Nagata Yuka 長田夕佳

Researcher Number	80802016
Other IDs	https://orcid.org/0000-0002-1530-6411
Affiliation (Current)	2025: 金沢大学, 薬学系, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 金沢大学, 薬学系, 助教 2018: 富山大学, 和漢医薬学総合研究所, 研究員
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 52010:General internal medicine-related Except Principal Investigator General internal medicine(including psychosomatic medicine)
Keywords	Principal Investigator マスト細胞 / アレルゲン / IgE受容体 / IgE / 脱感作 / M1/M2マクロファージ / アレルギー / 外来抗原情報 / マクロファージ / 単球 … More Except Principal Investigator … More 東洋医学 / 腸管粘膜免疫 / 制御性T細胞 / 経口免疫療法 / 葛根湯 / 食物アレルギー Less

低親和性アレルゲンを用いた安全・有効な次世代型脱感作療法の研究Principal Investigator
- Principal Investigator
  
  長田夕佳
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kanazawa University
The role of mast cell and monocyte/mecrophage interaction in the regulation of allergic responsesPrincipal Investigator
- Principal Investigator
  
  Nagata Yuka
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kanazawa University
漢方薬を利活用した制御性T細胞誘導による食物抗原耐性の獲得と経口免疫療法への応用Principal Investigator
- Principal Investigator
  
  長田夕佳
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  University of Toyama
Establishment of highly effective therapy for food allergy by concomitant use of kakkonto with oral immunotherapy
- Principal Investigator
  
  Yamamoto Takeshi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  University of Toyama

All 2024 2023 2022 2021 2020 2018 2017 2016

All Journal Article Presentation

[Journal Article] Ephedrine Alkaloid-Independent High-Affinity Immunoglobulin-E Receptor (FcεRI) Internalization Results in CCL2 Production without Inducing Mast Cell Degranulat2023
- Author(s)
  Yuka Nagata, Yohei Sasaki, Ryo Suzuki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 46 Pages: 1-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K15992
[Journal Article] Copper in airborne fine particulate matter (PM2.5) from urban sites causes the upregulation of pro-inflammatory cytokine IL-8 in human lung epithelial A549 cells.2023
- Author(s)
  Amma C, Inomata Y, Kohno R, Satake M, Furukawa A, Nagata Y, Sugiyama H, Seto T, Suzuki R.
- Journal Title
  
  Environ. Geochem. Health.
  
  Volume: 45 Issue: 8 Pages: 5879-589
- DOI
  10.1007/s10653-023-01599-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14345, KAKENHI-PROJECT-23K06129, KAKENHI-PROJECT-22K19373, KAKENHI-PROJECT-23K24028
[Journal Article] VAMP7 knockdown in secretory granules impairs CCL2 secretion in mast cells.2023
- Author(s)
  Sakamoto M, Nagata Y, Furukawa A, Kusada T, Inamoto S, Senda T, Hirashima N, Suzuki R.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 8 Pages: 149258-149258
- DOI
  10.1016/j.bbrc.2023.149258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14345, KAKENHI-PROJECT-23K06129, KAKENHI-PROJECT-22K19373, KAKENHI-PROJECT-23K24028
[Journal Article] Multifunctional regulation of VAMP3 in exocytic and endocytic pathways of RBL-2H3 cells2022
- Author(s)
  Mishima Satomi、Sakamoto Marin、Kioka Hikaru、Nagata Yuka、Suzuki Ryo
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13 Pages: 885868-885868
- DOI
  10.3389/fimmu.2022.885868
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19373, KAKENHI-PROJECT-20K15992, KAKENHI-PROJECT-23K24028
[Journal Article] FcεRI: a master regulator of mast cell functions2022
- Author(s)
  Nagata Y, Suzuki R
- Journal Title
  
  Cells
  
  Volume: 11 Issue: 4 Pages: 622-622
- DOI
  10.3390/cells11040622
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03369, KAKENHI-PROJECT-20K15992, KAKENHI-PROJECT-22K19373, KAKENHI-PROJECT-23K24028
[Journal Article] Leukotriene D4 accelerates antigen-mediated mast cell responses via the cysteinyl leukotriene 1 receptor2022
- Author(s)
  Fujisawa Sakura、Nagata Yuka、Suzuki Ryo
- Journal Title
  
  Cellular Immunology
  
  Volume: 382 Pages: 104632-104632
- DOI
  10.1016/j.cellimm.2022.104632
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19373, KAKENHI-PROJECT-20K15992, KAKENHI-PROJECT-23K24028
[Journal Article] Ephedra Herb, Mao, Inhibits Antigen-Induced Mast Cell Degranulation by Induction of the Affinity Receptor for IgE Internalization2021
- Author(s)
  Nagata Yuka、Ando Hirokazu、Sasaki Yohei、Suzuki Ryo
- Journal Title
  
  Pharmaceutical Research
  
  Volume: 38 Issue: 4 Pages: 569-581
- DOI
  10.1007/s11095-021-03020-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K15992, KAKENHI-PROJECT-19H03369, KAKENHI-PROJECT-18K19396
[Journal Article] FcεRI Cluster Size Determines Effective Mast Cell Desensitization without Effector Responses in vitro2021
- Author(s)
  Nagata Y, Suzuki R
- Journal Title
  
  Int Arch Allergy Immunol
  
  Volume: 30 Issue: 4 Pages: 1-9
- DOI
  10.1159/000520132
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03369, KAKENHI-PROJECT-20K15992
[Journal Article] Improvement of Therapeutic Efficacy of Oral Immunotherapy in Combination with Regulatory T Cell-Inducer Kakkonto in a Murine Food Allergy Model.2017
- Author(s)
  Nagata Y, Yamamoto T, Hayashi M, Hayashi S, Kadowaki M.
- Journal Title
  
  PLoS One.
  
  Volume: 12 Issue: 1 Pages: e0170577-e0170577
- DOI
  10.1371/journal.pone.0170577
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K09234, KAKENHI-PROJECT-15K18873, KAKENHI-PROJECT-16H05276
[Presentation] アレルギー応答の加齢変化及びその調節機構の解析2024
- Author(s)
  日置七菜子、天谷美月、長田夕佳、古川敦、鈴木亮
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] マスト細胞-好中球の相互作用及び好中球蛋白質Ly6Gを介したアレルギー応答調節機構2024
- Author(s)
  五十嵐杏実, 長田夕佳, 古川敦, 鈴木亮
- Organizer
  第47回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] ケミカルライブラリースクリーニングによるアレルギー反応調節分子の探索と機能解析2024
- Author(s)
  守田汐里、古川敦、長田夕佳、鈴木亮
- Organizer
  日本薬学会北陸支部第136 回例会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] Antigen-IgE affinity is an important factor influencing FcεRI desensitization without mast cell activation2024
- Author(s)
  Yuka Nagata, Miyu Kimura, Atsushi Furukawa, Ryo Suzuki
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] 加齢によるアレルギー炎症の変化と機能解析2024
- Author(s)
  天谷美月、日置七菜子、長田夕佳、古川敦、鈴木亮
- Organizer
  日本薬学会北陸支部第136 回例会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] カーボンブラック粒子による肺胞マクロファージでの毒性発現機構の解析2024
- Author(s)
  石原萌宏、古川敦、長田夕佳、鈴木亮
- Organizer
  第 31 回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] マスト細胞における分泌顆粒の不均質性とVAMP7によるCCL2分泌制御機構の解析2023
- Author(s)
  坂本真凜、長田夕佳、古川敦、草田智之、稲本奨平、千田知美、平嶋尚英、鈴木亮
- Organizer
  日本薬学会北陸支部第135 回例会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] Antigen-IgE affinity is an important factor influencing FcεRI desensitization without mast cell activation2023
- Author(s)
  Yuka Nagata, Miyu Kimura, Atsushi Furukawa, Ryo Suzuki
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] 好中球蛋白質Ly6Gによるマスト細胞の活性化調節機構2023
- Author(s)
  五十嵐杏実、長田夕佳、古川敦、鈴木亮
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] 大気環境中微粒子カーボンブラックによる肺胞マクロファージでの毒性誘導機構2023
- Author(s)
  石原萌宏，古川敦，長田夕佳，鈴木亮
- Organizer
  フォーラム2023衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] ケミカルライブラリースクリーニングによるマスト細胞活性制御分子の探索2023
- Author(s)
  守田汐里、古川敦、長田夕佳、鈴木亮
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] ハプテン価数の異なるアレルゲンが調節するマスト細胞応答の解析2023
- Author(s)
  倉坪眞千, 長田夕佳, 古川敦, 鈴木亮
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] Cytotoxic mechanism induced by carbon black nanoparticles2023
- Author(s)
  古川敦、安間千智、長田夕佳、瀬戸章文、鈴木亮
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] Allergen-IgE affinity shapes mast cell FcεRI responses and impacts the safety of desensitization2023
- Author(s)
  Yuka Nagata
- Organizer
  第72回日本アレルギー学会学術集会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] マスト細胞のケモカイン分泌におけるVAMP7の機能解析2023
- Author(s)
  坂本真凜, 長田夕佳, 古川敦, 草田智之, 稲本奨平, 千田知美, 平嶋尚英, 鈴木亮
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] Mast cell-monocyte interaction initiates allergic inflammation by regulating macrophage differentiation2023
- Author(s)
  長田夕佳、村上栞、栗田紗希、田村真美、古川敦、鈴木亮
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] マスト細胞の分泌顆粒の不均質性と分泌メカニズムの解析2023
- Author(s)
  坂本真凜、長田夕佳、古川敦、草田智之、稲本奨平、千田知美、平嶋尚英、鈴木亮
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] Benzo[a]pyrene induces NLRP1 expression and promotes prolonged inflammasome signaling in lung epithelial cells2023
- Author(s)
  Yuka Nagata, Risa Kohno, Tomohiro Ishihara, Chisato Amma, Yayoi Inomata, Takafumi Seto and Ryo Suzuki
- Organizer
  第30回日本免疫毒性学会学術年会
- Data Source
  KAKENHI-PROJECT-23K14345
[Presentation] ロイコトリエン受容体を介したアレルギー応答におけるフィードバック調節機構2022
- Author(s)
  長田夕佳, 藤沢咲良, 鈴木亮
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] 好中球由来タンパク質 Ly6G によるアレルギー応答制御機構の解析2022
- Author(s)
  五十嵐杏実、長田夕佳、古川敦、鈴木亮
- Organizer
  日本薬学会北陸支部第134回例会
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] 大気環境中微粒子による肺胞マクロファージへの毒性発現機構の解析2022
- Author(s)
  石原萌宏、古川敦、長田夕佳、鈴木亮
- Organizer
  日本薬学会北陸支部第134回例会
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] Leukotriene D4 accelerates antigen-mediated mast cell responses via the cysteinyl leukotriene 1 receptor2022
- Author(s)
  Nagata Y, Fujisawa S, Suzuki R
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] 親和性の異なる混合アレルゲンを用いた IgE 受容体活性化調節機構の解析2022
- Author(s)
  倉坪眞千、中矢姫菜子、古川敦、長田夕佳、鈴木亮
- Organizer
  日本薬学会北陸支部第134回例会
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] カーボンブラックナノ粒子による肺胞上皮細胞での毒性発現機構の解析2022
- Author(s)
  安間千智、長田夕佳、古川敦、瀬戸章文、鈴木亮
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] Immunoglobulin E receptor cluster size determines effective mast cell desensitization without effector responses in vitro2021
- Author(s)
  Yuka Nagata, Ryo Suzuki
- Organizer
  米国細胞生物学会議 Cell Bio Virtual 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] 麻黄によるIgE受容体internalizationを介したマスト細胞の脱顆粒抑制機構2021
- Author(s)
  長田夕佳、安藤広和、佐々木陽平、鈴木亮
- Organizer
  日本薬学会第141年会（広島）
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] 加熱・非加熱抗原を用いたマスト細胞in vitro脱感作機構の解析2021
- Author(s)
  長田夕佳、鈴木亮
- Organizer
  フォーラム2021 衛生薬学・環境トキシコロジー
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] Clarification of FcεRI-IgE Cluster Formation in Desensitized Mast Cells2021
- Author(s)
  Yuka Nagata, Ryo Suzuki
- Organizer
  第8回アジア・オセアニア免疫学会議 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] Clarification of FcεRI-IgE cluster size in OVA desensitized mast cells2021
- Author(s)
  Yuka Nagata, Ryo Suzuki
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] Ephedra herb, Mao, inhibits allergen-induced mast cell degranulation by inducing IgE-FcεRIinternalization2020
- Author(s)
  Nagata Yuka、Ando Hirokazu、Sasaki Yohei、Suzuki Ryo
- Organizer
  JSA/WAO Joint Congress 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] Ephedra Herb, Mao, Inhibits Antigen-Induced Mast Cell Degranulation by the Induction of the Affinity Receptor for IgE Internalization2020
- Author(s)
  Nagata Yuka、Ando Hirokazu、Sasaki Yohei、Suzuki Ryo
- Organizer
  American Academy of Allergy, Asthma & Immunology (AAAAI) Virtual Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K15992
[Presentation] Long-Term Effect of Combined Therapy of Oral Immunotherapy and Japanese Traditional Medicine Kakkonto on Food Allergy Mice.2018
- Author(s)
  Nagata Y., Yamamoto T., Kadowaki M.
- Organizer
  American Academy of Allergy Asthma & Immunology (AAAAI) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 葛根湯併用経口免疫療法による食物アレルギー治療の寛解維持効果についてモデルマウスを用いた検討2018
- Author(s)
  山本武, 長田夕佳, 門脇真
- Organizer
  第35回和漢医薬学会学術大会, 2018, 9, 1-2, 岐阜.
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 経口免疫療法モデルマウスを用いた葛根湯併用療法の寛解維持効果の検討2018
- Author(s)
  長田夕佳, 山本武, 門脇真
- Organizer
  第67回日本アレルギー学会学術大会, 2018, 6, 22-24, 千葉.
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] Intestinal Regulatory T Cells Induced by Kakkonto, a Traditional Japanese Herbal Medicine, Improve Therapeutic Efficacy of Oral Immunotherapy in Food Allergy Model Mice.2017
- Author(s)
  Yamamoto T., Nagata Y., Hayashi M., Kadowaki M.
- Organizer
  18th International Congress of Mucosal Immunology (ICMI 2017)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 経口免疫療法と葛根湯の併用療法による食物アレルギーの治療効果増加の機序の検討.2017
- Author(s)
  山本武, 長田夕佳, 林美智慧, 苟巧, 門脇真
- Organizer
  第34回和漢医薬学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 食物アレルギー病態モデルに対する葛根湯と経口免疫療法の併用療法によるレチノイン酸代謝酵素抑制を介した制御性T細胞の誘導.2017
- Author(s)
  長田夕佳, 山本武, 門脇真
- Organizer
  第66回日本アレルギー学会学術大会
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 葛根湯と経口免疫療法の併用療法モデルによるレチノイン酸代謝酵素抑制を介した制御性T細胞の誘導.2016
- Author(s)
  長田夕佳, 山本武, 門脇真.
- Organizer
  第65回日本アレルギー学会学術大会
- Place of Presentation
  東京
- Year and Date
  2016-06-17
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 腸管制御性T細胞誘導能を持つ葛根湯と経口免疫療法の併用療法は食物アレルギー病態モデルでの治療効果を亢進させる.2016
- Author(s)
  長田夕佳, 山本武, 林美智慧, 門脇真.
- Organizer
  日本薬学会北陸支部第128回例会
- Place of Presentation
  金沢
- Data Source
  KAKENHI-PROJECT-16K09234
[Presentation] 経口免疫療法による食物アレルギーの治療における葛根湯の併用効果のモデルマウスを用いた検討.2016
- Author(s)
  山本武, 長田夕佳, 林美智慧, 門脇真.
- Organizer
  第33回和漢医薬学会学術大会
- Place of Presentation
  東京
- Year and Date
  2016-08-27
- Data Source
  KAKENHI-PROJECT-16K09234

1. Yamamoto Takeshi (70316181)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
2. Ito Yasunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 鈴木亮

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results

Nagata Yuka 長田 夕佳

Research Projects

Research Products

Co-Researchers

低親和性アレルゲンを用いた安全・有効な次世代型脱感作療法の研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of mast cell and monocyte/mecrophage interaction in the regulation of allergic responsesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

漢方薬を利活用した制御性T細胞誘導による食物抗原耐性の獲得と経口免疫療法への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of highly effective therapy for food allergy by concomitant use of kakkonto with oral immunotherapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Ephedrine Alkaloid-Independent High-Affinity Immunoglobulin-E Receptor (FcεRI) Internalization Results in CCL2 Production without Inducing Mast Cell Degranulat2023

Author(s)

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[Journal Article] Copper in airborne fine particulate matter (PM2.5) from urban sites causes the upregulation of pro-inflammatory cytokine IL-8 in human lung epithelial A549 cells.2023

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[Journal Article] VAMP7 knockdown in secretory granules impairs CCL2 secretion in mast cells.2023

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[Journal Article] Multifunctional regulation of VAMP3 in exocytic and endocytic pathways of RBL-2H3 cells2022

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[Journal Article] FcεRI: a master regulator of mast cell functions2022

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[Journal Article] Leukotriene D4 accelerates antigen-mediated mast cell responses via the cysteinyl leukotriene 1 receptor2022

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[Journal Article] Ephedra Herb, Mao, Inhibits Antigen-Induced Mast Cell Degranulation by Induction of the Affinity Receptor for IgE Internalization2021

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[Journal Article] FcεRI Cluster Size Determines Effective Mast Cell Desensitization without Effector Responses in vitro2021

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[Journal Article] Improvement of Therapeutic Efficacy of Oral Immunotherapy in Combination with Regulatory T Cell-Inducer Kakkonto in a Murine Food Allergy Model.2017

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[Presentation] アレルギー応答の加齢変化及びその調節機構の解析2024

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[Presentation] マスト細胞-好中球の相互作用及び好中球蛋白質Ly6Gを介したアレルギー応答調節機構2024

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Nagata Yuka 長田夕佳