Doi Naoya 土肥直哉

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DOI Naoya 土肥直哉

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Researcher Number	80754217
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 技術補佐員
Affiliation (based on the past Project Information) *help	2021 – 2024: 徳島大学, 大学院医歯薬学研究部(医学域), 助教
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related
Keywords	Principal Investigator PIM / HIV / ウイルス粒子産生 / ウイルス遺伝子発現 / 複製制御 / PIM阻害剤 / 翻訳 / 転写 / HIV-2 / ウイルス産生 / HIV-1 / 粒子産生 / 遺伝子発現

PIMキナーゼのタイプ特異的な遺伝子発現制御によるHIV粒子産生抑制機構の解析Principal Investigator
- Principal Investigator
  
  土肥直哉
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  The University of Tokushima
Analysis on the HIV type-specific alteration in viral infectivity by PIM kinase inhibitorsPrincipal Investigator
- Principal Investigator
  
  DOI Naoya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  The University of Tokushima

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] HIV-1 replication and pathogenicity: lessons from macaque-tropic HIV-1 derivatives2023
- Author(s)
  Koma Takaaki、Doi Naoya、Quoc Le Bao、Kondo Tomoyuki、Adachi Akio、Nomaguchi Masako
- Journal Title
  
  IntechOpen
  
  Volume: ー
- DOI
  10.5772/intechopen.1002899
- ISBN
  9780854664672, 9780854664665
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07042, KAKENHI-PROJECT-21K08491
[Journal Article] Involvement of a Rarely Used Splicing SD2b Site in the Regulation of HIV-1 vif mRNA Production as Revealed by a Growth-Adaptive Mutation2023
- Author(s)
  Koma Takaaki、Doi Naoya、Le Bao Quoc、Kondo Tomoyuki、Ishizue Mitsuki、Tokaji Chiaki、Tsukada Chizuko、Adachi Akio、Nomaguchi Masako
- Journal Title
  
  Viruses
  
  Volume: 15 Issue: 12 Pages: 2424-2424
- DOI
  10.3390/v15122424
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07042, KAKENHI-PROJECT-21K08491
[Journal Article] Humanized mice generated by intra-bone marrow injection of CD133-positive hematopoietic stem cells: application to HIV-1 research2023
- Author(s)
  Koma Takaaki、Odaka Tokifumi、Lee Sung-Il、Doi Naoya、Kondo Tomoyuki、Okuma Kazu、Fujisawa Jun-Ichi、Adachi Akio、Nomaguchi Masako
- Journal Title
  
  Frontiers in Virology
  
  Volume: 3 Pages: 1192184-1192184
- DOI
  10.3389/fviro.2023.1192184
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07042, KAKENHI-PROJECT-21K08491
[Journal Article] Major target for UV-induced complete loss of HIV-1 infectivity: A model study of single-stranded RNA enveloped viruses2022
- Author(s)
  Koma Takaaki、Doi Naoya、Suzuki Akihiro、Nagamatsu Kentaro、Yasui Takeshi、Yasutomo Koji、Adachi Akio、Minamikawa Takeo、Nomaguchi Masako
- Journal Title
  
  Frontiers in Virology
  
  Volume: 2
- DOI
  10.3389/fviro.2022.994842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07042, KAKENHI-PROJECT-21K08491
[Journal Article] The Expression Level of HIV-1 Vif Is Optimized by Nucleotide Changes in the Genomic SA1D2prox Region during the Viral Adaptation Process2021
- Author(s)
  Koma Takaaki、Doi Naoya、Takemoto Mai、Watanabe Kyosuke、Yamamoto Hideki、Nakashima Satoshi、Adachi Akio、Nomaguchi Masako
- Journal Title
  
  Viruses
  
  Volume: 13 Issue: 10 Pages: 2079-2079
- DOI
  10.3390/v13102079
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07042, KAKENHI-PROJECT-21K08491
[Journal Article] Species-Specific Valid Ternary Interactions of HIV-1 Env-gp120, CD4, and CCR5 as Revealed by an Adaptive Single-Amino Acid Substitution at the V3 Loop Tip2021
- Author(s)
  Koma Takaaki、Yokoyama Masaru、Kotani Osamu、Doi Naoya、Nakanishi Nina、Okubo Hayato、Adachi Shun、Adachi Akio、Sato Hironori、Nomaguchi Masako
- Journal Title
  
  Journal of Virology
  
  Volume: 95 Issue: 13
- DOI
  10.1128/jvi.02177-20
- NAID
  120007178460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K07042, KAKENHI-PROJECT-21K08491
[Presentation] PIMキナーゼによるウイルス産生抑制の解析2023
- Author(s)
  土肥直哉、駒貴明、Le Quoc Bao、薦田奈々子、一ノ宮匠海、近藤智之、足立昭夫、野間口雅子
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] R5指向性HIV-1複製におけるV3内ITI tripletモティーフの重要性2023
- Author(s)
  Le Quoc Bao、横山勝、土肥直哉、一ノ宮匠海、薦田奈々子、近藤智之、足立昭夫、小谷治、佐藤裕徳、野間口雅子、駒貴明
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] Vpr領域内の同義1塩基置換がHIV-1複製に及ぼす影響2023
- Author(s)
  近藤智之、駒貴明、土肥直哉、Le Quoc Bao、薦田奈々子、一ノ宮匠海、足立昭夫、野間口雅子
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] HIV-1集合におけるGag-NCとgRNAの相互作用の意義2023
- Author(s)
  駒貴明、Le Quoc Bao、土肥直哉、薦田奈々子、一ノ宮匠海、近藤智之、足立昭夫、野間口雅子
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] 未知のHIV-1 Gag二量体化制御単位の同定と構造生物学的性質決定2022
- Author(s)
  小谷治、駒貴明、神庭圭佑、森田泰基、横山勝、土肥直哉、近藤智之、永田崇、足立昭夫、片平正人、野間口雅子、佐藤裕徳
- Organizer
  日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] HIV-1遺伝子発現におけるvpr塩基配列の重要性2022
- Author(s)
  土肥直哉、駒貴明、後藤田知里、長坂麻里、近藤智之、足立昭夫、野間口雅子
- Organizer
  日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] PIMによるHIV種特異的な遺伝子発現制御機構の解析2022
- Author(s)
  近藤智之、駒貴明、宇田川明郁、奥村希、足立昭夫、野間口雅子、土肥直哉
- Organizer
  日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] HIV-1 Gag-MAにおけるGag前駆体二量体化部位のウイルス学的解析2022
- Author(s)
  駒貴明、小谷治、土肥直哉、近藤智之、横山勝、足立昭夫、佐藤裕徳、野間口雅子
- Organizer
  日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] HIV-1 Gag MAのGag二量体化における役割の解明2022
- Author(s)
  駒貴明、小谷治、土肥直哉、近藤智之、横山勝、足立昭夫、佐藤裕徳、野間口雅子
- Organizer
  日本エイズ学会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] PIMキナーゼによるHIV型特異的な遺伝子発現調節の解析2022
- Author(s)
  近藤智之、駒貴明、足立昭夫、野間口雅子、土肥直哉
- Organizer
  日本エイズ学会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] HIV-1 vpr塩基配列の同義一塩基置換がウイルス複製に与える影響2021
- Author(s)
  駒貴明, 土肥直哉, 塚田知寿子, 戸梶智耀、礎光希, 足立昭夫, 野間口雅子
- Organizer
  第68回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-21K08491
[Presentation] PIMキナーゼ阻害剤がHIV種特異的に複製に及ぼす影響の解析2021
- Author(s)
  駒貴明, 礎光希, 塚田知寿子, 戸梶智耀, 足立昭夫, 野間口雅子, 土肥直哉
- Organizer
  第35回日本エイズ学会学術集会・総会
- Data Source
  KAKENHI-PROJECT-21K08491

1. 野間口雅子 (80452647)

# of Collaborated Projects: 2 results

# of Collaborated Products: 18 results

Doi Naoya 土肥 直哉

DOI Naoya 土肥 直哉

Research Projects

Research Products

Co-Researchers

PIMキナーゼのタイプ特異的な遺伝子発現制御によるHIV粒子産生抑制機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis on the HIV type-specific alteration in viral infectivity by PIM kinase inhibitorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] HIV-1 replication and pathogenicity: lessons from macaque-tropic HIV-1 derivatives2023

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Involvement of a Rarely Used Splicing SD2b Site in the Regulation of HIV-1 vif mRNA Production as Revealed by a Growth-Adaptive Mutation2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Humanized mice generated by intra-bone marrow injection of CD133-positive hematopoietic stem cells: application to HIV-1 research2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Major target for UV-induced complete loss of HIV-1 infectivity: A model study of single-stranded RNA enveloped viruses2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Expression Level of HIV-1 Vif Is Optimized by Nucleotide Changes in the Genomic SA1D2prox Region during the Viral Adaptation Process2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Species-Specific Valid Ternary Interactions of HIV-1 Env-gp120, CD4, and CCR5 as Revealed by an Adaptive Single-Amino Acid Substitution at the V3 Loop Tip2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] PIMキナーゼによるウイルス産生抑制の解析2023

Author(s)

Organizer

Data Source

[Presentation] R5指向性HIV-1複製におけるV3内ITI tripletモティーフの重要性2023

Author(s)

Organizer

Data Source

[Presentation] Vpr領域内の同義1塩基置換がHIV-1複製に及ぼす影響2023

Author(s)

Organizer

Data Source

[Presentation] HIV-1集合におけるGag-NCとgRNAの相互作用の意義2023

Author(s)

Organizer

Data Source

[Presentation] 未知のHIV-1 Gag二量体化制御単位の同定と構造生物学的性質決定2022

Author(s)

Organizer

Data Source

[Presentation] HIV-1遺伝子発現におけるvpr塩基配列の重要性2022

Author(s)

Organizer

Data Source

[Presentation] PIMによるHIV種特異的な遺伝子発現制御機構の解析2022

Author(s)

Organizer

Data Source

[Presentation] HIV-1 Gag-MAにおけるGag前駆体二量体化部位のウイルス学的解析2022

Author(s)

Organizer

Doi Naoya 土肥直哉

DOI Naoya 土肥直哉