Nakakido Makoto 中木戸誠

Researcher Number	80784511
Other IDs
Affiliation (Current)	2023: 東京大学, 大学院工学系研究科(工学部), 講師
Affiliation (based on the past Project Information) *help	2020 – 2022: 東京大学, 大学院工学系研究科(工学部), 講師 2017 – 2019: 東京大学, 大学院工学系研究科(工学部), 助教 2016: 東京大学, 大学院工学系研究科(工学部), 特任研究員
Review Section/Research Field	Principal Investigator Biomolecular chemistry Except Principal Investigator Transformative Research Areas, Section (II) / Complex systems / Basic Section 27040:Biofunction and bioprocess engineering-related / Basic Section 49050:Bacteriology-related / Medium-sized Section 48:Biomedical structure and function and related fields
Keywords	Principal Investigator 分子認識 / 多重特異性 / メチル基転移酵素 / 相互作用 / 物理化学 / 蛋白質 / 酵素 / 翻訳後修飾 Except Principal Investigator 病原性微生物 / 金属取り込み … More / 低分子化抗体 / 低分子化合物 / 物理化学 / 蛋白質エンジニアリング / ダイナミクス / 抗体 / A群レンサ球菌 / 金属輸送体 / 抗体治療薬 / 連携研究の推進 / 研究成果の社会発信 / 学術領域の体系化 / 異分野交流 / 国内外動向調査 / 国内外の動向調査 / 脳 / 脳分子回収 / 血液中に帰還 / 高分子集合体 / 細胞学 / 蛍光偏光 / 顕微分光法 Less

A群レンサ球菌の金属輸送系を標的とした治療薬剤としての人工抗体の取得
- Principal Investigator
  
  相川知宏
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kyoto University
Innovative nanotechnology for probing molecular landscapes in the brain
- Principal Investigator
  
  安楽泰孝
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokyo
脳分子を回収して帰還する「はやぶさ型ナノマシン」の開発
- Principal Investigator
  
  安楽泰孝
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  The University of Tokyo
Elucidation and Control of Local Fractions in Protein Engineering
- Principal Investigator
  
  津本浩平
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 27040:Biofunction and bioprocess engineering-related
- Research Institution
  The University of Tokyo
生命金属動態の理解と制御のための分子認識素子の開発
- Principal Investigator
  
  津本浩平
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  The University of Tokyo
生命現象に迫るユニバーサルな蛍光偏光顕微観測法開発
- Principal Investigator
  
  寺田純雄
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 48:Biomedical structure and function and related fields
- Research Institution
  Tokyo Medical and Dental University
Elucidation of the molecular mechanism of multi-specific substrate recognition by the methyltransferasePrincipal Investigator
- Principal Investigator
  
  Nakakido Makoto
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biomolecular chemistry
- Research Institution
  The University of Tokyo

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Book

[Book] 生命金属ダイナミクス～生体内における金属の挙動と制御～2021
- Author(s)
  中木戸誠, 津本浩平
- Total Pages
  564
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437060
- Data Source
  KAKENHI-PROJECT-20H02531
[Book] 機器分析ハンドブック 2 高分子・分離分析編2020
- Author(s)
  中木戸誠, 長門石曉, 津本浩平
- Total Pages
  192
- Publisher
  化学同人
- ISBN
  9784759820225
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Structure and role of the linker domain of the iron surface-determinant protein IsdH in heme transportation in Staphylococcus aureus.2022
- Author(s)
  Valenciano-Bellido Sandra、Caaveiro Jose M.M.、Morante Koldo、Sushko Tatyana、Nakakido Makoto、Nagatoishi Satoru、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: - Pages: 101995-101995
- DOI
  10.1016/j.jbc.2022.101995
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Journal Article] Antibody recognition of complement Factor H reveals a flexible loop involved in Atypical Hemolytic Uremic Syndrome pathogenesis2022
- Author(s)
  Yokoo Takanori、Tanabe Aki、Yoshida Yoko、Caaveiro Jose M.M.、Nakakido Makoto、Ikeda Yoichiro、Fujimura Yoshihiro、Matsumoto Masanori、Entzminger Kevin、Maruyama Toshiaki、Okumura C.J.、Nangaku Masaomi、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: - Pages: 101962-101962
- DOI
  10.1016/j.jbc.2022.101962
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-21K08272
[Journal Article] Proteomic identification and validation of novel interactions of the putative tumor suppressor PRELP with membrane proteins including IGFI-R and p75NTR2021
- Author(s)
  Kosuge Hirofumi、Nakakido Makoto、Nagatoishi Satoru、Fukuda Tetsuya、Bando Yasuhiko、Ohnuma Shin-ichi、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100278-100278
- DOI
  10.1016/j.jbc.2021.100278
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-18H02082, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Structural basis for antigen recognition by methylated lysine?specific antibodies2021
- Author(s)
  Ishii M, Nakakido M, Caaveiro JMM, Kuroda D, Okumura CJ, Maruyama T, Entzminger K, Tsumoto K.
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 296 Pages: 100176-100176
- DOI
  10.1074/jbc.ra120.015996
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03522, KAKENHI-PROJECT-20H02531, KAKENHI-PLANNED-19H05766
[Journal Article] Delicate balance among thermal stability, binding affinity, and conformational space explored by single-domain VHH antibodies2021
- Author(s)
  Ikeuchi Emina、Kuroda Daisuke、Nakakido Makoto、Murakami Akikazu、Tsumoto Kouhei
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Pages: 20624-20624
- DOI
  10.1038/s41598-021-98977-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PROJECT-19H03522
[Journal Article] Mechanism of dimerization and structural features of human LI-cadherin2021
- Author(s)
  Yui Anna、Caaveiro Jose M.M.、Kuroda Daisuke、Nakakido Makoto、Nagatoishi Satoru、Goda Shuichiro、Maruno Takahiro、Uchiyama Susumu、Tsumoto Kouhei
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 297 Pages: 101054-101054
- DOI
  10.1016/j.jbc.2021.101054
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-19H05766, KAKENHI-PLANNED-18H05425, KAKENHI-PROJECT-19H03522
[Journal Article] Characterization of a putative maltodextrin-binding protein of Streptococcus pyogenes, SPs0871 and the development of a VHH inhibitor2021
- Author(s)
  Yamawaki T, Nakakido M, Ujiie K, Aikawa C, Nakagawa I, Tsumoto K
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 6 Pages: 1-7
- DOI
  10.1016/j.bbrc.2021.05.056
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07537, KAKENHI-PROJECT-18KK0193, KAKENHI-PLANNED-19H05766, KAKENHI-PUBLICLY-20H05504, KAKENHI-PROJECT-19H03471, KAKENHI-PROJECT-21K19376
[Journal Article] Structure-based design and discovery of novel anti-tissue factor antibodies with cooperative double-point mutations, using interaction analysis2020
- Author(s)
  Chiba Shuntaro、Tanabe Aki、Nakakido Makoto、Okuno Yasushi、Tsumoto Kouhei、Ohta Masateru
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Pages: 17590-17590
- DOI
  10.1038/s41598-020-74545-4
- Data Source
  KAKENHI-PROJECT-20H02531
[Journal Article] Dual-sensitive nanomicelles enhancing systemic delivery of therapeutically active antibodies specifically into the brain2020
- Author(s)
  Jinbing Xie, Daniel Gonzalez-Carter, Theofilus A. Tockary, Noriko Nakamura, Yonger Xue, Makoto Nakakido, Hiroki Akiba, Anjaneyulu Dirisala, Xueying Liu, Kazuko Toh, Tao Yang, Zengtao Wang, Shigeto Fukushima, Junjie Li, Sabina Quader, Kouhei Tsumoto, Takanori Yokota, Yasutaka Anraku*, and Kazunori Kataoka
- Journal Title
  
  ACS nano
  
  Volume: - Pages: 6729-6742
- DOI
  10.1021/acsnano.9b09991
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14100, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-18K18393
[Journal Article] Production and characterization of a novel site-specific-modifiable anti-OX40-receptor single-chain variable fragment for targeted drug delivery2018
- Author(s)
  Tanabe A, Nakano K, Nakakido M, Nagatoishi S, Tanaka Y, Tsumoto K, Uchimaru K, Watanabe T.
- Journal Title
  
  Biophys. Biochem. Res. Commun.
  
  Volume: 496 Pages: 614-620
- DOI
  10.1016/j.bbrc.2018.01.051
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H06693
[Journal Article] Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody.2018
- Author(s)
  Miyanabe K, Akiba H, Kuroda D, Nakakido M, Kusano-Arai O, Iwanari H, Hamakubo T, Caaveiro J, and Tsumoto K
- Journal Title
  
  J Biochem.
  
  Volume: in press
- NAID
  40021625331
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06693
[Journal Article] Regulation of poly(ADP-Ribose) polymerase 1 functions by post-translational modifications2018
- Author(s)
  Piao L, Fujioka K, Nakakido M, Hamamoto R.
- Journal Title
  
  Front Biosci (Landmark Ed)
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06693
[Journal Article] Molecular basis for governing the morphology of type I collagen fibrils by Osteomodulin2018
- Author(s)
  Tashima T, Nagatoishi S, Caaveiro J, Nakakido M, Sagara H, Kusano-Arai O, Iwanari H, Mimuro H, Hamakubo T, Ohnuma S, Tsumoto K
- Journal Title
  
  Commun. Biol.
  
  Volume: in press
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H06693
[Journal Article] Biophysical characterization of the interaction between heme and proteins responsible for heme transfer in Streptococcus pyogenes2017
- Author(s)
  Hoshino M, Nakakido M, Nagatoishi S, Aikawa C, Nakagawa I, Tsumoto K.
- Journal Title
  
  Biophys. Biochem. Res. Commun.
  
  Volume: 493 Pages: 1109-1114
- DOI
  10.1016/j.bbrc.2017.09.055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08775, KAKENHI-PROJECT-17K19552, KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H05188, KAKENHI-PROJECT-16H06693
[Journal Article] Thermodynamic analyses of amino acid residues at the interface of an antibody B2212A and its antigen roundabout homolog 12017
- Author(s)
  A. Yui, H. Akiba, S. Kudo, M. Nakakido, S. Nagatoishi, K. Tsumoto
- Journal Title
  
  J. Biochem.
  
  Volume: 162 Pages: 255-258
- DOI
  10.1093/jb/mvx050
- NAID
  40021380511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H02420, KAKENHI-PROJECT-16H04710, KAKENHI-PROJECT-16H06693, KAKENHI-PROJECT-25000006
[Journal Article] Regulation of Poly(ADP-Ribose) Polymerase 1 Functions by Post-Translational Modifications2017
- Author(s)
  Piao L, Fujioka K, Nakakido M, Hamamoto R.
- Journal Title
  
  Frontiers in bioscience
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] 化膿連鎖球菌由来金属トランスポーターに対する機能阻害剤探索2021
- Author(s)
  中木戸誠、竹内美結、伊藤翔、相川知宏、長門石曉、中川一路、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 化膿連鎖球菌由来金属獲得蛋白質MtsAに対する機能阻害剤の探索2021
- Author(s)
  中木戸誠、竹内美結、長門石曉、相川知宏、中川一路、津本浩平
- Organizer
  第94回　日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 膜蛋白質の膜外領域を認識する抗体の取得2021
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Acquisition of novel VHH antibodies to synaptic organizers for application to molecular imaging2021
- Author(s)
  横尾尚典、中木戸誠、柚﨑通介、津本浩平
- Organizer
  第44回日本神経科学大会　CJK 第１回国際会議
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] aHUSに関連する補体抑制因子CFHと診断薬取得に向けた特異的抗体の機能解析2021
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、カアベイロホセ、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 化膿連鎖球菌由来金属獲得蛋白質MtsAに対する機能阻害剤の探索2021
- Author(s)
  中木戸誠、竹内美結、長門石曉、相川知宏、中川一路、津本浩平
- Organizer
  第94回　日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Physicochemical studies of mutations in framework regions of VHH focusing on intramolecular interactions with CDR32021
- Author(s)
  木下清晶、中木戸誠,、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第59回日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 化膿レンサ球菌のマルトース/マルトデキストリン結合蛋白質SPs0871の特性評価及びその機能を阻害するVHH抗体の探索2021
- Author(s)
  山脇つくし、中木戸誠、相川知宏、中川一路、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHHにおけるCDR3-Framework region間分子内相互作用に着目したフレームワーク改変の物理化学的解析2021
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第21回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 膜蛋白質Glut1の細胞外領域を認識する抗体取得法の提案2021
- Author(s)
  住川　太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第94回　日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] The Molecular Basis of How SNP in LI-cadherin Affected Cancer Metastasis2020
- Author(s)
  由井杏奈、菊池智佳、郷田秀一郎、工藤翔太、秋葉宏樹、中木戸誠、黒田大祐、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Structural analysis of a peptide fragment grafted onto the Adhiron scaffold2020
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] VHH抗体β-hairpin型CDR3を利用したペプチド設計手法の探索2020
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  第43回　日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 化膿連鎖球菌の金属獲得蛋白質MtsAに対する機能阻害剤の探索2020
- Author(s)
  竹内美結、中木戸誠、長門石曉、河出来時、相川知宏、中川一路、津本浩平
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] aHUSに関連する補体抑制因子CFHと特異的抗体の機能解析2020
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第93回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 分子動力学シミュレーションを用いたCDR-Graftingによる合成VHHにおける分子挙動の解析2020
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第58回　日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] aHUSに関連する補体抑制因子CFHと特異的抗体の機能解析2020
- Author(s)
  横尾尚典、田部亜季、中木戸誠、長門石曉、吉田瑶子、池田洋一郎、南学正臣、津本浩平
- Organizer
  第93回　日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Obtaining antibodies against Staphyloccus aureus2020
- Author(s)
  Valenciano　S, Sandra Bellido, Jose M.M. Caaveiro, Nakakido M, Nagatoishi S, Tsumoto K
- Organizer
  2020年度　医科学研究所G2発表会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 分子動力学シミュレーションを用いたCDR-Graftingによる合成VHHにおける分子挙動の解析2020
- Author(s)
  木下清晶、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第58回　日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Molecular Basis for Heme Extraction of the Antimicrobial Target IsdH from Staphylococcus aureus from Human Hemoglobin2020
- Author(s)
  S. Valenciano, V. T. Nhuan, M. Nakakido, J. M.M. Caaveiro, K. Tsumoto
- Organizer
  Biophysical Society 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 物理化学的アプローチによる低分子阻害剤の探索および抗体阻害剤の開発2020
- Author(s)
  中木戸誠、相川知宏、長門石曉、妹尾暁暢、竹内美結、星野将人、下村拓矢、カアベイロホセ、中川一路、津本浩平
- Organizer
  第93回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 化膿連鎖球菌の金属獲得蛋白質MtsAに対する機能阻害剤の探索2020
- Author(s)
  竹内美結、中木戸誠、長門石曉、河出来時、相川知宏、中川一路、津本浩平
- Organizer
  第93回　日本生化学会大会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Application of β-hairpin structure of VHH CDR3 for peptide designs2020
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  2020年度　医科学研究所G2発表会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Molecular basis of increased risk of colorectal cancer metastasis caused by SNPs in LI-cadherin2020
- Author(s)
  由井杏奈、菊池智佳、郷田秀一郎、丸野孝浩、内山進、中木戸誠、黒田大祐、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第58回　日本生物物理学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] Proteomic Identification And Validation Of New Interactions Of Novel Tumor Suppressor PRELP With Membrane Proteins2020
- Author(s)
  Kosuge H, Nakakido M, Nagatoishi S, Fukuda T, Bando Y, Ohnuma S, Tsumoto K
- Organizer
  第20回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-20H02531
[Presentation] 分子動力学シミュレーションを用いたCDR-Graftingによる合成単ドメイン抗体の構造的変化の解析2019
- Author(s)
  木下清晶、森千夏、中木戸誠、黒田大祐、カアベイロホセ、津本浩平
- Organizer
  第57回　日本生物物理学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Thermodynamic, kinetic and computational analyses of the recognition mechanism of an antibody to a flexible protein antigen2019
- Author(s)
  金田生穂、長門石曉、黒田大祐、中木戸誠、カアベイロホセ、津本　浩平
- Organizer
  CBI学会2019年大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Molecular dissection of antigen recognition by methylated lysine specific antibodies2019
- Author(s)
  Nakakido M, Ishii M, Kuroda D,Jose M.M. Caaveiro, Okumura S, Maruyama T, Kevin Entzminger,Tsumoto K
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 病原性微生物における鉄獲得関連蛋白質の特性評価および抗体阻害剤の探索2019
- Author(s)
  中木戸誠、竹内美結、津本浩平
- Organizer
  第19回日本蛋白質科学会年会／第71回日本細胞生物学会大会合同年次大会
- Invited
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 熱力学・速度論に基づく抗Shh抗体の抗原結合様式解析2019
- Author(s)
  金田生穂、長門石曉、中木戸誠、黒田大祐、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 新規抗がん治療を指向したPRELP-TGFβ1相互作用の物理化学的解析2019
- Author(s)
  小菅啓史、中木戸誠、長門石曉、大沼信一、津本浩平
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 足場蛋白質Adhironに移植したαへリックスの構造解析2019
- Author(s)
  住川太一、中木戸誠、黒田大祐、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] がん転移に関するLI-cadherin一塩基多型の分子メカニズム2019
- Author(s)
  由井杏奈、菊池智佳、郷田秀一郎、工藤翔太、秋葉宏樹、中木戸誠、黒田大祐、長門石曉、新井修、岩成宏子、浜窪隆雄、津本浩平
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 化膿レンサ球菌の鉄獲得蛋白質MtsAの特性評価及び抗体阻害剤の探索2019
- Author(s)
  竹内美結、中木戸誠、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] ヒト化VHH人工合成ライブラリー構築を目指した合成ヒト化VHHの物性機能解析2019
- Author(s)
  木下清晶、森千夏、中木戸誠、黒田大祐、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] DESIGN AND BIOPHYSICAL EVALUATION OF Β-HAIRPIN PEPTIDES DERIVED FROM SINGLE-DOMAIN VHH ANTIBODIES2019
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  第56回ペプチド討論会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 物理化学測定と分子シミュレーションを用いた抗体親和性成熟過程の解析2019
- Author(s)
  樋渡隼人、黒田大祐、中木戸誠、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] Characterization of ligand-specificity of red pigment concentrating hormone receptpr of the kuruma prawn Marsupenaeus japonicus2019
- Author(s)
  田部亜季、中木戸誠、山本菜央佳、中野和民、内丸薫、津本浩平
- Organizer
  第19回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] VHH抗体CDR3を利用したβ-hairpin型ペプチド設計法の検討2019
- Author(s)
  山本晃一、中木戸誠、黒田大祐、長門石曉、森本淳平、山東信介、津本浩平
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-19H05766
[Presentation] 分子シミュレーションと物理化学解析による抗体の熱安定性に関する研究2018
- Author(s)
  河上恵理、黒田大祐、中木戸誠、津本浩平
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] Structural, physicochemical and computational analysis to reveal the mechanism of recognition of phosphorylated antigen by an antibody2018
- Author(s)
  Kawade R, Akiba H, Nakakido M, Kuroda D, Maruyama T, Okumura S, Kevin E, Caaveiro J, Tsumoto K
- Organizer
  日本化学会第98春季年会
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] Analysis of the denaturation midpoint to design the VHH with high thermal stability2018
- Author(s)
  Emina Ikeuchi,Daisuke Kuroda, Makoto Nakakido, Maiko Yoshida, Narutoshi Tsukahara, Akikazu Murakami, Kouhei Tsumoto
- Organizer
  62nd Annual Meeting of the Biophysical Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] "Weak electrostatic interaction of an extracellular matrix protein plays a key role in a shapecontrol2017
- Author(s)
  田島卓実、長門石暁、カアベイロホセ、中木戸誠、相良洋、三室仁美、大沼信一、津本浩平
- Organizer
  第17回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] 抗ペプチド抗体による硫酸化CCR5ペプチド認識機構の熱力学的解析2017
- Author(s)
  宮鍋一紘、秋葉　宏樹、中木戸　誠、カアベイロ　ホセ、高松　佑一郎、山下　雄史、津本　浩平
- Organizer
  第17回　日本蛋白質科学会年会
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] B2212A一本鎖抗体と抗原ROBO1の界面に存在するアミノ酸残基の役割の解明に向けた熱力学的解析2017
- Author(s)
  由井杏奈、工藤翔太、秋葉宏樹、中木戸誠、長門石曉、井上豪、浜窪隆雄、津本浩平
- Organizer
  第11回　バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] アミノ酸電荷交換に関する抗原-抗体相互作用の物理化学解析2017
- Author(s)
  吉田浩平、木吉真人、中木戸誠、長門石暁、曽我真司、白井宏樹、津本浩平
- Organizer
  第11回　バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] Physicochemical analysis of antigen-antibody interaction associated with charge exchange of amino acids2017
- Author(s)
  Kouhei Yoshida, Masato Kiyoshi, Daisuke Kuroda, Makoto Nakakido, Satoru Nagatoishi, Shinji Soga, Hiroki Shirai, Kouhei Tsumoto
- Organizer
  The Second International Symposium on Biofunctional Chemistry (ISBC 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] インターロイキン11シグナルを制御するシングルドメイン抗体の探索2017
- Author(s)
  森　千夏、中木戸誠、長門石曉、津本浩平
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] 基質選択的な阻害を目指したメチル基転移酵素SMYD2の多重特異的基質認識機構の解明2017
- Author(s)
  青木将洋、中木戸誠、津本浩平
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] ファージディスプレイによるメチル化リジン特異的抗体の取得2017
- Author(s)
  石井美咲、中木戸誠、津本浩平
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16H06693
[Presentation] PRMT6 increases cytoplasmic localization of p21CDKN1A in cancer cells through arginine methylation and makes more resistant to cytotoxic agents2016
- Author(s)
  Makoto Nakakido, Yusuke Nakamura, Ryuji Hamamoto
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川県、横浜市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16H06693

1. 津本浩平 (90271866)

# of Collaborated Projects: 2 results

# of Collaborated Products: 53 results
2. 安楽泰孝 (60581585)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 長門石曉 (30550248)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
4. 黒田大祐 (60756732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
5. 相川知宏 (70725499)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 野澤孝志 (10598858)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 川井隆之 (60738962)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 竹本さやか (70372365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 寺田純雄 (00262022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 川岸将彦 (60323606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 齊藤健太 (60374659)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 佐藤啓介 (60644044)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 中川一路

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 吉田瑶子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. ディリサラアンジャネユル

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakakido Makoto 中木戸 誠

Research Projects

Research Products

Co-Researchers

A群レンサ球菌の金属輸送系を標的とした治療薬剤としての人工抗体の取得

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Innovative nanotechnology for probing molecular landscapes in the brain

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脳分子を回収して帰還する「はやぶさ型ナノマシン」の開発

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Elucidation and Control of Local Fractions in Protein Engineering

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生命金属動態の理解と制御のための分子認識素子の開発

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生命現象に迫るユニバーサルな蛍光偏光顕微観測法開発

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Elucidation of the molecular mechanism of multi-specific substrate recognition by the methyltransferasePrincipal Investigator

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[Book] 生命金属ダイナミクス～生体内における金属の挙動と制御～2021

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[Book] 機器分析ハンドブック 2 高分子・分離分析編2020

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[Journal Article] Structure and role of the linker domain of the iron surface-determinant protein IsdH in heme transportation in Staphylococcus aureus.2022

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[Journal Article] Antibody recognition of complement Factor H reveals a flexible loop involved in Atypical Hemolytic Uremic Syndrome pathogenesis2022

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[Journal Article] Proteomic identification and validation of novel interactions of the putative tumor suppressor PRELP with membrane proteins including IGFI-R and p75NTR2021

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[Journal Article] Structural basis for antigen recognition by methylated lysine?specific antibodies2021

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[Journal Article] Delicate balance among thermal stability, binding affinity, and conformational space explored by single-domain VHH antibodies2021

Author(s)

Nakakido Makoto 中木戸誠