Chigusa Yoshitsugu 千草義継

Researcher Number	80779158
Affiliation (Current)	2021: 京都大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2017 – 2021: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Obstetrics and gynecology / Basic Section 56040:Obstetrics and gynecology-related Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Basic Section 58070:Lifelong developmental nursing-related / Obstetrics and gynecology / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 早産 / 羊膜 / TLR4 Except Principal Investigator 前期破水 / 羊膜 / マクロファージ / 早産 / 治癒・再生 / 妊娠糖尿病 / placental organoid … More

Establishment of a postpartum care system of gestational diabetes through multidisciplinary collaboration using ICT
- Principal Investigator
  
  原島伸一
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58070:Lifelong developmental nursing-related
- Research Institution
  Kyoto University
自然免疫からみた羊膜の維持・修復機構：前期破水の予防・治療をめざして
- Principal Investigator
  
  最上晴太
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyoto University
The establishment of glycemic management in gestational diabetes mellitus: a new attempt to protect maternal and child health
- Principal Investigator
  
  東真弓
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 58070:Lifelong developmental nursing-related
- Research Institution
  Kyoto University
早産治療を目指した変異EDAの作成Principal Investigator
- Principal Investigator
  
  千草義継
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyoto University
円錐切除後妊娠の腟分泌物プロテオーム解析を用いた子宮頸部が担う妊娠維持機構の解明
- Principal Investigator
  
  近藤英治
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Kyoto University
Healing of ruptured fetal membranes: investigation of the mechanisms and new treatment
- Principal Investigator
  
  Mogami Haruta
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Kyoto University
Three-dimensional human placental buds synthesized from induced pluripotent stem cells for regenerative therapy that can restore placental function
- Principal Investigator
  
  Kondoh Eiji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyoto University
Search for the TLR4 inhibitor as a novel treatment strategy for preterm birthPrincipal Investigator
- Principal Investigator
  
  Chigusa Yoshitsugu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyoto University

All 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Histological distribution pattern of hemosiderin deposition on the chorionic plate and fetal membrane of diffuse chorioamniotic hemosiderosis related to chronic abruption oligohydramnios sequence2021
- Author(s)
  Ishida Ayami、Minamiguchi Sachiko、Yamada Yosuke、Nakagawa Ryota、Chigusa Yoshitsugu、Kondoh Eiji、Mandai Masaki、Haga Hironori
- Journal Title
  
  Placenta
  
  Volume: 105 Pages: 1-6
- DOI
  10.1016/j.placenta.2021.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09801
[Journal Article] Cushing’s syndrome during pregnancy with different clinical courses: Two case reports2020
- Author(s)
  Umemiya Maki、Chigusa Yoshitsugu、Minamiguchi Sachiko、Horie Akihito、Mandai Masaki、Kondoh Eiji
- Journal Title
  
  Hypertens Res Pregnancy
  
  Volume: N/A Issue: 1 Pages: 26-30
- DOI
  10.14390/jsshp.hrp2019-019
  10.14390/jsshp.HRP2019-019
- ISSN
  2187-5987, 2187-9931
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09801
[Journal Article] New era of trophoblast research: integrating morphological and molecular approaches2020
- Author(s)
  Io Shingo、Kondoh Eiji、Chigusa Yoshitsugu、Kawasaki Kaoru、Mandai Masaki、Yamada and Shigehito
- Journal Title
  
  Human Reproduction Update
  
  Volume: 26 Pages: 611-633
- DOI
  10.1093/humupd/dmaa020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09801, KAKENHI-PROJECT-20K20719
[Journal Article] Mechanisms of thrombin-induced myometrial contractions: Potential targets of progesterone2020
- Author(s)
  Fumitomo Nishimura, Haruta Mogami, Kaori Moriuchi, Yoshitsugu Chigusa, Masaki Mandai, and Eiji Kondoh
- Journal Title
  
  PLOS ONE
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09259
[Journal Article] Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone2020
- Author(s)
  Nishimura Fumitomo、Mogami Haruta、Moriuchi Kaori、Chigusa Yoshitsugu、Mandai Masaki、Kondoh Eiji
- Journal Title
  
  PLOS ONE
  
  Volume: 15 Pages: 0231944-0231944
- DOI
  10.1371/journal.pone.0231944
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09801, KAKENHI-PROJECT-18K09259
[Journal Article] Intracervical elastomeric sealant in an ex vivo model.2019
- Author(s)
  Kondoh E, Kawamura Y, Chigusa Y, Mogami H, Ueda A, Hamanishi J, Mandai M.
- Journal Title
  
  J Matern Fetal Neonatal Med.
  
  Volume: 19 Pages: 1-3
- DOI
  10.1080/14767058.2019.1626367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09801
[Journal Article] Maternal Glucocorticoids Make the Fetal Membrane Thinner: Involvement of Amniotic Macrophages.2019
- Author(s)
  Kiyokawa H, Mogami H, Ueda Y, Kawamura Y, Sato M, Chigusa Y, Mandai M, Kondoh E.
- Journal Title
  
  Endocrinology.
  
  Volume: 160 Pages: 925-937
- DOI
  10.1210/en.2018-01039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09259
[Journal Article] Placental Sonic Hedgehog Pathway Regulates Fetal Growth via the IGF Axis in Preeclampsia2019
- Author(s)
  Takai Hiroshi、Kondoh Eiji、Mogami Haruta、Kawasaki Kaoru、Chigusa Yoshitsugu、Sato Mai、Kawamura Yosuke、Murakami Ryusuke、Matsumura Noriomi、Konishi Ikuo、Mandai Masaki
- Journal Title
  
  The Journal of Clinical Endocrinology & Metabolism
  
  Volume: 104 Pages: 4239-4252
- DOI
  10.1210/jc.2019-00335
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09259
[Journal Article] Metabolomic Profiles of Placenta in Preeclampsia.2019
- Author(s)
  Kawasaki K, Kondoh E, Chigusa Y, Kawamura Y, Mogami H, Takeda S, Horie A, Baba T, Matsumura N, Mandai M, Konishi I.
- Journal Title
  
  Hypertension.
  
  Volume: 73 Pages: 671-679
- DOI
  10.1161/hypertensionaha.118.12389
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09259
[Journal Article] Impaired Wnt5a signaling in extravillous trophoblasts: Relevance to poor placentation in early gestation and subsequent preeclampsia.2018
- Author(s)
  Ujita M, Kondoh E, Chigusa Y, Mogami H, Kawasaki K, Kiyokawa H, Kawamura Y, Takai H, Sato M, Horie A, Baba T, Konishi I, Matsumura N, Mandai M.
- Journal Title
  
  Pregnancy Hypertens.
  
  Volume: 13 Pages: 225-234
- DOI
  10.1016/j.preghy.2018.06.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] 羊膜中のマクロファージはTGF-b1を介した上皮間葉転換により破水部の治癒を促進する2020
- Author(s)
  川村洋介、最上晴太、猪早阿紗子、上田優輔、千草義継、近藤英治、万代昌紀
- Organizer
  第41回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Fetal macrophages in amnion promote the healing of ruptured membranes through TGFb-1-induced epithelial-mesenchymal transition.2020
- Author(s)
  Kawamura, Y, Mogami H, Inohaya A, Ueda Y, Chigusa Y, Kondoh E, and Mandai M.
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Ligustilide inhibits oxytocin-induced human myometrial contraction and alleviates lipopolysaccharide-induced proinflammatory response in human macrophages.2020
- Author(s)
  Ueda Y, Mogami H, Inohaya A, Kawamura, Y, Sato M, Kawasaki K, Chigusa Y, Kondoh E, and Mandai M.
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Glucocorticoid weakens fetal membranes via IL-1β production by amniotic fluid macrophage.2019
- Author(s)
  Hikaru Kiyokawa, Haruta Mogami, Yoshitsugu Chigusa, Eiji Kondoh, Masaki Mandai
- Organizer
  Society for Reproductive Investigation 66th Annual Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] 妊娠中の高用量ステロイドは卵膜を脆弱化する2019
- Author(s)
  最上晴太、清川晶、上田優輔　千草義継、近藤英治、万代昌紀
- Organizer
  第141回近畿産科婦人科学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] 1型コラーゲンは妊娠マウスの前期破水の治癒を促進する2019
- Author(s)
  最上晴太　川村洋介　上田優輔　佐藤麻衣　千草義継　近藤英治　万代昌紀
- Organizer
  第40回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Collagen Type I Gels Stimulates Healing of Ruptured Amnion in Mouse PROM2019
- Author(s)
  Haruta Mogami, Yoshitsugu Chigusa, Eiji Kondoh, Ruth A. Word, and Masaki Mandai
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Ligustilide inhibits oxytocin-induced human myometrial contraction2019
- Author(s)
  Yusuke Ueda, Haruta Mogami, Yoshitsugu Chigusa, Eiji Kondoh, and Masaki Mandai
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Fetal macrophages in amniotic fluid assist the healing of ruptured membranes2019
- Author(s)
  Yosuke Kawamura, Haruta Mogami, Yusuke Ueda, Mai Sato, Yoshitsugu Chigusa, Eiji Kondoh, and Masaki Mandai
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Fetal macrophages in amniotic fluid assist the healing of ruptured membranes2019
- Author(s)
  Yosuke KAWAMURA, Haruta MOGAMI, Yusuke UEDA, Mai SATO, Yoshitsugu CHIGUSA, Eiji KONDOH, Masaki MANDAI
- Organizer
  Society for Reproductive Investigation 66th Annual Scientific Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] 母体グルココルチコイド投与は羊膜マクロファージにより卵膜を脆弱化させる2019
- Author(s)
  清川晶、最上晴太、上田優輔　川村洋介　佐藤麻衣　千草義継、近藤英治、万代昌紀
- Organizer
  第27回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Fetal macrophages in amniotic fluid assist the healing of ruptured membranes2019
- Author(s)
  Yosuke Kawamura, Haruta Mogami, Yusuke Ueda, Mai Sato, Yoshitsugu Chigusa, Eiji Kondoh, and Masaki Mandai
- Organizer
  The Society for Reproductive Investigation, 66th Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Glucocorticoid weakens fetal Mmembranes via IL-1β production by amniotic fluid macrophages2019
- Author(s)
  Hikaru Kiyokawa, Haruta Mogami, Yoshitsugu Chigusa, Eiji Kondoh, and Masaki Mandai
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Glucocorticoid weakens Fetal Membranes via IL-1β Production by Amniotic Fluid Macrophages2019
- Author(s)
  Hikaru Kiyokawa, Haruta Mogami, Yoshitsugu Chigusa, Eiji Kondoh, and Masaki Mandai
- Organizer
  The Society for Reproductive Investigation, 66th Annual meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] 母体グルココルチコイド投与は羊膜マクロファージにより卵膜を脆弱化させる2019
- Author(s)
  清川晶、最上晴太、千草義継、近藤英治、万代昌紀
- Organizer
  第55回日本周産期・新生児医学会総会学術集会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Thrombin Activates Myosin Light Chain and Induces Cyclooxygenase-2 (COX-2) Synthesis in Human Myometrial Cells and Progesterone Blocks Its Pathway2019
- Author(s)
  Fumitomo Nishimura, Haruta Mogami, Yoshitsugu Chigusa, Eiji Kondoh, and Masaki Mandai
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Three-dimensional synthesized human placenta from an iPSC-derived organ bud transplant2019
- Author(s)
  Sato M, Kondoh E, Kawamura Y, Takai H, Chigusa Y, Mogami H, Mandai M
- Organizer
  第71回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-17H04339
[Presentation] 羊水中の胎児肝臓由来マクロファージは破膜部位の卵膜再生を促進する2018
- Author(s)
  川村洋介、最上晴太、上田優輔、佐藤麻衣、千草義継、近藤英治、万代昌紀
- Organizer
  第12回日本早産学会学術集会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Repairing fetal membranes by elastomeric sealant in mouse pPROM model2018
- Author(s)
  Yosuke Kawamura, Haruta Mogami, Mai Sato, Hiroshi Takai, Yoshitsugu Chigusa, Eiji Kondoh, Masaki Mandai
- Organizer
  第70回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Fetal macrophages in amniotic fluid assist the healing of ruptured membranes2018
- Author(s)
  Yosuke Kawamura, Haruta Mogami, Yusuke Ueda, Mai Sato, Yoshitsugu Chigusa, Eiji Kondoh, Masaki Mandai
- Organizer
  2018 International Federation on Placenta Associations (IFPA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09259
[Presentation] Amniotic fluid macrophages help the healing of ruptured amnion via epithelial mesenchymal transition (EMT)2018
- Author(s)
  Haruta Mogami, Yosuke Kawamura, Shingo Io, Mai Sato, Hiroshi Takai, Yoshitsugu Chigusa, Eiji Kondoh, Masaki Mandai, and Ruth Ann Word
- Organizer
  第70回日本産科婦人科学会
- Data Source
  KAKENHI-PROJECT-18K09259

1. Kondoh Eiji (10544950)

# of Collaborated Projects: 5 results

# of Collaborated Products: 31 results
2. Mogami Haruta (40378766)

# of Collaborated Projects: 4 results

# of Collaborated Products: 27 results
3. 原島伸一 (80444793)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 古田真里枝 (20390312)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 西村亜希子 (70738674)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 東真弓 (20447981)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 曽根正勝 (40437207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 山原研一 (50450888)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 万代昌紀 (80283597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 26 results
10. 伊藤慎二 (50362512)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 元木環 (80362424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Word Ruth Ann

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YAMADA Shigehito

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Chigusa Yoshitsugu 千草 義継

Research Projects

Research Products

Co-Researchers

Establishment of a postpartum care system of gestational diabetes through multidisciplinary collaboration using ICT

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自然免疫からみた羊膜の維持・修復機構：前期破水の予防・治療をめざして

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The establishment of glycemic management in gestational diabetes mellitus: a new attempt to protect maternal and child health

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

早産治療を目指した変異EDAの作成Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

円錐切除後妊娠の腟分泌物プロテオーム解析を用いた子宮頸部が担う妊娠維持機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Healing of ruptured fetal membranes: investigation of the mechanisms and new treatment

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Three-dimensional human placental buds synthesized from induced pluripotent stem cells for regenerative therapy that can restore placental function

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Search for the TLR4 inhibitor as a novel treatment strategy for preterm birthPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Histological distribution pattern of hemosiderin deposition on the chorionic plate and fetal membrane of diffuse chorioamniotic hemosiderosis related to chronic abruption oligohydramnios sequence2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cushing’s syndrome during pregnancy with different clinical courses: Two case reports2020

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] New era of trophoblast research: integrating morphological and molecular approaches2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mechanisms of thrombin-induced myometrial contractions: Potential targets of progesterone2020

Author(s)

Journal Title

Data Source

[Journal Article] Mechanisms of thrombin-Induced myometrial contractions: Potential targets of progesterone2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Intracervical elastomeric sealant in an ex vivo model.2019

Author(s)

Chigusa Yoshitsugu 千草義継