Koseki Yoshitaka 小関良卓

Researcher Number	80780634
Other IDs
Affiliation (Current)	2025: 県立広島大学, 生物資源科学部, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2025: 東北大学, 多元物質科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related / Basic Section 37010:Bio-related chemistry Except Principal Investigator Medium-sized Section 35:Polymers, organic materials, and related fields / Basic Section 35030:Organic functional materials-related / Basic Section 56060:Ophthalmology-related / Medium-sized Section 32:Physical chemistry, functional solid state chemistry, and related fields
Keywords	Principal Investigator ドラッグデリバリーシステム / 有機合成 / 抗がん剤 / プロドラッグ / 鉄触媒 / 配位子送達 / 細胞内有機合成 / SN-38 Except Principal Investigator ナノ薬剤 / 抗がん剤 … More / 再沈法 / ドラッグデリバリーシステム / 表面修飾 / 手術 / 瘢痕抑制薬 / 眼圧 / ナノ粒子 / 薬剤開発 / 瘢痕抑制 / 濾過手術 / 緑内障 / 眼科 / 表面分子修飾 / 探針増強ラマン散乱法(TERS) / 銀ナノワイヤー / 探針増強ラマン散乱(TERS) / 化学的表面修飾 / 分子表面修飾 / 探針増強ラマン散乱 / グラフェンナノリボン / グラフェン Less

多重刺激応答型ナノ・プロドラッグの開発Principal Investigator
- Principal Investigator
  
  小関良卓
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tohoku University
タンデム型プロドラッグ活性化によるがん細胞内選択的な薬物治療法の開発Principal Investigator
- Principal Investigator
  
  小関良卓
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tohoku University
がん細胞特有の刺激に応答し薬物を放出する新規抗がん薬ナノ粒子の開発
- Principal Investigator
  
  笠井均
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 35:Polymers, organic materials, and related fields
- Research Institution
  Tohoku University
Development of scarring quantification technology and nanoparticles for inhibition of bleb scarring with high tissue penetration
- Principal Investigator
  
  Tsuda Satoru
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Tohoku University
Intracellular synthesis of anti-cancer agent by ligand delivery cheimstryPrincipal Investigator
- Principal Investigator
  
  Koseki Yoshitaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 37010:Bio-related chemistry
- Research Institution
  Tohoku University
Site-specific chemical adsorption on graphene nanoribbon toward active band-gap engineering
- Principal Investigator
  
  猪瀬朋子
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 32:Physical chemistry, functional solid state chemistry, and related fields
- Research Institution
  Kyoto University
  Hokkaido University
Development of anti-cancer nanodrugs with high drug loading capacity and dispersion stability by surface modification
- Principal Investigator
  
  Kasai Hitoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 35030:Organic functional materials-related
- Research Institution
  Tohoku University

All 2023 2022 2021 2020 2019

All Journal Article Presentation Patent

[Journal Article] Fabrication of anti-inflammatory nano eye-drops composed of dexamethasone prodrugs2023
- Author(s)
  Tanita Keita、Iijima Mai、Koseki Yoshitaka、Sato Kota、Nakazawa Toru、Kasai Hitoshi
- Journal Title
  
  Molecular Crystals and Liquid Crystals
  
  Volume: - Issue: 1 Pages: 1-7
- DOI
  10.1080/15421406.2023.2180212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21J13130, KAKENHI-PROJECT-23K14316, KAKENHI-PROJECT-22H00328
[Journal Article] Label-Free Tracking of Nanoprodrug Cellular Uptake and Metabolism Using Raman and Autofluorescence Imaging2023
- Author(s)
  Machida Masato、Sugimura Toshiki、Kajimoto Shinji、Taemaitree Farsai、Koseki Yoshitaka、Kasai Hitoshi、Nakabayashi Takakazu
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: - Issue: 17 Pages: 3851-3860
- DOI
  10.1021/acs.jpcb.3c01133
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K20524, KAKENHI-PROJECT-23K14316
[Journal Article] Design of guaiazulene derivatives-conjugated podophyllotoxin nano-prodrug toward anticancer drug delivery2022
- Author(s)
  Maruoka Kiyotaka、Koseki Yoshitaka、Dao Anh Thi Ngoc、Suzuki Ryuju、Batbayar Anudari、Sugeno Nagaki、Umezawa Hirohito、Kasai Hitoshi
- Journal Title
  
  Molecular Crystals and Liquid Crystals
  
  Volume: N/A Issue: 1 Pages: 1-9
- DOI
  10.1080/15421406.2022.2056384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-22H00328
[Journal Article] Polymeric functionalization of podophyllotoxin carrier-free drug nanoparticles for enhancing bioavailability and in?vitro cellular imaging2022
- Author(s)
  Taemaitree Farsai、Tamada Masamichi、Koseki Yoshitaka、Onodera Tsunenobu、Oikawa Hidetoshi、Kasai Hitoshi
- Journal Title
  
  Molecular Crystals and Liquid Crystals
  
  Volume: N/A Issue: 1 Pages: 1-7
- DOI
  10.1080/15421406.2022.2052491
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-21J13093
[Journal Article] Conversion of 2,5-Bis(hydroxymethyl)furan to Highly Oxidized Cyclopentenones under Catalyst-free Conditions in Water2022
- Author(s)
  Nakatsuji Hirotaka、Kamishima Takaaki、Nonaka Toshiyuki、Koseki Yoshitaka、Kasai Hitoshi
- Journal Title
  
  Chemistry Letters
  
  Volume: 51 Issue: 5 Pages: 497-499
- DOI
  10.1246/cl.220027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15690
[Journal Article] Development of camptothecin nano-prodrugs based on trimethyl lock groups toward selective drug release in cancer cells2022
- Author(s)
  Shibata Aki、Koseki Yoshitaka、Tanita Keita、Suzuki Ryuju、Dao Anh Thi Ngoc、Kasai Hitoshi
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 103 Pages: 153989-153989
- DOI
  10.1016/j.tetlet.2022.153989
- Data Source
  KAKENHI-PROJECT-22H00328
[Journal Article] Fabrication of size-controlled SN-38 pure drug nanocrystals through an ultrasound-assisted reprecipitation method toward efficient drug delivery for cancer treatment2021
- Author(s)
  Koseki Yoshitaka、Ikuta Yoshikazu、Taemaitree Farsai、Saito Nozomi、Suzuki Ryuju、Dao Anh Thi Ngoc、Onodera Tsunenobu、Oikawa Hidetoshi、Kasai Hitoshi
- Journal Title
  
  Journal of Crystal Growth
  
  Volume: 572 Pages: 126265-126265
- DOI
  10.1016/j.jcrysgro.2021.126265
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19H02785, KAKENHI-PROJECT-21J13093
[Journal Article] Serum Albumin-treated SN-38 Prodrug Nanoparticles toward Cancer Treatment2021
- Author(s)
  Taemaitree Farsai、Koseki Yoshitaka、Dao Anh Thi Ngoc、Kasai Hitoshi
- Journal Title
  
  Chemistry Letters
  
  Volume: 50 Issue: 8 Pages: 1555-1558
- DOI
  10.1246/cl.210253
- NAID
  130008072795
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19H02785, KAKENHI-PROJECT-21J13093
[Journal Article] Organic nanocrystal enrichment in paper microfluidic analysis2021
- Author(s)
  Grasianto、Fukuyama Mao、Mott Derrick M.、Koseki Yoshitaka、Kasai Hitoshi、Hibara Akihide
- Journal Title
  
  Sensors and Actuators B: Chemical
  
  Volume: 333 Pages: 129548-129548
- DOI
  10.1016/j.snb.2021.129548
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-18H03912
[Journal Article] Tropone Skeleton Enhances the Dispersion Stability of Nano-prodrugs2020
- Author(s)
  Tanita Keita、Koseki Yoshitaka、Kamishima Takaaki、Kasai Hitoshi
- Journal Title
  
  Chemistry Letters
  
  Volume: 49 Issue: 3 Pages: 222-224
- DOI
  10.1246/cl.190876
- NAID
  130007805887
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19H02785
[Journal Article] Effect of the chemical structure on the drug release from brinzolamide based nano eye-drops2020
- Author(s)
  Koseki Yoshitaka、Ikuta Yoshikazu、Sato Kota、Aoyagi Shigenobu、Inada Satoshi、Onodera Tsunenobu、Oikawa Hidetoshi、Nishiguchi Koji M.、Nakazawa Toru、Kasai Hitoshi
- Journal Title
  
  Molecular Crystals and Liquid Crystals
  
  Volume: 706 Issue: 1 Pages: 122-128
- DOI
  10.1080/15421406.2020.1743447
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19H02785
[Journal Article] FRET-based intracellular investigation of nanoprodrugs toward highly efficient anticancer drug delivery2020
- Author(s)
  Taemaitree Farsai、Fortuni Beatrice、Koseki Yoshitaka、Fron Eduard、Rocha Susana、Hofkens Johan、Uji-i Hiroshi、Inose Tomoko、Kasai Hitoshi
- Journal Title
  
  Nanoscale
  
  Volume: 12 Issue: 32 Pages: 16710-16715
- DOI
  10.1039/d0nr04910g
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19KK0136, KAKENHI-PROJECT-17H03003, KAKENHI-PROJECT-19H02785
[Journal Article] Self-assemble tannic acid and iron complexes on pure nanodrugs surface prevents aggregation and enhances anticancer drug delivery efficiency2020
- Author(s)
  Taemaitree Farsai、Koseki Yoshitaka、Saito Nozomi、Suzuki Ryuju、Dao Anh Thi Ngoc、Kasai Hitoshi
- Journal Title
  
  Molecular Crystals and Liquid Crystals
  
  Volume: 706 Issue: 1 Pages: 116-121
- DOI
  10.1080/15421406.2020.1743446
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19H02785
[Journal Article] ナノ・プロドラッグ：新たな抗がん薬輸送システムの細胞内挙動2020
- Author(s)
  小関良卓, Farsai Taemaitree, Beatrice Fortuni, Susana Rocha, 雲林院宏, 猪瀬朋子, 笠井均
- Journal Title
  
  細胞
  
  Volume: 52 Pages: 47-51
- Data Source
  KAKENHI-PROJECT-19K15690
[Journal Article] 抗がん治療のための新規DDS製剤ナノ・プロドラッグ2020
- Author(s)
  小関良卓、笠井均
- Journal Title
  
  The Bulletin of the Society of Nano Science and Technology（ナノ学会会報）
  
  Volume: 19 Pages: 15-20
- NAID
  40022381412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15690
[Journal Article] Fabrication of Hinokitiol-modified podophyllotoxin nano-prodrugs having a high drug loading capacity2020
- Author(s)
  Tanita Keita、Koseki Yoshitaka、Shimizu Kazue、Umezawa Hirohito、Kasai Hitoshi
- Journal Title
  
  Molecular Crystals and Liquid Crystals
  
  Volume: 706 Issue: 1 Pages: 79-85
- DOI
  10.1080/15421406.2020.1743441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19H02785
[Journal Article] Influence of Hydrolysis Susceptibility and Hydrophobicity of SN-38 Nano-Prodrugs on Their Anticancer Activity2019
- Author(s)
  Y. Koseki, Y. Ikuta, L. Cong, M. Takano, H. Tada, M. Watanabe, K. Gonda, T. Ishida, N. Ohuchi, K. Tanita, F. Taemaitree, A. T.N. Dao, T. Onodera, H. Oikawa, H. Kasai
- Journal Title
  
  Bull. Chem. Soc. Jpn.
  
  Volume: 92 Issue: 8 Pages: 1305-1313
- DOI
  10.1246/bcsj.20190088
- NAID
  130007689993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19H02785
[Journal Article] Formation of Five-Membered Carbocycles from d-Glucose: A Concise Synthesis of 4-Hydroxy-2-(hydroxymethyl)cyclopentenone2019
- Author(s)
  Y. Koseki, T. Watanabe, T. Kamishima, E. Kwon, H. Kasai
- Journal Title
  
  Bull. Chem. Soc. Jpn.
  
  Volume: 92 Issue: 8 Pages: 1324-1328
- DOI
  10.1246/bcsj.20190063
- NAID
  130007689998
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K03598, KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19H02785
[Journal Article] A facile synthesis of (+)/(－)-pentenomycin I and analogs, and their antimicrobial evaluation.2019
- Author(s)
  Kamishima T, Suzuki M, Aoyagi S, Watanabe T, Koseki Y, Kasai H
- Journal Title
  
  Tetrahedron Letters
  
  Volume: 60(20) Issue: 20 Pages: 1375-1378
- DOI
  10.1016/j.tetlet.2019.04.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08846, KAKENHI-PROJECT-19K15690, KAKENHI-PROJECT-19H02785
[Patent] ＳＮ－３８誘導体、当該誘導体を含むナノ粒子、医薬及び当該ナノ粒子の製造方法2021
- Inventor(s)
  笠井均、谷田恵太、小関良卓
- Industrial Property Rights Holder
  笠井均、谷田恵太、小関良卓
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2021-040799
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K15690
[Patent] 化合物、そのナノ粒子及び癌疾患の治療剤2020
- Inventor(s)
  笠井均、小関良卓
- Industrial Property Rights Holder
  笠井均、小関良卓
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-046717
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Fabrication and drug release properties of prodrug nanopaticles with high cancer selectivity2023
- Author(s)
  Aki Shibata, Yoshitaka Koseki, Keita Tanita, Kiyotaka Maruoka, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14316
[Presentation] 低分子集合型ナノ薬剤の作製とドラッグデリバリーシステムへの応用2023
- Author(s)
  小関良卓
- Organizer
  第50回東北地区高分子若手研究会夏季ゼミナール
- Invited
- Data Source
  KAKENHI-PROJECT-23K14316
[Presentation] Development of glutathione-responsive prodrug with selective drug release in cancerous sites2023
- Author(s)
  Ikuma Saitoh, Yoshitaka Koseki, Aki Shibata, Ryuju Suzuki, Hitoshi Kasai
- Organizer
  International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14316
[Presentation] サイズ制御された薬剤ナノ粒子の作製と抗がん活性評価2023
- Author(s)
  小関良卓
- Organizer
  2023年度第1回粉体操作に伴う諸現象に関する勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-23K14316
[Presentation] ビオチン修飾リポソームにより被覆されたプロドラッグナノ粒子の作製およびその能動的ターゲティング能の評価2023
- Author(s)
  數井武藏, ファーサイテエーマイトリイ, ベアトリスフォルトゥーニ, 小関良卓, ダオアンティンゴック, 鈴木龍樹, 雲林院宏, 笠井均
- Organizer
  日本化学会第103春季年会(2023)
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] がん細胞内のグルタチオンにより選択的に活性化されるSN-38プロドラッグナノ粒子の開発2023
- Author(s)
  水谷明日香, 柴田暁貴, 谷田恵太, 鈴木龍樹, Anh Dao, 小関良卓, 笠井均
- Organizer
  日本化学会第103春季年会(2023)
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] Development of near-Infrared light-responsive nano prodrug@hydrogel for locoregional therapy2023
- Author(s)
  Zhixiang Liu, Anh T. N. Dao, Ryuju Suzuki, Yoshitaka Koseki, Hitoshi Kasai
- Organizer
  日本化学会第103春季年会(2023)
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] Development of SN-38 prodrug nanoparticles with selective activation by intracellular specific enzymes that cleave s-s bonds in cancer cells2023
- Author(s)
  Asuka Mizutani, Aki Shibata, Keita Tanita, Ryuju Suzuki, Anh Thi Ngoc Dao, Yoshitaka Koseki, Hitoshi Kasai
- Organizer
  International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K14316
[Presentation] がん細胞選択的な薬物放出性を指向したプロドラッグナノ粒子の創製2023
- Author(s)
  柴田暁貴, 小関良卓, 谷田恵太, 鈴木龍樹, Anh Thi Ngoc Dao, 笠井均
- Organizer
  日本化学会第103春季年会(2023)
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] 有機ナノ粒子の細胞内溶解過程を追跡できる高発光性ナノ粒子の開発2022
- Author(s)
  三木佑太郎, Farsai Taemaitree, 鈴木龍樹, 小関良卓, Anh Dao, 橋本塁人, 若宮淳志, 笠井均
- Organizer
  日本化学会第102春季年会(2022)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] 3級エステルを有するプロドラッグの合成とそのナノ粒子の抗がん活性評価2022
- Author(s)
  柴田暁貴, 小関良卓, 谷田恵太, 鈴木龍樹, Anh Thi Ngoc Dao, 笠井均
- Organizer
  日本化学会第102春季年会(2022
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] がん細胞内でのみ薬物を放出する新規薬剤ナノ粒子の作製と薬効評価2022
- Author(s)
  谷田恵太, 小関良卓, 鈴木龍樹, アンダオ, 笠井均
- Organizer
  日本化学会第102春季年会(2022)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] 疎水性プロドラッグナノ粒子の生体内安定性の向上を目指したアポリポタンパク質（apo-AI)による修飾2022
- Author(s)
  程偉, 中辻博貴, 小関良卓, AnhDAO, 鈴木龍樹, 村上達也, 笠井均
- Organizer
  令和4年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] Liposomal modification of SN-38 Nano-Prodrugs and Evaluation of their Cellular Uptake2022
- Author(s)
  數井武藏, ファーサイテエーマイトリイ, ベアトリスフォルトゥーニ, 小関良卓, ダオアンティンゴック, 鈴木龍樹, 雲林院宏, 笠井均
- Organizer
  令和4年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] がん細胞内でのみ薬物を放出する新規薬剤ナノ粒子の作製と薬効評価2022
- Author(s)
  谷田恵太, 小関良卓, 鈴木龍樹, アンダオ, 笠井均
- Organizer
  日本化学会第102春季年会(2022
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Effectively drug release from camptothecin nano-prodrugs with sterically hindered esters derived from tertiary hydroxy groups2022
- Author(s)
  Aki Shibata, Yoshitaka Koseki, Keita Tanita, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  KJF-ICOMEP 2022
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] Development of Near-Infrared Light-Responsive Nano-Prodrug@Hydrogel for Locoregional Cancer Therapy2022
- Author(s)
  劉智翔, 小関良卓, 鈴木龍樹, ティンゴックアンダオ, 笠井均
- Organizer
  2022年度高分子学会東北支部研究発表会
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] リポソームにより表面修飾したSN-38ナノ・プロドラッグの作製および抗がん活性評価に関する研究2022
- Author(s)
  數井武藏, Farsai Teamaitree, 小関良卓, Anh Dao, 鈴木龍樹, 笠井均
- Organizer
  日本化学会第102春季年会(2022)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Development of nano-prodrugs@hydrogel materials for locoregional therapy2022
- Author(s)
  Zhixiang Liu, Yoshitaka Koseki, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  日本化学会第102春季年会(2022)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Development of nano-prodrug@hydrogel for locoregional therapy2022
- Author(s)
  劉智翔, 小関良卓, 鈴木龍樹, ティンゴックアンダオ, 笠井均
- Organizer
  令和4年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] Fabrication of injectable silk hydrogel for controlling the release of various anticancer drugs2022
- Author(s)
  Mengheng Yang, Yoshitaka Koseki, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  日本化学会第102春季年会(2022)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Development of Injectable Silk Hydrogels for Targeted Delivery of Nanoprodrugs2022
- Author(s)
  楊孟衡, 小関良卓, 鈴木龍樹, ティンゴックアンダオ, 笠井均
- Organizer
  2022年度高分子学会東北支部研究発表会
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] Development of injectable silk hydrogel loaded with nano-prodrugs for controllable drug release2022
- Author(s)
  楊孟衡, 小関良卓, 鈴木龍樹, ティゴックアンダオ, 笠井均
- Organizer
  令和4年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] 有機ナノ粒子の細胞内溶解過程を追跡できる高発光性ナノ粒子の開発2022
- Author(s)
  三木佑太郎, Farsai Taemaitree, 鈴木龍樹, 小関良卓, Anh Dao, 橋本塁人, 若宮淳志, 笠井均
- Organizer
  日本化学会第102春季年会(2022
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Development of Anticancer Prodrugs Selectively Activated by β-lactamase2022
- Author(s)
  上原満季, 小関良卓, 鈴木龍樹, ティゴックアンダオ, 笠井均
- Organizer
  令和4年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] Fabrication of nano-prodrugs composed of SN-38 dimer that release drugs with high efficiency in cancer cells2022
- Author(s)
  谷田恵太, 小関良卓, 鈴木龍樹, ティンゴックアンダオ, 笠井均
- Organizer
  令和4年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-22H00328
[Presentation] 3級エステルを有するプロドラッグの合成とそのナノ粒子の抗がん活性評価2022
- Author(s)
  柴田暁貴, 小関良卓, 谷田恵太, 鈴木龍樹, Anh Thi Ngoc Dao, 笠井均
- Organizer
  日本化学会第102春季年会(2022)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Intracellular investigation of carrier-free nano-prodrugs toward highly efficient anticancer drug delivery systems2021
- Author(s)
  Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Johan Hofkens, Hiroshi Uji-i, Ryuju Suzuki, Anh Dao, Tomoko Inose, Hitoshi Kasai
- Organizer
  Samaggi Academic Conference and Careers Fair 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication of guaiazulene derivatives nano-prodrugs and their structure-activity evaluation2021
- Author(s)
  Kiyotaka Maruoka, Keita Tanita, Ryuju Suzuki, Yoshitakta Koseki, Toshihiro Murafuji, Hitoshi Kasai
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication of highly fluorescent FRET NPs for the investigation of intracellular behavior2021
- Author(s)
  Yutaro Miki, Farsai Taemaitree, Ryuju Suzuki, Yoshitaka Koseki, Anh T.N. Dao, Ruito Hashimoto, Atsushi Wakamiya, Hitoshi Kasai
- Organizer
  14th International Symposium on Nanomedicine (ISNM2021)
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Design strategy for nano-prodrug with selective and effective activation via tertiary hydroxyl substitution2021
- Author(s)
  Aki Shibata, Yoshitaka Koseki, Keita Tanita, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Pharmacological activity of guaiazulene derivatives-conjugated PPT nano-prodrugs2021
- Author(s)
  Kiyotaka Maruoka, Yoshitaka Koseki, Anh Thi Ngoc Dao, Ryuju Suzuki, Batbayar Anudari, Nagaki Sugeno, Hirohito Umezawa, Hitoshi Kasai
- Organizer
  KJF-ICOMEP2021
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] β-ラクタマーゼにより選択的に活性化される抗がん剤プロドラッグの合成2021
- Author(s)
  上原満季, 小関良卓, 笠井均
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Polymeric Functionalization of Podophyllotoxin Carrier-free Drug Nanoparticles for Enhancing Bioavailability and In Vitro Cellular Imaging2021
- Author(s)
  Farsai Taemaitree, Masamichi Tamada, Yoshitaka Koseki, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai
- Organizer
  KJF-ICOMEP2021
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] チオール基による共有結合形成に基づいたナノ薬剤の表面修飾2021
- Author(s)
  小関良卓
- Organizer
  第8回東北大学若手アンサンブルワークショップ
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Study on syntheses of guaiazulene carboxylic acid derivatives with controlled regiospecific reactivity2021
- Author(s)
  Kiyotaka Maruoka, Takaaki Kamishima, Yoshitaka Koseki, Ryuju Suzuki, Anh Thi Ngoc Dao, Toshihiro Murafuji, Hitoshi Kasai
- Organizer
  令和3年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Development of Fabrication Technique for Drug Nanoparticles toward Efficient Cancer Therapy2021
- Author(s)
  Yoshitaka Koseki, Yoshikazu Ikuta, Farsai Taemaitree, Nozomi Saito, Ryuju Suzuki. Anh Thi, Ngoc Dao, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai
- Organizer
  The 8th Asian Conference on Crystal Growth and Crystal Technology (CGCT-8)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication of nano-prodrugs composed of hinokitiol-modified podophyllotoxin and their anticancer activity2021
- Author(s)
  Keita Tanita, Yoshitaka Koseki, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  令和3年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Fabrication of nano-prodrugs composed of hinokitiol-modified podophyllotoxin2021
- Author(s)
  Keita Tanita, Yoshitaka Koseki, Takaaki Kamishima, Hitoshi Kasai
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Intracellular investigation of carrier-free nano-prodrugs toward highly efficient anticancer drug delivery systems2021
- Author(s)
  Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Johan Hofkens, Hiroshi Uji-i, Ryuju Suzuki, Anh Dao, Tomoko Inose, Hitoshi Kasai
- Organizer
  Samaggi Academic Conference and Careers Fair 2021
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Fabrication of injectable silk hydrogel for controlling the release of various anticancer drugs2021
- Author(s)
  Mengheng Yang, Anh T.N. Dao, Farsai Taemaitree, Ryuju Suzuki, Yoshitaka Koseki, Hitoshi Kasai
- Organizer
  VANJ Conference
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] グアイアズレンの特異的な反応性を制御したカルボン酸誘導体の合成2021
- Author(s)
  丸岡清隆, 神島尭明, 小関良卓, 鈴木龍樹, Anh Thi Ngoc Dao, 村藤俊宏, 笠井均
- Organizer
  第118回有機合成シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] フィルムに担持した薬剤ナノ粒子の抗腫瘍活性評価2021
- Author(s)
  齋藤希望, ファーサイテェーマイトリィ, 鈴木龍樹, 小関良卓, 笠井均
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Development of novel nano-prodrug based on tertiary hydroxyl substitution2021
- Author(s)
  Aki Shibata, Yoshitaka Koseki, Keita Tanita, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  令和3年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] ラマンおよび自家蛍光分光法を用いた生細胞内における薬剤ナノ粒子のラベルフリー動態追跡2021
- Author(s)
  町田雅斗, 杉村俊紀, 小関良卓, 笠井均, 梶本真司, 中林孝和
- Organizer
  第15回分子科学討論会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Development of novel nano-prodrugs via tertiary hydroxyl substituion2021
- Author(s)
  Aki Shibata, Yoshitaka Koseki, Keita Tanita, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  TU-TaipeiTech Online Joint Symposium 2021
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Activity evaluation of a β-Lactamase-Activated Prodrug2021
- Author(s)
  Mitsuki Uehara, Yoshitaka Koseki, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  令和3年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Development of Fabrication Technique for Drug Nanoparticles toward Efficient Cancer Therapy2021
- Author(s)
  Yoshitaka Koseki, Yoshikazu Ikuta, Farsai Taemaitree, Nozomi Saito, Ryuju Suzuki. Anh Thi, Ngoc Dao, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai
- Organizer
  The 8th Asian Conference on Crystal Growth and Crystal Technology
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Polymeric Functionalization of Podophyllotoxin Carrier-free Drug Nanoparticles for Enhancing Bioavailability and In Vitro Cellular Imaging2021
- Author(s)
  Farsai Taemaitree, Masamichi Tamada, Yoshitaka Koseki, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai
- Organizer
  KJF-ICOMEP2021
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Pharmacological activity based on the bonding position of guaiazulene derivative2021
- Author(s)
  Kiyotaka Maruoka, Keita Tanita, Ryuju Suzuki, Anh Thi Ngoc Dao, Yoshitaka Koseki, Toshihiro Murafuji, Hitoshi Kasai
- Organizer
  2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Catalytic Performance of Iron Phthalocyanine Nanoparticles in Aqueous2021
- Author(s)
  Hiroto Kimura, Ryuju Suzuki, Anh T. N. Dao, Yoshitaka Koseki, Hitoshi Kasai
- Organizer
  令和3年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Pharmacological activity of guaiazulene derivatives-conjugated PPT nano-prodrugs2021
- Author(s)
  Kiyotaka Maruoka, Yoshitaka Koseki, Anh Thi Ngoc Dao, Ryuju Suzuki, Batbayar Anudari, Nagaki Sugeno, Hirohito Umezawa, Hitoshi Kasai
- Organizer
  KJF-ICOMEP2021
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Intracellular investigation of SN-38 prodrug nanoparticles as carrier-free anticancer drug delivery systems2021
- Author(s)
  Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Hiroshi Uji-i, Tomoko Inose, Hitoshi Kasai
- Organizer
  2021 International Chemical Congress of Pacific Basin Societies (Pacifichem 2021)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication of highly fluorescent FRET NPs for the investigation of intracellular behavior2021
- Author(s)
  Yutaro Miki, Farsai Taemaitree, Ryuju Suzuki, Yoshitaka Koseki, Anh T.N. Dao, Ruito Hashimoto, Atsushi Wakamiya, Hitoshi Kasai
- Organizer
  14th International Symposium on Nanomedicine (ISNM2021)
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Investigation of SN-38 Anticancer Nano-prodrugs Intracellular Dynamics2021
- Author(s)
  Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Johan Hofkens, Hiroshi Uji-i, Anh Thi Ngoc Dao, Ryuju Suzuki, Tomoko Inose, Hitoshi Kasai
- Organizer
  日本化学会第101春季年会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Intracellular investigation of SN-38 nano-prodrugs toward anticancer drug delivery applications2020
- Author(s)
  Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Hiroshi Uji-I, Johan Hofkens, Anh T. N. Dao, Ryuju Suzuki, Tomoko Inose, Hitoshi Kasai
- Organizer
  東北大学＆理化学研究所連携シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Tracking intracellular dynamics of anticancer nano-prodrugs using Raman imaging2020
- Author(s)
  杉村俊紀, 梶本真司, TaemaitreeFarsai, 小関良卓, 笠井均, 中林孝和
- Organizer
  令和2年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Polymeric engineering of prodrug nanoparticles for the investigation of intracellular drug dynamics2020
- Author(s)
  Farsai Taemaitree, Beatrice Fortuni, Tomoko Inose, Yoshitaka Koseki, Hiroshi Uji-I, Hitoshi Kasai
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication SN-38 Nano-Prodrugs for Anticancer Drug Delivery2020
- Author(s)
  小関良卓, 笠井均
- Organizer
  令和2年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Tracking intracellular dynamics of anticancer nano-prodrugs using Raman imaging2020
- Author(s)
  杉村俊紀, 梶本真司, TaemaitreeFarsai, 小関良卓, 笠井均, 中林孝和
- Organizer
  令和2年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Intracellular investigation of nanoprodrugs towards anticancer drug delivery application2020
- Author(s)
  Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Johan Hofkens, Hiroshi Uji-i, Tomoko Inose, Hitoshi Kasai
- Organizer
  高分子・ハイブリッド材料研究センター 2020 PHyM シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] フィルムに担持した抗がん剤ナノ粒子の再放出挙動と薬効評価2020
- Author(s)
  齋藤希望, ティーマイトリー, ファーサイ, 鈴木龍樹, 小関良卓, 笠井均
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Polymeric engineering of prodrug nanoparticles for the investigation of intracellular drug dynamics2020
- Author(s)
  Farsai Taemaitree, Beatrice Fortuni, Tomoko Inose, Yoshitaka Koseki, Hiroshi Uji-I, Hitoshi Kasai
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Intracellular investigation of nanoprodrugs towards anticancer drug delivery application2020
- Author(s)
  Farsai Taemaitree, Beatrice Fortuni, Yoshitaka Koseki, Eduard Fron, Susana Rocha, Johan Hofkens, Hiroshi Uji-i, Tomoko Inose, Hitoshi Kasai
- Organizer
  2020 PHyM シンポジウム
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] 高分子フィルムへの薬剤ナノ粒子の担持と放出挙動2020
- Author(s)
  齋藤希望、ティーマイトリーファーサイ、鈴木龍樹、小関良卓、笠井均
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Development of nano-prodrugs composed of hinokitiol-modified anticancer drugs2020
- Author(s)
  Keita Tanita, Yoshitaka Koseki, Takaaki Kamishima, Kazue Shimizu, Hirohito Umezawa, Hitoshi Kasai
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] フィルムに担持した抗がん剤ナノ粒子の再放出挙動と薬効評価2020
- Author(s)
  齋藤希望, ティーマイトリー, ファーサイ, 鈴木龍樹, 小関良卓, 笠井均
- Organizer
  第69回高分子学会年次大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Fabrication of guaiazulene derivatives nanoparticles and their pharmacological activity2020
- Author(s)
  Kiyotaka Maruoka, Keita Tanita, Ryuju Suzuki, Yoshitaka Koseki, Hitoshi Kasai
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] グアイアズレン誘導体ナノプロドラッグの作製と薬効特性評価2020
- Author(s)
  丸岡清隆, 谷田恵太, 鈴木龍樹, 小関良卓, 村藤俊宏, 笠井均
- Organizer
  2020 PHyM シンポジウム
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication SN-38 Nano-Prodrugs and Their Anticancer Activity2020
- Author(s)
  Yoshitaka Koseki, Yoshikazu Ikuta, Liman Cong, Mayumi Takano-Kasuya, Hiroshi Tada, Mika Watanabe, Kohsuke Gonda, Takanori Ishida, Noriaki Ohuchi, Keita Tanita, Farsai Taemaitree, Anh Thi Ngoc Dao, Tsunenobu Onodera, Hidetoshi Oikawa, Hitoshi Kasai
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] グアイアズレン誘導体ナノプロドラッグの作製と薬効特性評価2020
- Author(s)
  丸岡清隆, 谷田恵太, 鈴木龍樹, 小関良卓, 村藤俊宏, 笠井均
- Organizer
  高分子・ハイブリッド材料研究センター 2020 PHyM シンポジウム
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Fabrication SN-38 Nano-Prodrugs for Anticancer Drug Delivery2020
- Author(s)
  小関良卓、笠井均
- Organizer
  令和2年度化学系学協会東北大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] 効果的な感染症の治療を目指した再沈法による抗菌剤ナノ粒子の作製2020
- Author(s)
  山内啓大朗、谷田恵太、小関良卓、笠井均
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] SN-38 の DE 環の部分合成2020
- Author(s)
  戸田成美、小関良卓、笠井均
- Organizer
  日本化学会第100春季年会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] METAL ION ENRICHMENT USING ORGANIC NANOCRYSTAL COATED-MICROFLUIDIC2020
- Author(s)
  Grasianto, Mao Fukuyama, Derrick Mott, Yoshitaka Koseki, Hitoshi Kasai, Akihide Hibara
- Organizer
  MicroTAS 2020 Virtual Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Investigation of hydrogen generation mechanism from polyethylene2019
- Author(s)
  Saori Inoue, Anh T. N. Dao, Yoshitaka Koseki, Chika Watanabe, Shingo Ishihara, Junya Kano, Hitoshi Kasai
- Organizer
  Tohoku University's Chemistry Summer School 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication of antimicrobial nanoparticles for the treatment of infectious diseases2019
- Author(s)
  山内啓大朗, 谷田恵太, 小関良卓, 笠井均
- Organizer
  2019年度高分子・ハイブリッド材料研究センター「2019 PHyMシンポジウム」
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Controlled Drug Release from Nano-Prodrugs Based on Linker Carbon Chain Length2019
- Author(s)
  K. Tanita, Y. Koseki, H. Kasai
- Organizer
  2019 KJF International Conference on Organic Materials for Electronics and Photonics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Controlled Drug Release from Nano-Prodrugs Based on Linker Carbon Chain Length2019
- Author(s)
  Keita Tanita, Yoshitaka Koseki, Kazue Shimizu, Hirohito Umezawa, Hitoshi Kasai
- Organizer
  2019 KJF International Conference on Organic Materials for Electronics and Photonics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] リンカーの長さが異なるポドフィロトキシン-ヒノキチオール誘導体の合成とそのナノ・プロドラッグの作製2019
- Author(s)
  谷田恵太、小関良卓、清水和恵、梅澤洋史、笠井均
- Organizer
  第４１回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Effect of serum protein on dispersion stability and anticancer activity of SN-38 nano-prodrugs2019
- Author(s)
  Farsai Taemaitree, Yoshitaka Koseki, Hitoshi Kasai
- Organizer
  The 33rd Conference of the European Colloid and Interface Society (ECIS2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Surface Functionalization of Prodrug Nanoparticles Toward Anticancer Drug Delivery2019
- Author(s)
  Farsai Taemaitree, Yoshitaka Koseki, Ryuju Suzuki, Anh Thi Ngoc Dao, and Hitoshi Kasai
- Organizer
  2nd G'L'owing Polymer Symposium in KANTO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] ポリエチレンの水蒸気改質とそのメカニズム解明2019
- Author(s)
  井上彩織, A. T. N. Dao, 小関良卓, 渡邉千香, 石原真吾, 加納純也, 笠井均
- Organizer
  2019高分子学会東北支部研究発表会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Mechanism study of hydrogen generation from polyethylene in presence of catalysts2019
- Author(s)
  井上彩織,ティゴックアンダオ,小関良卓,渡邉千香,石原真吾,加納純也,笠井均
- Organizer
  令和元年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Mechanism study of hydrogen generation from polyethylene in presence of catalysts2019
- Author(s)
  井上彩織, Anh. T. N. Dao, 小関良卓, 渡邉千香, 石原真吾, 加納純也, 笠井均
- Organizer
  2019年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Fabrication of hinokitiol-modified podophyllotoxin nano-prodrugs and controlling their drug release2019
- Author(s)
  谷田恵太,小関良卓,清水和恵,梅澤洋史,笠井均
- Organizer
  令和元年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Self-Assemble Tannic Acid and Iron Complexes on Nano-Prodrugs Surface Prevents Aggregation and Enhances Anticancer Drug Delivery Efficiency2019
- Author(s)
  Farsai Taemaitree, Yoshitaka Koseki, Nozomi Saito, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  2019 KJF International Conference on Organic Materials for Electronics and Photonics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Effect of serum protein on dispersion stability and anticancer activity of SN-38 nano-prodrugs2019
- Author(s)
  F. Taemaitree, Y. Koseki, H. Kasai
- Organizer
  The 33rd Conference of the European Colloid and Interface Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Tannic acid-modified SN-38 nano-prodrugs toward effective anticancer drug delivery2019
- Author(s)
  N. Saito, F. Taemaitree, Y. Koseki, R. Suzuki, A. T. N. Dao, H. Kasai
- Organizer
  Sendai Albi Knowledge in Engineering Seminars
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Effect of the Structure on the Drug Release from Brinzolamide based Nano Eye-Drops2019
- Author(s)
  Y. Koseki, Y. Ikuta, K. Sato, S. Aoyagi, S. Inada, T. Onodera, H. Oikawa, K. Nishiguchi, T. Nakazawa, H. Kasai
- Organizer
  2019 KJF International Conference on Organic Materials for Electronics and Photonics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Surface Functionalization of Prodrug Nanoparticles Toward Anticancer Drug Delivery2019
- Author(s)
  F. Taemaitree, Y. Koseki, R. Suzuki, A. T. N. Dao, H. Kasai
- Organizer
  2nd G’L’owing Polymer Symposium in KANTO
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] ポリエチレンからの水素発生に置ける反応機構解析2019
- Author(s)
  井上彩織、Anh Thi Ngoc Dao、小関良卓、渡邊千香、石原真吾、加納純也、笠井均
- Organizer
  第１９回東北大学多元物質科学研究所研究発表会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Surface Engineering of Nano-prodrugs for Highly Effective Anticancer Drug Delivery2019
- Author(s)
  F. Taemaitree, Y. Koseki, R. Suzuki, A. T. N. Dao, H. Kasai
- Organizer
  2019高分子学会東北支部研究発表会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] ポリエチレンの水蒸気改質とそのメカニズム解明2019
- Author(s)
  井上彩織、Anh Thi Ngoc Dao、小関良卓、渡邊千香、石原真吾、加納純也、笠井均
- Organizer
  2019高分子学会東北支部研究発表会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Surface Engineering of Nano-prodrugs for Highly Effective Anticancer Drug Delivery2019
- Author(s)
  Farsai Taemaitree, Yoshitaka Koseki, Ryuju Suzuki, Anh Thi Ngoc Dao, and Hitoshi Kasai
- Organizer
  2019高分子学会東北支部研究発表会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication of liposome-coated SN-38 nano-prodrugs2019
- Author(s)
  Keitaro Yamauchi, Farsai Taemaitree, Yoshitaka Koseki, Hitoshi Kasai
- Organizer
  Tohoku University's Chemistry Summer School 2019
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication of antimicrobial nanoparticles2019
- Author(s)
  山内啓大朗, 谷田恵太, 小関良卓, 笠井均
- Organizer
  令和元年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication of antimicrobial nanoparticles2019
- Author(s)
  山内啓大朗, 谷田恵太, 小関良卓, 笠井均
- Organizer
  2019年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Tannic acid-modified SN-38 nano-prodrugs toward effective anticancer drug delivery2019
- Author(s)
  Nozomi Saito, Farsai Taemaitree, Yoshitaka Koseki, Ryuju Suzuki, Anh Thi Ngoc Dao, Hitoshi Kasai
- Organizer
  Sendai Albi Knowledge in Engineering Seminars
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Fabrication of hinokitiol-modified podophyllotoxin nano-prodrugs and controlling their drug release2019
- Author(s)
  谷田恵太, 小関良卓, 清水和恵, 梅澤洋史, 笠井均
- Organizer
  2019年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Facile synthesis of cyclopentenone from glucose derivative2019
- Author(s)
  渡辺俊碩, 小関良卓, 神島尭明, 笠井均
- Organizer
  2019年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Fabrication of cholesterol-modified drug nanoparticles2019
- Author(s)
  小関良卓, 笠井均
- Organizer
  令和元年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] リンカーの長さが異なるポドフィロトキシン-ヒノキチオール誘導体の合成とそのナノ・プロドラッグの作製2019
- Author(s)
  谷田恵太, 小関良卓, 清水和恵, 梅澤洋史, 笠井均
- Organizer
  第41回日本バイオマテリアル学会大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Fabrication of cholesterol-modified drug nanoparticles2019
- Author(s)
  小関良卓, 笠井均
- Organizer
  2019年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Facile synthesis of cyclopentenone from glucose derivative2019
- Author(s)
  渡辺俊碩,小関良卓,神島尭明,笠井均
- Organizer
  令和元年度化学系学協会東北大会
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Effect of the Structure on the Drug Release from Brinzolamide based Nano Eye-Drops2019
- Author(s)
  Yoshitaka Koseki, Yoshikazu Ikuta, Kota Sato, Shigenobu Aoyagi, Satoshi Inada, Tsunenobu Onodera, Hidetoshi Oikawa, Koji Nishiguchi, Toru Nakazawa, Hitoshi Kasai
- Organizer
  2019 KJF International Conference on Organic Materials for Electronics and Photonics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Surface Modification of SN-38 Nano-Prodrugs for Enhancing the Efficiency of Anticancer Drug Delivery2019
- Author(s)
  Farsai Taemaitree, Yoshitaka Koseki, Ryuju Suzuki, Anh T. N. Dao, Hitoshi Kasai
- Organizer
  Okinawa Colloids 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Synthesis of cyclopentenone from biomass resources2019
- Author(s)
  Toshihiro Watanabe, Yoshitaka Koseki, Takaai Kamishima, Hitoshi Kasai
- Organizer
  Tohoku University's Chemistry Summer School 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H02785
[Presentation] Surface Modification of SN-38 Nano-Prodrugs for Enhancing the Efficiency of Anticancer Drug Delivery2019
- Author(s)
  F. Taemaitree, Y. Koseki, R. Suzuki, A. T. N. Dao, H. Kasai
- Organizer
  Okinawa Colloids 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690
[Presentation] Self-Assemble Tannic Acid and Iron Complexes on Nano-Prodrugs Surface Prevents Aggregation and Enhances Anticancer Drug Delivery Efficiency2019
- Author(s)
  F. Taemaitree, Y. Koseki, N. Saito, R. Suzuki, R. Suzuki, A. T. N. Dao, H. Kasai
- Organizer
  2019 KJF International Conference on Organic Materials for Electronics and Photonics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15690

1. Kasai Hitoshi (30312680)

# of Collaborated Projects: 3 results

# of Collaborated Products: 62 results
2. Tsuda Satoru (60791093)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 猪瀬朋子 (10772296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 田中啓文 (90373191)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 中澤徹 (30361075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 佐藤孝太 (50732327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 國分太貴 (30646443)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 雲林院宏 (40519352)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 根本知己 (50291084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 石岡千加史 (60241577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KWON Eunsang

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. SUZUKI Masato

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. TAEMAITREE FARSAI

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Koseki Yoshitaka 小関 良卓

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多重刺激応答型ナノ・プロドラッグの開発Principal Investigator

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タンデム型プロドラッグ活性化によるがん細胞内選択的な薬物治療法の開発Principal Investigator

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がん細胞特有の刺激に応答し薬物を放出する新規抗がん薬ナノ粒子の開発

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Development of scarring quantification technology and nanoparticles for inhibition of bleb scarring with high tissue penetration

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Intracellular synthesis of anti-cancer agent by ligand delivery cheimstryPrincipal Investigator

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Site-specific chemical adsorption on graphene nanoribbon toward active band-gap engineering

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Development of anti-cancer nanodrugs with high drug loading capacity and dispersion stability by surface modification

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[Journal Article] Fabrication of anti-inflammatory nano eye-drops composed of dexamethasone prodrugs2023

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[Journal Article] Label-Free Tracking of Nanoprodrug Cellular Uptake and Metabolism Using Raman and Autofluorescence Imaging2023

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[Journal Article] Design of guaiazulene derivatives-conjugated podophyllotoxin nano-prodrug toward anticancer drug delivery2022

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[Journal Article] Polymeric functionalization of podophyllotoxin carrier-free drug nanoparticles for enhancing bioavailability and in?vitro cellular imaging2022

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[Journal Article] Conversion of 2,5-Bis(hydroxymethyl)furan to Highly Oxidized Cyclopentenones under Catalyst-free Conditions in Water2022

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[Journal Article] Development of camptothecin nano-prodrugs based on trimethyl lock groups toward selective drug release in cancer cells2022

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[Journal Article] Fabrication of size-controlled SN-38 pure drug nanocrystals through an ultrasound-assisted reprecipitation method toward efficient drug delivery for cancer treatment2021

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Koseki Yoshitaka 小関良卓