Hirofuji Yuta 廣藤雄太

… Alternative Names

広藤雄太ヒロフジユウタ

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Researcher Number	80759746
Affiliation (Current)	2025: 九州大学, 大学病院, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 九州大学, 歯学研究院, 助教 2016: 九州大学, 大学病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 57070:Developmental dentistry-related Except Principal Investigator Orthodontics/Pediatric dentistry / Basic Section 57070:Developmental dentistry-related
Keywords	Principal Investigator ミトコンドリア / Rett症候群 / 乳歯歯髄由来幹細胞 / アンジェルマン症候群 / ヒト乳歯幹細胞 / BDNF / ドーパミン作動性ニューロン / MeCP2 / SHED / 歯髄幹細胞 / ドーパミン作動性神経細胞 / レット症候群 … More Except Principal Investigator … More 歯髄幹細胞 / ヒト脱落乳歯由来幹細胞 / ミトコンドリア / 幹細胞 / 細胞分化 / トランスレーショナルリサーチ / ダウン症候群 / 乳歯由来幹細胞 / ゲノム編集 / ダウン症 / 葉酸 / 酸化ストレス / 口唇裂口蓋裂 Less

患児由来の乳歯幹細胞を用いたアンジェルマン症候群の病態解明研究Principal Investigator
- Principal Investigator
  
  廣藤雄太
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu University
Investigation of pathogenesis and development of novel therapies focusing on mitochondrial function in Rett syndromePrincipal Investigator
- Principal Investigator
  
  Hirofuji Yuta
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu University
Elucidation of the mitochondrial activity regulation linked to the conversion from cell proliferation to differentiation
- Principal Investigator
  
  Kato Hiroki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu University
Elucidation of pathophysiology and development of drug discovery platform using human deciduous tooth-derived stem cells to Rett syndromePrincipal Investigator
- Principal Investigator
  
  Hirofuji Yuta
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Kyushu University
Oxidative stress as an onset mechanism for cleft lip and palate and a possible target for the development of preventive methods
- Principal Investigator
  
  Kato Hiroki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Kyushu University
Translational research to overcome chromosomal abnormality using deciduous teeth
- Principal Investigator
  
  Nonaka Kazuaki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Kyushu University

All 2022 2021 2019 2017

All Journal Article Presentation

[Journal Article] Dopamine-related oxidative stress and mitochondrial dysfunction in dopaminergic neurons differentiated from deciduous teeth-derived stem cells of children with Down syndrome2022
- Author(s)
  Xiao Sun,Hiroki Kato,Hiroshi Sato,Xu Han,Yuta Hirofuji,Takahiro A. Kato,Yasunari Sakai,Shouichi Ohga,Satoshi Fukumoto,Keiji Masuda
- Journal Title
  
  FASEB BioAdvances
  
  Volume: - Issue: 7 Pages: 454-467
- DOI
  10.1096/fba.2021-00086
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10387, KAKENHI-PROJECT-19K10406, KAKENHI-PROJECT-21K17163
[Journal Article] Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency2022
- Author(s)
  Sun Xiao、Dong Shuangshan、Kato Hiroki、Kong Jun、Ito Yosuke、Hirofuji Yuta、Sato Hiroshi、Kato Takahiro A.、Sakai Yasunari、Ohga Shouichi、Fukumoto Satoshi、Masuda Keiji
- Journal Title
  
  Antioxidants
  
  Volume: 11 Issue: 7 Pages: 1361-1361
- DOI
  10.3390/antiox11071361
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K17163
[Journal Article] Impaired neurite development and mitochondrial dysfunction associated with calcium accumulation in dopaminergic neurons differentiated from the dental pulp stem cells of a patient with metatropic dysplasia2021
- Author(s)
  Xiao Sun, Hiroki Kato, Hiroshi Sato, Michiko Torio, Xu Han, Yu Zhang, Yuta Hirofuji, Takahiro A. Kato, Yasunari Sakai, Shouichi Ohga, Satoshi Fukumoto, Keiji Masuda
- Journal Title
  
  Biochem Biophys Rep.
  
  Volume: 26 Pages: 00-00
- DOI
  10.1016/j.bbrep.2021.100968
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10387, KAKENHI-PROJECT-19K08281, KAKENHI-PROJECT-21K17163
[Journal Article] Dental Pulp-Derived Mesenchymal Stem Cells for Modeling Genetic Disorders2021
- Author(s)
  Keiji Masuda, Xu Han, Hiroki Kato, Hiroshi Sato, Yu Zhang, Xiao Sun, Yuta Hirofuji, Haruyoshi Yamaza, Aya Yamada, Satoshi Fukumoto
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22 Issue: 5 Pages: 00-00
- DOI
  10.3390/ijms22052269
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10387, KAKENHI-PROJECT-20K20612, KAKENHI-PROJECT-21K17163
[Journal Article] Folic acid-mediated mitochondrial activation for protection against oxidative stress in human dental pulp stem cells derived from deciduous teeth2019
- Author(s)
  Zhang Yu、Kato Hiroki、Sato Hiroshi、Yamaza Haruyoshi、Hirofuji Yuta、Han Xu、Masuda Keiji、Nonaka Kazuaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 508 Issue: 3 Pages: 850-856
- DOI
  10.1016/j.bbrc.2018.11.169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11807
[Journal Article] Engineering of Systematic Elimination of a Targeted Chromosome in Human Cells.2017
- Author(s)
  Sato H, Kato H, Yamaza H, Masuda K, Nguyen HT, Pham TT, Han X, Hirofuji Y, Nonaka K
- Journal Title
  
  Biomed Res Int
  
  Volume: - Pages: 1-5
- DOI
  10.1155/2017/6037159
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11806, KAKENHI-PROJECT-16K15839
[Journal Article] Direct effects of mitochondrial dysfunction on poor bone health in Leigh syndrome2017
- Author(s)
  Kato Hiroki、Han Xu、Yamaza Haruyoshi、Masuda Keiji、Hirofuji Yuta、Sato Hiroshi、Pham Thanh Thi Mai、Taguchi Tomoaki、Nonaka Kazuaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 493 Issue: 1 Pages: 207-212
- DOI
  10.1016/j.bbrc.2017.09.045
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11806, KAKENHI-PROJECT-16K15839
[Journal Article] Mitochondria Regulate the Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth2017
- Author(s)
  Kato H, Pham TMT, Yamaza H, Masuda K, Hirofuji Y, Han X, Sato H, Taguchi T, Nonaka K.
- Journal Title
  
  Cell Structure and Function
  
  Volume: 42 Pages: 105-116
- NAID
  130005982848
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K15839
[Presentation] ミトコンドリアによる乳歯由来歯髄幹細胞の神経分化制御2017
- Author(s)
  Hiroki Kato, Thanh Thi Mai Pham, Xu Han, Yuta Hirofuji, Haruyoshi Yamaza, Keiji Masuda, Hiroshi Sato, Tomoaki Taguchi, Kazuaki Nonaka
- Organizer
  第69回細胞生物学会大会
- Data Source
  KAKENHI-PROJECT-16K15839
[Presentation] Impairment of Dopaminergic Neuronal Development in Down Syndrome2017
- Author(s)
  Thanh Thi Mai Pham, Haruyoshi Yamaza, Keiji Masuda, Yuta Hirofuji, Kazuaki Nonaka
- Organizer
  第55回日本小児歯科学会大会
- Data Source
  KAKENHI-PROJECT-16K15839
[Presentation] HeLa細胞における21番染色体トリソミーのダイゾミー化2017
- Author(s)
  佐藤浩、加藤大樹、山座治義、増田啓次、Huong Nguyen、Thanh Pham、韓旭、廣藤雄太、野中和明
- Organizer
  2017年度生命科学系学会合同年次会
- Data Source
  KAKENHI-PROJECT-16K15839
[Presentation] Understanding of Neuropathology in Down Syndrome2017
- Author(s)
  Thanh Thi Mai Pham, Hiroki Kato, Haruyoshi Yamaza, Keiji Masuda, Yuta Hirofuji, Hiroshi Sato, Huong Thi Nguyen Nguyen, Tomoaki Taguchi, Kazuaki Nonaka
- Organizer
  The 28th Fukuoka International Symposium on Pediatric/ Maternal-Child Health Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15839

1. Kato Hiroki (30452709)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. 佐藤浩 (00421313)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
3. 増田啓次 (60392122)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. Nonaka Kazuaki (90128067)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. 山座治義 (30336151)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
6. 高山扶美子 (20795950)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. Meno Chikara

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 増田啓二

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
9. 山座孝義

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hirofuji Yuta 廣藤 雄太

広藤 雄太 ヒロフジ ユウタ

Research Projects

Research Products

Co-Researchers

患児由来の乳歯幹細胞を用いたアンジェルマン症候群の病態解明研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of pathogenesis and development of novel therapies focusing on mitochondrial function in Rett syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mitochondrial activity regulation linked to the conversion from cell proliferation to differentiation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of pathophysiology and development of drug discovery platform using human deciduous tooth-derived stem cells to Rett syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Oxidative stress as an onset mechanism for cleft lip and palate and a possible target for the development of preventive methods

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Translational research to overcome chromosomal abnormality using deciduous teeth

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Dopamine-related oxidative stress and mitochondrial dysfunction in dopaminergic neurons differentiated from deciduous teeth-derived stem cells of children with Down syndrome2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitochondrial Calcium-Triggered Oxidative Stress and Developmental Defects in Dopaminergic Neurons Differentiated from Deciduous Teeth-Derived Dental Pulp Stem Cells with MFF Insufficiency2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impaired neurite development and mitochondrial dysfunction associated with calcium accumulation in dopaminergic neurons differentiated from the dental pulp stem cells of a patient with metatropic dysplasia2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dental Pulp-Derived Mesenchymal Stem Cells for Modeling Genetic Disorders2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Folic acid-mediated mitochondrial activation for protection against oxidative stress in human dental pulp stem cells derived from deciduous teeth2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Engineering of Systematic Elimination of a Targeted Chromosome in Human Cells.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Direct effects of mitochondrial dysfunction on poor bone health in Leigh syndrome2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mitochondria Regulate the Differentiation of Stem Cells from Human Exfoliated Deciduous Teeth2017

Author(s)

Journal Title

NAID

Hirofuji Yuta 廣藤雄太

広藤雄太ヒロフジユウタ