Nishide Masayuki 西出真之

Researcher Number	80812255
Other IDs	https://orcid.org/0000-0001-6060-1228
Affiliation (Current)	2026: 大阪大学, 大学院医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2024: 大阪大学, 大学院医学系研究科, 講師 2022 – 2023: 大阪大学, 大学院医学系研究科, 助教 2020: 大阪大学, 医学系研究科, 招へい教員 2018 – 2019: 大阪大学, 医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related
Keywords	Principal Investigator 血管炎 / シングルセル解析 / 自己免疫疾患 / 好酸球 / 好中球 / セマフォリン / アレルギー / 膠原病 / シングルセル / 全身性強皮症 … More / 副鼻腔炎 / インテグリン / 細胞外トラップ / 好酸球性副鼻腔炎 / ANCA関連血管炎 Less

シングルセル解析で紐解く免疫難病の臓器障害進展メカニズムとその治療Principal Investigator
- Principal Investigator
  
  西出真之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Osaka University
Pathological roles of immune guidance molecules that induce granulocytic cell deathPrincipal Investigator
- Principal Investigator
  
  Nishide Masayuki
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Osaka University
Pathological and therapeutic roles of semaphorin in refractory vasculitisPrincipal Investigator
- Principal Investigator
  
  Nishide Masayuki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Osaka University

All 2025 2024 2023 2022 2020 2019 2018

All Journal Article Presentation

[Journal Article] Spatial transcriptomics in autoimmune rheumatic disease: potential clinical applications and perspectives2025
- Author(s)
  Miyamoto Atsuko Tsujii, Shimagami Hiroshi, Kumanogoh Atsushi, Nishide Masayuki
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 45 Issue: 1
- DOI
  10.1186/s41232-025-00369-2
- Data Source
  KAKENHI-PROJECT-24K11596
[Journal Article] Single-cell analysis in rheumatic and allergic diseases: insights for clinical practice2024
- Author(s)
  Nishide Masayuki, Shimagami Hiroshi, Kumanogoh Atsushi
- Journal Title
  
  Nature Reviews Immunology
  
  Volume: 24 Issue: 11 Pages: 781-797
- DOI
  10.1038/s41577-024-01043-3
- Data Source
  KAKENHI-PROJECT-24K11596
[Journal Article] Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs2024
- Author(s)
  Yoshimitsu Nakanishi, Mayuko Izumi, (省略１７名), Sujin Kang, Atsushi Kumanogoh
- Journal Title
  
  Neuron
  
  Volume: 112 Issue: 17 Pages: 2955-2972
- DOI
  10.1016/j.neuron.2024.06.017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24153, KAKENHI-PROJECT-23K19454, KAKENHI-PROJECT-24K10597, KAKENHI-PROJECT-24K11596, KAKENHI-PROJECT-24K18366
[Journal Article] Neoself-antigens are the primary target for autoreactive T cells in human lupus.2024
- Author(s)
  Mori S, et al.
- Journal Title
  
  Cell
  
  Volume: 187 Issue: 21 Pages: 6071-6087
- DOI
  10.1016/j.cell.2024.08.025
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22H00450, KAKENHI-PROJECT-24H00610, KAKENHI-PROJECT-21K08344, KAKENHI-PROJECT-23K27671, KAKENHI-PROJECT-22K07090, KAKENHI-PROJECT-23K06564, KAKENHI-PROJECT-23K07887, KAKENHI-PROJECT-24K10271, KAKENHI-PROJECT-24K11492, KAKENHI-PROJECT-24K11596
[Journal Article] Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology2024
- Author(s)
  Hanako Yoshimura et al.
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 153 Issue: 5 Pages: 1268-1281
- DOI
  10.1016/j.jaci.2023.12.030
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KJ2494, KAKENHI-PROJECT-20K17180, KAKENHI-PROJECT-22K16361, KAKENHI-PROJECT-22K08283, KAKENHI-PROJECT-24K11342, KAKENHI-PROJECT-24K11596
[Journal Article] Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis2023
- Author(s)
  Nishide Masayuki、Nishimura Kei、Matsushita Hiroaki、Edahiro Ryuya、Inukai Sachi、Shimagami Hiroshi、Kawada Shoji、Kato Yasuhiro、Kawasaki Takahiro、Tsujimoto Kohei、Kamon Hokuto、Omiya Ryusuke、Okada Yukinori、Hattori Kunihiro、Narazaki Masashi、Kumanogoh Atsushi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1
- DOI
  10.1038/s41467-023-41328-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16361
[Journal Article] Single-cell Raman microscopy with machine learning highlights distinct biochemical features of neutrophil extracellular traps and necrosis2023
- Author(s)
  Lelliott Patrick Michael、Hobro Alison Jane、Pavillon Nicolas、Nishide Masayuki、Okita Yasutaka、Mizuno Yumiko、Obata Sho、Nameki Shinichiro、Yoshimura Hanako、Kumanogoh Atsushi、Smith Nicholas Isaac
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1
- DOI
  10.1038/s41598-023-36667-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K16361
[Journal Article] Continuous Use of Etanercept During Pregnancy Does Not Affect TNF-Alpha Levels in Umbilical Cord Blood2022
- Author(s)
  Nishide Masayuki、Yagita Mayu、Kumanogoh Atsushi
- Journal Title
  
  Biologics: Targets and Therapy
  
  Volume: Volume 16 Pages: 17-19
- DOI
  10.2147/btt.s358449
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05282, KAKENHI-PROJECT-22K16361
[Journal Article] Semaphorin 6D?expressing mesenchymal cells regulate IL-10 production by ILC2s in the lung2022
- Author(s)
  Naito Maiko、Nakanishi Yoshimitsu、Motomura Yasutaka、Takamatsu Hyota、Koyama Shohei、Nishide Masayuki、Naito Yujiro、Izumi Mayuko、Mizuno Yumiko、Yamaguchi Yuta、Nojima Satoshi、Okuzaki Daisuke、Kumanogoh Atsushi
- Journal Title
  
  Life Science Alliance
  
  Volume: 5 Issue: 11 Pages: 1486-1486
- DOI
  10.26508/lsa.202201486
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06903, KAKENHI-PROJECT-22K16361, KAKENHI-PROJECT-21J12329
[Journal Article] Cellular Adhesion Is a Controlling Factor in Neutrophil Extracellular Trap Formation Induced by Anti-Neutrophil Cytoplasmic Antibodies2022
- Author(s)
  Lelliott Patrick M.、Nishide Masayuki、Pavillon Nicolas、Okita Yasutaka、Shibahara Takayuki、Mizuno Yumiko、Yoshimura Hanako、Obata Sho、Kumanogoh Atsushi、Smith Nicholas I.
- Journal Title
  
  ImmunoHorizons
  
  Volume: 6 Issue: 2 Pages: 170-183
- DOI
  10.4049/immunohorizons.2200012
- Data Source
  KAKENHI-PROJECT-22K16361
[Journal Article] Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis2020
- Author(s)
  Tsuda T、Nishide M、Maeda Y、Hayama Y、Koyama S、Nojima S、Takamatsu H、Okuzaki D、Morita T、Nakatani T、Kato Y、Nakanishi Y、Futami Y、Suga Y、Naito Y、Konaka H、Satoh S、Naito M、Izumi M、Obata S、Nakatani A、Shikina T、Takeda K、Hayama M、Inohara H、Kumanogoh A
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 145 Issue: 3 Pages: 843-854
- DOI
  10.1016/j.jaci.2019.12.893
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16557, KAKENHI-PROJECT-18K16886, KAKENHI-PROJECT-17K11359, KAKENHI-PROJECT-19K09890, KAKENHI-PROJECT-18K16146
[Journal Article] OCTA, a sensitive screening for asymptomatic retinopathy, raises alarm over systemic involvements in patients with SLE2020
- Author(s)
  Mizuno Yumiko、Nishide Masayuki、Wakabayashi Taku、Nishida Kohji、Kumanogoh Atsushi
- Journal Title
  
  Annals of the Rheumatic Diseases
  
  Volume: 79 Issue: 2 Pages: e17-e17
- DOI
  10.1136/annrheumdis-2018-214751
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16146
[Presentation] Single cell analysis reveals the diversity of rheumatic diseases2024
- Author(s)
  西出真之
- Organizer
  第68回日本リウマチ学会　APLAR合同シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-24K11596
[Presentation] Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset ANCA associated vasculitis2024
- Author(s)
  Masayuki Nishide, Masashi Narazaki, Atsushi Kumanogoh
- Organizer
  第52回日本免疫学会
- Data Source
  KAKENHI-PROJECT-22K16361
[Presentation] 患者検体シングルセル解析に基づいた膠原病疾患多様性の理解2024
- Author(s)
  西出真之
- Organizer
  第121回日本内科学会総会・講演会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-24K11596
[Presentation] 抗MPO抗体を活用した新たなANCA関連血管炎マウスモデルの樹立と治療への応用2024
- Author(s)
  西出真之、水野裕美子、熊ノ郷淳
- Organizer
  第5回血管炎病因病態研究会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16361
[Presentation] 免疫難病患者検体の多層シングルセル解析から臨床像の多様性を理解する2024
- Author(s)
  西出真之
- Organizer
  第45回日本炎症・再生医学会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-24K11596
[Presentation] Single Cell Multi-Omics Elucidates Distinct Sub-Phenotypes of Microscopic Polyangiitis2024
- Author(s)
  西出真之
- Organizer
  アメリカリウマチ学会The JCR-ACR Scientific Session
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K11596
[Presentation] Bridging Single Cell Analysis with Clinical Insights for ANCA-Associated Vasculitis2024
- Author(s)
  西出真之
- Organizer
  Federation of Clinical Immunology Societies
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K11596
[Presentation] Complicate, Complement, Comprehension～補体制御の温故知新～2024
- Author(s)
  西出真之
- Organizer
  第33回日本リウマチ学会近畿支部学術集会　シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-24K11596
[Presentation] Different immunological phenotypes of microscopic polyangiitis identified by single-cell multi-omics analysis2024
- Author(s)
  西出真之
- Organizer
  第68回日本リウマチ学会　International Concurrent Workshop
- Data Source
  KAKENHI-PROJECT-24K11596
[Presentation] Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis2023
- Author(s)
  Masayuki Nishide, Atsushi Kumanogoh
- Organizer
  第25回アジア太平洋リウマチ学会
- Data Source
  KAKENHI-PROJECT-22K16361
[Presentation] Combination of monoclonal anti-MPO antibodies forms complexes to induce small-vessel vasculitis2023
- Author(s)
  Masayuki Nishide, Yumiko Mizuno, Atsushi Kumanogoh
- Organizer
  第67回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-22K16361
[Presentation] 患者検体シングルセル解析を基盤とした顕微鏡的多発血管炎に特徴的な細胞集団の同定2023
- Author(s)
  西出真之、熊ノ郷淳
- Organizer
  第51回日本臨床免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16361
[Presentation] 患者末梢血シングルセル解析によるANCA関連血管炎の層別化と実臨床への応用2023
- Author(s)
  西出真之、楢崎雅司、熊ノ郷淳
- Organizer
  第44回日本炎症・再生医学会
- Data Source
  KAKENHI-PROJECT-22K16361
[Presentation] Semaphorin 7A plays a critical role in the growth of allergic nasal polyps by inducing eosinophil extracellular traps2022
- Author(s)
  西出真之
- Organizer
  日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-22K16361
[Presentation] 臨床医に知っておいてもらいたい基礎研究の楽しみ方2022
- Author(s)
  西出真之
- Organizer
  日本リウマチ学会近畿支部地方会
- Invited
- Data Source
  KAKENHI-PROJECT-22K16361
[Presentation] The role of semaphorins in the regulation of granulocytic inflammation2020
- Author(s)
  Masayuki Nishide
- Organizer
  第64回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-18K16146
[Presentation] ‘Semaphorins and their involvement in the pathogenesis of autoimmune vasculitis’2019
- Author(s)
  Masayuki Nishide
- Organizer
  第48回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K16146
[Presentation] ‘Semaphorins and their involvement in the pathogenesis of autoimmune vasculitis’2019
- Author(s)
  Masayuki Nishide
- Organizer
  第63回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-18K16146
[Presentation] ‘Semaphorins and their involvement in the pathogenesis of autoimmune vasculitis’2019
- Author(s)
  Masayuki Nishide
- Organizer
  EMBO Meeting 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16146
[Presentation] 好中球活性化制御分子を標的としたANCA 関連血管炎の病態解析と治療への挑戦2019
- Author(s)
  西出真之
- Organizer
  第5回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18K16146
[Presentation] 自己免疫疾患の病態におけるセマフォリン分子の意義と作用2018
- Author(s)
  西出　真之
- Organizer
  第４６回日本臨床免疫学会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16146
[Presentation] Semaphorins and their involvement in the pathogenesis of autoimmune vasculitis2018
- Author(s)
  西出　真之
- Organizer
  第４７回日本免疫学会
- Data Source
  KAKENHI-PROJECT-18K16146
[Presentation] 好中球活性化制御分子を標的とした ANCA関連血管炎の疾患特異的治療への挑戦2018
- Author(s)
  西出　真之
- Organizer
  第４回JCRベーシックリサーチカンファレンス
- Data Source
  KAKENHI-PROJECT-18K16146
[Presentation] 好中球活性化制御分子を標的とした ANCA関連血管炎の疾患特異的治療への挑戦2018
- Author(s)
  西出　真之
- Organizer
  第４回日本骨免疫学会
- Data Source
  KAKENHI-PROJECT-18K16146

1. 熊郷淳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 野島聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 姜秀辰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nishide Masayuki 西出 真之

Research Projects

Research Products

Co-Researchers

シングルセル解析で紐解く免疫難病の臓器障害進展メカニズムとその治療Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathological roles of immune guidance molecules that induce granulocytic cell deathPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathological and therapeutic roles of semaphorin in refractory vasculitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Spatial transcriptomics in autoimmune rheumatic disease: potential clinical applications and perspectives2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-cell analysis in rheumatic and allergic diseases: insights for clinical practice2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Semaphorin 6D tunes amygdalar circuits for emotional, metabolic, and inflammatory outputs2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neoself-antigens are the primary target for autoreactive T cells in human lupus.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Galectin-10 in serum extracellular vesicles reflects asthma pathophysiology2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-cell multi-omics analysis identifies two distinct phenotypes of newly-onset microscopic polyangiitis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Single-cell Raman microscopy with machine learning highlights distinct biochemical features of neutrophil extracellular traps and necrosis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Continuous Use of Etanercept During Pregnancy Does Not Affect TNF-Alpha Levels in Umbilical Cord Blood2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Semaphorin 6D?expressing mesenchymal cells regulate IL-10 production by ILC2s in the lung2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular Adhesion Is a Controlling Factor in Neutrophil Extracellular Trap Formation Induced by Anti-Neutrophil Cytoplasmic Antibodies2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pathological and therapeutic implications of eosinophil-derived semaphorin 4D in eosinophilic chronic rhinosinusitis2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] OCTA, a sensitive screening for asymptomatic retinopathy, raises alarm over systemic involvements in patients with SLE2020

Author(s)

Journal Title

Nishide Masayuki 西出真之