Hasegawa Takuya 長谷川拓也

Researcher Number	80813287
Other IDs
Affiliation (Current)	2026: 新潟薬科大学, 薬学部, 助教
Affiliation (based on the past Project Information) *help	2018 – 2025: 新潟薬科大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related Except Principal Investigator Basic Section 47040:Pharmacology-related
Keywords	Principal Investigator 悪液質 / 骨転移 / プレキシン / セマフォリン Except Principal Investigator グリア細胞 / 脊髄 / DREADD / ガストリン放出ペプチド / TRPチャネル / 胆汁うっ滞 … More / TRPV4 / グルココルチコイド / 表皮 / 胆汁うっ滞性そう痒 / そう痒 Less

がん悪液質の腫瘍骨格筋連関の制御に対するセマフォリンの作用機構の解明Principal Investigator
- Principal Investigator
  
  長谷川拓也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Niigata University of Pharmacy and Medical and Life Sciences
Molecular mechanisms of semaphorins in the regulation of cancer cachexiaPrincipal Investigator
- Principal Investigator
  
  Hasegawa Takuya
- Project Period (FY)
  2019 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Niigata University of Pharmacy and Medical and Life Sciences
Elucidation of the molecular mechanisms underlying persistent pruritus in primary biliary cholangitis
- Principal Investigator
  
  Maeda Takehiko
- Project Period (FY)
  2018 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Niigata University of Pharmacy and Medical and Life Sciences

All 2025 2024 2023 2022 2020 2019

All Journal Article Presentation

[Journal Article] Semaphorin3A Knockdown Upregulates miR-20b-5p to Suppress Cyclin D1 expression and Cell Proliferation in High Bone-Metastatic Lung Cancer Cell2025
- Author(s)
  Hasegawa Takuya、Asano Yoshihisa、Maeda Takehiko
- Journal Title
  
  J. hard tissue biol.
  
  Volume: 34 Issue: 2 Pages: 49-56
- DOI
  10.2485/jhtb.34.49
- ISSN
  1341-7649, 1880-828X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16964
[Journal Article] Autocrine Semaphorin 6B Signaling Is Essential for Tumorigenesis in Lung Cancer2025
- Author(s)
  Yamada Daisuke、Hasegawa Takuya、Kawahara Kohichi、Maeda Takehiko
- Journal Title
  
  BPB Reports
  
  Volume: 8 Issue: 1 Pages: 18-22
- DOI
  10.1248/bpbreports.8.1_18
- ISSN
  2434-432X
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16964
[Journal Article] Characterization of a Cancer-Induced Bone Pain Model for Use as a Model of Cancer Cachexia2024
- Author(s)
  Hasegawa Takuya、Kawahara Kohichi、Sato Koji、Asano Yoshihisa、Maeda Takehiko
- Journal Title
  
  Current Issues in Molecular Biology
  
  Volume: 46 Issue: 12 Pages: 13364-13382
- DOI
  10.3390/cimb46120797
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16964
[Journal Article] Truncated <scp>GPNMB</scp>, a microglial transmembrane protein, serves as a scavenger receptor for oligomeric β‐amyloid peptide<sub>1‐42</sub> in primary type 1 microglia2024
- Author(s)
  Kawahara Kohichi、Hasegawa Takuya、Hasegawa Noa、Izumi Taisei、Sato Koji、Sakamaki Toshiyuki、Ando Masayuki、Maeda Takehiko
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: in press Issue: 7 Pages: 1317-1339
- DOI
  10.1111/jnc.16078
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16964, KAKENHI-PROJECT-18K06707
[Journal Article] MicroRNA-205-5p inhibits three-dimensional spheroid proliferation of ErbB2-overexpressing breast epithelial cells through direct targeting of CLCN3.2019
- Author(s)
  Takeno Takayoshi, Hasegawa Takuya, Hasegawa Hiroki, Ueno Yasuyuki, Hamataka Ryo, Nakajima Aya, Okubo Junji, Sato Koji, Sakamaki Toshiyuki
- Journal Title
  
  PeerJ
  
  Volume: 7 Pages: e7799-e7799
- DOI
  10.7717/peerj.7799
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] 悪液質動物モデルの脂肪組織におけるセマフォリンの発現解析2024
- Author(s)
  高橋希、髙橋蓮、川島優希、長谷川拓也、前田武彦
- Organizer
  第68回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] 悪液質動物の骨格筋におけるセマフォリンの発現解析2024
- Author(s)
  川島優希、高橋希、髙橋蓮、長谷川拓也、前田武彦
- Organizer
  第68回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] 癌性骨痛モデルマウスにおける TRPA1 の機能的役割2024
- Author(s)
  坪谷秋桜、長谷川拓也、前田武彦
- Organizer
  第68回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] がん悪液質におけるサルコペニアの分子機構2024
- Author(s)
  長谷川拓也
- Organizer
  第68回日本薬学会関東支部大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] がん骨移植による悪液質モデルマウスにおける炎症マーカーの発現解析2024
- Author(s)
  髙橋蓮、高橋希、川島優希、長谷川拓也、前田武彦
- Organizer
  第68回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] アルツハイマー病モデルマウスの脳内アミロイドβ蓄積量に対するGpnmb遺伝子の影響2023
- Author(s)
  川原浩一、鈴木琉菜、伴颯太朗、門澤涼、五十嵐知奈、若林舞、戸田洸、長谷川拓也、前田武彦
- Organizer
  日本薬学会第143年会（札幌）
- Data Source
  KAKENHI-PROJECT-18K06707
[Presentation] 肺がん細胞株骨移植による雄性悪液質モデルマウスの性状解析2023
- Author(s)
  長谷川拓也、川原浩一、前田武彦
- Organizer
  第67回日本薬学会関東支部大会
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] 胆汁うっ滞性掻痒モデルのそう痒行動におけるTRPチャネルの機能的関与2022
- Author(s)
  長谷川拓也,斎須拓哉,藤原関斗,川原浩一,前田武彦
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] 肺がん細胞株骨移植による雄性悪液質モデルマウスの性状解析2022
- Author(s)
  山本蒼、長谷川拓也、川原浩一、前田武彦
- Organizer
  第165回新潟薬学会
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] 胆汁うっ滞性掻痒モデルのそう痒行動におけるTRPチャネルの機能的関与2022
- Author(s)
  長谷川拓也，斎須拓哉，藤原関斗，川原浩一，前田武彦
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06707
[Presentation] アルツハイマー病モデルマウスにおけるGpnmb遺伝子の機能解析2020
- Author(s)
  川原浩一、熊倉夏希、小嶋雪菜、長谷川拓也、前田武彦
- Organizer
  第93回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-18K06707
[Presentation] 肺がん骨移植による悪液質モデルの作製と解析2020
- Author(s)
  長谷川拓也、山崎知槻、羽田裕介、川原浩一、前田武彦
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-18K06707
[Presentation] 肺がん骨移植による悪液質モデル作製と解析2019
- Author(s)
  長谷川拓也、山崎知槻、羽田裕介、川原浩一、前田武彦
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K16964
[Presentation] 肺がん骨移植による悪液質モデル作製と解析2019
- Author(s)
  長谷川拓也、山崎知槻、羽田裕介、川原浩一、前田武彦
- Organizer
  日本薬学会第140年会
- Data Source
  KAKENHI-PROJECT-19K16964

1. Maeda Takehiko (50271010)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. 川原浩一 (10347015)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results

Hasegawa Takuya 長谷川 拓也

Research Projects

Research Products

Co-Researchers

がん悪液質の腫瘍骨格筋連関の制御に対するセマフォリンの作用機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms of semaphorins in the regulation of cancer cachexiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanisms underlying persistent pruritus in primary biliary cholangitis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Semaphorin3A Knockdown Upregulates miR-20b-5p to Suppress Cyclin D1 expression and Cell Proliferation in High Bone-Metastatic Lung Cancer Cell2025

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Autocrine Semaphorin 6B Signaling Is Essential for Tumorigenesis in Lung Cancer2025

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Characterization of a Cancer-Induced Bone Pain Model for Use as a Model of Cancer Cachexia2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Truncated <scp>GPNMB</scp>, a microglial transmembrane protein, serves as a scavenger receptor for oligomeric β‐amyloid peptide<sub>1‐42</sub> in primary type 1 microglia2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MicroRNA-205-5p inhibits three-dimensional spheroid proliferation of ErbB2-overexpressing breast epithelial cells through direct targeting of CLCN3.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] 悪液質動物モデルの脂肪組織におけるセマフォリンの発現解析2024

Author(s)

Organizer

Data Source

[Presentation] 悪液質動物の骨格筋におけるセマフォリンの発現解析2024

Author(s)

Organizer

Data Source

[Presentation] 癌性骨痛モデルマウスにおける TRPA1 の機能的役割2024

Author(s)

Organizer

Data Source

[Presentation] がん悪液質におけるサルコペニアの分子機構2024

Author(s)

Organizer

Data Source

[Presentation] がん骨移植による悪液質モデルマウスにおける炎症マーカーの発現解析2024

Author(s)

Organizer

Data Source

[Presentation] アルツハイマー病モデルマウスの脳内アミロイドβ蓄積量に対するGpnmb遺伝子の影響2023

Author(s)

Organizer

Data Source

[Presentation] 肺がん細胞株骨移植による雄性悪液質モデルマウスの性状解析2023

Author(s)

Organizer

Data Source

[Presentation] 胆汁うっ滞性掻痒モデルのそう痒行動におけるTRPチャネルの機能的関与2022

Hasegawa Takuya 長谷川拓也