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Kubota Shigehisa  窪田 成寿

ORCIDConnect your ORCID iD *help
Researcher Number 80759118
Other IDs
Affiliation (Current) 2023: 滋賀医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2020 – 2022: 滋賀医科大学, 医学部, 助教
2018 – 2019: 滋賀医科大学, 医学部, 医員
2017: 滋賀医科大学, 医学部, 非常勤講師
Review Section/Research Field
Principal Investigator
Urology / Basic Section 56030:Urology-related
Except Principal Investigator
Basic Section 56030:Urology-related
Keywords
Principal Investigator
γ-グルタミルシクロトランスフェラーゼ / γ-グルタミルシクロトランスフェラーぜ / トランスクリプトーム解析 / メタボローム解析 / 抗腫瘍メカニズム / 癌関連タンパク / 細胞周期関連遺伝子 / 増殖抑制機構 / がん増殖関連たんぱく / 新規治療標的 … More / 腎がん / がん増殖関連タンパク / GGCT / 腎細胞がん … More
Except Principal Investigator
悪液質 / 癌 / γ-グルタミルシクロトランスフェラーゼ / グルタチオン / 抗がん治療 Less
  • Research Projects

    (4 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (15 People)
  •  脳内炎症に着目した泌尿器癌悪液質の新規診断・治療法の開発

    • Principal Investigator
      沖中 勇輝
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Shiga University of Medical Science
  •  抗癌標的分子GGCT阻害によるグルタチオン関連分子変動の網羅的解明

    • Principal Investigator
      影山 進
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Shiga University of Medical Science
  •  がん増殖関連蛋白GGCTを標的とした腎がんに対する新規治療の開発Principal Investigator

    • Principal Investigator
      窪田 成寿
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56030:Urology-related
    • Research Institution
      Shiga University of Medical Science
  •  Elucidation of the mechanism of antitumor effect in inhibition of GGCT expression using integrated omics analysisPrincipal Investigator

    • Principal Investigator
      Kubota Shigehisa
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Shiga University of Medical Science

All 2021 2019

All Journal Article Presentation

  • [Journal Article] Single Short Retention Instillation of Pirarubicin Prevents Intravesical Recurrence of Low-risk Non Muscle Invasive Bladder Cancer2021

    • Author(s)
      Susumu Kageyama, koki Maeda, Shigehisa Kubota, Tetsuya Yoshida, Takashi Osafune, Yutaka Arai, Hiroki Soga, Zenkai Nishikawa, Yuji Sano, Keita Takimoto, Chul Jang Kim, Tokuhiro Chano, Akihiro Kawauchi
    • Journal Title

      In Vivo

      Volume: 35 Pages: 1141-1145

    • DOI

      10.21873/invivo.12360

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09687, KAKENHI-PROJECT-18K09192, KAKENHI-PROJECT-19K07413, KAKENHI-PROJECT-21K09342
  • [Journal Article] γ-Glutamylcyclotransferase, a novel regulator of HIF-1α expression, triggers aerobic glycolysis.2021

    • Author(s)
      Taniguchi Keiko、Kageyama Susumu、Moyama Chiami、Ando Shota、Ii Hiromi、Ashihara Eishi、Horinaka Mano、Sakai Toshiyuki、Kubota Shigehisa、Kawauchi Akihiro、Nakata Susumu
    • Journal Title

      Cancer Gene Ther

      Volume: - Pages: 37-48

    • DOI

      10.1038/s41417-020-00287-0

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K07623, KAKENHI-PROJECT-20K23233, KAKENHI-ORGANIZER-17H06391, KAKENHI-PLANNED-17H06398, KAKENHI-PROJECT-19H01079, KAKENHI-PROJECT-19H03889, KAKENHI-PROJECT-19K22773, KAKENHI-PROJECT-21K09342
  • [Journal Article] Pro-GA, a Novel Inhibitor of γ-Glutamylcyclotransferase, Suppresses Human Bladder Cancer Cell Growth2019

    • Author(s)
      HANADA EIKI、KAGEYAMA SUSUMU、MURAI RYOSUKE、KUBOTA SHIGEHISA、II HIROMI、NAKATA SUSUMU、KITA HIROKO、KAWAUCHI AKIHIRO、CHANO TOKUHIRO
    • Journal Title

      Anticancer Res.

      Volume: 39 Pages: 1893-1898

    • DOI

      10.21873/anticanres.13297

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K09192, KAKENHI-PROJECT-19K07413, KAKENHI-PROJECT-17K11131
  • [Presentation] オミックス解析に基づくGGCT発現阻害による抗腫瘍メカニズムの解明と膀胱癌治療への応用2021

    • Author(s)
      窪田成寿、礒野高敬, 吉田哲也, 影山 進, 成田充弘, 河内明宏
    • Organizer
      第109回日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-21K09342
  • [Presentation] GGCTを治療標的とした尿路上皮癌治療の基礎的検討2019

    • Author(s)
      影山 進, 窪田 成寿, 村井 亮介, 吉田 哲也, 成田 充弘, 茶野 徳宏, 河内 明宏
    • Organizer
      日本泌尿器科学会総会
    • Data Source
      KAKENHI-PROJECT-17K11131
  • 1.  影山 進 (50378452)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 2.  河内 明宏 (90240952)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 3.  吉田 哲也 (60510310)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  礒野 高敬 (20176259)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  沖中 勇輝 (90780718)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  永澤 誠之 (30750525)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  富田 圭司 (30640148)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  茶野 徳宏 (40346028)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  草場 拓人 (90847211)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  HORINAKA Mano
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  金 哲将
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  中田 晋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  谷口 恵香
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 14.  酒井 敏行
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  村井 亮介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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