KATO HIDEAKI 加藤英明

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KATO Hideaki 加藤英明

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Researcher Number	80805961
Other IDs	https://orcid.org/0000-0002-1941-5535
Affiliation (Current)	2022: 東京大学, 大学院総合文化研究科, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2022: 東京大学, 大学院総合文化研究科, 准教授
Review Section/Research Field	Principal Investigator Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 43020:Structural biochemistry-related / Transformative Research Areas, Section (III) Except Principal Investigator Biological Sciences / Medium-sized Section 47:Pharmaceutical sciences and related fields / Transformative Research Areas, Section (III) / Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields
Keywords	Principal Investigator クライオ電子顕微鏡 / 膜タンパク質 / GPCR / ニューロテンシン受容体 / Gタンパク質 / アレスチン / 創薬 / 微生物型ロドプシン / ダイナミクス / ツール開発 … More / 神経調節因子 / センサー / タンパク質工学 / ロドプシン / 光遺伝学 / 構造生物学 / 光受容体 … More Except Principal Investigator 生物物理 / 電子顕微鏡 / X線 / 蛋白質 / Ｘ線 / GPCR / DREADD / 社会性神経科学 / 死認識 / ロドプシン / 光受容 / トランスクリプトーム / 海洋微生物 / 光受容体 / 真核微生物 Less

The analysis of structural dynamics of microbial rhodopsinsPrincipal Investigator
- Principal Investigator
  
  加藤英明
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
Structural and functional analysis of novel transporter-type rhodopsinPrincipal Investigator
- Principal Investigator
  
  加藤英明
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo
Manipulation of G12/13 signaling and and drug development strategy
- Principal Investigator
  
  井上飛鳥
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Tohoku University
Neural representation of "Death" (general affairs)
- Principal Investigator
  
  奥山輝大
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
The engineering of the novel imaging tools for neuromodulatorsPrincipal Investigator
- Principal Investigator
  
  加藤英明
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  The University of Tokyo
酵素型ロドプシン：光でON-OFFする酵素が描く新しい微生物の生き様
- Principal Investigator
  
  吉澤晋
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields
- Research Institution
  The University of Tokyo
Structural analysis of NTSR1-G-protein complexesPrincipal Investigator
- Principal Investigator
  
  KATO Hideaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43020:Structural biochemistry-related
- Research Institution
  The University of Tokyo
Molecular mechanism of membrane proteins regulated by physical stimuli
- Principal Investigator
  
  Nureki Osamu
- Project Period (FY)
  2016 – 2020
- Research Category
  
  Grant-in-Aid for Specially Promoted Research
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

All 2021 2020 2019 2017 2016

All Journal Article Presentation Book

[Book] 月刊「細胞」2021年 5月号 Gタンパク質共役型受容体（GPCR）の新展開2021
- Author(s)
  松井俊貴, 小柳淳暉, 加藤英明
- Total Pages
  4
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-19H03163
[Journal Article] Crystal structure of schizorhodopsin reveals mechanism of inward proton pumping.2021
- Author(s)
  Nagiri, C., Kobayashi, K., Tomita, A., Kato, M., Kobayashi, K., Yamashita, K., Nishizawa, T., Inoue, A., Shihoya, W. and Nureki, O.
- Journal Title
  
  Molecular Cell
  
  Volume: 81 Pages: 14-14
- DOI
  10.1016/j.molcel.2021.06.024
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06294, KAKENHI-PUBLICLY-20H05437, KAKENHI-PROJECT-20J13299, KAKENHI-PROJECT-20K15728
[Journal Article] Structure of the neurotensin receptor 1 in complex with β-arrestin 12020
- Author(s)
  Huang Weijiao、Masureel Matthieu、Qu Qianhui、Janetzko John、Inoue Asuka、Kato Hideaki E.、Robertson Michael J.、Nguyen Khanh C.、Glenn Jeffrey S.、Skiniotis Georgios、Kobilka Brian K.
- Journal Title
  
  Nature
  
  Volume: 579 Pages: 303-308
- DOI
  10.1038/s41586-020-1953-1
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08264, KAKENHI-PROJECT-19H03163
[Journal Article] Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation.2020
- Author(s)
  Nakamura Ryoki、Numata Tomohiro、Kasuya Go、Yokoyama Takeshi、Nishizawa Tomohiro、Kusakizako Tsukasa、Kato Takafumi、Hagino Tatsuya、Dohmae Naoshi、Inoue Masato、Watanabe Kengo、Ichijo Hidenori、Kikkawa Masahide、Shirouzu Mikako、Jentsch Thomas J.、Ishitani Ryuichiro、Okada Yasunobu、Nureki Osamu
- Journal Title
  
  Commun. Biol.
  
  Volume: 3 Pages: 240-240
- DOI
  10.1038/s42003-020-0951-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-20K15754, KAKENHI-PLANNED-16H06574, KAKENHI-PROJECT-18H03995, KAKENHI-PROJECT-18K06864, KAKENHI-PROJECT-19K23833, KAKENHI-PROJECT-16H06294
[Journal Article] Crystal structure of plant vacuolar iron transporter VIT12019
- Author(s)
  Fukuhara S, Nakane T, Yamashita K, Ishii R, Ishitani R, Nureki O
- Journal Title
  
  Nat. Plants
  
  Volume: 74 Pages: 301-315
- DOI
  10.1038/s41477-019-0367-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-17J06203, KAKENHI-PROJECT-16H06294
[Journal Article] Conformational transitions of a neurotensin receptor 1-G(i1) complex2019
- Author(s)
  Kato Hideaki E.、Zhang Yan、Hu Hongli、Suomivuori Carl-Mikael、Kadji Francois Marie Ngako、Aoki Junken、Krishna Kumar Kaavya、Fonseca Rasmus、Hilger Daniel、Huang Weijiao、Latorraca Naomi R.、Inoue Asuka、Dror Ron O.、Kobilka Brian K.、Skiniotis Georgios
- Journal Title
  
  Nature
  
  Volume: 572 Pages: 80-85
- DOI
  10.1038/s41586-019-1337-6
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03163, KAKENHI-PROJECT-17K08264
[Journal Article] Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA62017
- Author(s)
  Taniguchi Reiya、Inoue Asuka、Sayama Misa、Uwamizu Akiharu、Yamashita Keitaro、Hirata Kunio、Yoshida Masahito、Tanaka Yoshiki、Kato Hideaki E.、Nakada-Nakura Yoshiko、Otani Yuko、Nishizawa Tomohiro、Doi Takayuki、Ohwada Tomohiko、Ishitani Ryuichiro、Aoki Junken、Nureki Osamu
- Journal Title
  
  Nature
  
  Volume: 548 Pages: 356-360
- DOI
  10.1038/nature23448
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08157, KAKENHI-PUBLICLY-16H00822, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16J07583, KAKENHI-PROJECT-16J08059, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-17H05000
[Journal Article] Structure and biological function of ENPP6, a choline-specific glycerophosphodiester-phosphodiesterase2016
- Author(s)
  Morita J, Kano K, Kato K, Takita H, Skagami H, Yamamoto Y, Mihara E, Ueda H, Sato T, Tokuyama H, Arai H, Asou H, Takagi J, Ishitani R, Nishimasu H, Nureki O, Aoki J
- Journal Title
  
  Sci. Rep.
  
  Volume: 6 Pages: 1-14
- DOI
  10.1038/srep20995
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111006, KAKENHI-PROJECT-26253001, KAKENHI-PROJECT-15J08403, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-23227004, KAKENHI-PROJECT-26860004, KAKENHI-PROJECT-16H06294
[Journal Article] Role of Asn112 in a Light-Driven Sodium Ion-Pumping Rhodopsin2016
- Author(s)
  R. Abe-Yoshizumi, K. Inoue, H. E. Kato, O. Nureki, H. Kandori*
- Journal Title
  
  Biochemistry
  
  Volume: 55 Pages: 5790-5797
- DOI
  10.1021/acs.biochem.6b00741
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104009, KAKENHI-PROJECT-15H02391, KAKENHI-PROJECT-14J40214, KAKENHI-PROJECT-26708001, KAKENHI-PROJECT-26620005, KAKENHI-PROJECT-16H06294
[Journal Article] Crystal structure of the plant receptor-like kinase TDR in complex with the TDIF peptide2016
- Author(s)
  Morita, J., Kato, K., Nakane, T., Kondo, Y., Fukuda, H., Nishimasu, H., *Ishitani, R. and *Nureki, O.
- Journal Title
  
  Nat Commun
  
  Volume: 7 Pages: 12383-12383
- DOI
  10.1038/ncomms12383
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01226, KAKENHI-PLANNED-15H05958, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-16H06294, KAKENHI-PROJECT-16H06377
[Journal Article] Crystal structures of the TRIC trimeric intracellular cation channel orthologues2016
- Author(s)
  Kasuya G, Hiraizumi M, Maturana AD, Kumazaki K, Fujiwara Y, Liu K, Nakada-Nakura Y, Iwata S, Tsukada K, Komori T, Uemura S, Goto Y, Nakane T, Takemoto M, Kato HE, Yamashita K, Wada M, Ito K, Ishitani R, Hattori M, Nureki O.
- Journal Title
  
  Cell Research
  
  Volume: 26 Pages: 1288-1301
- DOI
  10.1038/cr.2016.140
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01389, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-26291030, KAKENHI-PROJECT-16K15180, KAKENHI-PROJECT-16H06294
[Journal Article] Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization.2016
- Author(s)
  Kato K, Satouh Y, Nishimasu H, Kurabayashi A, Morita J, Fujihara Y, Oji A, Ishitani R, Ikawa M, Nureki O.
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Pages: 12198-12198
- DOI
  10.1038/ncomms12198
- NAID
  120006957420
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H05573, KAKENHI-PROJECT-15J04519, KAKENHI-PROJECT-15J08403, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-16H06276, KAKENHI-ORGANIZER-25112001, KAKENHI-PROJECT-16H06294
[Presentation] CryoEM analysis of the GPCR neurotensin receptor 1 signaling complexes2020
- Author(s)
  加藤英明
- Organizer
  東京大学　医学部リサーチカンファ
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] CryoEM analysis of the GPCR neurotensin receptor 1 signaling complexes2020
- Author(s)
  加藤英明
- Organizer
  第93回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] Structural basis for the recognition of salient signals by GPCRs2020
- Author(s)
  Hideaki Kato
- Organizer
  第43回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] CryoEM analysis of the GPCR neurotensin receptor 1-G protein complex for the future engineering of biased allosteric modulator2020
- Author(s)
  加藤英明
- Organizer
  第418回 CBI学会講演会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] CryoEM analysis of the GPCR neurotensin receptor 1-G protein complex2019
- Author(s)
  Hideaki Kato
- Organizer
  The Joint Symposium on Fusion of Biomedical and Physical/ Informational Sciences in Neurobiology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019
- Author(s)
  加藤英明
- Organizer
  名古屋工業大学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019
- Author(s)
  加藤英明
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019
- Author(s)
  加藤英明
- Organizer
  第57回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] CryoEM analysis of the GPCR neurotensin receptor 1-G protein complex for the future engineering of biased allosteric modulator2019
- Author(s)
  Hideaki Kato
- Organizer
  AHeDD2019/IPAB2019 Joint Symposium
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019
- Author(s)
  加藤英明
- Organizer
  東京大学第1292回生物科学セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163
[Presentation] Structural and conformational transition in NTSR1-Gi1 protein complex2019
- Author(s)
  加藤英明
- Organizer
  金沢大学　NanoLSIセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H03163

1. Nureki Osamu (10272460)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. 伊藤耕一 (10262073)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. MATURANA ANDRES (10452004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 石谷隆一郎 (90361568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
5. 井上飛鳥 (50525813)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 井上圭一 (90467001)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 奥山輝大 (80625955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 竹内春樹 (70548859)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 三浦恭子 (80583062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 吉澤晋 (00553108)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. UEDA Hirofumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. OTANI Yuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. NISHIZAWA Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. Yoshizumi Rei

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. Kato Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. NUMATA Tomohiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. FUJIHARA Yoshitaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 高木淳一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 徳山英利

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 新井洋由

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 志甫谷渉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 神取秀樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 近藤侑貴

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 福田裕穂

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 藤原祐一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 一條秀憲

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 糟谷豪

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 伊川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KATO HIDEAKI 加藤 英明

KATO Hideaki 加藤 英明

Research Projects

Research Products

Co-Researchers

The analysis of structural dynamics of microbial rhodopsinsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural and functional analysis of novel transporter-type rhodopsinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Manipulation of G12/13 signaling and and drug development strategy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Neural representation of "Death" (general affairs)

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The engineering of the novel imaging tools for neuromodulatorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

酵素型ロドプシン：光でON-OFFする酵素が描く新しい微生物の生き様

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural analysis of NTSR1-G-protein complexesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanism of membrane proteins regulated by physical stimuli

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 月刊「細胞」2021年 5月号 Gタンパク質共役型受容体（GPCR）の新展開2021

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Crystal structure of schizorhodopsin reveals mechanism of inward proton pumping.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure of the neurotensin receptor 1 in complex with β-arrestin 12020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cryo-EM structure of the volume-regulated anion channel LRRC8D isoform identifies features important for substrate permeation.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystal structure of plant vacuolar iron transporter VIT12019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Conformational transitions of a neurotensin receptor 1-G(i1) complex2019

Author(s)

KATO HIDEAKI 加藤英明

KATO Hideaki 加藤英明