Okagawa Tomohiro 岡川朋弘

Researcher Number	80829036
Other IDs
Affiliation (Current)	2023: 北海道大学, 獣医学研究院, 特任助教
Affiliation (based on the past Project Information) *help	2019 – 2022: 北海道大学, 獣医学研究院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related Except Principal Investigator Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42010:Animal production science-related
Keywords	Principal Investigator 牛伝染性リンパ腫 / BLV / 牛白血病 / 免疫抑制受容体 / T細胞 / 新規制御法 / 免疫活性化 / 免疫抑制 / 発症機序 / 宿主遺伝子 / キメラ転写産物 … More Except Principal Investigator … More 家畜悪性感染症 / 免疫破綻 / 免疫疲弊化 / 免疫チェックポイント / プロスタグランジンE2 / マダニ / 慢性感染症 / ウシ / BLV / フォーミーウイルス / ワクチン / レトロウイルスベクター / 牛 Less

Construction of animal foamy virus vector and development of enzootic bovine leukosis vaccine
- Principal Investigator
  
  目堅博久
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  University of Miyazaki
Mechanism of tumorigenesis in bovine leukemia initiated by chimeric transcripts of BLV-host genesPrincipal Investigator
- Principal Investigator
  
  岡川朋弘
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Hokkaido University
Development of immunotherapy targeting immunoinhibitory receptors for control of bovine leukemia virus infectionPrincipal Investigator
- Principal Investigator
  
  Okagawa Tomohiro
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Hokkaido University
Analysis of the molecular mechanism for immunosuppression in malignant infectious diseases of livestock and the development of a novel control method
- Principal Investigator
  
  今内覚
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Hokkaido University

All 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Enhancement of interleukin-2 production by bovine peripheral blood mononuclear cells treated with the combination of anti-programmed death-ligand 1 and cytotoxic T lymphocyte antigen 4 chimeric monoclonal antibodies2022
- Author(s)
  WATARI Kei、KONNAI Satoru、OKAGAWA Tomohiro、MAEKAWA Naoya、SAJIKI Yamato、KATO Yukinari、SUZUKI Yasuhiko、MURATA Shiro、OHASHI Kazuhiko
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 84 Issue: 1 Pages: 6-15
- DOI
  10.1292/jvms.21-0552
- NAID
  130008139952
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172
[Journal Article] Estradiol-induced immune suppression via prostaglandin E2 during parturition in bovine leukemia virus-infected cattle2022
- Author(s)
  Sajiki Yamato、Konnai Satoru、Okagawa Tomohiro、Maekawa Naoya、Goto Shinya、Kohara Junko、Nitanai Atsushi、Takahashi Hirofumi、Kubota Kentaro、Takeda Hiroshi、Murata Shiro、Ohashi Kazuhiko
- Journal Title
  
  PLOS One
  
  Volume: 17 Pages: 1-13
- DOI
  10.1371/journal.pone.0263660
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172
[Journal Article] Cross-species reactivity of antibodies against Ixodes persulcatus ferritin 2 to Rhipicephalus microplus2021
- Author(s)
  Xavier AM, Konnai S, Parizi FP, Githaka WN, Isezaki M, Goto S, Fujisawa S, Yamada S, Okagawa T, Maekawa N, Logullo C, Silva Vaz J r I, Murata S, Ohashi K.
- Journal Title
  
  Jpn J Vet Res.
  
  Volume: 69(1) Pages: 57-65
- NAID
  120006994840
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] 発酵哺乳飼料による子牛の腸炎防御効果の直接証明2021
- Author(s)
  今内覚, 岡川朋弘
- Journal Title
  
  JATAFFジャーナル
  
  Volume: 9(10) Pages: 21-26
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] The enhancement of Th1 immune response by anti-PD-L1 antibody in cattle infected with <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i>2021
- Author(s)
  Sajiki, Y., Konnai, S., Nagata, R., Kawaji, S., Nakamura, H., Fujisawa, S., Okagawa, T., Mawkawa, N., Kato, Y., Suzuki, Y., Murata, S., Mori, Y., Ohashi, K.
- Journal Title
  
  J. Vet. Med. Sci.
  
  Volume: 83 Issue: 2 Pages: 162-166
- DOI
  10.1292/jvms.20-0590
- NAID
  130007990713
- ISSN
  0916-7250, 1347-7439
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-19K15993
[Journal Article] Tick saliva-induced programmed death-1 and PD-ligand 1 and its related host immunosuppression2021
- Author(s)
  Sajiki, Y., Konnai, S., Ikenaka, Y., Gulay, K. C. M., Kobayashi, A. Parizi, L. F., Joo, B. C., Watari, K., Fujisawa, S., Okagawa, T., Maekawa, N., Logullo, C.,da Silva Vaz, I.,Murata, S., Ohashi, K.
- Journal Title
  
  Sci Rep.
  
  Volume: 11 Pages: 1063-1063
- DOI
  10.1038/s41598-020-80251-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-19J21826
[Journal Article] Direct evidence of the preventive effect of milk replacer-based probiotic feeding in calves against severe diarrhea2021
- Author(s)
  Kayasaki, F., Okagawa, T., Konnai, S., Kohara, J., Sajiki, Y., Watari, K., Ganbaatar, O., Goto, S., Nakamura, H., Shimakura, H., Minato, E., Kobayashi, A., Kubota, M., Terasaki, N., Takeda, A., Noda, H., Honma, M., Maekawa, N., Murata, S., Ohashi, K.
- Journal Title
  
  Vet Microbiol.
  
  Volume: 254 Pages: 108976-108976
- DOI
  10.1016/j.vetmic.2020.108976
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-19J21826
[Journal Article] 牛伝染性リンパ腫の病態発生機序解析を基盤とする新制御法の試み2021
- Author(s)
  今内覚, 岡川朋弘, 前川直也, 村田史郎, 大橋和彦
- Journal Title
  
  家畜衛生学雑誌
  
  Volume: 47(3) Pages: 147-150
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] Intrauterine infection with Mycobacterium avium subsp. paratuberculosis in pregnant cattle diagnosed with Johne’s disease2021
- Author(s)
  Taniguchi Y, Konnai S, Sakakibara S, Yamamoto A, Okagawa T, Maekawa N, Murata S, Ohashi K.
- Journal Title
  
  Jpn J Vet Res.
  
  Volume: 69(1) Pages: 51-55
- NAID
  120006994839
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] Prostaglandin-related immune suppression in cattle.2021
- Author(s)
  Sajiki Y.、Konnai S.、Ikenaka Y.、Okagawa T.、Maekawa N.、Logullo C.、da Silva Vaz I.、Murata S.、Ohashi K.
- Journal Title
  
  Vet Immunol Immunopathol.
  
  Volume: 236 Pages: 110238-110238
- DOI
  10.1016/j.vetimm.2021.110238
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K15993, KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172
[Journal Article] プロバイオティクスで子牛を下痢から守る～高品質で安全な発酵代用乳～2021
- Author(s)
  岡川朋弘, 今内覚
- Journal Title
  
  MPアグロジャーナル
  
  Volume: 45(7) Pages: 34-37
- NAID
  40022636371
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] Prostaglandin-related immune suppression in cattle2021
- Author(s)
  Sajiki Y, Konnai S, Ikenaka Y, Okagawa T, Maekawa N, Logullo C, da Silva Vaz Jr I, Murata S, Ohashi K.
- Journal Title
  
  Vet Immunol Immunopath.
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] 子牛下痢症対策のアップデート：子牛下痢症への発酵代用乳の適応2021
- Author(s)
  岡川朋弘, 今内覚
- Journal Title
  
  臨床獣医
  
  Volume: 9 Pages: 34-38
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] A TLR7 agonist activates bovine Th1 response and exerts antiviral activity against bovine leukemia virus2021
- Author(s)
  Sajiki, Y., Konnai, S., Okagawa, T., Maekawa, N., Nakamura, H., Kato, Y., Suzuki, Y., Murata, S., Ohashi, K.
- Journal Title
  
  Dev Comp Immunol.
  
  Volume: 114 Pages: 103847-103847
- DOI
  10.1016/j.dci.2020.103847
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-19K15993
[Journal Article] Programmed death-ligand 1 expression in swine chronic infections and enhancement of interleukin-2 production via programmed death-1/programmed death-ligand 1 blockade2021
- Author(s)
  Ganbaatar, O., Konnai, S., Okagawa, T., Nojima, Y., Maekawa, N., Ichikawa, Y., Kobayashi, A., Shibahara, T., Yanagawa, Y., Higuchi, H., Kato, Y., Suzuki, Y., Murata, S., Ohashi, K.
- Journal Title
  
  Immun Inflamm Dis.
  
  Volume: 9 Pages: 1573-1583
- DOI
  10.1002/iid3.510
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172
[Journal Article] Molecular Epidemiology and Whole-Genome Analysis of Bovine Foamy Virus in Japan2021
- Author(s)
  Mekata Hirohisa、Okagawa Tomohiro、Konnai Satoru、Miyazawa Takayuki
- Journal Title
  
  Viruses
  
  Volume: 13 Pages: 1017-1017
- DOI
  10.3390/v13061017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03150, KAKENHI-PROJECT-19KK0172
[Journal Article] Identification and functional analysis of ferritin 2 from the Taiga tick Ixodes persulcatus Schulze2020
- Author(s)
  Githaka, N. W., Konnai, S., Isezaki, M., Goto, S., Xavier, M. A., Fujisawa, S., Yamada, S., Okagawa, T., Maekawa, N., Logullo, C., da Silva Vaz, I., Murata, S., Ohashi, K. 4.巻 11
- Journal Title
  
  Ticks Tick Borne Dis.
  
  Volume: 11 Pages: 101547-101547
- DOI
  10.1016/j.ttbdis.2020.101547
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332
[Journal Article] The Suppression of Th1 Response by Inducing TGF-β1 From Regulatory T Cells in Bovine Mycoplasmosis2020
- Author(s)
  Sajiki Yamato、Konnai Satoru、Goto Shinya、Okagawa Tomohiro、Ohira Kosuke、Shimakura Honami、Maekawa Naoya、Gondaira Satoshi、Higuchi Hidetoshi、Tajima Motoshi、Hirano Yuki、Kohara Junko、Murata Shiro、Ohashi Kazuhiko
- Journal Title
  
  Front Vet Sci.
  
  Volume: 7 Pages: 2564-2569
- DOI
  10.3389/fvets.2020.609443
- NAID
  120007193553
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06425, KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-19K15993
[Journal Article] Clinical efficacy of the combined treatment of anti-PD-L1 rat-bovine chimeric antibody with a COX-2 inhibitor in calves infected with Mycoplasma bovis2020
- Author(s)
  Goto S, Konnai S, Hirano Y, Kohara J, Okagawa T, Maekawa N, Sajiki Y, Watari K, Minato E, Kobayashi A, Gondaira S, Higuchi H, Koiwa M, Tajima M, Taguchi E, Ishida M, Uemura R, Yamada S, Kaneko M, Kato Y, Yamamoto K, Toda M, Suzuki Y, Murata S, Ohashi K.
- Journal Title
  
  Jpn J Vet Res.
  
  Volume: 68(2) Pages: 77-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] 牛白血病の病態発生機序解析を基盤とする新制御法の試み2020
- Author(s)
  今内覚, 岡川朋弘, 前川直也, 村田史郎, 大橋和彦
- Journal Title
  
  畜産技術
  
  Volume: 784 Pages: 36-40
- Data Source
  KAKENHI-PROJECT-19K15993
[Journal Article] Clinical efficacy of the combined treatment of anti-PD-L1 rat-bovine chimeric antibody with a COX-2 inhibitor in calves infected with Mycoplasma bovis2020
- Author(s)
  Goto S, Konnai S, Hirano Y, Kohara J, Okagawa T, Maekawa N, Sajiki Y, Watari K, Minato E, Kobayashi A, Gondaira S, Higuchi H, Koiwa M, Tajima M, Taguchi E, Uemura R, Yamada S, Kaneko MK, Kato Y, Yamamoto K, Toda M, Suzuki Y, Murata S, Ohashi K
- Journal Title
  
  Japanese Journal of Veterinary Research
  
  Volume: 68 Issue: 2 Pages: 77-90
- DOI
  10.14943/jjvr.68.2.77
- NAID
  120006863178
- ISSN
  0047-1917
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K15993
[Journal Article] Immunosuppressive effects of sialostatin L1 and L2 isolated from the taiga tick Ixodes persulcatus Schulze2020
- Author(s)
  Sajiki Y, Konnai S, Ochi A, Okagawa T, Githaka N, Isezaki M, Yamada S, Ito T, Ando S, Kawabata H, Da Silva Vaz Jr I, Logullo C, Maekawa N, Murata S, Ohashi K.
- Journal Title
  
  Ticks and Tick-borne Diseases
  
  Volume: 11(2) Pages: 101332-101332
- DOI
  10.1016/j.ttbdis.2019.101332
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-18H02332
[Journal Article] PD-L1 expression in equine malignant melanoma and functional effects of PD-L1 blockade2020
- Author(s)
  Ganbaatar, O., Konnai, S. Okagawa, T., Nojima, Y., Maekawa, N., Minato, E., Kobayashi, A., Ando, R., Sasaki, N., Miyakoshi, D., Ichii, O., Kato, Y., Suzuki, Y., Murata, S., Ohashi, K.
- Journal Title
  
  PLoS One.
  
  Volume: 15
- DOI
  10.1371/journal.pone.0234218
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-19H03114
[Journal Article] 動物用抗体医薬品の開発および臨床研究2020
- Author(s)
  今内覚、岡川朋弘、前川直也、中島千絵、鈴木定彦、山本啓一、戸田幹洋、村田史郎、大橋和彦
- Journal Title
  
  日本動物用医薬品協会会報
  
  Volume: 67(2) Pages: 1-10
- NAID
  40022176977
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] Enhanced Immunotherapeutic Efficacy of Anti-PD-L1 Antibody in Combination with an EP4 Antagonist2020
- Author(s)
  Sajiki Yamato、Konnai Satoru、Cai Zimeng、Takada Kensuke、Okagawa Tomohiro、Maekawa Naoya、Fujisawa Sotaro、Kato Yukinari、Suzuki Yasuhiko、Murata Shiro、Ohashi Kazuhiko
- Journal Title
  
  Immunohorizons
  
  Volume: 4 Pages: 837-850
- DOI
  10.4049/immunohorizons.2000089
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21356, KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-17H03928, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-19H03114, KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-19K15993
[Journal Article] Upregulation of PD-L1 expression by prostaglandin E2 and the enhancement of IFN-γ by anti-PD-L1 antibody combined with a COX-2 inhibitor in Mycoplasma bovis infection2020
- Author(s)
  Goto Shinya、Konnai Satoru、Hirano Yuki、Kohara Junko、Okagawa Tomohiro、Maekawa Naoya、Sajiki Yamato、Watari Kei、Minato Erina、Kobayashi Atsuhi、et al.
- Journal Title
  
  Front Vet Sci
  
  Volume: 7 Pages: 12-12
- DOI
  10.3389/fvets.2020.00012
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K05963, KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-18J13237, KAKENHI-PROJECT-19J21826, KAKENHI-PROJECT-19K06425, KAKENHI-PROJECT-20K21357, KAKENHI-PROJECT-19K15993
[Journal Article] Clinical efficacy of the combined treatment of anti-PD-L1 rat-bovine chimeric antibody with a COX-2 inhibitor in calves infected with Mycoplasma bovis2020
- Author(s)
  Goto S, Konnai S, Hirano Y, Kohara J, Okagawa T, Maekawa N, Sajiki Y, Watari K, Minato E, Kobayashi A, Gondaira S, Higuchi H, Koiwa M, Tajima M, Taguchi E, Ishida M, Uemura R, Yamada S, Kaneko M, Kato Y, Yamamoto K, Toda M, Suzuki Y, Murata S, Ohashi K.
- Journal Title
  
  Jpn. J. Vet. Res
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] 牛白血病の病態発生機序解析を基盤とする新制御法の試み2020
- Author(s)
  今内覚, 岡川朋弘, 前川直也, 村田史郎, 大橋和彦
- Journal Title
  
  畜産技術
  
  Volume: 784) Pages: 36-40
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] Immune inhibitory function of bovine CTLA-4 and the effects of its blockade in IFN-γ production.2019
- Author(s)
  Watari K, Konnai S, Maekawa N, Okagawa T, Suzuki Y, Murata S, Ohashi K.
- Journal Title
  
  BMC Vet Res
  
  Volume: 15(1) Pages: 380-380
- DOI
  10.1186/s12917-019-2082-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19KK0172, KAKENHI-PROJECT-18H02332, KAKENHI-PROJECT-19H03114
[Journal Article] ダニ研究の最前線とダニ媒介性感染症制御の可能性を探る: 病原体伝播に関わるマダニ因子～マダニ唾液中の免疫抑制因子～2019
- Author(s)
  今内覚、岡川朋弘、前川直也、村田史郎、大橋和彦
- Journal Title
  
  Med. Entomol. Zool.
  
  Volume: 70(4) Pages: 189-197
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0172
[Journal Article] ウシマイコプラズマ感染症における免疫疲弊化2019
- Author(s)
  今内覚、後藤伸也、岡川朋弘、前川直也、村田史郎、大橋和彦
- Journal Title
  
  日本マイコプラズマ学会雑誌
  
  Volume: 46 Pages: 31-33
- Data Source
  KAKENHI-PROJECT-19KK0172
[Presentation] 牛伝染性リンパ腫発症母牛における子宮内感染の解析2021
- Author(s)
  嶋倉穂南、今内覚、岡川朋弘、中村隼人、神谷可菜、齋藤麻矢、前川直也、村田史郎、大橋和彦
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0172
[Presentation] 牛の慢性感染症に対する免疫チェックポイント阻害抗体薬の臨床研究2021
- Author(s)
  岡川朋弘
- Organizer
  第12回動物用ワクチン・バイオ医薬品研究会シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K15993
[Presentation] Expression and functional analysis of swine PD-1 /PD-L1 pathway2021
- Author(s)
  Ganbaatar O, Konnai S, Okagawa T, Nojima Y, Maekawa N, Ichikawa Y, Kobayashi A, Shibahara T, Yanagawa Y, Suzuki Y, Murata S, Ohashi K.
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0172
[Presentation] ウシCTLA-4ならびにPD-L1を標的とした抗体併用法による免疫増強効果の検討2021
- Author(s)
  渡　慧、今内覚、岡川朋弘、前川直也、村田史郎、鈴木定彦、大橋和彦
- Organizer
  第164回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0172
[Presentation] Enhanced production of IL-2 by combination of anti-Cytotoxic T Lymphocyte Antigen 4 chimeric antibody with Programmed Death Ligand 1 blockade2021
- Author(s)
  Watari K, Konnai S, Okagawa T, Maekawa N, Suzuki Y, Murata S, Ohashi K.
- Organizer
  The 9th Sapporo Summer Seminar for One Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0172
[Presentation] PD-L1 expression in swine chronic infections and enhancement of IL-2 production via PD-1/PD-L1 blockade2021
- Author(s)
  Ganbaatar O, Konnai S, Okagawa T, Maekawa N, Murata S, Ohashi K.
- Organizer
  The 9th Sapporo Summer Seminar for One Health
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0172
[Presentation] 牛白血病ウイルス感染症における免疫抑制受容体TIM-3の発現解析および機能解析2020
- Author(s)
  中村隼人、今内覚、岡川朋弘、佐治木大和、渡慧、神谷可菜、齋藤麻矢、前川直也、村田史郎、大橋和彦
- Organizer
  第163回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-19K15993
[Presentation] Functional analysis of bovine CTLA-4 in bovine leukemia virus infection2020
- Author(s)
  渡　慧、今内　覚、岡川朋弘、前川直也、村田史郎、大橋和彦
- Organizer
  リオグランデドスール連邦大学特別講演(リオグランデドスル連邦大学、ポルト・アレグレ、ブラジル)
- Invited
- Data Source
  KAKENHI-PROJECT-19KK0172
[Presentation] Enhanced immune efficacy of anti-Cytotoxic T Lymphocyte Antigen 4 chimeric antibody by combination with Programmed Death Ligand 1 blockade2020
- Author(s)
  Watari K, Konnai S, Okagawa T, Maekawa N, Suzuki Y, Murata S, Ohashi K.
- Organizer
  Sapporo Summer Symposium for One Health 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0172
[Presentation] Immunosuppressive function of prostaglandin E2 in cattle2020
- Author(s)
  佐治木大和、今内　覚、岡川朋弘、前川直也、村田史郎、大橋和彦
- Organizer
  リオグランデドスール連邦大学特別講演(リオグランデドスル連邦大学、ポルト・アレグレ、ブラジル)
- Invited
- Data Source
  KAKENHI-PROJECT-19KK0172
[Presentation] Characterization and functional analysis of swine PD-1 /PD-L1 pathway2020
- Author(s)
  Ganbaatar O, Konnai S, Okagawa T, Nojima Y, Maekawa N, Minato E, Kobayashi A, Ando R, Sasaki N, Miyakoshi D, Ichii O, Kato Y, Suzuki Y, Murata S, Ohashi K.
- Organizer
  Sapporo Summer Symposium for One Health 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0172

1. 今内覚 (40396304)

# of Collaborated Projects: 2 results

# of Collaborated Products: 38 results
2. 前川直也 (70829035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 34 results
3. 目堅博久 (90633264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. 齊藤暁 (30621792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKADA Kensuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 村田史郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results
7. 大橋和彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 11 results
8. 樋口豪紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 小林篤史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 宮沢孝幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okagawa Tomohiro 岡川 朋弘

Research Projects

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Co-Researchers

Construction of animal foamy virus vector and development of enzootic bovine leukosis vaccine

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Mechanism of tumorigenesis in bovine leukemia initiated by chimeric transcripts of BLV-host genesPrincipal Investigator

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Development of immunotherapy targeting immunoinhibitory receptors for control of bovine leukemia virus infectionPrincipal Investigator

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Analysis of the molecular mechanism for immunosuppression in malignant infectious diseases of livestock and the development of a novel control method

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[Journal Article] Enhancement of interleukin-2 production by bovine peripheral blood mononuclear cells treated with the combination of anti-programmed death-ligand 1 and cytotoxic T lymphocyte antigen 4 chimeric monoclonal antibodies2022

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[Journal Article] Estradiol-induced immune suppression via prostaglandin E2 during parturition in bovine leukemia virus-infected cattle2022

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[Journal Article] Cross-species reactivity of antibodies against Ixodes persulcatus ferritin 2 to Rhipicephalus microplus2021

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[Journal Article] 発酵哺乳飼料による子牛の腸炎防御効果の直接証明2021

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[Journal Article] The enhancement of Th1 immune response by anti-PD-L1 antibody in cattle infected with <i>Mycobacterium avium</i> subsp. <i>paratuberculosis</i>2021

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[Journal Article] Tick saliva-induced programmed death-1 and PD-ligand 1 and its related host immunosuppression2021

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[Journal Article] Direct evidence of the preventive effect of milk replacer-based probiotic feeding in calves against severe diarrhea2021

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[Journal Article] 牛伝染性リンパ腫の病態発生機序解析を基盤とする新制御法の試み2021

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[Journal Article] Intrauterine infection with Mycobacterium avium subsp. paratuberculosis in pregnant cattle diagnosed with Johne’s disease2021

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[Journal Article] Prostaglandin-related immune suppression in cattle.2021

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Okagawa Tomohiro 岡川朋弘

[Journal Article] プロバイオティクスで子牛を下痢から守る～高品質で安全な発酵代用乳～2021