KOBAYASHI NAOKI 小林直樹

… Alternative Names

Kobayashi Naoki 小林直樹

Less

Researcher Number	80750728
Affiliation (Current)	2023: 国立研究開発法人国立国際医療研究センター, その他部局等, 上級研究員
Affiliation (based on the past Project Information) *help	2017 – 2021: 国立研究開発法人国立国際医療研究センター, その他部局等, 上級研究員 2018: 国立国際医療研究センター, 上級研究員
Review Section/Research Field	Principal Investigator Basic Section 49010:Pathological biochemistry-related Except Principal Investigator Metabolomics / Pathological medical chemistry
Keywords	Principal Investigator インスリン抵抗性 / インスリン分泌 / FGF21 / アクチビン / 糖尿病 / シグナル伝達 / 生理活性 / ヘパトカイン Except Principal Investigator 糖尿病 / 老化 … More / シグナル伝達 / インスリン抵抗性 / 膵β細胞 / MEK/ERKシグナル / 2型糖尿病 / インスリン / 細胞増殖 / 肥満 / 膵島 / Mek/Erkシグナル / インスリン分泌 / Mek/Erk経路 Less

Activin B signaling controls energy homeostasisPrincipal Investigator
- Principal Investigator
  
  Kobayashi Naoki
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  National Center for Global Health and Medicine
Role of MEK/ERK signaling in pancreatic beta cells - to develop a novel treatment strategy for type 2 diaetes
- Principal Investigator
  
  Ikushima Yoshiko M
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  National Center for Global Health and Medicine
Development of a novel anti-aging strategy by elucidating the mechanisms regulating aging through a muscle centric organ network
- Principal Investigator
  
  Ueki Kohjiro
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Metabolomics
- Research Institution
  The University of Tokyo

All 2020 2019 2018

All Journal Article Presentation

[Journal Article] Insulin and lipopolysaccharide mediated signaling in adipose tissue macrophages regulates postprandial glycemia through Akt-mTOR activation2020
- Author(s)
  Toda G、Soeda K、Okazaki Y、Kobayashi N、Masuda Y、Arakawa N、Suwanai H、Masamoto Y、Izumida Y、Kamei N、Sasako T、Suzuki R、Kubota T、Kubota N、Kurokawa M、Tobe K、Noda T、Honda K、Accili D、Yamauchi T、Kadowaki T、Ueki K
- Journal Title
  
  Molecular Cell
  
  Volume: 79 Pages: 1-2
- DOI
  10.1016/j.molcel.2020.04.033
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07898, KAKENHI-PROJECT-19K08991, KAKENHI-PROJECT-19K17954, KAKENHI-PROJECT-18H04052, KAKENHI-PROJECT-19H01052, KAKENHI-PROJECT-17K00846, KAKENHI-PROJECT-18K15075
[Journal Article] The RNA methyltransferase complex of WTAP, METTL3, and METTL14 regulates mitotic clonal expansion in adipogenesis.2019
- Author(s)
  Kobayashi M, Ohsugi M, Sasako T, Awazawa M, Umehara T, Iwane A, Kobayashi N, Okazaki Y, Kubota N, Suzuki R, Waki H, Horiuchi K, Hamakubo T, Kodama T, Aoe S, Tobe K, Kadowaki T, Ueki　K
- Journal Title
  
  Gastrointest. Tumors
  
  Volume: 38 Pages: 81-91
- DOI
  10.1128/mcb.00116-18
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19556, KAKENHI-PROJECT-18K15075, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-16K09776, KAKENHI-PROJECT-17K09819, KAKENHI-PROJECT-26000012, KAKENHI-PROJECT-18H02860
[Journal Article] CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors.2018
- Author(s)
  Nawaz Allah, , Usui Isao, , et al
- Journal Title
  
  Nat Commun.
  
  Volume: 8 Pages: 286-286
- DOI
  10.1038/s41467-017-00231-1
- NAID
  120006535075
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09777, KAKENHI-PROJECT-17K08653, KAKENHI-PROJECT-17K09821, KAKENHI-PROJECT-15H05789, KAKENHI-PROJECT-15H04851, KAKENHI-PROJECT-17H04062, KAKENHI-PROJECT-15K08527
[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2020
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2020
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第34回日本糖尿病・肥満動物学会
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2020
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第24回アディポサイエンスシンポジウム
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2020
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第40回日本肥満学会
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] Activin B-Fstl3による代謝制御機構とその破綻による代謝異常2019
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第33回糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] Activin B - Fstl3 による代謝制御機構とその破綻による代謝異常2019
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] 膵β細胞制御におけるMek/Erkシグナルの役割の解明2019
- Author(s)
  生島芳子，小林直樹，粟澤元晴，諏訪内浩紹，添田光太郎，村谷匡史，高橋倫子，植木浩二郎
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] Mek/Erkシグナルは膵β細胞の量と分泌能を制御する2019
- Author(s)
  生島芳子、小林直樹、粟澤元晴、竹宮聖一、諏訪内浩紹、添田光太郎、守本祐一、村谷匡史、高橋倫子、植木浩二郎
- Organizer
  第33日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] 糖尿病合併 NASH における血糖とインスリンによる腸内細菌叢の変化2019
- Author(s)
  添田光太郎，小林直樹，生島芳子，笹子敬洋，戸田郷太郎，粟澤元晴，門脇孝，植木浩二郎
- Organizer
  第33日本糖尿病・肥満動物学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2019
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第40回日本肥満学会
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] Activin B - Fstl3 Axis Regulates Glucose Metabolism2019
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2019
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第24回アディポサイエンスシンポジウム
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] 心筋におけるAktの役割の解明2018
- Author(s)
  添田光太郎，小林直樹，生島芳子，戸田郷太郎，笹子敬洋，竹宮聖一，野田哲生，門脇孝，植木浩二郎
- Organizer
  第 61 回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-16K19067
[Presentation] Activin B-Fstl3による代謝制御機構とその破綻による代謝異常2018
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第33回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] Hepatic Activin B controls glucose metabolism2018
- Author(s)
  Naoki Kobayashi, Yukiko Okazaki, Takashi Kadowaki, Kohjiro Ueki
- Organizer
  39th JASSO, APDO SYMPOSIUM 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15075
[Presentation] Activin B - Fstl3による代謝制御機構とその破綻による代謝異常2018
- Author(s)
  小林直樹、岡崎由希子、門脇孝、植木浩二郎
- Organizer
  第61回日本糖尿病学会年次学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K15075

1. Ueki Kohjiro (00396714)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. Ikushima Yoshiko M (00571366)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
3. Awazawa Motoharu (90466764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. Suwanai Hirotsugu (60624939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. Muratani Masafumi (50730199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 笹子敬洋 (20550429)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. SUZUKI Ryo

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
8. KUBOTA Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. IZUMIDA Yoshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. USUI Isao

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. FUJISAKA Shiho

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. MATSUMOTO Michihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. NAGAI Yoshinori

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. Kadowaki Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
15. KOBAYASHI Masatoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 戸田郷太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 山内敏正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 中川崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 戸辺一之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 笹原正清

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 窪田直人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOBAYASHI NAOKI 小林 直樹

Kobayashi Naoki 小林 直樹

Research Projects

Research Products

Co-Researchers

Activin B signaling controls energy homeostasisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of MEK/ERK signaling in pancreatic beta cells - to develop a novel treatment strategy for type 2 diaetes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of a novel anti-aging strategy by elucidating the mechanisms regulating aging through a muscle centric organ network

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Insulin and lipopolysaccharide mediated signaling in adipose tissue macrophages regulates postprandial glycemia through Akt-mTOR activation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The RNA methyltransferase complex of WTAP, METTL3, and METTL14 regulates mitotic clonal expansion in adipogenesis.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors.2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2020

Author(s)

Organizer

Data Source

[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2020

Author(s)

Organizer

Data Source

[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2020

Author(s)

Organizer

Data Source

[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2020

Author(s)

Organizer

Data Source

[Presentation] Activin B-Fstl3による代謝制御機構とその破綻による代謝異常2019

Author(s)

Organizer

Data Source

[Presentation] Activin B - Fstl3 による代謝制御機構とその破綻による代謝異常2019

Author(s)

Organizer

Data Source

[Presentation] 膵β細胞制御におけるMek/Erkシグナルの役割の解明2019

Author(s)

Organizer

Data Source

[Presentation] Mek/Erkシグナルは膵β細胞の量と分泌能を制御する2019

Author(s)

Organizer

Data Source

[Presentation] 糖尿病合併 NASH における血糖とインスリンによる腸内細菌叢の変化2019

Author(s)

Organizer

Data Source

[Presentation] Activin B による肥満モデルにおける脂肪組織に対する効果2019

Author(s)

Organizer

Data Source

[Presentation] Activin B - Fstl3 Axis Regulates Glucose Metabolism2019

KOBAYASHI NAOKI 小林直樹

Kobayashi Naoki 小林直樹