Unregistered Unregistered 冨樫敬太

… Alternative Names

Keita Togashi 冨樫敬太

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Researcher Number	80810796
Other IDs
Affiliation (Current)	2022: 山形大学, 医学部, 医員
Affiliation (based on the past Project Information) *help	2021: 山形大学, 医学部, 病院助教 2019 – 2020: 山形大学, 医学部, 医員
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related
Keywords	Principal Investigator CEP1347 / p53 / 網膜芽細胞腫 / MDM4 / CEP-1347 / 細胞増殖抑制能 / 増殖抑制 / 細胞死 / ぶどう膜悪性黒色腫 / 眼科悪性腫瘍

Establishment of a novel treatment for uveal melanoma based on p53 pathway activationPrincipal Investigator
- Principal Investigator
  
  冨樫敬太
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Yamagata University
Clarification of mechanisms for inhibition of retinoblastoma growth by CEP-1347Principal Investigator
- Principal Investigator
  
  Keita Togashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Yamagata University

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Gemcitabine Cooperates with Everolimus to Inhibit the Growth of and Sensitize Malignant Meningioma Cells to Apoptosis Induced by Navitoclax, an Inhibitor of Anti-Apoptotic BCL-2 Family Proteins2022
- Author(s)
  Yamamoto Masahiro、Suzuki Shuhei、Togashi Keita、Sugai Asuka、Okada Masashi、Kitanaka Chifumi
- Journal Title
  
  Cancers
  
  Volume: 14 Pages: 1706-1706
- DOI
  10.3390/cancers14071706
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-21K16867
[Journal Article] Gemcitabine radiosensitization primes irradiated malignant meningioma cells for senolytic elimination by navitoclax.2021
- Author(s)
  Yamamoto Masahiro、Sanomachi Tomomi、Suzuki Shuhei、Togashi Keita、Sugai Asuka、Seino Shizuka、Sato Atsushi、Okada Masashi、Kitanaka Chifumi
- Journal Title
  
  Neurooncol Adv.
  
  Volume: 3 Pages: 1-11
- DOI
  10.1093/noajnl/vdab148
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-20K17949, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Roles for hENT1 and dCK in gemcitabine sensitivity and malignancy of meningioma.2021
- Author(s)
  Yamamoto Masahiro、Sanomachi Tomomi、Suzuki Shuhei、Uchida Hiroyuki、Yonezawa Hajime、Higa Nayuta、Takajo Tomoko、Yamada Yuki、Sugai Asuka、Togashi Keita、Seino Shizuka、Okada Masashi、Sonoda Yukihiko、Hirano Hirofumi、Yoshimoto Koji、Kitanaka Chifumi
- Journal Title
  
  Neuro Oncol.
  
  Volume: XX Pages: 1-10
- DOI
  10.1093/neuonc/noab015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17949, KAKENHI-PROJECT-18K16550, KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-20K07631
[Journal Article] Targeting Folate Metabolism Is Selectively Cytotoxic to Glioma Stem Cells and Effectively Cooperates with Differentiation Therapy to Eliminate Tumor-Initiating Cells in Glioma Xenografts2021
- Author(s)
  Okada Masashi、Suzuki Shuhei、Togashi Keita、Sugai Asuka、Yamamoto Masahiro、Kitanaka Chifumi
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22 Pages: 11633-11633
- DOI
  10.3390/ijms222111633
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-21H03040, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Inhibition of the Lipid Droplet?Peroxisome Proliferator-Activated Receptor α Axis Suppresses Cancer Stem Cell Properties2021
- Author(s)
  Kuramoto K, Yamamoto M, Suzuki S, Togashi K, Sanomachi T, Kitanaka C, Okada M.
- Journal Title
  
  Genes
  
  Volume: 12(1) Pages: 99-99
- DOI
  10.3390/genes12010099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-19K18870
[Journal Article] Dexamethasone Sensitizes Cancer Stem Cells to Gemcitabine and 5-Fluorouracil by Increasing Reactive Oxygen Species Production through NRF2 Reduction.2021
- Author(s)
  Suzuki Shuhei、Yamamoto Masahiro、Sanomachi Tomomi、Togashi Keita、Sugai Asuka、Seino Shizuka、Yoshioka Takashi、Okada Masashi、Kitanaka Chifumi
- Journal Title
  
  Life (Basel)
  
  Volume: 11 Pages: 885-885
- DOI
  10.3390/life11090885
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Lurasidone Sensitizes Cancer Cells to Osimertinib by Inducing Autophagy and Reduction of Survivin.2021
- Author(s)
  SUZUKI SHUHEI、YAMAMOTO MASAHIRO、SANOMACHI TOMOMI、TOGASHI KEITA、SEINO SHIZUKA、SUGAI ASUKA、YOSHIOKA TAKASHI、OKADA MASASHI、KITANAKA CHIFUMI
- Journal Title
  
  Anticancer Res
  
  Volume: 41 Pages: 4321-4331
- DOI
  10.21873/anticanres.15237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K18870, KAKENHI-PROJECT-19K09449, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-21K16867
[Journal Article] Metastatic Orbital Tumor From Breast Ductal Carcinoma With Neuroendocrine Differentiation Initially Presenting as Ocular Symptoms: A Case Report and Literature Review2021
- Author(s)
  Togashi Keita、Nishitsuka Koichi、Hayashi Shion、Namba Hiroyuki、Goto Sakiko、Takeda Yusuke、Suzuki Shuhei、Kato Tomoya、Yamada Yuki、Konno Eriko、Yoshioka Takashi、Yamakawa Mitsunori、Sonoda Yukihiko、Suzuki Tamio、Yamashita Hidetoshi
- Journal Title
  
  Frontiers in Endocrinology
  
  Volume: 12
- DOI
  10.3389/fendo.2021.625663
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18870
[Journal Article] Therapeutic targeting of pancreatic cancer stem cells by dexamethasone modulation of the MKP-1-JNK axis.2020
- Author(s)
  Suzuki Shuhei、Okada Masashi、Sanomachi Tomomi、Togashi Keita、Seino Shizuka、Sato Atsushi、Yamamoto Masahiro、Kitanaka Chifumi
- Journal Title
  
  J Biol Chem.
  
  Volume: 295 Pages: 18328-18342
- DOI
  10.1074/jbc.ra120.015223
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09449, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-19K18870
[Journal Article] Inhibition of Retinoblastoma Cell Growth by CEP1347 Through Activation of the P53 Pathway2020
- Author(s)
  Togashi K, Okada M, Suzuki S, Sanomachi T, Seino S, Yamamoto M, Yamashita H, Kitanaka C.
- Journal Title
  
  Anticancer Research
  
  Volume: 40(9) Pages: 4961-4968
- DOI
  10.21873/anticanres.14499
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-19K18870
[Journal Article] Verteporfin inhibits oxidative phosphorylation and induces cell death specifically in glioma stem cells.2020
- Author(s)
  Kuramoto Kenta、Yamamoto Masahiro、Suzuki Shuhei、Sanomachi Tomomi、Togashi Keita、Seino Shizuka、Kitanaka Chifumi、Okada Masashi
- Journal Title
  
  FEBS J.
  
  Volume: Epub ahead of print Pages: 2023-2036
- DOI
  10.1111/febs.15187
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02908, KAKENHI-PROJECT-20K07631, KAKENHI-PROJECT-19K18870
[Presentation] 眼球摘出に至った脈絡膜悪性黒色腫症例の腫瘍検体の初代培養による細胞株樹立の試み2020
- Author(s)
  冨樫敬太, 林思音, 岡田雅司, 大江倫太郎, 髙村浩, 今野伸弥 , 難波広幸, 赤羽梢, 西塚弘一, 山川光徳, 北中千史, 山下英俊
- Organizer
  第124回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-19K18870
[Presentation] 眼球突出を契機として原発巣が判明した神経内分泌型乳管癌の眼窩転移の1例2019
- Author(s)
  冨樫敬太, 林思音, 後藤早紀子, 武田祐介, 鈴木修平, 加藤智也, 山田裕樹, 紺野恵理子, 吉岡孝志, 山川光徳, 園田順彦, 鈴木民夫, 西塚弘一, 山下英俊
- Organizer
  第137回山形眼科研究会
- Data Source
  KAKENHI-PROJECT-19K18870

1. OKADA Masashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results
2. 佐野町友美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 鈴木修平

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 北中千史

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Unregistered Unregistered 冨樫 敬太

Keita Togashi 冨樫 敬太

Research Projects

Research Products

Co-Researchers

Establishment of a novel treatment for uveal melanoma based on p53 pathway activationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Clarification of mechanisms for inhibition of retinoblastoma growth by CEP-1347Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Gemcitabine Cooperates with Everolimus to Inhibit the Growth of and Sensitize Malignant Meningioma Cells to Apoptosis Induced by Navitoclax, an Inhibitor of Anti-Apoptotic BCL-2 Family Proteins2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gemcitabine radiosensitization primes irradiated malignant meningioma cells for senolytic elimination by navitoclax.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles for hENT1 and dCK in gemcitabine sensitivity and malignancy of meningioma.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Targeting Folate Metabolism Is Selectively Cytotoxic to Glioma Stem Cells and Effectively Cooperates with Differentiation Therapy to Eliminate Tumor-Initiating Cells in Glioma Xenografts2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of the Lipid Droplet?Peroxisome Proliferator-Activated Receptor α Axis Suppresses Cancer Stem Cell Properties2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dexamethasone Sensitizes Cancer Stem Cells to Gemcitabine and 5-Fluorouracil by Increasing Reactive Oxygen Species Production through NRF2 Reduction.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lurasidone Sensitizes Cancer Cells to Osimertinib by Inducing Autophagy and Reduction of Survivin.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Metastatic Orbital Tumor From Breast Ductal Carcinoma With Neuroendocrine Differentiation Initially Presenting as Ocular Symptoms: A Case Report and Literature Review2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Therapeutic targeting of pancreatic cancer stem cells by dexamethasone modulation of the MKP-1-JNK axis.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of Retinoblastoma Cell Growth by CEP1347 Through Activation of the P53 Pathway2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Verteporfin inhibits oxidative phosphorylation and induces cell death specifically in glioma stem cells.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] 眼球摘出に至った脈絡膜悪性黒色腫症例の腫瘍検体の初代培養による細胞株樹立の試み2020

Author(s)

Organizer

Data Source

[Presentation] 眼球突出を契機として原発巣が判明した神経内分泌型乳管癌の眼窩転移の1例2019

Author(s)

Organizer

Data Source

Unregistered Unregistered 冨樫敬太

Keita Togashi 冨樫敬太