ICHIMARU Yoshimi 市丸嘉

… Alternative Names

市丸嘉イチマルヨシミ

Less

Researcher Number	80802917
Other IDs
Affiliation (Current)	2026: 湘南医療大学, 薬学部医療薬学科, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 湘南医療大学, 薬学部医療薬学科, 講師 2019: 金城学院大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related Except Principal Investigator Experimental pathology
Keywords	Principal Investigator 膵臓癌 / キナーゼ阻害剤 / 抗がん剤 / 金属錯体 / がん / 錯体 / インディルビン / 亜鉛 Except Principal Investigator 自然発症モデルマウス / 膵管癌 … More / アポトーシス / 転移 / 細胞増殖 / チロシンキナーゼ阻害剤 / トランスレーショナルリサーチ / 遺伝子改変マウスモデル / MMP / AKT / SPAK/JNK / Kras/ERK / CDK1/Cyclin B1 / リン酸化阻害剤 / インディルビン / 遺伝子改変マウス / シグナル経路 / 浸潤 / 細胞周期 / インディルビン誘導体 / 創薬開発 / KPCマウス / 膵癌モデルマウス / 膵癌 Less

Creation and experimental treatment of indirubin-zinc complexes for the development of novel pancreatic cancer therapeuticsPrincipal Investigator
- Principal Investigator
  
  市丸嘉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  湘南医療大学
Development of anti-cancer drugs using pancreatic cancer mouse model
- Principal Investigator
  
  SANO Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Nihon University

All 2025 2024 2023 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Design, Synthesis, and Characterization of 1-(Anthracen-9-ylmethyl)-1,5,9-triazacyclododecane (Ant-[12]aneN3) and Its DNA Photocleavage Activity2025
- Author(s)
  Ichimaru Yoshimi、Kato Koichi、Yamaguchi Yoshihiro、Sakamoto Takayuki、Jin Wanchun、Kurihara Masaaki、Fujita Mikako、Otsuka Masami、Kurosaki Hiromasa
- Journal Title
  
  Chemical and Pharmaceutical Bulletin
  
  Volume: 73 Issue: 2 Pages: 103-107
- DOI
  10.1248/cpb.c24-00705
- ISSN
  0009-2363, 1347-5223
- Year and Date
  2025-02-15
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15244, KAKENHI-PROJECT-23K14339
[Journal Article] Synthesis and Anticancer Activity of Bis(2-picolyl)amine Derivatives with a Biaryl Moiety as a Photosensitizer2025
- Author(s)
  Ichimaru Yoshimi、Kato Koichi、Sogawa Koushirou、Egawa Daichi、Kato Hideaki、Katakawa Kazuaki、Jin Wanchun、Kurihara Masaaki、Kurosaki Hiromasa
- Journal Title
  
  Chemistry
  
  Volume: 7 Issue: 2 Pages: 41-41
- DOI
  10.3390/chemistry7020041
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06950, KAKENHI-PROJECT-24K13420, KAKENHI-PROJECT-23K14339
[Journal Article] (5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-1-ido-κN 1)(1,4,8,11-tetraazacyclotetradecane-κ4 N)zinc(II) perchlorate2024
- Author(s)
 Ichimaru Yoshimi、Kato Koichi、Jin Wanchun、Kurihara Masaaki、Kurosaki Hiromasa
- Journal Title
 
 IUCrData
 
 Volume: 9 Issue: 5
- DOI
 10.1107/s2414314624004310
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-21K15244, KAKENHI-PROJECT-23K14339
[Journal Article] [1-(Anthracen-9-ylmethyl)-1,4,7,10-tetraazacyclododecane]chloridozinc(II) nitrate2024
- Author(s)
  Ichimaru Yoshimi、Sugiura Kirara、Kato Koichi、Kondo Yuki、Kurihara Masaaki、Jin Wanchun、Imai Masanori、Kurosaki Hiromasa
- Journal Title
  
  IUCrData
  
  Volume: 9 Issue: 7
- DOI
  10.1107/s2414314624006655
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15244, KAKENHI-PROJECT-23K14339
[Journal Article] Indirubin 3'-Oxime Inhibits Migration, Invasion, and Metastasis InVivo in Mice Bearing Spontaneously Occurring Pancreatic Cancer via Blocking the RAF/ERK, AKT, and SAPK/JNK Pathways2019
- Author(s)
  Ichimaru Y, Sano M, Kajiwara I, Tobe T, Yoshioka H, Hayashi K, Ijichi H, Miyairi S
- Journal Title
  
  Translational Oncology
  
  Volume: 12 Issue: 12 Pages: 1574-1582
- DOI
  10.1016/j.tranon.2019.08.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08772
[Journal Article] 5-Bromoindirubin 3'-(O-oxiran-2-ylmethyl)oxime: A long-acting anticancer agent and a suicide inhibitor for epoxide hydrolase.2017
- Author(s)
  Ichimaru Y, Fujii T, Saito H, Sano M, Uchiyama T, Miyairi S
- Journal Title
  
  Bioorg Med Chem
  
  Volume: 25 Issue: 17 Pages: 4665-4676
- DOI
  10.1016/j.bmc.2017.07.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08772
[Journal Article] Induction of cell death in pancreatic ductal adenocarcinoma by indirubin 3'-oxime and 5-methoxyindirubin 3'-oxime in vitro and in vivo.2017
- Author(s)
  Sano M, Ichimaru Y, Kurita M, Hayashi E, Homma T, Saito H, Masuda S, Nemoto N, Hemmi A, Suzuki T, Miyairi S, Hao H
- Journal Title
  
  Cancer Letters
  
  Volume: 397 Pages: 72-82
- DOI
  10.1016/j.canlet.2017.03.031
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08772, KAKENHI-PROJECT-26460496, KAKENHI-PROJECT-15K08357
[Presentation] 光増感部としてビアリールを導入した亜鉛錯体のDNA光切断活性2025
- Author(s)
  市丸嘉，加藤紘一，黒崎博雅，栗原正明
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K14339
[Presentation] アントラセンを導入した[12]aneN3 誘導体－亜鉛錯体のDNA切断活性2024
- Author(s)
  市丸嘉，加藤紘一，黒崎博雅，栗原正明
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K14339
[Presentation] ビアリールを導入したBis(2-picolyl)amine誘導体－亜鉛錯体のDNA光切断活性2024
- Author(s)
  市丸嘉，加藤紘一，黒崎博雅，栗原正明
- Organizer
  第68回日本薬学会関東支部会
- Data Source
  KAKENHI-PROJECT-23K14339
[Presentation] アントラセンを導入したBis(2-picolyl)amine 誘導体－亜鉛錯体のDNA光切断活性2023
- Author(s)
  市丸嘉，加藤紘一，栗原正明，黒崎博雅
- Organizer
  第67回日本薬学会関東支部会
- Data Source
  KAKENHI-PROJECT-23K14339
[Presentation] 新規インディルビン誘導体の構造活性相関：抗がん活性と水溶性2020
- Author(s)
  小島瑠実子、近藤綾香、中村仁衣菜、林一彦、宮入伸一、市丸嘉
- Organizer
  日本薬学会　第140年会
- Data Source
  KAKENHI-PROJECT-17K08772
[Presentation] メトキシ置換インディルビン誘導体の抗がん活性再評価2020
- Author(s)
  中村仁衣菜、小島瑠実子、近藤綾香、林一彦、宮入伸一、市丸嘉
- Organizer
  日本薬学会　第140年会
- Data Source
  KAKENHI-PROJECT-17K08772
[Presentation] インディルビンの可溶化：Epox/Indへの応用2018
- Author(s)
  市丸嘉，吉岡弘毅，加藤紘一，佐野誠，林一彦，宮入伸一
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-17K08772
[Presentation] 浸潤性膵管癌の自然発症モデルマウスに対するインディルビン誘導体の治療効果の検証2018
- Author(s)
  市丸嘉，佐野誠，吉岡弘毅，林一彦，宮入伸一
- Organizer
  第64回日本薬学学会東海支部総会
- Data Source
  KAKENHI-PROJECT-17K08772
[Presentation] 膵癌移植モデルにおけるインディルビン誘導体の抗腫瘍効果2017
- Author(s)
  佐野誠，市丸嘉，林恵美子，齋藤弘明，本間琢，廣谷ゆかり，根本則道，増田しのぶ，逸見明博，宮入伸一，羽尾裕之
- Organizer
  第106回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K08772

1. SANO Makoto (70339323)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 宮入伸一 (50209855)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
3. KATAKAWA Kazuaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ICHIMARU Yoshimi 市丸 嘉

市丸 嘉 イチマル ヨシミ

Research Projects

Research Products

Co-Researchers

Creation and experimental treatment of indirubin-zinc complexes for the development of novel pancreatic cancer therapeuticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of anti-cancer drugs using pancreatic cancer mouse model

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Design, Synthesis, and Characterization of 1-(Anthracen-9-ylmethyl)-1,5,9-triazacyclododecane (Ant-[12]aneN3) and Its DNA Photocleavage Activity2025

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Synthesis and Anticancer Activity of Bis(2-picolyl)amine Derivatives with a Biaryl Moiety as a Photosensitizer2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] (5-Fluoro-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-1-ido-κ<i>N</i> <sup>1</sup>)(1,4,8,11-tetraazacyclotetradecane-κ<sup>4</sup> <i>N</i>)zinc(II) perchlorate2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] [1-(Anthracen-9-ylmethyl)-1,4,7,10-tetraazacyclododecane]chloridozinc(II) nitrate2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Indirubin 3'-Oxime Inhibits Migration, Invasion, and Metastasis InVivo in Mice Bearing Spontaneously Occurring Pancreatic Cancer via Blocking the RAF/ERK, AKT, and SAPK/JNK Pathways2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 5-Bromoindirubin 3'-(O-oxiran-2-ylmethyl)oxime: A long-acting anticancer agent and a suicide inhibitor for epoxide hydrolase.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induction of cell death in pancreatic ductal adenocarcinoma by indirubin 3'-oxime and 5-methoxyindirubin 3'-oxime in vitro and in vivo.2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 光増感部としてビアリールを導入 した亜鉛錯体のDNA光切断活性2025

Author(s)

Organizer

Data Source

[Presentation] アントラセンを導入した[12]aneN3 誘導体－亜鉛錯体のDNA切断活性2024

Author(s)

Organizer

Data Source

[Presentation] ビアリールを導入したBis(2-picolyl)amine誘導体－亜鉛錯体のDNA光切断活性2024

Author(s)

Organizer

Data Source

[Presentation] アントラセンを導入したBis(2-picolyl)amine 誘導体－亜鉛錯体のDNA光切断活性2023

Author(s)

Organizer

Data Source

[Presentation] 新規インディルビン誘導体の構造活性相関：抗がん活性と水溶性2020

Author(s)

Organizer

Data Source

[Presentation] メトキシ置換インディルビン誘導体の抗がん活性再評価2020

Author(s)

Organizer

Data Source

[Presentation] インディルビンの可溶化：Epox/Indへの応用2018

ICHIMARU Yoshimi 市丸嘉

市丸嘉イチマルヨシミ

[Presentation] 光増感部としてビアリールを導入した亜鉛錯体のDNA光切断活性2025