Todaka Hiroshi 戸高寛

Researcher Number	80769662
Other IDs
Affiliation (Current)	2023: 高知大学, 教育研究部医療学系基礎医学部門, 助教
Affiliation (based on the past Project Information) *help	2015 – 2022: 高知大学, 教育研究部医療学系基礎医学部門, 助教
Review Section/Research Field	Principal Investigator Cardiovascular medicine / Basic Section 53020:Cardiology-related / Basic Section 49010:Pathological biochemistry-related Except Principal Investigator General medical chemistry / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 虚血性心疾患 / アセチルコリンエステラーゼ / アセチルコリン / 心筋細胞 / 虚血 / 再灌流障害 / AChE / 心筋保護 / 細胞死 / アポトーシス … More / microRNA / ACh / AChE-R / 細胞保護作用 / 虚血ストレス / 細胞保護 / ドネペジル / 筋再生 / 筋萎縮 / 筋ジストロフィー / 抗炎症 … More Except Principal Investigator 筋分化 / 筋再生 / 二本鎖RNA結合蛋白質 / microRNA生合成 / miRNA / 中心核病 / Dynamin 2 / NF90 / NF45 / 中心核 / 骨格筋 / 筋成熟 / マイクロRNA / Dynamin / 筋萎縮 / ミオパチー / Dynamin2 / Sig1R / Sig1Rリガンド / 虚血 / Sigma 1受容体 / 末梢動脈疾患 Less

認知症治療薬のドラッグリポジショニングによる筋ジストロフィーの新規治療法開発Principal Investigator
- Principal Investigator
  
  戸高寛
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Kochi University
Sigma 1受容体リガンドによる末梢動脈疾患に対する新規治療法の開発
- Principal Investigator
  
  野口達哉
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kochi University
Elucidation of the cell protective mechanism of acetylcholinesterase variants in cardiomyocyte and approach to therapy for myocardial infarctionPrincipal Investigator
- Principal Investigator
  
  Todaka Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kochi University
Activation of cardioprotective cholinergic system by miRNA in ischemic heart diseasePrincipal Investigator
- Principal Investigator
  
  TODAKA Hiroshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kochi University
A novel RNA metabolism involved in cell differentiation and survival
- Principal Investigator
  
  Shuji Sakamoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kochi University

All 2022 2021 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation

[Journal Article] Donepezil, an anti-Alzheimer's disease drug, promotes differentiation and regeneration in injured skeletal muscle through the elevation of the expression of myogenic regulatory factors2021
- Author(s)
  Todaka Hiroshi、Arikawa Mikihiko、Noguchi Tatsuya、Ichikawa Atsushi、Sato Takayuki
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 911 Pages: 174528-174528
- DOI
  10.1016/j.ejphar.2021.174528
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06268, KAKENHI-PROJECT-21K08055
[Journal Article] A negative feedback loop between nuclear factor 90 (NF90) and an anti-oncogenic microRNA, miR-7.2019
- Author(s)
  Takuma Higuchi, Keiko Morisawa, Hiroshi Todaka, Sylvia Lai, Eunsup Chi, Kazutsugu Matsukawa, Yasunori Sugiyama, Shuji Sakamoto
- Journal Title
  
  Biochimica et Biophysica Acta
  
  Volume: 503 Pages: 1819-1824
- DOI
  10.1016/j.bbrc.2018.07.119
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06134, KAKENHI-PROJECT-18K15850, KAKENHI-PROJECT-16K08590, KAKENHI-PROJECT-16K19410, KAKENHI-PROJECT-17K15601
[Journal Article] Relationship Between the Fall in Blood Pressure in the Standing Position and Diaphragmatic Muscle Thickness: Proof of Concept Study2019
- Author(s)
  Ichikawa A, Yamasaki F, Ueda M, Todaka H, Miyao E, Yoshinaga Y, Yamanaka S, Matsumura Y, Sato T.
- Journal Title
  
  Blood Press Monit
  
  Volume: 24 Pages: 284-288
- DOI
  10.1097/mbp.0000000000000403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15850
[Journal Article] Candidate plasticity gene 16 mediates suppression of insulin gene expression in rat insulinoma INS-1cells under glucotoxic conditions2019
- Author(s)
  Nakane T, Ido A, Higuchi T, Todaka H, Morisawa K, Nagamine T, Fukunaga K, Sakamoto S, Murao K, Sugiyama Y.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 512 Pages: 189-195
- DOI
  10.1016/j.bbrc.2019.03.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08590, KAKENHI-PROJECT-17K15601, KAKENHI-PROJECT-18K06134, KAKENHI-PROJECT-18K15850, KAKENHI-PROJECT-19K16523
[Journal Article] Suppression of miR-7 biogenesis by NF90-NF45 controls cell proliferation in hepatocellular carcinoma2016
- Author(s)
  Higuchi T, Todaka H, Sugiyama Y, Ono M, Tamaki N, Hatano E, Takezaki Y, Hanazaki K, Miwa T, Chin See LS, Morisawa K, Tsuda M, Taniguchi T, Sakamoto S
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 291 Pages: 21074-21084
- DOI
  10.1074/jbc.m116.748210
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461011, KAKENHI-PROJECT-26750372, KAKENHI-PROJECT-16K08590, KAKENHI-PROJECT-16K19410
[Journal Article] microRNA生合成変動が引き起こす病態生理現象2016
- Author(s)
  戸高寛，樋口琢磨，坂本修士
- Journal Title
  
  比較生理生化学
  
  Volume: 33 Pages: 183-190
- NAID
  130005286662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K19410
[Journal Article] Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.2016
- Author(s)
  Arikawa M, Kakinuma Y, Noguchi T, Todaka H, Sato T.
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 789 Pages: 17-26
- DOI
  10.1016/j.ejphar.2016.06.053
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461059, KAKENHI-PROJECT-16K08560, KAKENHI-PROJECT-16K09441, KAKENHI-PROJECT-16K19410
[Journal Article] Expression and phosphorylation state analysis of intracellular protein kinases using Multi-PK antibody and Phos-tag SDS-PAGE2015
- Author(s)
  Sugiyama, Y., Katayama, S., Kameshita, I., Morisawa, K., Higuchi, T., Todaka, H., Eiji Kinoshita, Kinoshita- Kikuta, E., Koike, T., Taniguchi, T., Sakamoto, S.
- Journal Title
  
  MethodsX
  
  Volume: 2 Pages: 469-474
- DOI
  10.1016/j.mex.2015.11.007
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07887, KAKENHI-PROJECT-26460036, KAKENHI-PROJECT-26750372, KAKENHI-PROJECT-14J07002, KAKENHI-PROJECT-25460371, KAKENHI-PROJECT-25560417, KAKENHI-PROJECT-25293005
[Journal Article] Overexpression of NF90-NF45 complex functions as a negative regulation in the microRNA precessing pathway.2015
- Author(s)
  Todaka H, Higuchi T, Yagyu KI, Sugiyama Y, Yamaguchi F, Morisawa K, Ono M, Fukushima A, Tsuda M, Taniguchi T, Sakamoto S.
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] 認知症治療薬ドネペジルはSigma1受容体を介して筋再生を促進する2022
- Author(s)
  戸高寛, 有川幹彦, 野口達哉, 市川厚, 樋口琢磨,坂本修士, 佐藤隆幸
- Organizer
  第30回日本病態生理学会
- Data Source
  KAKENHI-PROJECT-21K08055
[Presentation] Donepezil, a drug for Alzheimer’s disease, promotes muscle differentiation during the process of regeneration2021
- Author(s)
  Hiroshi Todaka, Mikihiko Arikawa, Tatsuya Noguchi, Atsushi Ichikawa, Takayuki Sato
- Organizer
  the 126th Annual Meeting of The Japanese Association of Anatomists・the 98th Annual Meeting of The Physiological Society of Japan
- Data Source
  KAKENHI-PROJECT-18K15850
[Presentation] Donepezil, anti-Alzheimer drug, enhances myogenesis in C2C12 myoblasts2019
- Author(s)
  Todaka H , Arikawa M , Noguchi T , Ichikawa A , Sato T
- Organizer
  10th International Congress of Comparative Physiology and Biochemistry (ICCPB2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15850
[Presentation] Acetylcholinesterase inhibitor accelerates muscle differentiation in C2C12 myoblasts2019
- Author(s)
  Hiroshi Todaka, Mikihiko Arikawa, Tatsuya Noguchi, Atsushi Ichikawa, Takayuki Sato
- Organizer
  9th FAOPS CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] Acetylcholinesterase inhibitor accelerates muscle differentiation in C2C12 myoblasts2019
- Author(s)
  Hiroshi Todaka, Mikihiko Arikawa, Tatsuya Noguchi, Atsushi Ichikawa, Takayuki Sato
- Organizer
  9th FAOPS CONGRESS
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15850
[Presentation] 神経関連因子Bri3は膵臓β細胞におけるアポトーシスを促進する2019
- Author(s)
  井上楓、中根達人、飯田悟史、戸高寛、樋口琢磨、坂本修士、村尾孝児、杉山康憲
- Organizer
  第60回日本生化学会中国・四国支部会例会
- Data Source
  KAKENHI-PROJECT-18K15850
[Presentation] 骨格筋の分化・成熟化における細胞融合促進因子の新たな発現制御機構2019
- Author(s)
  坂本修士、山口輝、樋口琢磨、森澤啓子、Sylvia Lai、戸高寛、藤田浩志、池恩燮、杉山康憲、松川和嗣、津田雅之
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K15850
[Presentation] 骨格筋の細胞融合及び成熟化におけるRNA結合タンパク質の役割の解明2019
- Author(s)
  坂本修士、山口輝、森澤啓子、樋口琢磨、戸高寛、Sylvia Lai、池恩燮、藤田浩志、杉山康憲、松川和嗣、津田雅之
- Organizer
  日本筋学会　第5回学術集会
- Data Source
  KAKENHI-PROJECT-18K15850
[Presentation] コリンエステラーゼ阻害剤を用いた筋再生機構の解明2018
- Author(s)
  戸高寛, 有川幹彦, 野口達哉, 市川厚, 佐藤隆幸
- Organizer
  第70回日本生理学会中四国地方会
- Data Source
  KAKENHI-PROJECT-18K15850
[Presentation] コリンエステラーゼ阻害剤を用いた筋再生機構の解明2018
- Author(s)
  戸高寛, 有川幹彦, 野口達哉, 市川厚, 佐藤隆幸
- Organizer
  第70回日本生理学会中四国地方会
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 膵臓β細胞におけるCPG16-JDP2を介した新規インスリン発現抑制機構の解明2018
- Author(s)
  中根達人, 井戸彩詠, 樋口琢磨, 戸高寛, 坂本修士, 村尾孝児, 杉山康憲
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15850
[Presentation] Nuclear Factor 90(NF90)の発現はmiR-7を介したフィードバックループにより制御される2018
- Author(s)
  樋口琢磨, 戸高寛, 森澤啓子, Sylvia Lai, 池恩燮, 杉山康憲, 坂本修士
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 膵臓β細胞におけるCPG16-JDP2を介した新規インスリン発現抑制機構の解明2018
- Author(s)
  中根達人, 井戸彩詠, 樋口琢磨, 戸高寛, 坂本修士, 村尾孝児, 杉山康憲
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] Nuclear Factor 90(NF90)の発現はmiR-7を介したフィードバックループにより制御される2018
- Author(s)
  樋口琢磨, 戸高寛, 森澤啓子, Sylvia Lai, 池恩燮, 杉山康憲, 坂本修士
- Organizer
  第91回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-18K15850
[Presentation] 膵臓β細胞におけるコレステロール増加はインスリン発現を抑制する2017
- Author(s)
  藤井修作, 飯田悟史, 戸高寛, 樋口琢磨, 坂本修士, 村尾孝児, 杉山康憲
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 慢性閉塞性肺疾患を示唆する心電図指標2017
- Author(s)
  市川厚, 戸高寛, 山中茂雄, 松村敬久, 佐藤隆幸.
- Organizer
  日本臨床検査自動化学会49回大会
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] マウス心筋梗塞モデルにおいて、心線維芽細胞に認められる非神経性コリン作動系は虚血刺激により活性化する。2017
- Author(s)
  有川幹彦，戸高寛，柿沼由彦，野口達哉，佐藤隆幸
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] Myocardial ischemia-reperfusion elevates the expression of anti-apoptotic acetylcholinesterase.2017
- Author(s)
  戸高寛, 有川幹彦, 市川厚, 野口達哉, 佐藤隆幸
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 骨格筋において過剰発現したNF90-NF45は赤筋化を誘導する2017
- Author(s)
  坂本修士, 森澤啓子, Sylvia Lai, 樋口琢磨, 戸高寛, 池恩燮, 杉山康憲, 津田雅之
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 糖毒性状態の膵臓β細胞において Dclk1はインスリンの発現を抑制する2017
- Author(s)
  井戸彩詠, 樋口琢磨, 戸高寛, 坂本修士, 村尾孝児, 杉山康憲
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 虚血誘導性アポトーシスは心アセチルコリンエステラーゼの発現量を増加させる。2017
- Author(s)
  戸高寛，有川幹彦，市川厚，野口達哉，佐藤隆幸
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松（静岡県浜松市）
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 二本鎖RNA結合タンパク質NF90-NF45の発現増加は生体における造腫瘍能を上昇させる2016
- Author(s)
  樋口琢磨, 三輪武司, 延本篤也, 森澤啓子, Sylvia Chin See Lai, 池恩燮, 戸高寛, 杉山康憲, 津田雅之, 坂本修士
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 造腫瘍能における二本鎖RNA結合蛋白質複合体NF90-NF45の影響2016
- Author(s)
  樋口琢磨, 戸高寛, 三輪武司, 森澤啓子, Sylvia Lai Chin See, 小野正文, 杉山康憲, 津田雅之, 坂本修士.
- Organizer
  第57回日本生化学会中国・四国支部例会
- Place of Presentation
  高知大学（高知県南国市）
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] がん部におけるmiRNAを介したNF90-NF45の発現制御2016
- Author(s)
  樋口琢磨, 森澤啓子, Lai Sylvia Chin See, 三輪武司, 池恩燮, 戸高寛, 杉山康憲, 津田雅之, 坂本修士
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] Elucidation of the role of the doublestranded RNA binding protein NF90-NF45 complex in muscular regeneration.2016
- Author(s)
  Hiroshi Todaka, Takuma Higuchi, Keiko Morisawa, Takeshi Miwa, Lai Sylvia Chin See, Masayuki Tsuda, Yasunori Sugiyama, Mikihiko Arikawa, Takayuki Sato, Shuji Sakamoto.
- Organizer
  RNA2016, THE RNA SOCIETY OF JAPAN 18TH ANNUAL MEETING AND THE 21st ANNUAL MEETHING OF THE RNA SOCIETY.
- Place of Presentation
  The International Conference Center in Kyoto（Kyoto, Japan）
- Year and Date
  2016-06-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 慢性的な高グルコースによるインスリン分泌細胞INS-1内のコレステロールの増加はインスリン発現の障害を誘導する2016
- Author(s)
  藤井修作, 戸高寛, 樋口琢磨, 坂本修士, 村尾孝児, 杉山康憲
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 膵臓ランゲルハンス島におけるRNA結合タンパク質が有する新たな細胞制御作用2016
- Author(s)
  LAI SYLVIA CHIN SEE, 樋口琢磨, 杉山康憲, 森澤啓子, 三輪武司, 戸高寛, 津田雅之, 坂本修士
- Organizer
  第57回日本生化学会中国・四国支部例会
- Place of Presentation
  高知大学（高知県南国市）
- Year and Date
  2016-05-27
- Data Source
  KAKENHI-PROJECT-16K19410
[Presentation] 過剰発現したNF90-NF45複合体は筋サテライト細胞発生のマスター因子であるPax7の発現増加を引き起こす.2015
- Author(s)
  戸高寛, 樋口琢磨, 三輪武司, 森澤啓子, Lai Sylvia Chin See, 有川幹彦, 佐藤隆幸, 津田雅之, 坂本修士.
- Organizer
  Biochemistry and Molecular Biology 2015
- Place of Presentation
  神戸ポートアイランド (神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] 膵臓における二本鎖RNA結合タンパク質NF90及びNF45の機能解析.2015
- Author(s)
  2. Lai Sylvia Chin See, 樋口琢磨, 杉山康憲, 森澤啓子, 戸高寛, 三輪武司, 津田雅之, 坂本修士.
- Organizer
  Biochemistry and Molecular Biology 2015
- Place of Presentation
  神戸ポートアイランド (神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] 抗がん剤を処理したヒト白血病細胞HL-60の細胞内キナーゼの発現およびリン酸化動態の解析.2015
- Author(s)
  杉山康憲, 片山将一, 亀下勇, 森澤啓子, 樋口琢磨, 戸高寛, 木下英司, 木下-菊田恵美子, 小池透, 坂本修士.
- Organizer
  Biochemistry and Molecular Biology 2015
- Place of Presentation
  神戸ポートアイランド (神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] 肝細胞癌における二本鎖RNA結合タンパク質によるケモカイン，CXCL5の発現制御機構.2015
- Author(s)
  三輪武司, 樋口琢磨, 戸高寛, 森澤啓子, Lai Sylvia Chin See, 坂本修士.
- Organizer
  Biochemistry and Molecular Biology 2015
- Place of Presentation
  神戸ポートアイランド (神戸市)
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] NF90-NF45 complex impairs muscular maturation via blockade of miR-133 biogenesis.2013
- Author(s)
  Todaka H, Higuchi T, Yagyu K, Yamaguchi F, Morisawa K, Fukushima A, Tsuda M, Sugiyama Y, Sakamoto S.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド (神戸)
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] Overexpression of NF90-NF45 complex causes centronuclear muscle fibers through blockade of microRNA biogenesis.2013
- Author(s)
  Todaka H, Higuchi T, Yagyu K, Yamaguchi F, Morisawa K, Fukushima A, Tsuda M, Sugiyama Y, Sakamoto S.
- Organizer
  第15回RNA学会年会
- Place of Presentation
  愛媛県県民文化会館ひめぎんホール (愛媛)
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] NF90及びNF45によるmiRNA-7生合成阻害を介した腫瘍化制御機構の解明2013
- Author(s)
  樋口琢磨, 戸高寛, 池恩秀, 山口史佳, 森澤啓子, 小野正文, 杉山康憲, 津田雅之, 坂本修士, 谷口武利.
- Organizer
  第54回日本生化学会中国・四国支部例会
- Place of Presentation
  徳島大学大塚講堂 (徳島)
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] NF90-NF45 regulates an expression of EGFR through suppression of miR-7 biogenesis in hepatocellular carcinoma.2013
- Author(s)
  Higuchi T, Todaka H, Morisawa K, Yamaguchi F, Ono M, Sugiyama Y, Tsuda M, Sakamoto S.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド (神戸)
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] Suppression of miR-7 biogenesis by NF90-NF45 complex in Hepatocellular Carcinoma.2013
- Author(s)
  Higuchi T, Todaka H, Yamaguchi F, Morisawa K, Ono M, Sugiyama Y, Tsuda M, Sakamoto S.
- Organizer
  第15回RNA学会年会
- Place of Presentation
  愛媛県県民文化会館ひめぎんホール (愛媛)
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] Identification of a motif in NF90 protein that is involved in inhibition of microRNA biogenesis.2013
- Author(s)
  Yamaguchi F, Todaka H, Higuchi T, Morisawa K, Sugiyama Y, Sakamoto S.
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド (神戸)
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] NF90-NF45複合体によるmiRNA産生調節を介した筋成熟抑制2013
- Author(s)
  戸高寛, 樋口琢磨, 矢生健一, 森澤啓子, 山口史佳, 池恩秀, 福島敦樹, 津田雅之, 杉山康憲, 坂本修士.
- Organizer
  第54回日本生化学会中国・四国支部例会
- Place of Presentation
  徳島大学大塚講堂 (徳島)
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] マルチPK抗体とPhos-tagを利用した細胞内リン酸化シグナリング解析法
- Author(s)
  杉山康憲, 森澤啓子, 樋口琢磨, 戸高寛, 山口史佳, 安東徳子, 坂本修士.
- Organizer
  第87回日本生化学会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460371
[Presentation] 二本鎖RNA結合タンパク質が関与する肝細胞癌の新たな遊走能制御
- Author(s)
  樋口琢磨, 安東徳子, 三輪武司, 戸高寛, 森澤啓子, Lai Chin See Sylvia, 杉山康憲, 津田雅之, 坂本修士.
- Organizer
  第87回日本生化学会
- Place of Presentation
  国立京都国際会館（京都市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25460371

1. Shuji Sakamoto (80397546)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
2. Higuchi Takuma (10754567)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
3. 野口達哉 (50566495)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. Tsuda Masayuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 小野正文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 杉山康憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 木下恵美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 小池透

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 木下英司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 有川幹彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 柿沼由彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Todaka Hiroshi 戸高 寛

Research Projects

Research Products

Co-Researchers

認知症治療薬のドラッグリポジショニングによる筋ジストロフィーの新規治療法開発Principal Investigator

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Sigma 1受容体リガンドによる末梢動脈疾患に対する新規治療法の開発

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Research Institution

Elucidation of the cell protective mechanism of acetylcholinesterase variants in cardiomyocyte and approach to therapy for myocardial infarctionPrincipal Investigator

Principal Investigator

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Review Section

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Activation of cardioprotective cholinergic system by miRNA in ischemic heart diseasePrincipal Investigator

Principal Investigator

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Research Institution

A novel RNA metabolism involved in cell differentiation and survival

Principal Investigator

Project Period (FY)

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Research Institution

[Journal Article] Donepezil, an anti-Alzheimer's disease drug, promotes differentiation and regeneration in injured skeletal muscle through the elevation of the expression of myogenic regulatory factors2021

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[Journal Article] A negative feedback loop between nuclear factor 90 (NF90) and an anti-oncogenic microRNA, miR-7.2019

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[Journal Article] Relationship Between the Fall in Blood Pressure in the Standing Position and Diaphragmatic Muscle Thickness: Proof of Concept Study2019

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[Journal Article] Candidate plasticity gene 16 mediates suppression of insulin gene expression in rat insulinoma INS-1cells under glucotoxic conditions2019

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[Journal Article] Suppression of miR-7 biogenesis by NF90-NF45 controls cell proliferation in hepatocellular carcinoma2016

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[Journal Article] microRNA生合成変動が引き起こす病態生理現象2016

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NAID

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[Journal Article] Donepezil, an acetylcholinesterase inhibitor, attenuates LPS-induced inflammatory response in murine macrophage cell line RAW 264.7 through inhibition of nuclear factor kappa B translocation.2016

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DOI

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[Journal Article] Expression and phosphorylation state analysis of intracellular protein kinases using Multi-PK antibody and Phos-tag SDS-PAGE2015

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[Journal Article] Overexpression of NF90-NF45 complex functions as a negative regulation in the microRNA precessing pathway.2015

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[Presentation] 認知症治療薬ドネペジルはSigma1受容体を介して筋再生を促進する2022

Author(s)

Todaka Hiroshi 戸高寛