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Kubo Toshiyuki  久保 俊之

ORCIDConnect your ORCID iD *help
Researcher Number 80784313
Other IDs
Affiliation (Current) 2023: 札幌医科大学, 医学部, 訪問研究員
Affiliation (based on the past Project Information) *help 2021: 札幌医科大学, 医学部, 訪問研究員
2018 – 2020: 札幌医科大学, 医学部, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 53010:Gastroenterology-related
Keywords
Principal Investigator
大腸がん / スクリーニング / メチル化 / 分子マーカー / 大腸腫瘍 / 前癌病変 / 微小環境 / がん線維芽細胞 / 浸潤 / 大腸癌 / 癌関連線維芽細胞
  • Research Projects

    (2 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (11 People)
  •  大腸癌浸潤における癌関連線維芽細胞の機能解明と診断・治療への応用Principal Investigator

    • Principal Investigator
      久保 俊之
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Sapporo Medical University
  •  Risk prediction and early detection of colorectal cancer by aberrant DNA methylation in bowel lavage fluidPrincipal Investigator

    • Principal Investigator
      Kubo Toshiyuki
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Sapporo Medical University

All 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Insulin-Like Growth Factor 2 and Incidence of Liver Cancer in a Nested Case?Control Study2021

    • Author(s)
      Adachi Yasushi、Nojima Masanori、Mori Mitsuru、Himori Ryogo、Kubo Toshiyuki、Akutsu Noriyuki、Lin Yingsong、Kurozawa Youichi、Wakai Kenji、Tamakoshi Akiko
    • Journal Title

      Cancer Epidemiology, Biomarkers & Prevention

      Volume: 30 Pages: 2130-2135

    • DOI

      10.1158/1055-9965.epi-21-0481

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08312, KAKENHI-PROJECT-20K08335
  • [Journal Article] Esophageal large cell neuroendocrine carcinoma2021

    • Author(s)
      Kubo Toshiyuki、Adachi Yasushi、Ishii Yoshifumi、Endo Takao
    • Journal Title

      Digestive and Liver Disease

      Volume: 53 Pages: 502-503

    • DOI

      10.1016/j.dld.2020.05.026

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08335
  • [Journal Article] Activated macrophages promote invasion by early colorectal cancer via an interleukin 1β‐serum amyloid A1 axis2021

    • Author(s)
      Sudo Gota、Aoki Hironori、Yamamoto Eiichiro、Takasawa Akira、Niinuma Takeshi、Yoshido Ayano、Kitajima Hiroshi、Yorozu Akira、Kubo Toshiyuki、Harada Taku、Ishiguro Kazuya、Kai Masahiro、Katanuma Akio、Yamano Hiro‐o、Osanai Makoto、Nakase Hiroshi、Suzuki Hiromu
    • Journal Title

      Cancer Science

      Volume: 112 Pages: 4151-4165

    • DOI

      10.1111/cas.15080

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08398, KAKENHI-PROJECT-20K17057, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-20K07409, KAKENHI-PROJECT-20K07662, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-21K07985, KAKENHI-PROJECT-21K16846
  • [Journal Article] Mediterranean fever gene-associated enterocolitis in an elderly Japanese woman2021

    • Author(s)
      Shibata Yasuhiro、Ishigami Keisuke、Kazama Tomoe、Kubo Toshiyuki、Yamano Hiro-o、Sugita Shintaro、Murata Masaki、Nakase Hiroshi
    • Journal Title

      Clinical Journal of Gastroenterology

      Volume: 14 Pages: 1661-1666

    • DOI

      10.1007/s12328-021-01497-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K08335
  • [Journal Article] Upregulation of AEBP1 in endothelial cells promotes tumor angiogenesis in colorectal cancer.2020

    • Author(s)
      Yorozu Akira、Yamamoto Eiichiro、Niinuma Takeshi、Tsuyada Akihiro、Maruyama Reo、Kitajima Hiroshi、Numata Yuto、Kai Masahiro、Sudo Gota、Kubo Toshiyuki、Nishidate Toshihiko、Okita Kenji、Takemasa Ichiro、Nakase Hiroshi、Sugai Tamotsu、Takano Kenichi、Suzuki Hiromu
    • Journal Title

      Cancer Sci.

      Volume: - Pages: 1631-1644

    • DOI

      10.1111/cas.14360

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K07949, KAKENHI-PROJECT-17K08700, KAKENHI-PROJECT-18K15325, KAKENHI-PROJECT-20K07412, KAKENHI-PROJECT-20K08335, KAKENHI-PROJECT-19H03518, KAKENHI-PROJECT-18K15220, KAKENHI-PROJECT-19K18736
  • [Journal Article] Insulin-like Growth Factor-1, Insulin-like Growth Factor Binding Protein-3 and the Incidence of Malignant Neoplasms in a Nested Case?Control Study2020

    • Author(s)
      Adachi Yasushi、Nojima Masanori、Mori Mitsuru、Himori Ryogo、Kubo Toshiyuki、Yamano Hiro-o.、Lin Yingsong、Wakai Kenji、Tamakoshi Akiko
    • Journal Title

      Cancer Prevention Research

      Volume: -

    • DOI

      10.1158/1940-6207.capr-19-0375

    • NAID

      120007018430

    • Data Source
      KAKENHI-PROJECT-18K15325
  • [Journal Article] Circulating insulin‐like growth factor binding protein‐3 and risk of gastrointestinal malignant tumors2019

    • Author(s)
      Adachi Yasushi、Nojima Masanori、Mori Mitsuru、Kubo Toshiyuki、Yamano Hiro‐o、Lin Yingsong、Wakai Kenji、Tamakoshi Akiko、for JACC Study
    • Journal Title

      Journal of Gastroenterology and Hepatology

      Volume: 34 Pages: 2104-2111

    • DOI

      10.1111/jgh.14753

    • Data Source
      KAKENHI-PROJECT-18K15325
  • [Journal Article] Gastric Xanthomas and Fundic Gland Polyps as Endoscopic Risk Indicators of Gastric Cancer2019

    • Author(s)
      Yamashita Kentaro、Suzuki Ryo、Kubo Toshiyuki、Onodera Kei、Iida Tomoya、Saito Mayuko、Arimura Yoshiaki、Endo Takao、Nojima Masanori、Nakase Hiroshi
    • Journal Title

      Gut and Liver

      Volume: 13 Pages: 409-414

    • DOI

      10.5009/gnl17136

    • Data Source
      KAKENHI-PROJECT-18K15325
  • [Journal Article] Percutaneous endoscopic gastrojejunostomy for treating superior mesenteric artery syndrome2019

    • Author(s)
      Kubo Toshiyuki、Adachi Yasushi、Kikuchi Takefumi、Mita Hiroaki、Endo Takao
    • Journal Title

      Gastrointestinal Endoscopy

      Volume: 90 Pages: 983-984

    • DOI

      10.1016/j.gie.2019.07.001

    • Data Source
      KAKENHI-PROJECT-18K15325
  • [Journal Article] 拡大内視鏡診断と分子生物学的解析が可能であったTSA の癌化症例2018

    • Author(s)
      久保俊之、山野泰穂、山本英一郎、三橋慧、鈴木拓、長谷川匡、永塚真、菅井有、仲瀬裕志
    • Journal Title

      INTESTINE

      Volume: 22 Pages: 485-492

    • Data Source
      KAKENHI-PROJECT-18K15325
  • [Presentation] Helicobacter pylori除菌後胃がんと背景胃粘膜におけるDNAメチローム解析.2021

    • Author(s)
      山本英一郎,吉戸文乃,須藤豪太,三橋慧,北嶋洋志,新沼猛,甲斐正広,原田拓,佐々木基,久保俊之,山野泰穂,仲瀬裕志,菅井有,鈴木拓.
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08335
  • [Presentation] 活性化マクロファージはIL-1β-SAA1 axisを介して早期大腸がんの浸潤を促進する.2021

    • Author(s)
      須藤豪太,山本英一郎,青木敬則,髙澤啓,新沼猛,久保俊之,萬顕,吉戸文乃,北嶋洋志,甲斐正広,小山内誠,仲瀬裕志,鈴木拓.
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08335
  • [Presentation] 新規頭頸部癌関連long non-coding RNAの同定と機能解析.2021

    • Author(s)
      新沼猛,北嶋洋志,畠中柚衣,関口翔平,萬顕,久保俊之,佐々木基,原田拓,甲斐正広,仲瀬裕志,鈴木拓.
    • Organizer
      第80回日本癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-20K08335
  • 1.  山本 英一郎 (60567915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 2.  SUZUKI Hiromu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 3.  NAKASE Hiroshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 4.  TAKASAWA Akira
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 5.  阿久津 典之
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  青木 敬則
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  須藤 豪太
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  原田 拓
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  萬 顕
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 10.  菅井 有
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  北嶋 洋志
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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