Omata Daiki 小俣大樹

Researcher Number	80803113
Other IDs
Affiliation (Current)	2022: 帝京大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2020 – 2022: 帝京大学, 薬学部, 講師 2017 – 2019: 帝京大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 90130:Medical systems-related / Medical systems Except Principal Investigator Medical systems / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 90130:Medical systems-related
Keywords	Principal Investigator マイクロバブル / 超音波 / 脳 / ドラッグデリバリー / デリバリー / 脳腫瘍 / がん / 免疫療法 / 血液脳関門 / 腫瘍 / ドラッグデリバリーシステム / 薬物送達 / 中枢神経系疾患 … More Except Principal Investigator … More マイクロバブル / 超音波 / DDS / セラノスティクス / 血液脳関門 / 腫瘍新生血管 / 超音波造影 / 超音波診断と治療 / 低侵襲治療システム / 超音波セラノスティクス / EPR効果 / ナノ液滴 / ペルフルオロヘキサン / 超音波治療 / 癌治療 / 血液脳関門開口 / 脳腫瘍 / アルツハイマー病 / BBBオープニング Less

神経変性疾患治療に向けたマイクロバブルと超音波による核酸搭載ナノ粒子送達法の開発Principal Investigator
- Principal Investigator
  
  小俣大樹
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Teikyo University
リピッドバブルとMRIガイド経頭蓋超音波による血液脳関門開口と脳内薬物送達
- Principal Investigator
  
  丸山一雄
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Teikyo University
Development of brain tumor-targeted drug delivery system using microbubbles and ultrasoundPrincipal Investigator
- Principal Investigator
  
  Omata Daiki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90130:Medical systems-related
- Research Institution
  Teikyo University
Development of acoustic droplet formulation and construction of innovative drug delivery method for low EPR cancer
- Principal Investigator
  
  Maruyama Kazuo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  Teikyo University
Development of microbubbles for ultrasound-triggered drug delivery to brainPrincipal Investigator
- Principal Investigator
  
  Omata Daiki
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Medical systems
- Research Institution
  Teikyo University
Development of bubble preparation for ultrasound theranostics
- Principal Investigator
  
  Maruyama Kazuo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Medical systems
- Research Institution
  Teikyo University

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Ultrasound and microbubble-mediated drug delivery and immunotherapy2022
- Author(s)
  Omata Daiki、Munakata Lisa、Maruyama Kazuo、Suzuki Ryo
- Journal Title
  
  Journal of Medical Ultrasonics
  
  Volume: -
- DOI
  10.1007/s10396-022-01201-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K20717
[Journal Article] 血液脳関門と超音波　薬物動態視点から2022
- Author(s)
  鈴木亮、小俣大樹
- Journal Title
  
  Clinical Neuroscience
  
  Volume: 40 Pages: 222-227
- Data Source
  KAKENHI-PROJECT-19K20717
[Journal Article] Enhanced Vascular Permeability by Microbubbles and Ultrasound in Drug Delivery2021
- Author(s)
  Omata Daiki、Munakata Lisa、Maruyama Kazuo、Suzuki Ryo
- Journal Title
  
  Biol. Pharm. Bull.
  
  Volume: 44 Issue: 10 Pages: 1391-1398
- DOI
  10.1248/bpb.b21-00453
- NAID
  130008095753
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K20717, KAKENHI-PROJECT-20H04519
[Journal Article] Ultrasound image-guided gene delivery using three-dimensional diagnostic ultrasound and lipid- based microbubbles2021
- Author(s)
  Omata Daiki、Munakata Lisa、Kageyama Saori、Suzuki Yuno、Maruyama Tamotsu、Shima Tadamitsu、Chikaarashi Takumi、Kajita Naoya、Masuda Kohji、Tsuchiya Naoto、Maruyama Kazuo、Suzuki Ryo
- Journal Title
  
  Journal of Drug Targeting
  
  Volume: 30 Pages: 200-207
- DOI
  10.1080/1061186x.2021.1953510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K20717, KAKENHI-PROJECT-20H04547, KAKENHI-PROJECT-20H04519
[Journal Article] A Pilot Study on Efficacy of Lipid Bubbles for Theranostics in Dogs with Tumors2020
- Author(s)
  Yokoe Inoru、Murahata Yusuke、Harada Kazuki、Sunden Yuji、Omata Daiki、Unga Johan、Suzuki Ryo、Maruyama Kazuo、Okamoto Yoshiharu、Osaki Tomohiro
- Journal Title
  
  Cancers
  
  Volume: 12 Pages: 2423-2423
- DOI
  10.3390/cancers12092423
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04554, KAKENHI-PROJECT-18K12060, KAKENHI-PROJECT-20H04542
[Journal Article] Effect of lipid shell composition in DSPG-based microbubbles on blood flow imaging with ultrasonography2020
- Author(s)
  Maruyama Tamotsu、Sugii Mutsumi、Omata Daiki、Unga Johan、Shima Tadamitsu、Munakata Lisa、Kageyama Saori、Hagiwara Fumiko、Suzuki Yuno、Maruyama Kazuo、Suzuki Ryo
- Journal Title
  
  Int. J. Pharm.
  
  Volume: 590 Pages: 119886-119886
- DOI
  10.1016/j.ijpharm.2020.119886
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K22505, KAKENHI-PROJECT-20H04519, KAKENHI-PROJECT-20H04554
[Journal Article] Scale-up production, characterization and toxicity of a freeze-dried lipid-stabilized microbubble formulation for ultrasound imaging and therapy2020
- Author(s)
  Unga Johan、Kageyama Saori、Suzuki Ryo、Omata Daiki、Maruyama Kazuo
- Journal Title
  
  Journal of Liposome Research
  
  Volume: 30 Pages: 297-304
- DOI
  10.1080/08982104.2019.1649282
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04554
[Journal Article] Characterization of Brain-Targeted Drug Delivery Enhanced by a Combination of Lipid-Based Microbubbles and Non-Focused Ultrasound2020
- Author(s)
  Omata Daiki、Hagiwara Fumiko、Munakata Lisa、Shima Tadamitsu、Kageyama Saori、Suzuki Yuno、Azuma Takashi、Takagi Shu、Seki Kazuhiko、Maruyama Kazuo、Suzuki Ryo
- Journal Title
  
  J. Pharm. Sci.
  
  Volume: 109 Pages: 2827-2835
- DOI
  10.1016/j.xphs.2020.06.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K20717, KAKENHI-PROJECT-19H01092, KAKENHI-PROJECT-20H04519, KAKENHI-PROJECT-20H04554, KAKENHI-PROJECT-19K21825, KAKENHI-PROJECT-20H04542
[Journal Article] Development and evaluation of stability and ultrasound response of DSPC-DPSG-based freeze-dried microbubbles.2018
- Author(s)
  Johan Unga, Daiki Omata, Nobuki Kudo, Soki Ueno, Lisa Munakata, Tadamitsu Shima, Ryo Suzuki and Kazuo Maruyama
- Journal Title
  
  J. Liposome Res.
  
  Volume: 10 Pages: 1-27
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H03196
[Presentation] 超音波とマイクロバブルを用いたシスプラチン送達による脳腫瘍治療2022
- Author(s)
  小俣大樹、萩原芙美子、宗像理紗、鈴木悠乃、丸山保、丸山一雄、鈴木亮
- Organizer
  日本薬学会　第142年会
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] マイクロバブルと超音波を利用した血管透過性促進に基づく革新的な薬物デリバリーシステム（DDS）の開発2022
- Author(s)
  鈴木亮、小俣大樹、宗像理紗、丸山一雄
- Organizer
  日本薬学会　第142年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] 超音波とマイクロバブルを用いたイメージング・治療システムの開発2021
- Author(s)
  小俣大樹
- Organizer
  第30回　日本バイオイメージング学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] 脳への薬物送達に向けた集束超音波照射条件の検討2021
- Author(s)
  垣内彩実、小俣大樹、宗像理紗、萩原芙美子、鈴木悠乃、丸山保、梅村晋一朗、吉澤晋、丸山一雄、鈴木亮
- Organizer
  第65回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-20H04554
[Presentation] 脳標的薬物デリバリーに向けたマイクロバブル開発に関する基礎的検討2021
- Author(s)
  小俣大樹、丸山保、宗像理紗、影山彩織、萩原芙美子、鈴木悠乃、丸山一雄、鈴木亮
- Organizer
  第94回　日本超音波医学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] 脳腫瘍モデルマウスに対するマイクロバブルと超音波を利用した抗がん剤治療2021
- Author(s)
  萩原芙美子、小俣大樹、宗像理紗、鈴木悠乃、丸山保、丸山一雄、鈴木亮
- Organizer
  第37回　日本DDS学会学術集会
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] 脳への薬物送達に向けた集束超音波照射条件の検討2021
- Author(s)
  垣内彩実、小俣大樹、宗像理紗、萩原芙美子、鈴木悠乃、丸山保、梅村晋一朗、吉澤晋、丸山一雄、鈴木亮
- Organizer
  第65回　日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] 集束超音波とマイクロバブルによるmRNA封入脂質ナノ粒子の脳内送達の研究2021
- Author(s)
  吉田道春、小川昂輝、加藤直也、日宇健、水上修作、小俣大樹、鈴木亮、丸山一雄、川上茂、松尾孝之
- Organizer
  第39回日本脳腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-20H04554
[Presentation] Effect of Encapsulated Gas in Lipid-based Microbubbles on Brain-targeted Drug Delivery2020
- Author(s)
  Daiki Omata, Tamotsu Maruyama, Fumiko Hagiwara, Lisa Munakata, Saori Kageyama, Yuno Suzuki, Kazuo Maruyama, Ryo Suzuki
- Organizer
  7th International Symposium on Focused Ultrasound
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] 血液脳関門オープニングに向けたマイクロバブル内包ガスの最適化2020
- Author(s)
  小俣大樹、丸山保、宗像理紗、影山彩織、萩原芙美子、鈴木悠乃、丸山一雄、鈴木亮
- Organizer
  第27回次世代医工学研究会
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] マイクロバブルを用いた効率的な血液脳関門オープニングへ向けた超音波照射条件に関する基礎的検討2020
- Author(s)
  萩原芙美子、小俣大樹、宗像理紗、影山彩織、鈴木悠乃、丸山保、島忠光、丸山一雄、鈴木亮
- Organizer
  第3回日本経頭蓋MRガイド下集束超音波治療研究会
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] リピッドバブルと220kHz経頭蓋MRIガイド集束超音波を用いた血液脳関門開通の研究2020
- Author(s)
  丸山一雄、吉田道春、加藤容崇、小俣大樹、鈴木亮、Rachmilevitch Itay、鈴木秀二、鎌田一
- Organizer
  日本超音波医学会第93回学術集会
- Data Source
  KAKENHI-PROJECT-20H04554
[Presentation] 脳標的薬物デリバリーに向けたマイクロバブル内包ガスの最適化2020
- Author(s)
  小俣大樹、丸山保、宗像理紗、影山彩織、萩原芙美子、鈴木悠乃、丸山一雄、鈴木亮
- Organizer
  第29回日本バイオイメージング学会
- Data Source
  KAKENHI-PROJECT-20H04554
[Presentation] リピッドバブルと経頭蓋集束超音波を用いたBBBオープニングによる薬物送達2020
- Author(s)
  丸山一雄、吉田道春、加藤容崇、小俣大樹、鈴木亮
- Organizer
  第36回日本DDS学会
- Data Source
  KAKENHI-PROJECT-20H04554
[Presentation] 新規マイクロバブル製剤の開発と超音波併用による薬物送達2020
- Author(s)
  丸山一雄、小俣大樹、鈴木　亮
- Organizer
  第3回日本経頭蓋MRIガイド下集束超音波治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-20H04554
[Presentation] 脳標的薬物デリバリーに向けたマイクロバブル内包ガスの最適化2020
- Author(s)
  小俣大樹、丸山保、宗像理紗、影山彩織、萩原芙美子、鈴木悠乃、丸山一雄、鈴木亮
- Organizer
  第29回日本バイオイメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] リピッドバブルとヒト用経頭蓋集束超音波装置を用いたBBBオープニングによる薬物送達に関する基礎研究2020
- Author(s)
  丸山一雄、吉田道春、加藤容崇、小俣大樹、鈴木亮
- Organizer
  日本薬剤学会第35年会
- Data Source
  KAKENHI-PROJECT-20H04554
[Presentation] Effect of Encapsulated Gas in Microbubbles on Ultrasound-based Drug Delivery for Brain2019
- Author(s)
  Daiki Omata, Tamotsu Maruyama, Fumiko Hagiwara, Lisa Munakata, Tadamitsu Shima, Saori Kageyama, Yuno Suzuki, Kazuo Maruyama, Ryo Suzuki
- Organizer
  AAPS 2019 PharmSci 360
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] Brain-targeted Drug Delivery using Ultrasound and Lipid-based Microbubbles loading Different Gases2019
- Author(s)
  Daiki Omata, Tamotsu Maruyama, Fumiko Hagiwara, Lisa Munakata, Tadamitsu Shima, Saori Kageyama, Yuno Suzuki, Kazuo Maruyama, Ryo Suzuki
- Organizer
  Liposome research days 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] 脳疾患治療に向けた血液脳関門オープニング技術の構築2019
- Author(s)
  小俣大樹、丸山一雄、鈴木亮
- Organizer
  第18回　日本超音波治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] 脳内への超音波薬物送達におけるマイクロバブル内包ガスの影響2019
- Author(s)
  丸山保、小俣大樹、宗像理紗、島忠光、萩原芙美子、鈴木悠乃、丸山一雄、鈴木亮
- Organizer
  第63回　日本薬学会　関東支部大会
- Data Source
  KAKENHI-PROJECT-19K20717
[Presentation] 超音波とマイクロバブルを用いた脳内薬物送達法の開発2019
- Author(s)
  小俣大樹、鈴木亮、Johan Unga、丸山一雄
- Organizer
  日本薬学会第129年会
- Invited
- Data Source
  KAKENHI-PROJECT-17H07119
[Presentation] 超音波診断治療システムに向けたマイクロバブルの開発2018
- Author(s)
  丸山保、小俣大樹、鈴木亮、Johan Unga、宗像理紗、影山彩織、Emma Marin、丸山一雄
- Organizer
  第17回日本超音波治療研究会
- Data Source
  KAKENHI-PROJECT-17H07119
[Presentation] リピッドバブルと超音波によるセラノスティクスと遺伝子デリバリー2018
- Author(s)
  丸山一雄,　鈴木亮,　小俣大樹,　高橋葉子,　根岸洋一
- Organizer
  日本薬学会第138年会
- Invited
- Data Source
  KAKENHI-PROJECT-16H03196
[Presentation] ENHANCEMENT OF EPR EFFECT AND DRUG DELIVERY BY THE COMBINATION OF NEW LIPID BUBBLES AND ULTRASOUND.2018
- Author(s)
  Kazuo Maruyama, Johan Unga, Daiki Omata, Tomohiro Osaki, Ryo Suzuki
- Organizer
  18th International Symposium on therapeutic ultrasound (ISTU2018).
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03196
[Presentation] 異なる気体を内包したマイクロバブルの特性評価2018
- Author(s)
  小俣大樹、丸山保、鈴木亮、Johan Unga、萩原芙美子、宗像理紗、丸山一雄
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-17H07119
[Presentation] 安定性の優れたマイクロバブルの開発に向けた基礎的検討2018
- Author(s)
  丸山保、小俣大樹、鈴木亮、ウンガヨハン、宗像理紗、ソレイマンモスタファ、丸山一雄
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-17H07119
[Presentation] Brain targeting drug delivery with lipid bubble and ultrasound2018
- Author(s)
  Omata D., Suzuki R., Unga J., Munakata L., Shima T., Kageyama S., Marin E., Maruyama K.
- Organizer
  6th International Symposium on Focused Ultrasound
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H07119
[Presentation] 安定性の優れたマイクロバブルの開発に向けた基礎的検討2018
- Author(s)
  丸山保、小俣大樹、鈴木亮、Johan Unga、宗像理紗、Mostafa Soleyman、丸山一雄
- Organizer
  日本薬剤学会第33年会
- Data Source
  KAKENHI-PROJECT-17H07119
[Presentation] Enhancement of ERP effect by the combination of lipid bubbles and ultrasound2018
- Author(s)
  Kazuo Maruyama, Johan Unga, Daiki Omata, Ryo Suzuki
- Organizer
  11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H03196
[Presentation] マイクロバブルと超音波を用いた脳標的薬物デリバリーに関する基礎的検討2018
- Author(s)
  小俣大樹、鈴木亮、萩原芙美子、Johan Unga、宗像理紗、島忠光、影山彩織、丸山一雄
- Organizer
  第27回日本バイオイメージング学会学術集会
- Data Source
  KAKENHI-PROJECT-17H07119
[Presentation] マイクロバブルの安定性に及ぼす内包ガスの影響2018
- Author(s)
  丸山保、小俣大樹、鈴木亮、Johan Unga、宗像理紗、影山彩織、Mostafa Soleyman、丸山一雄
- Organizer
  第62回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-17H07119
[Presentation] 超音波セラノスティクス用バブル製剤の開発2017
- Author(s)
  丸山一雄、Johan Unga、小俣大樹、鈴木亮
- Organizer
  第16回日本超音波治療研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16H03196
[Presentation] 脳を標的とした超音波DDSの開発に向けて2017
- Author(s)
  小俣大樹、鈴木亮、Johan Unga、丸山一雄
- Organizer
  第61回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-17H07119
[Presentation] 超音波セラノスティクスへの応用を目的とした新規血中安定型バブル製剤の創製2017
- Author(s)
  杉井むつみ、鈴木亮、小田雄介、Johan Unga、宇留賀仁史、小俣大樹、丸山一雄
- Organizer
  第32回　日本DDS学会
- Place of Presentation
  京都　The Westin Miyako Kyoto (Japan)
- Year and Date
  2017-02-21
- Data Source
  KAKENHI-PROJECT-16H03196

1. Maruyama Kazuo (30130040)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
2. 茅沼秀樹 (10329196)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 金井詠一 (20632219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 高瀬有加里 (80718057)

# of Collaborated Projects: 1 results

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5. 鈴木亮 (90384784)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
6. 小田雄介 (80505941)

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7. 吉田道春 (00795437)

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# of Collaborated Products: 4 results
8. 梅村晋一郎 (20402787)

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9. 吉澤晋 (30455802)

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10. OSAKI Tomohiro

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11. 宗像理紗

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12. 桝田晃司

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13. 関和彦

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Omata Daiki 小俣 大樹

Research Projects

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Co-Researchers

神経変性疾患治療に向けたマイクロバブルと超音波による核酸搭載ナノ粒子送達法の開発Principal Investigator

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リピッドバブルとMRIガイド経頭蓋超音波による血液脳関門開口と脳内薬物送達

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Development of brain tumor-targeted drug delivery system using microbubbles and ultrasoundPrincipal Investigator

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Development of acoustic droplet formulation and construction of innovative drug delivery method for low EPR cancer

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Development of microbubbles for ultrasound-triggered drug delivery to brainPrincipal Investigator

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Development of bubble preparation for ultrasound theranostics

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[Journal Article] Ultrasound and microbubble-mediated drug delivery and immunotherapy2022

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[Journal Article] 血液脳関門と超音波 薬物動態視点から2022

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[Journal Article] Enhanced Vascular Permeability by Microbubbles and Ultrasound in Drug Delivery2021

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[Journal Article] Ultrasound image-guided gene delivery using three-dimensional diagnostic ultrasound and lipid- based microbubbles2021

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[Journal Article] A Pilot Study on Efficacy of Lipid Bubbles for Theranostics in Dogs with Tumors2020

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[Journal Article] Effect of lipid shell composition in DSPG-based microbubbles on blood flow imaging with ultrasonography2020

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[Journal Article] Scale-up production, characterization and toxicity of a freeze-dried lipid-stabilized microbubble formulation for ultrasound imaging and therapy2020

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[Journal Article] Characterization of Brain-Targeted Drug Delivery Enhanced by a Combination of Lipid-Based Microbubbles and Non-Focused Ultrasound2020

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Omata Daiki 小俣大樹

[Journal Article] 血液脳関門と超音波　薬物動態視点から2022