Kokaji Toshiya 小鍛治俊也

Researcher Number	80822551
Other IDs
Affiliation (Current)	2025: 奈良先端科学技術大学院大学, データ駆動型サイエンス創造センター, 助教
Affiliation (based on the past Project Information) *help	2025: 奈良先端科学技術大学院大学, データ駆動型サイエンス創造センター, 助教 2021 – 2023: 奈良先端科学技術大学院大学, データ駆動型サイエンス創造センター, 助教
Review Section/Research Field	Principal Investigator Basic Section 43050:Genome biology-related / Basic Section 54040:Metabolism and endocrinology-related
Keywords	Principal Investigator シミュレーション / ヒストン修飾 / ポリコーム複合体 / マルチオミクス / インスリン / 肥満 / 臓器連関 / トランスオミクス

ポリコーム複合体による双安定性発現制御機構の分子的実体の解明Principal Investigator
- Principal Investigator
  
  小鍛治俊也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Nara Institute of Science and Technology
Transomics analysis of glucose-responsive metabolic regulation through crosstalk between the liver and muscle and its alterations associated with obesityPrincipal Investigator
- Principal Investigator
  
  Kokaji Toshiya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Nara Institute of Science and Technology

All 2024 2023 2022

All Journal Article Presentation

[Journal Article] Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity.2024
- Author(s)
  Bai Y, Morita K, Kokaji T, Hatano A, Ohno S, Egami R, Pan Y, Li D, Yugi K, Uematsu S, Inoue H, Inaba Y, Suzuki Y, Matsumoto M, Takahashi M, Izumi Y, Bamba T, Hirayama A, Soga T, Kuroda S*.
- Journal Title
  
  iScience
  
  Volume: 27(3) Issue: 3 Pages: 109121-109121
- DOI
  10.1016/j.isci.2024.109121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K18924, KAKENHI-PROJECT-22K19545, KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-21H04759, KAKENHI-PLANNED-22H05185, KAKENHI-PROJECT-23K24764, KAKENHI-PROJECT-23K27996
[Journal Article] DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle2023
- Author(s)
  Maehara H.、Kokaji T.、Hatano A.、Suzuki Y.、Matsumoto M.、Nakayama K. I.、Egami R.、Tsuchiya T.、Ozaki H.、Morita K.、Shirai M.、Li D.、Terakawa A.、Uematsu S.、Hironaka K.、Ohno S.、Kubota H.、Araki H.、Miura F.、Ito T.、Kuroda S.
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 19118-19118
- DOI
  10.1038/s41598-023-46393-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K17992, KAKENHI-PROJECT-20K19915, KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-21H04759, KAKENHI-PROJECT-23K23870
[Journal Article] Acquisition of neural fate by combination of BMP blockade and chromatin modification2023
- Author(s)
  Ong Agnes Lee Chen、Kokaji Toshiya、Kishi Arisa、Takihara Yoshihiro、Shinozuka Takuma、Shimamoto Ren、Isotani Ayako、Shirai Manabu、Sasai Noriaki
- Journal Title
  
  iScience
  
  Volume: 26 Issue: 10 Pages: 107887-107887
- DOI
  10.1016/j.isci.2023.107887
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-20H03263
[Journal Article] Optogenetic decoding of Akt2-regulated metabolic signaling pathways in skeletal muscle cells using transomics analysis2023
- Author(s)
  Kawamura Genki、Kokaji Toshiya、Kawata Kentaro、Sekine Yuka、Suzuki Yutaka、Soga Tomoyoshi、Ueda Yoshibumi、Endo Mizuki、Kuroda Shinya、Ozawa Takeaki
- Journal Title
  
  Science Signaling
  
  Volume: 16 Issue: 773 Pages: 773-773
- DOI
  10.1126/scisignal.abn0782
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-22K14779, KAKENHI-PROJECT-20K15395, KAKENHI-PROJECT-18H03979, KAKENHI-PROJECT-19H00900, KAKENHI-PROJECT-21H04759, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300
[Journal Article] Comparison of hepatic responses to glucose perturbation between healthy and obese mice based on the edge type of network structures2023
- Author(s)
  Ito Yuki、Uda Shinsuke、Kokaji Toshiya、Hirayama Akiyoshi、Soga Tomoyoshi、Suzuki Yutaka、Kuroda Shinya、Kubota Hiroyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 4758-4758
- DOI
  10.1038/s41598-023-31547-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-20H03237
[Journal Article] Trans-omics analysis of insulin action reveals a cell growth subnetwork which co-regulates anabolic processes2022
- Author(s)
  Terakawa Akira、Hu Yanhui、Kokaji Toshiya、Yugi Katsuyuki、Morita Keigo、Ohno Satoshi、Pan Yifei、Bai Yunfan、Parkhitko Andrey A.、Ni Xiaochun、Asara John M.、Bulyk Martha L.、Perrimon Norbert、Kuroda Shinya
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 5 Pages: 104231-104231
- DOI
  10.1016/j.isci.2022.104231
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K14467, KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-18H03979, KAKENHI-PROJECT-21H04759, KAKENHI-PLANNED-18H05431, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300
[Journal Article] In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states.2022
- Author(s)
  Kokaji T, Eto M, Hatano A, Yugi K, Morita K, Ohno S, Fujii M, Hironaka KI, Ito Y, Egami R, Uematsu S, Terakawa A, Pan Y, Maehara H, Li D, Bai Y, Tsuchiya T, Ozaki H, Inoue H, Kubota H, Suzuki Y, Hirayama A, Soga T, Kuroda S.
- Journal Title
  
  Sci Rep
  
  Volume: 12 Issue: 1 Pages: 13719-13719
- DOI
  10.1038/s41598-022-17964-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19545, KAKENHI-PROJECT-20K19915, KAKENHI-PROJECT-21K14467, KAKENHI-PROJECT-21K16349, KAKENHI-PROJECT-20H03237, KAKENHI-PROJECT-20H04102, KAKENHI-PROJECT-19K20382, KAKENHI-PROJECT-19K20394, KAKENHI-PROJECT-18H03979, KAKENHI-PLANNED-18H05431, KAKENHI-ORGANIZER-17H06299, KAKENHI-PLANNED-17H06300
[Presentation] マウスの肝臓と骨格筋における臓器内および臓器間代謝制御とその肥満による制御異常のトランスオミクス解析2022
- Author(s)
  小鍛治俊也, 幡野敦, 伊藤有紀, 柚木克之, 衛藤樹, 守田啓悟, 大野聡, 藤井雅史, 廣中謙一, 江上陸, 寺川瑛, 土屋貴穂, 尾崎遼, 井上啓, 宇田新介, 久保田浩行, 鈴木穣, 池田和貴, 有田誠, 松本雅記, 中山敬一, 平山明由, 曽我朋義, 黒田真也
- Organizer
  第45回日本分子生物学年会
- Data Source
  KAKENHI-PROJECT-21K16349

1. 尾崎遼

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 大野聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 和泉自泰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 井上啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kokaji Toshiya 小鍛治 俊也

Research Projects

Research Products

Co-Researchers

ポリコーム複合体による双安定性発現制御機構の分子的実体の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Transomics analysis of glucose-responsive metabolic regulation through crosstalk between the liver and muscle and its alterations associated with obesityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Trans-omic analysis reveals opposite metabolic dysregulation between feeding and fasting in liver associated with obesity.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA hypomethylation characterizes genes encoding tissue-dominant functional proteins in liver and skeletal muscle2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acquisition of neural fate by combination of BMP blockade and chromatin modification2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optogenetic decoding of Akt2-regulated metabolic signaling pathways in skeletal muscle cells using transomics analysis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of hepatic responses to glucose perturbation between healthy and obese mice based on the edge type of network structures2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Trans-omics analysis of insulin action reveals a cell growth subnetwork which co-regulates anabolic processes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states.2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] マウスの肝臓と骨格筋における臓器内および臓器間代謝制御とその肥満による制御異常のトランスオミクス解析2022

Author(s)

Organizer

Data Source

Kokaji Toshiya 小鍛治俊也