬変合併肝癌への遺伝子治療確立に向けた方法論の検討2017
- Author(s)
  上村顕也、横尾健、阿部寛幸、小林雄司、小川光平、品川陽子、井上良介、酒井規裕、名古屋卓郎、山際　訓、寺井崇二
- Organizer
  第59回日本消化器病学会大会
- Data Source
  KAKENHI-PROJECT-17K09408
[Presentation] Development of Safe and Effective Hydrodynamic Gene Therapy for Liver Diseases - Effects of Fibrotic Tissue on Gene Delivery Efficiency2017
- Author(s)
  Kenya Kamimura, Yuji Kobayashi, Hiroyuki Abe, Takeshi Yokoo, Masao Ohtsuka, Hiromi Miura, Guisheng Zhang, Dexi Liu, Shuji Terai
- Organizer
  第23回日本遺伝子細胞治療学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19333
[Presentation] 肝硬変合併肝癌への遺伝子治療確立に向けた方法論の検討2017
- Author(s)
  上村顕也, 横尾健, 阿部寛幸, 小林雄司, 小川光平, 品川陽子, 酒井規裕, 坂牧僚, 阿部聡司, 山際訓, 寺井崇二
- Organizer
  JDDW 2017
- Data Source
  KAKENHI-PROJECT-16K19333
[Presentation] Development of Safe and Effective Hydrodynamic Gene Therapy for Liver Diseases - Effects of Fibrotic Tissue on Gene Delivery Efficiency2017
- Author(s)
  Kenya Kamimura1, Yuji Kobayashi1, Hiroyuki Abe1, Takeshi Yokoo1, Masato Ohtsuka2,3, Hiromi Miura4, Guisheng Zhang5, Dexi Liu5, and Shuji Terai1
- Organizer
  第23回日本遺伝子治療学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09408
[Presentation] 臓器特異的ハイドロダイナミック遺伝子導入法による肝疾患の遺伝子治療2016
- Author(s)
  上村顕也、横尾健、阿部寛幸、小林雄司、大塚正人、三浦浩美、小川光平、品川陽子、井上良介、山際訓、寺井崇二
- Organizer
  第102回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル (東京都新宿区)
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16K19333
[Presentation] MMP13遺伝子導入による肝線維化抑制効果2016
- Author(s)
  横尾　健、上村顕也、寺井崇二
- Organizer
  第52回日本肝臓学会総会
- Place of Presentation
  東京ベイ幕張ホール (千葉県千葉市)
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K19333
[Presentation] Therapeutic Effect of Liver-targeted Hydrodynamic Delivery of MMP13 Gene on Liver Fibrosis2016
- Author(s)
  Kenya Kamimura, Hiroyuki Abe, Yuji Kobayashi, Takeshi Yokoo, Masato Ohtsuka, Hiromi Miura, Satoshi Yamagiwa, Shuji Terai
- Organizer
  22nd Annual Meeting of JSGCT 2016（日本遺伝子治療学会）
- Place of Presentation
  虎ノ門ヒルズ (東京都港区)
- Year and Date
  2016-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19333
[Presentation] Development of Image-guided, Liver Lobe-specific Hydrodynamic Gene Delivery Method for Gene Therapy in Liver Diseases2016
- Author(s)
  Kenya Kamimura, Takeshi Yokoo, Shuji Terai, et al
- Organizer
  AASLD 2016
- Place of Presentation
  Boston, USA
- Year and Date
  2016-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19333

1. Terai Shuji (00332809)

# of Collaborated Projects: 8 results

# of Collaborated Products: 37 results
2. Kamimura Kenya (00579146)

# of Collaborated Projects: 7 results

# of Collaborated Products: 32 results
3. 坂牧僚 (40792289)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
4. Takamura Masaaki (20422602)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
5. 土屋淳紀 (70464005)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 大塚正人 (90372945)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
7. Hashimoto Satoru (10768667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 佐藤裕樹 (50644556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 薛徹 (40837184)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 五十嵐聡 (50790953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 仁科博史 (60212122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 三浦浩美 (90599523)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OGAWA kohei

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. KOBAYASHI yoko

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
15. OBA yoshihiko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. YOSHINO hideyoshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ODA masafumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Liu Dexi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. YAMAMOTO Naoki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. FUJISAWA Koichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. UENO Masaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 上村博輝

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
23. 清木誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 高見太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

yokoo takeshi 横尾 健

Yokoo Takeshi 横尾 健

Research Projects

Research Products

Co-Researchers

Development of Organ- and Cell-specific In Vivo Genome Editing Technique as a Novel Approach for Cancer Gene Therapy

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遺伝子導入によるラット胆管癌モデルの確立と浸潤能評価による病態マーカー開発

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Development of Hydrodynamics-based Gene Therapy for the Pancreatic Cancer

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肝発癌におけるCCNDBP1とDNA損傷チェックポイント機構の関連性の解明Principal Investigator

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Efficacy of mesenchymal stem cell for prevention of esophageal stricture after endoscopic submucosal dissection

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Mechanisms of extrahepatic complications in NAFLD/NASH with focus on exosomes

Principal Investigator

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Development of a treatment to improve fibrosis and elucidation of carcinogenesis mechanisms in improved NASH model MC4RKO mice

Principal Investigator

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Research Institution

肝臓特異的ハイドロダイナミック法による核酸医薬送達と肝癌遺伝子治療法への応用

Principal Investigator

Project Period (FY)

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Development of gene therapy for liver cirrhosis utilizing MMP13Principal Investigator

Principal Investigator

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[Book] Nucleic acid-based therapy: Development of a non-viral-based delivery approach in In Vivo and Ex Vivo Gene Therapy for Inherited and Non-Inherited Disorders2019

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[Journal Article] Similarity of oncogenic protein expression in KRAS gene delivery-based rat pancreatic cancer model to that of human pancreatic cancer2023

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[Journal Article] Longitudinal increase in albumin?bilirubin score is associated with non-malignancy-related mortality and quality of life in patients with liver cirrhosis2022

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[Journal Article] Effects of a novel selective PPARα modulator, statin, sodium-glucose cotransporter 2 inhibitor, and combinatorial therapy on the liver and vasculature of medaka nonalcoholic steatohepatitis model2022

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[Journal Article] Cyclin D1 Binding Protein 1 Responds to DNA Damage through the ATM / CHK2 Pathway2022

yokoo takeshi 横尾健

Yokoo Takeshi 横尾健